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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA polymerase II transcription initiation pathway
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Accession:PW:0001274 term browser browse the term
Definition:RNA polymerase II and a set of general and specific transcription factors assemble as a large pre-initiation complex which undergoes a series of transformations before transcription proceeds. Promoter recognition and subsequent initiation of transcription are dependent upon the presence of these transcription factors. Activators and repressors impact upon transcription at these early stages.


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RNA polymerase II transcription initiation pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn7 ataxin 7 JBrowse link 15 12,421,432 12,569,649 RGD:9681728
G Atxn7l3 ataxin 7-like 3 JBrowse link 10 90,234,749 90,241,757 RGD:9681728
G Ccnh cyclin H JBrowse link 2 13,593,100 13,613,910 RGD:9681726
G Cdk7 cyclin-dependent kinase 7 JBrowse link 2 30,710,642 30,735,522 RGD:9681726
G Dr1 down-regulator of transcription 1 JBrowse link 14 2,463,651 2,475,004 RGD:9681728
G Eny2 ENY2, transcription and export complex 2 subunit JBrowse link 7 83,348,656 83,358,430 RGD:9681728
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:9681726
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit JBrowse link 18 25,037,668 25,068,380 RGD:9681726
G Ercc5 ERCC excision repair 5, endonuclease JBrowse link 9 50,928,847 50,970,962 RGD:9681726
G Gtf2a1 general transcription factor 2A subunit 1 JBrowse link 6 115,321,110 115,352,659 RGD:9681721
G Gtf2a2 general transcription factor 2A subunit 2 JBrowse link 8 76,422,341 76,435,587 RGD:9681721
G Gtf2b general transcription factor IIB JBrowse link 2 248,709,433 248,727,741 RGD:9681721
G Gtf2e1 general transcription factor IIE subunit 1 JBrowse link 11 66,078,786 66,111,394 RGD:9681721
G Gtf2e2 general transcription factor IIE subunit 2 JBrowse link 16 62,113,846 62,164,339 RGD:9681721
G Gtf2f1 general transcription factor IIF subunit 1 JBrowse link 9 10,032,806 10,042,392 RGD:9681721
G Gtf2f2 general transcription factor IIF subunit 2 JBrowse link 15 57,942,057 58,068,892 RGD:9681721
G Gtf2h1 general transcription factor IIH subunit 1 JBrowse link 1 102,849,618 102,877,939 RGD:9681726
G Gtf2h2 general transcription factor IIH subunit 2 JBrowse link 2 30,494,718 30,522,716 RGD:9681726
G Gtf2h3 general transcription factor IIH subunit 3 JBrowse link 12 37,427,556 37,444,027 RGD:9681726
G Gtf2h4 general transcription factor 2H subunit 4 JBrowse link 20 3,582,688 3,588,373 RGD:9681726
G Gtf2h5 general transcription factor IIH subunit 5 JBrowse link 1 46,978,345 46,985,032 RGD:9681726
G Hcfc2 host cell factor C2 JBrowse link 7 27,107,931 27,136,658 RGD:9681728
G Kat14 lysine acetyltransferase 14 JBrowse link 3 138,508,899 138,549,437 RGD:9681728
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:9681728
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:9681728
G Mbip MAP3K12 binding inhibitory protein 1 JBrowse link 6 77,226,439 77,243,696 RGD:9681728
G Mnat1 MNAT1 component of CDK activating kinase JBrowse link 6 95,995,341 96,153,331 RGD:9681726
G Pole3 DNA polymerase epsilon 3, accessory subunit JBrowse link 5 78,380,813 78,384,047 RGD:9681728
G Sgf29 SAGA complex associated factor 29 JBrowse link 1 198,066,974 198,100,494 RGD:9681728
