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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955474:2,748,438...2,899,094
Ensembl chrNW_004955474:2,751,809...2,896,311
JBrowse link
G Aff4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955408:4,247,730...4,305,194
Ensembl chrNW_004955408:4,248,563...4,305,194
JBrowse link
G Ccnk cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955438:20,826,818...20,850,496
Ensembl chrNW_004955438:20,835,825...20,849,999
JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955500:7,580,625...7,606,913
Ensembl chrNW_004955500:7,580,625...7,606,913
JBrowse link
G Ccnt2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955440:2,424,976...2,468,388
Ensembl chrNW_004955440:2,424,978...2,470,811
JBrowse link
G Cdc73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955406:30,533,919...30,665,812
Ensembl chrNW_004955406:30,533,060...30,665,812
JBrowse link
G Cdk9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955419:874,959...883,160
Ensembl chrNW_004955419:873,289...883,160
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955414:26,347,508...26,373,726
Ensembl chrNW_004955414:26,347,508...26,373,785
JBrowse link
G Eaf1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955430:1,933,290...1,946,900
Ensembl chrNW_004955430:1,933,290...1,947,932
JBrowse link
G Eaf2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955427:21,171,900...21,204,138
Ensembl chrNW_004955427:21,172,009...21,204,051
JBrowse link
G Ell elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955524:3,054,296...3,094,125
Ensembl chrNW_004955524:3,054,292...3,092,973
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955418:16,615,340...16,686,632
Ensembl chrNW_004955418:16,614,543...16,687,698
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955416:10,223,213...10,226,978
Ensembl chrNW_004955416:10,198,508...10,226,120
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955495:3,208,334...3,217,460
Ensembl chrNW_004955495:3,208,733...3,217,163
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955518:2,912,259...3,064,298
Ensembl chrNW_004955518:2,912,259...3,064,298
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955409:2,711,475...2,727,879
Ensembl chrNW_004955409:2,711,564...2,727,755
JBrowse link
G Mllt1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955495:3,289,644...3,336,455
Ensembl chrNW_004955495:3,289,641...3,336,509
JBrowse link
G Mllt3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chrNW_004955434:22,594,681...22,873,826
Ensembl chrNW_004955434:22,594,681...22,873,826
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004955419:27,778,300...27,819,878
Ensembl chrNW_004955419:27,778,300...27,819,878
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004955420:12,979,368...12,992,500
Ensembl chrNW_004955420:12,979,368...12,992,500
JBrowse link
G Nelfa negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955514:1,162,993...1,173,278
Ensembl chrNW_004955514:1,162,993...1,173,278
JBrowse link
G Nelfb negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955513:5,248,190...5,261,018
Ensembl chrNW_004955513:5,248,190...5,262,044
JBrowse link
G Nelfcd negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955445:597,826...610,134
Ensembl chrNW_004955445:597,826...610,134
JBrowse link
G Nelfe negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955437:467,018...473,084
Ensembl chrNW_004955437:466,690...473,084
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955468:166,477...172,200 JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chrNW_004955411:15,486,532...15,766,880
Ensembl chrNW_004955411:15,486,303...15,766,864
JBrowse link
G Rtf1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955416:8,237,439...8,293,802
Ensembl chrNW_004955416:8,237,439...8,293,802
JBrowse link
G Skic8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chrNW_004955450:771,646...788,895
Ensembl chrNW_004955450:770,750...789,485
JBrowse link
G Ssrp1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955511:2,378,720...2,388,201
Ensembl chrNW_004955511:2,378,652...2,388,198
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955550:2,074,646...2,114,634
Ensembl chrNW_004955550:2,074,941...2,114,528
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955451:4,682,308...4,688,008
Ensembl chrNW_004955451:4,682,311...4,688,008
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955468:95,997...123,005
Ensembl chrNW_004955468:95,181...123,147
JBrowse link
G Tcea1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955454:13,312,823...13,347,128
Ensembl chrNW_004955454:13,312,823...13,347,129
JBrowse link
G Tcea2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955528:186,642...194,058
Ensembl chrNW_004955528:186,642...194,058
JBrowse link
G Tcea3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chrNW_004955452:3,384,424...3,434,182 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3924
    regulatory pathway 2432
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1319
        transcription pathway 913
          RNA polymerase transcription pathway 346
            eukaryotic RNA polymerase transcription pathway 346
              RNA polymerase II transcription pathway 277
                RNA polymerase II transcription elongation pathway 35
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