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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr32:10,430,159...10,631,305
Ensembl chr32:10,430,090...10,632,172 		JBrowse link
G AFF4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chr11:21,157,790...21,218,750
Ensembl chr11:21,163,398...21,218,190 		JBrowse link
G CCNK cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chr 8:67,910,772...67,927,216
Ensembl chr 8:67,901,426...67,945,214 		JBrowse link
G CCNT1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr27:5,788,426...5,817,518
Ensembl chr27:5,788,785...5,817,043 		JBrowse link
G CCNT2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr19:37,743,442...37,787,875
Ensembl chr19:37,743,235...37,783,220 		JBrowse link
G CDC73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chr38:5,826,209...5,937,930
Ensembl chr38:5,805,916...5,938,111 		JBrowse link
G CDK9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:55,615,271...55,619,493
Ensembl chr 9:55,615,827...55,620,236 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr21:33,915,804...33,949,597
Ensembl chr21:33,915,772...33,949,103 		JBrowse link
G EAF1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr23:27,188,983...27,203,441
Ensembl chr23:27,159,751...27,203,558 		JBrowse link
G EAF2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr33:25,113,348...25,147,064
Ensembl chr33:25,112,570...25,146,692 		JBrowse link
G ELL elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chr20:44,512,665...44,592,156
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 3:13,673,653...13,746,604
Ensembl chr 3:13,673,785...13,746,316 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chr30:10,514,633...10,517,963
Ensembl chr30:10,515,045...10,517,880 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr20:53,771,201...53,780,646
Ensembl chr20:53,771,325...53,780,644 		JBrowse link
G GTF2F2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr22:5,757,445...5,904,725
Ensembl chr22:5,757,960...5,904,814 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr30:17,614,502...17,651,715
Ensembl chr30:17,598,076...17,651,290 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr20:53,844,972...53,913,753
Ensembl chr20:53,779,802...53,913,651 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr11:39,923,165...40,203,574
Ensembl chr11:39,927,517...40,203,281 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chr11:54,938,250...54,974,536
Ensembl chr11:54,938,372...54,974,547 		JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chr33:29,911,457...29,943,596
Ensembl chr33:29,912,569...29,962,175 		JBrowse link
G NELFA negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chr 3:62,147,948...62,164,039
Ensembl chr 3:62,147,948...62,164,112 		JBrowse link
G NELFB negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:48,411,725...48,425,044
Ensembl chr 9:48,408,005...48,423,308 		JBrowse link
G NELFCD negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chr24:43,685,356...43,743,239
Ensembl chr24:43,734,236...43,743,233 		JBrowse link
G NELFE negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chr12:1,406,411...1,412,387
Ensembl chr12:1,406,271...1,412,324 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:113,828,219...113,832,747
Ensembl chr 1:113,828,007...113,832,735 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chr12:47,944,600...48,306,789
Ensembl chr12:47,946,561...48,275,969 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr30:8,468,001...8,524,712
Ensembl chr30:8,467,761...8,522,874 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chr 3:58,403,146...58,418,782
Ensembl chr 3:58,403,146...58,418,782 		JBrowse link
G SSRP1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr18:38,802,673...38,812,134
Ensembl chr18:38,802,619...38,812,131 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr15:18,387,624...18,429,553
Ensembl chr15:18,388,512...18,429,553 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:32,990,060...32,996,023
Ensembl chr 9:32,990,061...33,191,176 		JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr 1:113,759,419...113,788,490
Ensembl chr 1:113,759,423...113,788,447 		JBrowse link
G TCEA1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr29:5,616,936...5,655,341
Ensembl chr29:5,616,961...5,697,284 		JBrowse link
G TCEA2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr24:47,508,161...47,512,399
Ensembl chr24:47,508,136...47,537,250 		JBrowse link
G TCEA3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 2:75,998,154...76,040,461
Ensembl chr 2:75,998,214...76,040,413 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    regulatory pathway 2499
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1332
        transcription pathway 926
          RNA polymerase transcription pathway 349
            eukaryotic RNA polymerase transcription pathway 349
              RNA polymerase II transcription pathway 280
                RNA polymerase II transcription elongation pathway 35
paths to the root