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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936920:43,047...227,452
Ensembl chrNW_004936920:43,338...227,522
JBrowse link
G Aff4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936647:2,242,476...2,342,409
Ensembl chrNW_004936647:2,242,319...2,336,532
JBrowse link
G Ccnk cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936604:3,283,996...3,316,516
Ensembl chrNW_004936604:3,283,715...3,319,572
JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936512:6,567,663...6,588,107
Ensembl chrNW_004936512:6,562,974...6,588,409
JBrowse link
G Ccnt2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936469:40,799,428...40,837,462
Ensembl chrNW_004936469:40,803,819...40,837,433
JBrowse link
G Cdc73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277
JBrowse link
G Cdk9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936487:15,446,864...15,450,750
Ensembl chrNW_004936487:15,446,858...15,452,796
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936528:7,585,937...7,613,022
Ensembl chrNW_004936528:7,585,787...7,613,047
JBrowse link
G Eaf1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936473:2,950,321...2,963,560
Ensembl chrNW_004936473:2,949,692...2,963,554
JBrowse link
G Eaf2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936536:8,213,794...8,257,595
Ensembl chrNW_004936536:8,213,763...8,258,201
JBrowse link
G Ell elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936596:2,745,862...2,812,513
Ensembl chrNW_004936596:2,745,825...2,812,880
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936523:7,399,426...7,470,895
Ensembl chrNW_004936523:7,399,421...7,473,158
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936471:6,835,410...6,838,582
Ensembl chrNW_004936471:6,835,930...6,838,544
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936588:3,742,880...3,750,400
Ensembl chrNW_004936588:3,742,921...3,750,196
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936791:1,244,224...1,390,659
Ensembl chrNW_004936791:1,244,186...1,391,205
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936471:13,753,061...13,783,990
Ensembl chrNW_004936471:13,753,030...13,784,049
JBrowse link
G Mllt1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936588:3,619,480...3,678,532
Ensembl chrNW_004936588:3,619,493...3,669,854
JBrowse link
G Mllt3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004936652:2,040,685...2,309,059
Ensembl chrNW_004936652:2,044,874...2,308,832
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004936524:6,429,735...6,465,035
Ensembl chrNW_004936524:6,429,185...6,465,035
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004936833:920,683...928,047
Ensembl chrNW_004936833:920,674...928,047
JBrowse link
G Nelfa negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936477:21,442,493...21,459,999
Ensembl chrNW_004936477:21,442,380...21,464,005
JBrowse link
G Nelfb negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936669:726,731...738,714
Ensembl chrNW_004936669:726,658...738,848
JBrowse link
G Nelfcd negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936530:1,474,097...1,481,943
Ensembl chrNW_004936530:1,474,136...1,481,567
JBrowse link
G Nelfe negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936727:1,589,942...1,596,009
Ensembl chrNW_004936727:1,589,942...1,598,182
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936661:2,236,121...2,241,086
Ensembl chrNW_004936661:2,232,484...2,241,629
JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004936510:3,186,552...3,405,862
Ensembl chrNW_004936510:3,186,506...3,406,159
JBrowse link
G Rtf1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936471:4,770,060...4,829,562
Ensembl chrNW_004936471:4,770,063...4,829,578
JBrowse link
G Skic8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004936471:36,704,236...36,723,675
Ensembl chrNW_004936471:36,704,160...36,723,669
JBrowse link
G Ssrp1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936581:5,148,108...5,157,630
Ensembl chrNW_004936581:5,148,050...5,157,667
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936880:511,699...545,364
Ensembl chrNW_004936880:508,244...545,369
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936490:4,744,307...4,751,043
Ensembl chrNW_004936490:4,744,443...4,749,868
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936661:2,280,390...2,308,085
Ensembl chrNW_004936661:2,280,285...2,308,780
JBrowse link
G Tcea1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936496:877,311...918,191
Ensembl chrNW_004936496:877,773...918,175
JBrowse link
G Tcea2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936514:11,243,021...11,251,216
Ensembl chrNW_004936514:11,242,739...11,250,260
JBrowse link
G Tcea3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004936474:8,601,910...8,642,148
Ensembl chrNW_004936474:8,601,869...8,642,304
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3945
    regulatory pathway 2439
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1309
        transcription pathway 909
          RNA polymerase transcription pathway 343
            eukaryotic RNA polymerase transcription pathway 343
              RNA polymerase II transcription pathway 277
                RNA polymerase II transcription elongation pathway 35
paths to the root