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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr14:6,165,864...6,328,848
Ensembl chr14:5,863,961...6,024,729 		JBrowse link
G Aff4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,498,825...37,579,751 		JBrowse link
G Ccnk cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:127,090,569...127,113,191 		JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Ccnt2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr13:41,804,007...41,845,641
Ensembl chr13:39,251,573...39,292,019 		JBrowse link
G Cdc73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chr13:57,897,924...58,000,031
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:174,571,952...174,601,974
Ensembl chr 1:165,137,215...165,167,303 		JBrowse link
G Eaf1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr16:6,704,727...6,719,476
Ensembl chr16:6,698,322...6,713,071 		JBrowse link
G Eaf2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr11:77,465,585...77,509,993
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Ell elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chr16:18,877,751...18,925,449
Ensembl chr16:18,843,780...18,891,118 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:108,410,448...108,417,132 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:1,931,033...1,940,197
Ensembl chr 9:1,843,901...1,853,423 		JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr15:57,615,361...57,736,477
Ensembl chr15:51,206,031...51,327,253 		JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 8:85,080,036...85,104,471
Ensembl chr 8:76,199,099...76,223,983 		JBrowse link
G Mllt1 MLLT1, super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 9:1,818,204...1,863,091
Ensembl chr 9:1,731,080...1,775,970 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 5:107,305,008...107,561,352
Ensembl chr 5:102,260,011...102,515,361 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chr 5:65,211,632...65,244,532
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chr11:82,326,002...82,334,839
Ensembl chr11:68,817,740...68,851,885 		JBrowse link
G Nelfa negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chr14:81,033,470...81,057,546
Ensembl chr14:76,808,870...76,832,994 		JBrowse link
G Nelfb negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:28,409,045...28,425,564
Ensembl chr 3:8,010,888...8,027,403 		JBrowse link
G Nelfcd negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:183,631,968...183,643,088
Ensembl chr 3:163,213,762...163,224,884 		JBrowse link
G Nelfe negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chr20:3,981,259...3,987,016
Ensembl chr20:3,976,518...3,982,355 		JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:92,811,197...92,816,775
Ensembl chr 1:83,668,813...83,689,237 		JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:47,706,799...47,913,295 		JBrowse link
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) ISO RGD PMID:20060942 RGD:9588246 NCBI chr 3:127,113,171...127,172,761
Ensembl chr 3:106,659,308...106,718,970 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chr 8:63,999,669...64,016,959
Ensembl chr 8:55,103,545...55,120,813 		JBrowse link
G Ssrp1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:70,118,655...70,134,482 		JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr15:27,341,196...27,378,314
Ensembl chr15:24,866,489...24,904,846 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr10:73,036,560...73,042,821
Ensembl chr10:72,539,382...72,545,831 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 1:92,714,276...92,745,489
Ensembl chr 1:83,586,718...83,616,892 		JBrowse link
G Tcea1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 5:19,414,351...19,466,629
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745 		JBrowse link
G Tcea2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:189,173,756...189,181,633
Ensembl chr 3:168,796,331...168,804,116 		JBrowse link
G Tcea3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 5:153,760,401...153,792,934
Ensembl chr 5:148,476,941...148,509,448 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3866
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        transcription pathway 1059
          RNA polymerase transcription pathway 387
            eukaryotic RNA polymerase transcription pathway 387
              RNA polymerase II transcription pathway 318
                RNA polymerase II transcription elongation pathway 35
paths to the root