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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:RNA polymerase II transcription elongation pathway
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Accession:PW:0001331 term browser browse the term
Definition:RNA polymerase II transcription elongation commences when the nascent transcript reaches about 25 residues. Some general transcription factors are released and the RNA polymerase II carries out elongation of the pre-mRNA transcript and proofreading. Various regulators control early elongation, proximal promoter pausing and full elongation proceedings. Nascent mRNA processing, splicing and alternative splicing are co-occurring.
Synonyms:related_synonym: RNA Polymerase II Transcription Elongation;   transcription elongation by RNA polymerase II promoter


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RNA polymerase II transcription elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF1 ALF transcription elongation factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 4:79,197,196...79,443,485
Ensembl chr 4:89,969,675...90,166,160 		JBrowse link
G AFF4 ALF transcription elongation factor 4 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 5:128,292,700...128,374,511
Ensembl chr 5:134,457,398...134,532,625 		JBrowse link
G CCNK cyclin K ISO RGD PMID:24050178 RGD:9681735 NCBI chr14:80,105,372...80,136,511
Ensembl chr14:99,438,814...99,480,842 		JBrowse link
G CCNT1 cyclin T1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr12:40,028,334...40,057,393
Ensembl chr12:40,906,907...40,935,392 		JBrowse link
G CCNT2 cyclin T2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr2B:24,903,389...24,943,122
Ensembl chr2B:138,994,868...139,035,301 		JBrowse link
G CDC73 cell division cycle 73 ISO RGD PMID:20060942 RGD:9588246 NCBI chr 1:168,581,730...168,710,915
Ensembl chr 1:172,875,365...173,004,934 		JBrowse link
G CDK9 cyclin dependent kinase 9 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:98,905,468...98,909,923
Ensembl chr 9:127,580,862...127,584,935 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr11:10,884,353...10,913,246
Ensembl chr11:10,610,892...10,639,808 		JBrowse link
G EAF1 ELL associated factor 1 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 3:15,353,459...15,368,579
Ensembl chr 3:15,689,745...15,705,300 		JBrowse link
G EAF2 ELL associated factor 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 3:118,936,685...118,996,051
Ensembl chr 3:125,844,338...125,895,416 		JBrowse link
G ELL elongation factor for RNA polymerase II ISO RGD PMID:22895430 RGD:9681740 NCBI chr19:17,923,035...17,999,842
Ensembl chr19:18,894,054...18,969,923 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 ISO RGD PMID:22895430 RGD:9681740 NCBI chr 5:19,387,443...19,464,150
Ensembl chr 5:19,533,442...19,610,079 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 ISO RGD PMID:22895430 RGD:9681740 NCBI chr15:22,732,742...22,737,522
Ensembl chr15:40,821,759...40,827,070 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr19:5,401,090...5,414,142
Ensembl chr19:6,323,780...6,336,215 		JBrowse link
G GTF2F2 general transcription factor IIF subunit 2 ISO RGD PMID:24050178 RGD:9681735 NCBI chr13:26,286,305...26,452,302
Ensembl chr 3:197,619,461...197,784,798 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr15:30,879,431...30,913,361
Ensembl chr15:49,208,132...49,241,055 		JBrowse link
G MLLT1 MLLT1 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr19:5,231,481...5,301,160
Ensembl chr19:6,156,365...6,216,779 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit ISO RGD PMID:22895430 RGD:9681740 NCBI chr 9:20,140,160...20,417,327
Ensembl chr 9:20,800,393...21,073,046 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 ISO RGD PMID:24354960 RGD:9684851 NCBI chr 9:68,724,176...68,764,423
Ensembl chr 9:96,845,422...96,885,624 		JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 ISO RGD PMID:24354960 RGD:9684851 NCBI chr 3:194,277,280...194,284,456
Ensembl chr 3:204,214,282...204,221,294 		JBrowse link
G NELFA negative elongation factor complex member A ISO RGD PMID:24050178 RGD:9681735 NCBI chr 4:2,119,699...2,147,618
Ensembl chr 4:2,027,939...2,054,669 		JBrowse link
G NELFB negative elongation factor complex member B ISO RGD PMID:24050178 RGD:9681735 NCBI chr 9:108,314,535...108,333,050
Ensembl chr 9:137,278,964...137,301,751 		JBrowse link
G NELFCD negative elongation factor complex member C/D ISO RGD PMID:24050178 RGD:9681735 NCBI chr20:55,332,309...55,346,167
Ensembl chr20:56,693,685...56,706,458 		JBrowse link
G NELFE negative elongation factor complex member E ISO RGD PMID:24050178 RGD:9681735 NCBI chr 6:31,612,924...31,619,732
Ensembl chr 6:32,499,540...32,506,382 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr19:36,484,099...36,489,364
Ensembl chr19:45,031,819...45,037,169 		JBrowse link
G RNGTT RNA guanylyltransferase and 5'-phosphatase ISO RGD PMID:24354960 RGD:9684851 NCBI chr 6:86,490,725...86,841,421
Ensembl chr 6:89,761,712...90,118,184 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component ISO RGD PMID:20060942 RGD:9588246 NCBI chr15:20,355,927...20,424,153
Ensembl chr15:38,599,163...38,662,100 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex ISO RGD PMID:20060942 RGD:9588246 NCBI chr15:57,204,199...57,229,052
Ensembl chr15:76,175,131...76,194,368 		JBrowse link
G SSRP1 structure specific recognition protein 1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr11:52,567,420...52,577,324
Ensembl chr 3:160,057,285...160,068,177 		JBrowse link
G SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr14:2,169,169...2,201,911
Ensembl chr14:20,247,325...20,280,074 		JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr17:52,420,503...52,427,514 JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit ISO RGD PMID:24050178 RGD:9681735 NCBI chr19:36,543,998...36,575,161
Ensembl chr19:45,092,075...45,122,335 		JBrowse link
G TCEA1 transcription elongation factor A1 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 8:50,393,553...50,449,698
Ensembl chr 8:47,770,661...47,825,804 		JBrowse link
G TCEA2 transcription elongation factor A2 ISO RGD PMID:24050178 RGD:9681735 Ensembl chr20:61,976,869...61,986,592 JBrowse link
G TCEA3 transcription elongation factor A3 ISO RGD PMID:24050178 RGD:9681735 NCBI chr 1:22,573,050...22,617,426
Ensembl chr 1:23,560,258...23,602,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4064
    regulatory pathway 2507
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1338
        transcription pathway 927
          RNA polymerase transcription pathway 348
            eukaryotic RNA polymerase transcription pathway 348
              RNA polymerase II transcription pathway 279
                RNA polymerase II transcription elongation pathway 35
paths to the root