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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:kinase mediated signaling pathway
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Accession:PW:0001193 term browser browse the term
Definition:Kinases are essential components of biological pathways. Phosphorylaton by protein kinases and dephosphorylation by protein phosphatases exert major regulatory roles. In addition, they can also initiate intracellular signaling cascades. Kinases represent a significant fraction of eukaryotic genes and prominent amongst them are the serine/threonine kinases.


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altered Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
altered extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425 PMID:21277552 PMID:20951313 PMID:18098337 RGD:2293882, RGD:5133243, RGD:5133242, RGD:2298531 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Kras KRAS proto-oncogene, GTPase TAS
ISO 		RGD PMID:16112461 PMID:18772397 PMID:19506583 PMID:20951313 PMID:19078924 RGD:2306732, RGD:5490966, RGD:5490965, RGD:5133242, RGD:4143515 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO RGD PMID:20951313 PMID:21277552 RGD:5133242, RGD:5133243 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425 RGD:2293882 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
altered Jak-Stat signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 ISS RGD PMID:12032773 RGD:1357939 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jak3 Janus kinase 3 ISS RGD PMID:12032773 RGD:1357939 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
altered phosphatidylinositol 3-kinase-Akt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18955974 PMID:21277552 RGD:2313763, RGD:5133243 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:18955974 PMID:19506583 PMID:15166380 RGD:2313763, RGD:5490965, RGD:2313408 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO RGD PMID:18955974 RGD:2313763 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO RGD PMID:18955974 PMID:21277552 PMID:20951313 PMID:19078924 RGD:2313763, RGD:5133243, RGD:5133242, RGD:4143515 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pten phosphatase and tensin homolog ISO RGD PMID:18955974 PMID:19506583 PMID:20951313 PMID:19078924 PMID:18008377 RGD:2313763, RGD:5490965, RGD:5133242, RGD:4143515, RGD:2326139 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
ataxia telangiectasia-mutated (ATM) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO RGD PMID:23532176 PMID:21533982 RGD:8661225, RGD:8661232 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B ISO RGD PMID:24002223 RGD:8661242 NCBI chr12:27,068,541...27,126,511
Ensembl chr12:27,068,541...27,126,511 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO RGD PMID:24326623 RGD:8661237 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:2,073,184...2,084,185 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852 		JBrowse link
G H2ax H2A.X variant histone ISO RGD PMID:21533982 PMID:24002223 RGD:8661232, RGD:8661242 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Kat5 lysine acetyltransferase 5 ISO RGD PMID:23532176 PMID:21533982 RGD:8661225, RGD:8661232 NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587 		JBrowse link
G Kdm4a lysine demethylase 4A ISO RGD PMID:24326623 PMID:24002223 RGD:8661237, RGD:8661242 NCBI chr 5:136,958,178...137,004,942
Ensembl chr 5:136,958,178...137,004,951 		JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 ISO RGD PMID:24326623 PMID:24002223 RGD:8661237, RGD:8661242 NCBI chr 3:172,014,774...172,053,181
Ensembl chr 3:172,021,416...172,053,181 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 ISO RGD PMID:21533982 PMID:24002223 RGD:8661232, RGD:8661242 NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO RGD PMID:21533982 RGD:8661232 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Nbn nibrin ISO RGD PMID:21533982 RGD:8661232 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 7:9,197,032...9,210,557
Ensembl chr 7:9,196,896...9,210,527 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO RGD PMID:21533982 PMID:24002223 RGD:8661232, RGD:8661242 NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21533982 PMID:24002223 RGD:8661232, RGD:8661242 NCBI chr10:36,856,534...36,878,789 JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit ISO RGD PMID:24002223 RGD:8661242 NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit ISO RGD PMID:21533982 RGD:8661232 NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950 		JBrowse link
G Ppp6c protein phosphatase 6, catalytic subunit ISO RGD PMID:24002223 RGD:8661242 NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:43,341,108...43,371,807 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:66,662,900...66,755,665 		JBrowse link
G Pwwp3a PWWP domain containing 3A, DNA repair factor ISO RGD PMID:24326623 RGD:8661237 NCBI chr 7:10,115,865...10,132,696
Ensembl chr 7:10,115,866...10,130,925 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO RGD PMID:21533982 RGD:8661232 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease ISO RGD PMID:24326623 RGD:8661237 NCBI chr18:3,198,188...3,263,643
Ensembl chr18:3,197,310...3,263,985 		JBrowse link
G Rif1 replication timing regulatory factor 1 ISO RGD PMID:24326623 RGD:8661237 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Rnf168 ring finger protein 168 ISO RGD PMID:21533982 PMID:24326623 RGD:8661232, RGD:8661237 NCBI chr11:81,991,352...82,013,306
Ensembl chr11:81,991,360...82,013,306 		JBrowse link
G Rnf20 ring finger protein 20 ISO RGD PMID:23532176 RGD:8661225 NCBI chr 5:68,771,507...68,797,240
Ensembl chr 5:68,771,535...68,797,240 		JBrowse link
G Rnf4 ring finger protein 4 ISO RGD PMID:24002223 RGD:8661242 NCBI chr14:80,625,864...80,647,138
Ensembl chr14:80,625,866...80,647,148 		JBrowse link
G Rnf40 ring finger protein 40 ISO RGD PMID:23532176 RGD:8661225 NCBI chr 1:191,632,988...191,649,231
Ensembl chr 1:191,633,034...191,648,421 		JBrowse link
G Rnf8 ring finger protein 8 ISO RGD PMID:21533982 PMID:24326623 RGD:8661232, RGD:8661237 NCBI chr20:7,683,890...7,708,437 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO RGD PMID:24326623 RGD:8661237 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747 		JBrowse link
G Trip12 thyroid hormone receptor interactor 12 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 9:93,364,791...93,491,015
