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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF1 ALF transcription elongation factor 1 TAS RGD PMID:22895430 RGD:9681740 NCBI chr 4:86,935,011...87,141,039
Ensembl chr 4:86,935,002...87,141,039 		JBrowse link
G AFF4 ALF transcription elongation factor 4 TAS RGD PMID:22895430 RGD:9681740 NCBI chr 5:132,875,395...132,963,634
Ensembl chr 5:132,875,395...132,963,634 		JBrowse link
G CCNK cyclin K TAS RGD PMID:24050178 RGD:9681735 NCBI chr14:99,481,409...99,512,440
Ensembl chr14:99,481,169...99,535,044 		JBrowse link
G CCNT1 cyclin T1 TAS RGD PMID:24050178 RGD:9681735 NCBI chr12:48,688,458...48,716,707
Ensembl chr12:48,688,458...48,716,998 		JBrowse link
G CCNT2 cyclin T2 TAS RGD PMID:24050178 RGD:9681735 NCBI chr 2:134,918,822...134,959,342
Ensembl chr 2:134,918,235...134,959,342 		JBrowse link
G CDC73 cell division cycle 73 TAS RGD PMID:20060942 RGD:9588246 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CDK9 cyclin dependent kinase 9 TAS RGD PMID:24050178 RGD:9681735 NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component TAS RGD PMID:20060942 RGD:9588246 NCBI chr11:10,751,246...10,779,746
Ensembl chr11:10,751,018...10,801,625 		JBrowse link
G EAF1 ELL associated factor 1 TAS RGD PMID:22895430 RGD:9681740 NCBI chr 3:15,427,598...15,442,613
Ensembl chr 3:15,427,598...15,450,635 		JBrowse link
G EAF2 ELL associated factor 2 TAS RGD PMID:22895430 RGD:9681740 NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526 		JBrowse link
G ELL elongation factor for RNA polymerase II TAS RGD PMID:22895430 RGD:9681740 NCBI chr19:18,442,663...18,522,070
Ensembl chr19:18,442,663...18,522,116 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 TAS RGD PMID:22895430 RGD:9681740 NCBI chr 5:95,885,098...95,961,851
Ensembl chr 5:95,885,098...95,961,851 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 TAS RGD PMID:22895430 RGD:9681740 NCBI chr15:43,772,620...43,776,966
Ensembl chr15:43,772,605...43,777,315 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 TAS RGD PMID:24050178 RGD:9681735 NCBI chr19:6,379,572...6,393,164
Ensembl chr19:6,379,572...6,393,981 		JBrowse link
G GTF2F2 general transcription factor IIF subunit 2 TAS RGD PMID:24050178 RGD:9681735 NCBI chr13:45,120,510...45,284,893
Ensembl chr13:45,120,510...45,284,893 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component TAS RGD PMID:20060942 RGD:9588246 NCBI chr15:51,938,025...51,971,778
Ensembl chr15:51,938,025...51,971,778 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit TAS RGD PMID:22895430 RGD:9681740 NCBI chr19:6,210,381...6,279,975
Ensembl chr19:6,210,381...6,279,975 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit TAS RGD PMID:22895430 RGD:9681740 NCBI chr 9:20,341,669...20,622,499
Ensembl chr 9:20,341,669...20,622,499 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 TAS RGD PMID:24354960 RGD:9684851 NCBI chr 9:97,633,821...97,673,748
Ensembl chr 9:97,633,668...97,673,748 		JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 TAS RGD PMID:24354960 RGD:9684851 NCBI chr 3:196,935,406...196,942,528
Ensembl chr 3:196,935,402...196,942,594 		JBrowse link
G NELFA negative elongation factor complex member A TAS RGD PMID:24050178 RGD:9681735 NCBI chr 4:1,982,723...2,008,974
Ensembl chr 4:1,982,717...2,041,903 		JBrowse link
G NELFB negative elongation factor complex member B TAS RGD PMID:24050178 RGD:9681735 NCBI chr 9:137,255,327...137,273,542
Ensembl chr 9:137,255,327...137,273,542 		JBrowse link
G NELFCD negative elongation factor complex member C/D TAS RGD PMID:24050178 RGD:9681735 NCBI chr20:58,981,256...58,995,113
Ensembl chr20:58,981,208...58,995,133 		JBrowse link
G NELFE negative elongation factor complex member E TAS RGD PMID:24050178 RGD:9681735 NCBI chr 6:31,952,087...31,958,971
Ensembl chr 6:31,952,087...31,959,038 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component TAS RGD PMID:20060942 RGD:9588246 NCBI chr19:39,385,629...39,391,106
Ensembl chr19:39,385,629...39,391,154 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase TAS RGD PMID:24354960 RGD:9684851 NCBI chr 6:88,609,897...88,963,618
Ensembl chr 6:88,609,897...88,963,618 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component TAS RGD PMID:20060942 RGD:9588246 NCBI chr15:41,417,095...41,483,563
Ensembl chr15:41,408,408...41,483,563 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex TAS RGD PMID:20060942 RGD:9588246 NCBI chr15:78,283,235...78,299,609
Ensembl chr15:78,277,835...78,299,703 		JBrowse link
G SSRP1 structure specific recognition protein 1 TAS RGD PMID:24050178 RGD:9681735 NCBI chr11:57,325,988...57,335,892
Ensembl chr11:57,325,986...57,335,892 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit TAS RGD PMID:24050178 RGD:9681735 NCBI chr14:21,351,476...21,384,019
Ensembl chr14:21,351,476...21,384,019 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit TAS RGD PMID:24050178 RGD:9681735 NCBI chr17:58,345,178...58,352,201
Ensembl chr17:58,345,175...58,353,093 		JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit TAS RGD PMID:24050178 RGD:9681735 NCBI chr19:39,445,582...39,476,670
Ensembl chr19:39,436,156...39,476,670 		JBrowse link
G TCEA1 transcription elongation factor A1 TAS RGD PMID:24050178 RGD:9681735 NCBI chr 8:53,966,556...54,022,448
Ensembl chr 8:53,966,552...54,022,448 		JBrowse link
G TCEA2 transcription elongation factor A2 TAS RGD PMID:24050178 RGD:9681735 NCBI chr20:64,055,596...64,072,347
Ensembl chr20:64,049,836...64,072,347 		JBrowse link
G TCEA3 transcription elongation factor A3 TAS RGD PMID:24050178 RGD:9681735 NCBI chr 1:23,380,909...23,424,748
Ensembl chr 1:23,380,909...23,424,748 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3600
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1637
        transcription pathway 1053
          RNA polymerase transcription pathway 387
            eukaryotic RNA polymerase transcription pathway 387
              RNA polymerase II transcription pathway 318
                RNA polymerase II transcription elongation pathway 35
paths to the root