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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:de novo nicotinamide adenine dinucleotide biosynthetic pathway
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Accession:PW:0001276 term browser browse the term
Definition:Those metabolic reactions involved in the de novo synthesis of nicotinamide adenine dinucleotide (NAD), downstream of kynurenine metabolism of tryptophan degradation.
Synonyms:exact_synonym: de novo NAD biosynthetic pathway
 related_synonym: 'de novo' NAD biosynthetic process


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de novo nicotinamide adenine dinucleotide biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NADSYN1 NAD synthetase 1 ISO RGD PMID:20007326 RGD:11099972 NCBI chr11:66,464,320...66,537,649
Ensembl chr11:69,735,871...69,788,953 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 ISO RGD PMID:20007326 RGD:11099972 NCBI chr 1:8,712,798...8,753,027
Ensembl chr 1:9,942,491...9,982,364 		JBrowse link
G NMNAT2 nicotinamide nucleotide adenylyltransferase 2 ISO RGD PMID:20007326 RGD:11099972 NCBI chr 1:158,768,949...158,948,711
Ensembl chr 1:162,929,609...163,105,524 		JBrowse link
G NMNAT3 nicotinamide nucleotide adenylyltransferase 3 ISO RGD PMID:20007326 RGD:11099972 NCBI chr 3:136,594,825...136,715,437 JBrowse link
G QPRT quinolinate phosphoribosyltransferase ISO RGD PMID:20007326 RGD:11099972 Ensembl chr16:30,049,806...30,070,469 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4069
    classic metabolic pathway 1016
      metabolic pathway of cofactors, vitamins, nutrients 239
        nicotinamide adenine dinucleotide metabolic pathway 59
          nicotinamide adenine dinucleotide biosynthetic pathway 9
            de novo nicotinamide adenine dinucleotide biosynthetic pathway 5
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