Ensembl chr 9:93,364,791...93,490,159 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N ISO RGD PMID:21533982 PMID:24326623 RGD:8661232, RGD:8661237 NCBI chr 7:32,041,190...32,071,252 JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:71,000,197...71,109,813 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 ISO RGD PMID:24002223 RGD:8661242 NCBI chr11:40,166,651...40,196,792
Ensembl chr11:40,167,692...40,196,823 		JBrowse link
G Usp3 ubiquitin specific peptidase 3 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 8:75,973,278...76,049,151
Ensembl chr 8:75,974,615...76,049,153 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 ISO RGD PMID:24002223 RGD:8661242 NCBI chr 7:30,251,142...30,301,185
Ensembl chr 7:30,251,205...30,297,906 		JBrowse link
G Vcp valosin-containing protein ISO RGD PMID:24326623 PMID:24002223 RGD:8661237, RGD:8661242 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387 		JBrowse link
c-Jun N-terminal kinases MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:17208316 RGD:2293881 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:17208316 RGD:2293881 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508 		JBrowse link
G Dusp19 dual specificity phosphatase 19 ISO RGD PMID:11959862 RGD:2314491 NCBI chr 3:85,945,289...86,081,289 JBrowse link
G Dusp8 dual specificity phosphatase 8 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO
IDA 		RGD PMID:17306896 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO
IDA 		RGD PMID:17306896 PMID:17064355 PMID:15680699 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298567, RGD:2298561 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:7,389,155...7,398,377 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 1:92,083,376...92,101,676
Ensembl chr 1:92,083,376...92,101,676 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO
IDA 		RGD PMID:8910292 PMID:17064355 PMID:15680699 PMID:17306896 RGD:2293876, RGD:2298577, RGD:2298567, RGD:2293875 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 ISO RGD PMID:17306896 RGD:2293875 NCBI chr11:92,596,436...92,741,717
Ensembl chr11:92,601,738...92,739,663 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538 		JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 ISO RGD PMID:17306896 RGD:2293875 NCBI chr19:70,776,233...70,810,889
Ensembl chr19:70,777,472...70,810,882 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:12215209 PMID:17306896 RGD:2293875 RGD:2296020 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 6:107,155,008...107,220,304
Ensembl chr 6:107,161,534...107,220,061 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 ISO
IDA 		RGD PMID:17306896 PMID:15680699 PMID:10051439 RGD:2293875, RGD:2298567, RGD:2298561 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO
IDA 		RGD PMID:17306896 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 ISO
IDA 		RGD PMID:17726577 PMID:15816852 RGD:2293880, RGD:1579811 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:17726577 RGD:2293880 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 ISO RGD PMID:17726577 RGD:2293880 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:14,422,936...14,462,812 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO
IDA 		RGD PMID:17306896 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:33,296,230...33,414,119 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO RGD PMID:12215209 RGD:2296020 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:23091085 RGD:7240708 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr17:82,473,097...82,818,564
Ensembl chr17:82,473,129...82,818,564 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:22334212 RGD:7240704 NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757 		JBrowse link
G Calm1 calmodulin 1 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calm2 calmodulin 2 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Calm3 calmodulin 3 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISO RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma ISO RGD PMID:22717267 RGD:7240705 NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706, RGD:7240707 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058 		JBrowse link
G Camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706, RGD:7240707 NCBI chr11:93,792,112...93,796,153
Ensembl chr11:93,794,095...93,795,222 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:22334212 RGD:7240704 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:22717267 RGD:7240705 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570 		JBrowse link
G Hdac4 histone deacetylase 4 ISO RGD PMID:21255680 RGD:7241019 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:99,955,116...100,197,637 		JBrowse link
G Hdac5 histone deacetylase 5 ISO RGD PMID:21255680 RGD:7241019 NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:249,805,448...250,293,718 		JBrowse link
G Pln phospholamban ISO RGD PMID:23091085 RGD:7240708 NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241 		JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent, 1E ISO RGD PMID:18454172 RGD:7241020 NCBI chr10:72,548,906...72,684,702
Ensembl chr10:72,552,469...72,684,546 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F TAS RGD PMID:18454172 RGD:7241020 NCBI chr11:97,568,627...97,598,613
Ensembl chr11:97,568,625...97,598,545 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:18454172 RGD:7241020 NCBI chr12:40,043,822...40,061,301
Ensembl chr12:40,043,822...40,061,341 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha TAS RGD PMID:18454172 RGD:7241020 NCBI chr10:36,856,534...36,878,789 JBrowse link
G Ryr2 ryanodine receptor 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr20:5,028,226...5,058,519
Ensembl chr20:5,026,707...5,057,751 		JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednrb endothelin receptor type B IMP RGD PMID:15245872 RGD:1581866 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO
IMP 		RGD PMID:16376520 PMID:15631999 RGD:2298532, RGD:1582263 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:16376520 RGD:2298532 NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO
IMP 		RGD PMID:16376520 PMID:11782488 RGD:2298532, RGD:2298794 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Sh2d2a SH2 domain containing 2A ISO RGD PMID:16376520 RGD:2298532 NCBI chr 2:175,610,127...175,616,685
