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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter

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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624872:3,486,242...3,656,089
Ensembl chrNW_004624872:3,486,135...3,651,098 		JBrowse link
G Aff4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624733:39,126,483...39,226,969
Ensembl chrNW_004624733:39,123,575...39,221,424 		JBrowse link
G Ccnk cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624734:4,366,884...4,392,934
Ensembl chrNW_004624734:4,367,396...4,383,419 		JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624816:3,396,740...3,445,976
Ensembl chrNW_004624816:3,421,709...3,442,170 		JBrowse link
G Ccnt2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624732:34,307,124...34,357,354 JBrowse link
G Cdc73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624814:298,015...460,314
Ensembl chrNW_004624814:299,444...460,391 		JBrowse link
G Cdk9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624760:7,760,474...7,765,711 JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624766:2,823,561...2,851,742
Ensembl chrNW_004624766:2,823,229...2,851,742 		JBrowse link
G Eaf1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624822:5,240,423...5,253,762
Ensembl chrNW_004624822:5,239,964...5,253,810 		JBrowse link
G Eaf2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624912:112,793...168,553
Ensembl chrNW_004624912:112,843...168,553 		JBrowse link
G Ell elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624908:1,665,407...1,709,509
Ensembl chrNW_004624908:1,666,647...1,709,425 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624743:14,515,727...14,583,805 JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624804:10,784,575...10,789,838
Ensembl chrNW_004624804:10,786,900...10,789,766 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624828:3,512,990...3,521,848
Ensembl chrNW_004624828:3,513,027...3,521,650 		JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624748:9,703,846...9,863,320
Ensembl chrNW_004624748:9,703,846...9,863,300 		JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624731:8,467,914...8,485,978
Ensembl chrNW_004624731:8,467,877...8,485,851 		JBrowse link
G Mllt1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624828:4,055,244...4,110,246
Ensembl chrNW_004624828:4,093,502...4,110,350 		JBrowse link
G Mllt3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004624736:24,298,750...24,586,185 JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004624825:3,166,895...3,206,444
Ensembl chrNW_004624825:3,164,700...3,206,241 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004624730:61,925,831...61,931,451
Ensembl chrNW_004624730:61,925,831...61,931,385 		JBrowse link
G Nelfa negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624755:25,498,336...25,508,753
Ensembl chrNW_004624755:25,498,431...25,508,753 		JBrowse link
G Nelfb negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624760:692,735...703,571
Ensembl chrNW_004624760:692,735...705,328 		JBrowse link
G Nelfcd negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624741:25,267,334...25,280,844
Ensembl chrNW_004624741:25,267,359...25,280,844 		JBrowse link
G Nelfe negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624754:24,300,012...24,310,777
Ensembl chrNW_004624754:24,300,602...24,310,671 		JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624794:12,719,819...12,725,109
Ensembl chrNW_004624794:12,719,861...12,725,122 		JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004624799:5,225,293...5,553,957
Ensembl chrNW_004624799:5,225,264...5,554,168 		JBrowse link
G Rtf1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624804:8,588,751...8,649,180 JBrowse link
G Skic8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004624894:2,575,870...2,592,667
Ensembl chrNW_004624894:2,575,916...2,592,666 		JBrowse link
G Ssrp1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624864:3,253,639...3,262,105 JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624825:7,366,448...7,410,847
Ensembl chrNW_004624825:7,367,325...7,410,823 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624871:183,495...189,838
Ensembl chrNW_004624871:184,298...189,798 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624794:12,766,734...12,791,590
Ensembl chrNW_004624794:12,766,806...12,804,611 		JBrowse link
G Tcea1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624735:1,637,453...1,700,839
Ensembl chrNW_004624735:1,637,465...1,704,154 		JBrowse link
G Tcea2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624741:29,691,983...29,699,383
Ensembl chrNW_004624741:29,692,006...29,699,383 		JBrowse link
G Tcea3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004624764:8,020,241...8,072,052 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3917
    regulatory pathway 2426
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1306
        transcription pathway 907
          RNA polymerase transcription pathway 348
            eukaryotic RNA polymerase transcription pathway 348
              RNA polymerase II transcription pathway 279
                RNA polymerase II transcription elongation pathway 35
paths to the root