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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:prostanoid biosynthetic pathway
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Accession:PW:0001243 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of prostanoids, a class of eicosanoids that includes several families and which has important roles in the immune and vascular systems.
Synonyms:related_synonym: prostanoid biosynthetic process
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prostanoid biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
prostacyclin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgis prostaglandin I2 synthase ISO
IMP		 RGD PMID:22679221 PMID:10536678 PMID:10073980 RGD:8552712, RGD:401959739, RGD:401960092 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
prostaglandin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:23747692 RGD:8552778 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 ISO RGD PMID:23747692 RGD:8552778 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 TAS RGD PMID:12432932 RGD:8552774 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cbr1 carbonyl reductase 1 ISO RGD PMID:12432932 RGD:8552774 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Prxl2b peroxiredoxin like 2B ISO RGD PMID:18006499 RGD:8552775 NCBI chr 5:165,462,610...165,465,213 JBrowse link
G Ptgds prostaglandin D2 synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptges prostaglandin E synthase ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO RGD PMID:23063076 PMID:22679221 RGD:8552701, RGD:8552712 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
thromboxane biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbxas1 thromboxane A synthase 1 ISO RGD PMID:22679221 RGD:8552712 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        eicosanoid metabolic pathway 18
          prostanoid metabolic pathway 14
            prostanoid biosynthetic pathway 14
              prostacyclin biosynthetic pathway 1
              prostaglandin biosynthetic pathway 10
              thromboxane biosynthetic pathway 1
paths to the root