Ensembl chr 2:175,609,874...175,616,685 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:154,800,590...154,926,147 		JBrowse link
Jak-Stat signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IEA KEGG rno:04630 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04630 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04630 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Bcl2l1 Bcl2-like 1 IEA KEGG rno:04630 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Cbl Cbl proto-oncogene IEA KEGG rno:04630 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067 		JBrowse link
G Cblb Cbl proto-oncogene B IEA KEGG rno:04630 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778 		JBrowse link
G Cblc Cbl proto-oncogene C IEA KEGG rno:04630 NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709 		JBrowse link
G Ccnd1 cyclin D1 IEA KEGG rno:04630 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd2 cyclin D2 IEA KEGG rno:04630 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Ccnd3 cyclin D3 IEA KEGG rno:04630 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Cish cytokine inducible SH2-containing protein IEA KEGG rno:04630 NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 IEA KEGG rno:04630 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Cntf ciliary neurotrophic factor IEA KEGG rno:04630 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Cntfr ciliary neurotrophic factor receptor IEA KEGG rno:04630 NCBI chr 5:61,619,326...61,657,359
Ensembl chr 5:61,619,326...61,645,795 		JBrowse link
G Crebbp CREB binding protein IEA KEGG rno:04630 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 IEA KEGG rno:04630 NCBI chr14:118,932...123,632
Ensembl chr14:115,497...123,631 		JBrowse link
G Csf2 colony stimulating factor 2 IEA KEGG rno:04630 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha IEA KEGG rno:04630 NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta IEA KEGG rno:04630 NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654 		JBrowse link
G Csf3 colony stimulating factor 3 IEA KEGG rno:04630 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Csf3r colony stimulating factor 3 receptor IEA KEGG rno:04630 NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411 		JBrowse link
G Ctf1 cardiotrophin 1 IEA KEGG rno:04630 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Ep300 E1A binding protein p300 IEA KEGG rno:04630 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Epo erythropoietin IEA KEGG rno:04630 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Epor erythropoietin receptor IEA KEGG rno:04630 NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322 		JBrowse link
G Gh1 growth hormone 1 IEA KEGG rno:04630 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Ghr growth hormone receptor IEA KEGG rno:04630 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Grb2 growth factor receptor bound protein 2 IEA KEGG rno:04630 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Ifna1 interferon, alpha 1 IEA KEGG rno:04630 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Ifna2 interferon alpha 2 IEA KEGG rno:04630 NCBI chr 5:108,374,363...108,374,941
Ensembl chr 5:108,374,363...108,374,941 		JBrowse link
G Ifna4 interferon, alpha 4 IEA KEGG rno:04630 NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:108,115,064...108,116,010 		JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 IEA KEGG rno:04630 NCBI chr 5:108,640,546...108,641,115 JBrowse link
G Ifna5 interferon, alpha 5 IEA KEGG rno:04630 NCBI chr 5:108,233,736...108,234,314
Ensembl chr 5:108,233,736...108,234,314 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 IEA KEGG rno:04630 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205 		JBrowse link
G Ifnb1 interferon beta 1 IEA KEGG rno:04630 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma IEA KEGG rno:04630 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IEA KEGG rno:04630 NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437 		JBrowse link
G Ifngr2 interferon gamma receptor 2 IEA KEGG rno:04630 NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975 		JBrowse link
G Ifnk interferon kappa IEA KEGG rno:04630 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511 		JBrowse link
G Ifnl3 interferon, lambda 3 IEA KEGG rno:04630 NCBI chr 1:92,941,988...92,943,628 JBrowse link
G Ifnlr1 interferon, lambda receptor 1 IEA KEGG rno:04630 NCBI chr 5:153,203,597...153,225,911
Ensembl chr 5:153,203,597...153,225,911 		JBrowse link
G Il10 interleukin 10 IEA KEGG rno:04630 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha IEA KEGG rno:04630 NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta IEA KEGG rno:04630 NCBI chr11:44,132,471...44,154,062
Ensembl chr11:44,132,189...44,154,053 		JBrowse link
G Il11 interleukin 11 IEA KEGG rno:04630 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 IEA KEGG rno:04630 NCBI chr 5:61,727,650...61,737,265
Ensembl chr 5:61,727,931...61,737,264 		JBrowse link
G Il12a interleukin 12A IEA KEGG rno:04630 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B IEA KEGG rno:04630 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 IEA KEGG rno:04630 NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,654,207...18,666,824 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 IEA KEGG rno:04630 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G Il13 interleukin 13 IEA KEGG rno:04630 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IEA KEGG rno:04630 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 IEA KEGG rno:04630 NCBI chr  X:115,814,620...115,886,080
Ensembl chr  X:115,814,622...115,841,455 		JBrowse link
G Il15 interleukin 15 IDA
IEA 		KEGG
RGD		 PMID:8942753 rno:04630, RGD:5024920 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha IMP RGD PMID:19747902 RGD:5001122 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149 		JBrowse link
G Il19 interleukin 19 IEA KEGG rno:04630 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714 		JBrowse link
G Il2 interleukin 2 IEA KEGG rno:04630 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il20 interleukin 20 IEA KEGG rno:04630 NCBI chr13:44,933,249...44,936,893
Ensembl chr13:44,933,249...44,936,893 		JBrowse link
