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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:codeine and morphine pharmacokinetics pathway
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Accession:PW:0001245 term browser browse the term
Definition:The pathway of processing - absorption, distribution, metabolism or elimination - of codeine and morphine, a class of drug opiates used as pain relievers. Genetic variations can result in changes in the availability of the drug.
Synonyms:related_synonym: SMP:00621;   SMP:00622


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codeine and morphine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO SMPDB SMP:00621 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO SMPDB SMP:00621 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00622 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00622 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00622 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00622 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hyou1 hypoxia up-regulated 1 ISO SMPDB SMP:00622 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO SMPDB SMP:00621 SMP:00622 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 ISO SMPDB SMP:00622 NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 ISO SMPDB SMP:00622 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 ISO SMPDB SMP:00622 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO SMPDB SMP:00622 NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 ISO SMPDB SMP:00622 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 ISO SMPDB SMP:00622 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 ISO SMPDB SMP:00622 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 ISO SMPDB SMP:00622 NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 ISO SMPDB SMP:00621 SMP:00622 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      nervous system drug pathway 183
        analgesic and/or antipyretic drug pathway 97
          opioid drug pathway 55
            codeine and morphine drug pathway 46
              codeine and morphine pharmacokinetics pathway 17
paths to the root