G Supt20h SPT20 homolog, SAGA complex component JBrowse link 2 143,892,609 143,925,733 RGD:9681728
G Supt3h SPT3 homolog, SAGA and STAGA complex component JBrowse link 9 18,249,565 18,604,814 RGD:9681728
G Supt7l SPT7 like, STAGA complex subunit gamma JBrowse link 6 26,241,672 26,251,810 RGD:9681728
G Tada1 transcriptional adaptor 1 JBrowse link 13 84,588,587 84,602,542 RGD:9681728
G Tada2a transcriptional adaptor 2A JBrowse link 10 71,393,701 71,441,435 RGD:9681728
G Tada2b transcriptional adaptor 2B JBrowse link 14 79,446,057 79,457,341 RGD:9681728
G Tada3 transcriptional adaptor 3 JBrowse link 4 145,318,417 145,330,291 RGD:9681728
G Taf1 TATA-box binding protein associated factor 1 JBrowse link X 71,412,291 71,486,456 RGD:9681723
G Taf10 TATA-box binding protein associated factor 10 JBrowse link 1 170,585,160 170,586,428 RGD:9681723
RGD:9681728
G Taf11 TATA-box binding protein associated factor 11 JBrowse link 20 7,476,648 7,484,417 RGD:9681723
G Taf12 TATA-box binding protein associated factor 12 JBrowse link 5 150,459,701 150,476,521 RGD:9681723
RGD:9681728
G Taf13 TATA-box binding protein associated factor 13 JBrowse link 2 211,359,623 211,370,285 RGD:9681723
G Taf15 TATA-box binding protein associated factor 15 JBrowse link 10 70,689,863 70,721,892 RGD:9681723
G Taf2 TATA-box binding protein associated factor 2 JBrowse link 7 94,698,987 94,755,924 RGD:9681723
G Taf3 TATA-box binding protein associated factor 3 JBrowse link 17 72,240,785 72,393,448 RGD:9681723
G Taf4 TATA-box binding protein associated factor 4 JBrowse link 3 175,300,842 175,364,655 RGD:9681723
G Taf5 TATA-box binding protein associated factor 5 JBrowse link 1 266,844,480 266,859,965 RGD:9681723
G Taf5l TATA-box binding protein associated factor 5 like JBrowse link 19 56,781,854 56,801,005 RGD:9681728
G Taf6 TATA-box binding protein associated factor 6 JBrowse link 12 19,320,269 19,328,706 RGD:9681723
G Taf6l TATA-box binding protein associated factor 6 like JBrowse link 1 224,974,238 224,986,819 RGD:9681728
G Taf7 TATA-box binding protein associated factor 7 JBrowse link 18 30,779,149 30,781,297 RGD:9681723
G Taf8 TATA-box binding protein associated factor 8 JBrowse link 9 15,513,048 15,532,992 RGD:9681723
G Taf9 TATA-box binding protein associated factor 9 JBrowse link 2 30,664,407 30,668,414 RGD:9681723
RGD:9681728
G Tbp TATA box binding protein JBrowse link 1 57,491,381 57,509,335 RGD:9681721
RGD:9681723
G Trrap transformation/transcription domain-associated protein JBrowse link 12 11,537,950 11,627,563 RGD:9681728
G Usp22 ubiquitin specific peptidase 22 JBrowse link 10 47,429,201 47,453,298 RGD:9681728
G Wdr5 WD repeat domain 5 JBrowse link 3 6,061,892 6,080,724 RGD:9681728
G Yeats2 YEATS domain containing 2 JBrowse link 11 84,330,064 84,595,296 RGD:9681728
G Zzz3 zinc finger, ZZ-type containing 3 JBrowse link 2 257,602,924 257,671,783 RGD:9681728

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Term Annotations click to browse term
  pathway 6064
    regulatory pathway 3843
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1723
        transcription pathway 1049
          RNA polymerase transcription pathway 375
            eukaryotic RNA polymerase transcription pathway 375
              RNA polymerase II transcription pathway 308
                RNA polymerase II transcription initiation pathway 58
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.