G Il20ra interleukin 20 receptor subunit alpha IEA KEGG rno:04630 NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:16,243,801...16,313,221 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta IEA KEGG rno:04630 NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363 		JBrowse link
G Il21 interleukin 21 IEA KEGG rno:04630 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il21r interleukin 21 receptor IEA KEGG rno:04630 NCBI chr 1:189,598,682...189,626,340
Ensembl chr 1:189,598,558...189,626,342 		JBrowse link
G Il22 interleukin 22 IEA KEGG rno:04630 NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201 		JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 IEA KEGG rno:04630 NCBI chr 5:153,245,067...153,269,865
Ensembl chr 5:153,245,002...153,271,683 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 IEA KEGG rno:04630 NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950 		JBrowse link
G Il23a interleukin 23 subunit alpha IEA KEGG rno:04630 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il23r interleukin 23 receptor IEA KEGG rno:04630 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:97,909,972...98,004,110 		JBrowse link
G Il24 interleukin 24 IEA KEGG rno:04630 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IEA KEGG rno:04630 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta IEA KEGG rno:04630 NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma IEA KEGG rno:04630 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Il3 interleukin 3 IEA KEGG rno:04630 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il3ra interleukin 3 receptor subunit alpha IEA KEGG rno:04630 NCBI chr12:21,431,848...21,437,336
Ensembl chr12:21,431,848...21,437,250 		JBrowse link
G Il4 interleukin 4 IEA KEGG rno:04630 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il4r interleukin 4 receptor IEA KEGG rno:04630 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il5 interleukin 5 IEA KEGG rno:04630 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha IEA KEGG rno:04630 NCBI chr 4:141,186,749...141,221,348
Ensembl chr 4:141,171,158...141,220,943 		JBrowse link
G Il6 interleukin 6 IEA KEGG rno:04630 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor IEA KEGG rno:04630 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer IEA KEGG rno:04630 NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182 		JBrowse link
G Il7 interleukin 7 IEA KEGG rno:04630 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Il7r interleukin 7 receptor IEA KEGG rno:04630 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027 		JBrowse link
G Il9 interleukin 9 IEA KEGG rno:04630 NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,117,028...8,120,151 		JBrowse link
G Il9r interleukin 9 receptor IEA KEGG rno:04630 NCBI chr10:15,936,156...15,947,613
Ensembl chr10:15,936,156...15,947,613 		JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:20980260 RGD:5128774 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Irf9 interferon regulatory factor 9 IEA KEGG rno:04630 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Jak1 Janus kinase 1 TAS
IEA
ISO 		KEGG
RGD		 PMID:12087100 PMID:17312100 rno:04630, RGD:1299183, RGD:1625126 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 IEA
ISO
IDA 		KEGG
RGD		 PMID:17312100 PMID:11064147 PMID:12107179 rno:04630, RGD:1625126, RGD:1624963, RGD:632386 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jak3 Janus kinase 3 ISS
IEA
ISO 		KEGG
RGD		 PMID:8143863 PMID:17312100 rno:04630, RGD:729028, RGD:1625126 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Lep leptin IEA KEGG rno:04630 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lepr leptin receptor IEA KEGG rno:04630 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lif LIF, interleukin 6 family cytokine IEA KEGG rno:04630 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Lifr LIF receptor subunit alpha IEA KEGG rno:04630 NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor IEA KEGG rno:04630 NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:137,259,288...137,272,177 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEA KEGG rno:04630 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Osm oncostatin M IEA KEGG rno:04630 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G Osmr oncostatin M receptor IEA KEGG rno:04630 NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 ISO
IEA 		KEGG
RGD		 PMID:14607831 PMID:16426581 rno:04630, RGD:1357941, RGD:2290530 NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 ISO
IEA 		KEGG
RGD		 PMID:16426581 rno:04630, RGD:2290530 NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662 		JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 ISS
IEA
ISO 		KEGG
RGD		 PMID:14607831 PMID:16426581 rno:04630, RGD:1357941, RGD:2290530 NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:186,921,428...186,936,714 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 ISO
IEA 		KEGG
RGD		 PMID:14607831 PMID:16426581 rno:04630, RGD:1357941, RGD:2290530 NCBI chr 7:9,197,032...9,210,557
Ensembl chr 7:9,196,896...9,210,527 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IEA KEGG rno:04630 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:04630 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:04630 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG rno:04630 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:04630 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:04630 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:04630 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase IEA KEGG rno:04630 NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764 		JBrowse link
G Prl prolactin IEA KEGG rno:04630 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Prlr prolactin receptor IEA KEGG rno:04630 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:11818507 RGD:633057 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO RGD PMID:16426581 RGD:2290530 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO
IEA 		KEGG
RGD		 PMID:16426581 rno:04630, RGD:2290530 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO RGD PMID:16426581 RGD:2290530 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 ISO
IEA 		KEGG
RGD		 PMID:16426581 rno:04630, RGD:2290530 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISS
IEA 		KEGG
RGD		 PMID:12039028 rno:04630, RGD:1357935 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISS
IEA 		KEGG
RGD		 PMID:12039028 rno:04630, RGD:1357935 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISS
