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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:prostanoid biosynthetic pathway
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Accession:PW:0001243 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of prostanoids, a class of eicosanoids that includes several families and which has important roles in the immune and vascular systems.
Synonyms:related_synonym: prostanoid biosynthetic process
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prostanoid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
prostacyclin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgis prostaglandin I2 (prostacyclin) synthase ISO RGD PMID:22679221 PMID:10536678 PMID:10073980 RGD:8552712, RGD:401959739, RGD:401960092 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
prostaglandin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1, member A1 ISO RGD PMID:23747692 RGD:8552778 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO RGD PMID:23747692 RGD:8552778 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413 		JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 ISO RGD PMID:12432932 RGD:8552774 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO RGD PMID:12432932 RGD:8552774 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 6:65,094,019...65,121,960
Ensembl chr 6:65,094,277...65,121,892 		JBrowse link
G Prxl2b peroxiredoxin like 2B IDA RGD PMID:18006499 RGD:8552775 NCBI chr 4:154,980,884...154,983,522
Ensembl chr 4:154,979,961...154,983,592 		JBrowse link
G Ptgds prostaglandin D2 synthase (brain) ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058 		JBrowse link
G Ptges prostaglandin E synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875 		JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 2:32,285,902...32,292,752
Ensembl chr 2:32,285,908...32,295,784 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr10:127,894,851...127,913,123
Ensembl chr10:127,894,823...127,913,141 		JBrowse link
thromboxane biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbxas1 thromboxane A synthase 1, platelet ISO RGD PMID:22679221 RGD:8552712 NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6071
    classic metabolic pathway 1858
      lipid metabolic pathway 455
        eicosanoid metabolic pathway 18
          prostanoid metabolic pathway 14
            prostanoid biosynthetic pathway 14
              prostacyclin biosynthetic pathway 1
              prostaglandin biosynthetic pathway 10
              thromboxane biosynthetic pathway 1
paths to the root