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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:de novo nicotinamide adenine dinucleotide biosynthetic pathway
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Accession:PW:0001276 term browser browse the term
Definition:Those metabolic reactions involved in the de novo synthesis of nicotinamide adenine dinucleotide (NAD), downstream of kynurenine metabolism of tryptophan degradation.
Synonyms:exact_synonym: de novo NAD biosynthetic pathway
 related_synonym: 'de novo' NAD biosynthetic process


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de novo nicotinamide adenine dinucleotide biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NADSYN1 NAD synthetase 1 TAS RGD PMID:20007326 RGD:11099972 NCBI chr11:71,453,203...71,501,816
Ensembl chr11:71,453,109...71,524,107 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 TAS RGD PMID:20007326 RGD:11099972 NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501 		JBrowse link
G NMNAT2 nicotinamide nucleotide adenylyltransferase 2 TAS RGD PMID:20007326 RGD:11099972 NCBI chr 1:183,248,237...183,418,380
Ensembl chr 1:183,248,237...183,418,380 		JBrowse link
G NMNAT3 nicotinamide nucleotide adenylyltransferase 3 TAS RGD PMID:20007326 RGD:11099972 NCBI chr 3:139,560,180...139,678,050
Ensembl chr 3:139,560,180...139,678,017 		JBrowse link
G QPRT quinolinate phosphoribosyltransferase TAS RGD PMID:20007326 RGD:11099972 NCBI chr16:29,679,008...29,698,699
Ensembl chr16:29,663,279...29,698,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    classic metabolic pathway 1802
      metabolic pathway of cofactors, vitamins, nutrients 370
        nicotinamide adenine dinucleotide metabolic pathway 60
          nicotinamide adenine dinucleotide biosynthetic pathway 9
            de novo nicotinamide adenine dinucleotide biosynthetic pathway 5
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