IEA 		KEGG
RGD		 PMID:12039028 rno:04630, RGD:1357935 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 ISO
IEA 		KEGG
RGD		 PMID:14607831 rno:04630, RGD:1357941 NCBI chr15:23,003,130...23,017,615
Ensembl chr15:23,002,883...23,022,499 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 ISO
IEA 		KEGG
RGD		 PMID:14607831 rno:04630, RGD:1357941 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Socs6 suppressor of cytokine signaling 6 ISO RGD PMID:14607831 RGD:1357941 NCBI chr18:84,386,587...84,413,927
Ensembl chr18:84,384,573...84,414,053 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 ISO
IEA 		KEGG
RGD		 PMID:14607831 rno:04630, RGD:1357941 NCBI chr10:82,848,525...82,885,201
Ensembl chr10:82,848,612...82,885,201 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA KEGG rno:04630 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG rno:04630 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:93,778,971...93,892,811 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 IEA KEGG rno:04630 NCBI chr 3:124,437,230...124,504,358
Ensembl chr 3:124,437,230...124,504,358 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 IEA KEGG rno:04630 NCBI chr14:98,350,577...98,452,143
Ensembl chr14:98,350,290...98,452,143 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 IEA KEGG rno:04630 NCBI chr 1:93,586,259...93,597,692
Ensembl chr 1:93,586,259...93,598,254 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 IEA KEGG rno:04630 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074 		JBrowse link
G Spry3 sprouty RTK signaling antagonist 3 IEA KEGG rno:04630 NCBI chr12:21,777,090...21,786,280
Ensembl chr12:21,776,005...21,786,804 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 IEA KEGG rno:04630 NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,687,039...30,704,173 		JBrowse link
G Stam signal transducing adaptor molecule IEA KEGG rno:04630 NCBI chr17:82,028,779...82,074,717
Ensembl chr17:82,028,703...82,075,013 		JBrowse link
G Stam2 signal transducing adaptor molecule 2 IEA KEGG rno:04630 NCBI chr 3:57,597,557...57,643,915
Ensembl chr 3:57,597,559...57,643,915 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA
IEA
ISO 		KEGG
RGD		 PMID:12191995 PMID:17312100 rno:04630, RGD:1299060, RGD:1625126 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 ISO
IEA 		KEGG
RGD		 PMID:12039028 PMID:17312100 rno:04630, RGD:1357935, RGD:1625126 NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 TAS
IEA
ISO 		KEGG
RGD		 PMID:12087100 PMID:17312100 rno:04630, RGD:1299183, RGD:1625126 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO
IEA 		KEGG
RGD		 PMID:12039028 PMID:17312100 rno:04630, RGD:1357935, RGD:1625126 NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISS
IEA
ISO
IDA 		KEGG
RGD		 PMID:12039028 PMID:17312100 PMID:11064147 rno:04630, RGD:1357935, RGD:1625126, RGD:1624963 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IDA
IEA
ISO 		KEGG
RGD		 PMID:12193540 PMID:17312100 PMID:11064147 rno:04630, RGD:628356, RGD:1625126, RGD:1624963 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO
IEA 		KEGG
RGD		 PMID:12039028 PMID:17312100 rno:04630, RGD:1357935, RGD:1625126 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Tpo thyroid peroxidase IEA KEGG rno:04630 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793 		JBrowse link
G Tslp thymic stromal lymphopoietin IEA KEGG rno:04630 NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420 		JBrowse link
G Tyk2 tyrosine kinase 2 ISO RGD PMID:12039028 PMID:17312100 RGD:1357935, RGD:1625126 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278 		JBrowse link
mitogen activated protein kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Arrb1 arrestin, beta 1 IEA KEGG rno:04010 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Arrb2 arrestin, beta 2 IEA KEGG rno:04010 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Atf2 activating transcription factor 2 IEA KEGG rno:04010 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Atf4 activating transcription factor 4 IEA KEGG rno:04010 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEA KEGG rno:04010 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA KEGG rno:04010 NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IEA KEGG rno:04010 NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:27,779,166...27,944,285 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEA KEGG rno:04010 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEA KEGG rno:04010 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E IEA KEGG rno:04010 NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983 		JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F IEA KEGG rno:04010 NCBI chr  X:17,539,992...17,568,308
Ensembl chr  X:17,539,920...17,568,308 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IEA KEGG rno:04010 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IEA KEGG rno:04010 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IEA KEGG rno:04010 NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:113,716,266...113,827,670 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S IEA KEGG rno:04010 NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IEA KEGG rno:04010 NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 IEA KEGG rno:04010 NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 IEA KEGG rno:04010 NCBI chr16:4,105,048...4,919,037
Ensembl chr16:4,105,048...4,919,098 		JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 IEA KEGG rno:04010 NCBI chr 4:154,080,877...154,197,369
Ensembl chr 4:154,080,877...154,193,778 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 IEA KEGG rno:04010 NCBI chr10:83,494,509...83,515,164
Ensembl chr10:83,494,509...83,515,146 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 IEA KEGG rno:04010 NCBI chr17:82,473,097...82,818,564
Ensembl chr17:82,473,129...82,818,564 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IEA KEGG rno:04010 NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:131,662,545...131,676,085 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IEA KEGG rno:04010 NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:57,315,900...57,578,220 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 IEA KEGG rno:04010 NCBI chr10:93,152,558...93,165,246
