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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 8:131,728,819...131,924,814
Ensembl chr 8:131,728,873...131,924,819 		JBrowse link
G AFF4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 2:135,196,067...135,283,931
Ensembl chr 2:135,200,076...135,283,675 		JBrowse link
G CCNK cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chr 7:120,487,140...120,514,223
Ensembl chr 7:120,487,206...120,514,014 		JBrowse link
G CCNT1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 5:14,768,423...14,808,424
Ensembl chr 5:14,768,426...14,807,001 		JBrowse link
G CCNT2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr15:16,974,364...17,021,293
Ensembl chr15:16,974,038...17,021,298 		JBrowse link
G CDC73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chr10:575,075...667,618
Ensembl chr10:575,075...667,432 		JBrowse link
G CDK9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 1:268,277,083...268,280,493
Ensembl chr 1:268,276,841...268,281,052 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 2:48,700,629...48,729,480
Ensembl chr 2:48,700,643...48,729,516 		JBrowse link
G EAF1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr13:2,654,829...2,671,140
Ensembl chr13:2,654,630...2,671,132 		JBrowse link
G EAF2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr13:138,632,541...138,681,607
Ensembl chr13:138,648,270...138,681,613 		JBrowse link
G ELL elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chr 2:59,277,164...59,359,986
Ensembl chr 2:59,277,184...59,359,990 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 2:102,518,605...102,591,416
Ensembl chr 2:102,518,608...102,591,394 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 1:127,781,357...127,784,803
Ensembl chr 1:127,781,403...127,784,843 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 2:72,687,612...72,698,274
Ensembl chr 2:72,687,790...72,698,270 		JBrowse link
G GTF2F2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr11:21,987,410...22,144,921
Ensembl chr11:21,983,832...22,144,954 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:119,804,992...119,842,343
Ensembl chr 1:119,805,006...119,859,434 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 2:72,780,950...72,847,694
Ensembl chr 2:72,781,121...72,847,685 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 1:202,317,458...202,604,308
Ensembl chr 1:202,318,929...202,607,058 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chr 1:239,492,573...239,543,925
Ensembl chr 1:239,492,721...239,535,825 		JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chr13:133,177,209...133,192,935
Ensembl chr13:133,178,166...133,192,923 		JBrowse link
G NELFA negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chr 8:1,018,443...1,039,091
Ensembl chr 8:1,018,453...1,039,134 		JBrowse link
G NELFB negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735
G NELFCD negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chr17:59,129,055...59,141,499
Ensembl chr17:59,129,076...59,141,499 		JBrowse link
G NELFE negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chr 7:24,040,525...24,046,932
Ensembl chr 7:24,040,525...24,047,025 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 6:48,046,487...48,053,631
Ensembl chr 6:48,046,502...48,052,038 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chr 1:56,852,864...57,061,985
Ensembl chr 1:56,852,866...57,061,972 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:129,886,798...129,942,845
Ensembl chr 1:129,886,800...129,943,181 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chr 7:47,641,103...47,661,353
Ensembl chr 7:47,641,162...47,659,866 		JBrowse link
G SSRP1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 2:13,619,666...13,629,233
Ensembl chr 2:13,619,716...13,629,227 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 7:77,780,968...77,814,519
Ensembl chr 7:77,781,316...77,814,505 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr12:34,622,775...34,629,681
Ensembl chr12:34,619,729...34,629,646 		JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:48,095,001...48,125,120
Ensembl chr 6:48,095,041...48,125,119 		JBrowse link
G TCEA1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 4:77,109,555...77,138,324
Ensembl chr 4:77,109,594...77,138,320 		JBrowse link
G TCEA2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr17:62,866,594...62,888,790
Ensembl chr17:62,866,377...62,888,787 		JBrowse link
G TCEA3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:81,267,351...81,304,902
Ensembl chr 6:81,267,359...81,304,602 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4044
    regulatory pathway 2489
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1328
        transcription pathway 923
          RNA polymerase transcription pathway 349
            eukaryotic RNA polymerase transcription pathway 349
              RNA polymerase II transcription pathway 280
                RNA polymerase II transcription elongation pathway 35
paths to the root