Ensembl chr10:93,152,248...93,165,417 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 IEA KEGG rno:04010 NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757 		JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 IEA KEGG rno:04010 NCBI chr 1:186,632,334...186,728,220
Ensembl chr 1:186,632,323...186,728,214 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IEA KEGG rno:04010 NCBI chr10:93,183,410...93,245,470
Ensembl chr10:93,183,410...93,245,470 		JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 IEA KEGG rno:04010 NCBI chr10:93,327,142...93,369,244
Ensembl chr10:93,327,150...93,336,667 		JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 IEA KEGG rno:04010 NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:74,648,063...74,662,753 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 IEA KEGG rno:04010 NCBI chr 1:74,715,483...74,746,669
Ensembl chr 1:74,715,483...74,746,669 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 IEA KEGG rno:04010 NCBI chr 1:74,670,767...74,691,003
Ensembl chr 1:74,669,766...74,694,015 		JBrowse link
G Casp3 caspase 3 IEA KEGG rno:04010 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccdc88b coiled-coil domain containing 88B IEA KEGG rno:04010 NCBI chr 1:213,466,139...213,482,099
Ensembl chr 1:213,461,963...213,522,302 		JBrowse link
G Cd14 CD14 molecule IEA KEGG rno:04010 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cdc25b cell division cycle 25B IEA KEGG rno:04010 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492 		JBrowse link
G Cdc42 cell division cycle 42 IEA KEGG rno:04010 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 IEA KEGG rno:04010 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443 		JBrowse link
G Chp1l1 calcineurin-like EF-hand protein 1 like 1 IEA KEGG rno:04010 NCBI chr 5:73,364,780...73,367,229
Ensembl chr 5:73,363,560...73,367,249 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 IEA KEGG rno:04010 NCBI chr 1:186,189,090...186,203,663
Ensembl chr 1:186,185,151...186,203,667 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG rno:04010 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457 		JBrowse link
G Daxx death-domain associated protein IEA KEGG rno:04010 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEA KEGG rno:04010 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEA KEGG rno:04010 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 IEA KEGG rno:04010 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp14 dual specificity phosphatase 14 IEA KEGG rno:04010 NCBI chr10:69,433,949...69,463,863
Ensembl chr10:69,426,730...69,462,837 		JBrowse link
G Dusp16 dual specificity phosphatase 16 IEA KEGG rno:04010 NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508 		JBrowse link
G Dusp2 dual specificity phosphatase 2 IEA KEGG rno:04010 NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809 		JBrowse link
G Dusp22 dual specificity phosphatase 22 IEA KEGG rno:04010 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895 		JBrowse link
G Dusp3 dual specificity phosphatase 3 IEA KEGG rno:04010 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063 		JBrowse link
G Dusp4 dual specificity phosphatase 4 IEA KEGG rno:04010 NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700 		JBrowse link
G Dusp5 dual specificity phosphatase 5 IEA KEGG rno:04010 NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417 		JBrowse link
G Dusp6 dual specificity phosphatase 6 IEA KEGG rno:04010 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833 		JBrowse link
G Dusp7 dual specificity phosphatase 7 IEA KEGG rno:04010 NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:115,887,892...115,895,126 		JBrowse link
G Dusp8 dual specificity phosphatase 8 IEA KEGG rno:04010 NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441 		JBrowse link
G Dusp9 dual specificity phosphatase 9 IEA KEGG rno:04010 NCBI chr  X:156,503,237...156,507,162
Ensembl chr  X:156,503,190...156,507,161 		JBrowse link
G Ecsit ECSIT signaling integrator IEA KEGG rno:04010 NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:28,881,594...28,894,397 		JBrowse link
G Egf epidermal growth factor IEA KEGG rno:04010 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor IEA KEGG rno:04010 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Elk1 ETS transcription factor ELK1 IEA KEGG rno:04010 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Elk4 ETS transcription factor ELK4 IEA KEGG rno:04010 NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:16168116 RGD:1582137 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Fas Fas cell surface death receptor IEA KEGG rno:04010 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand IEA KEGG rno:04010 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fgf1 fibroblast growth factor 1 IEA KEGG rno:04010 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgf10 fibroblast growth factor 10 IEA KEGG rno:04010 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980 		JBrowse link
G Fgf11 fibroblast growth factor 11 IEA KEGG rno:04010 NCBI chr10:55,015,232...55,020,773
Ensembl chr10:55,016,411...55,020,454 		JBrowse link
G Fgf12 fibroblast growth factor 12 IEA KEGG rno:04010 NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543 		JBrowse link
G Fgf13 fibroblast growth factor 13 IEA KEGG rno:04010 NCBI chr  X:142,312,381...142,838,581
Ensembl chr  X:142,312,391...142,423,536 		JBrowse link
G Fgf14 fibroblast growth factor 14 IEA KEGG rno:04010 NCBI chr15:107,442,800...108,086,486
Ensembl chr15:107,451,634...108,085,808 		JBrowse link
G Fgf16 fibroblast growth factor 16 IEA KEGG rno:04010 NCBI chr  X:74,882,863...74,893,598
Ensembl chr  X:74,882,995...74,944,246 		JBrowse link
G Fgf17 fibroblast growth factor 17 IEA KEGG rno:04010 NCBI chr15:52,118,141...52,132,083
Ensembl chr15:52,121,191...52,132,016 		JBrowse link
G Fgf18 fibroblast growth factor 18 IEA KEGG rno:04010 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933 		JBrowse link
G Fgf19 fibroblast growth factor 19 IEA KEGG rno:04010 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267 		JBrowse link
G Fgf2 fibroblast growth factor 2 IEA KEGG rno:04010 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf20 fibroblast growth factor 20 IEA KEGG rno:04010 NCBI chr16:58,734,003...58,741,650
Ensembl chr16:58,734,003...58,741,627 		JBrowse link
G Fgf21 fibroblast growth factor 21 IEA KEGG rno:04010 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056 		JBrowse link
G Fgf22 fibroblast growth factor 22 IEA KEGG rno:04010 NCBI chr 7:10,598,254...10,600,945
Ensembl chr 7:10,597,538...10,600,945 		JBrowse link
G Fgf23 fibroblast growth factor 23 IEA KEGG rno:04010 NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991 		JBrowse link
G Fgf3 fibroblast growth factor 3 IEA KEGG rno:04010 NCBI chr 1:209,430,457...209,434,832
Ensembl chr 1:209,430,457...209,434,832 		JBrowse link
G Fgf4 fibroblast growth factor 4 IEA KEGG rno:04010 NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085 		JBrowse link
G Fgf5 fibroblast growth factor 5 IEA KEGG rno:04010 NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,627,906...11,650,243 		JBrowse link
G Fgf6 fibroblast growth factor 6 IEA KEGG rno:04010 NCBI chr 4:161,541,089...161,549,624
Ensembl chr 4:161,541,089...161,553,521 		JBrowse link
G Fgf7 fibroblast growth factor 7 IEA KEGG rno:04010 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328 		JBrowse link
G Fgf8 fibroblast growth factor 8 IEA KEGG rno:04010 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605 		JBrowse link
G Fgf9 fibroblast growth factor 9 IEA KEGG rno:04010 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEA KEGG rno:04010 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IEA KEGG rno:04010 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 IEA KEGG rno:04010 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 IEA KEGG rno:04010 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389 		JBrowse link
G Flna filamin A IEA KEGG rno:04010 NCBI chr  X:157,159,051...157,185,559
Ensembl chr  X:157,159,051...157,182,343 		JBrowse link
G Flnb filamin B IEA KEGG rno:04010 NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209 		JBrowse link
G Flnc filamin C IEA KEGG rno:04010 NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha IEA KEGG rno:04010 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta IEA KEGG rno:04010 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma IEA KEGG rno:04010 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Gna12 G protein subunit alpha 12 IEA KEGG rno:04010 NCBI chr12:18,919,629...19,000,185
Ensembl chr12:18,919,629...19,000,185 		JBrowse link
G Gng12 G protein subunit gamma 12 IEA KEGG rno:04010 NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476 		JBrowse link
G Grb2 growth factor receptor bound protein 2 IEA KEGG rno:04010 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Hras HRas proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IEA KEGG rno:04010 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IEA KEGG rno:04010 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like IEA KEGG rno:04010 NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 IEA KEGG rno:04010 NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEA KEGG rno:04010 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEA KEGG rno:04010 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG rno:04010 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG rno:04010 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:04010 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:04010 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 IEA KEGG rno:04010 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 IEA KEGG rno:04010 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA KEGG rno:04010 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 IEA KEGG rno:04010 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IEA KEGG rno:04010 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 IEA KEGG rno:04010 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEA KEGG rno:04010 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 IEA KEGG rno:04010 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:7,389,155...7,398,377 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 IEA KEGG rno:04010 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 IEA KEGG rno:04010 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 IEA KEGG rno:04010 NCBI chr11:92,596,436...92,741,717
Ensembl chr11:92,601,738...92,739,663 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IEA KEGG rno:04010 NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 IEA KEGG rno:04010 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 IEA KEGG rno:04010 NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IEA KEGG rno:04010 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 IEA KEGG rno:04010 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987 		JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr 6:20,029,246...20,198,583
Ensembl chr 6:20,029,397...20,198,583 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA KEGG rno:04010 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:04010 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA KEGG rno:04010 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG rno:04010 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA KEGG rno:04010 NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA KEGG rno:04010 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 IEA KEGG rno:04010 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA KEGG rno:04010 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IEA KEGG rno:04010 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IEA KEGG rno:04010 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 IEA KEGG rno:04010 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:14,422,936...14,462,812 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:04010 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 IEA KEGG rno:04010 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 IEA KEGG rno:04010 NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170 		JBrowse link
G Mapt microtubule-associated protein tau IEA KEGG rno:04010 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Max MYC associated factor X IEA KEGG rno:04010 NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:101,369,988...101,395,549 		JBrowse link
G Mecom MDS1 and EVI1 complex locus IEA KEGG rno:04010 NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038 		JBrowse link
G Mef2c myocyte enhancer factor 2C IEA KEGG rno:04010 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:134,554,943...134,594,393 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 5:21,657,549...21,658,856
Ensembl chr 5:21,657,431...21,658,987 		JBrowse link
G Mras muscle RAS oncogene homolog IEA KEGG rno:04010 NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEA KEGG rno:04010 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nf1 neurofibromin 1 IEA KEGG rno:04010 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 IEA KEGG rno:04010 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 IEA KEGG rno:04010 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEA KEGG rno:04010 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IEA KEGG rno:04010 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637 		JBrowse link
G Ngf nerve growth factor IEA KEGG rno:04010 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nlk nemo like kinase IEA KEGG rno:04010 NCBI chr10:63,965,432...64,089,006 JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IEA KEGG rno:04010 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543 		JBrowse link
G Ntf3 neurotrophin 3 IEA KEGG rno:04010 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Ntf4 neurotrophin 4 IEA KEGG rno:04010 NCBI chr 1:105,030,035...105,032,866
Ensembl chr 1:105,029,764...105,034,038 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEA KEGG rno:04010 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEA KEGG rno:04010 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 TAS
IEA 		KEGG
RGD		 PMID:9779826 rno:04010, RGD:70317 NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:161,491,847...161,637,612 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 IEA KEGG rno:04010 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803 		JBrowse link
G Pdgfa platelet derived growth factor subunit A IEA KEGG rno:04010 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA KEGG rno:04010 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEA KEGG rno:04010 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEA KEGG rno:04010 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233 		JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04010 NCBI chr10:2,104,927...2,117,998
Ensembl chr10:2,104,927...2,116,172 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04010 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04010 NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,913,259...27,932,148 		JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04010 NCBI chr12:46,802,932...46,814,511
Ensembl chr12:46,802,939...46,813,693 		JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04010 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04010 NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:156,242,451...156,264,676 		JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04010 NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:156,297,777...156,305,812 		JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04010 NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:156,270,077...156,295,516 		JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04010 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542 		JBrowse link
G Pla2g4a phospholipase A2 group 4A IEA KEGG rno:04010 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04010 NCBI chr 3:127,458,022...127,467,637
Ensembl chr 3:127,459,273...127,467,637 		JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04010 NCBI chr 3:127,586,318...127,652,369
Ensembl chr 3:127,587,027...127,651,868 		JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04010 NCBI chr 3:127,702,603...127,720,429
Ensembl chr 3:127,703,841...127,718,348 		JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04010 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926 		JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04010 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:112,731,803...112,771,609 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A IEA KEGG rno:04010 NCBI chr 6:97,174,955...97,216,585
Ensembl chr 6:97,174,916...97,216,574 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B IEA KEGG rno:04010 NCBI chr 6:15,399,559...15,460,301
Ensembl chr 6:15,399,562...15,460,756 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEA KEGG rno:04010 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA KEGG rno:04010 NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma IEA KEGG rno:04010 NCBI chr15:51,699,586...51,771,763
Ensembl chr15:51,700,255...51,771,538 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEA KEGG rno:04010 NCBI chr14:95,758,333...95,808,015 JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEA KEGG rno:04010 NCBI chr 5:68,822,387...68,823,382
Ensembl chr 5:68,822,387...68,823,818 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit IEA KEGG rno:04010 NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEA KEGG rno:04010 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA KEGG rno:04010 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315 		JBrowse link
G Prkca protein kinase C, alpha IEA KEGG rno:04010 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcb protein kinase C, beta IEA KEGG rno:04010 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04010 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit IEA KEGG rno:04010 NCBI chr  X:45,701,747...45,745,210
Ensembl chr  X:45,701,747...45,745,066 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEA KEGG rno:04010 NCBI chr 1:106,756,896...106,817,369
Ensembl chr 1:106,756,896...106,816,828 		JBrowse link
G Ptpn7 protein tyrosine phosphatase, non-receptor type 7 IEA KEGG rno:04010 NCBI chr13:49,122,679...49,136,096
Ensembl chr13:49,122,609...49,136,094 		JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R IEA KEGG rno:04010 NCBI chr 7:53,548,611...53,815,632
Ensembl chr 7:53,548,629...53,815,629 		JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG rno:04010 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:04010 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:55,308,922...55,342,217 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:166,505,868...166,726,698 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IEA KEGG rno:04010 NCBI chr 2:17,593,136...17,676,707
Ensembl chr 2:17,593,136...17,676,161 		JBrowse link
G Rasa2 RAS p21 protein activator 2 IEA KEGG rno:04010 NCBI chr 8:105,996,797...106,116,285
Ensembl chr 8:106,000,002...106,116,206 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEA KEGG rno:04010 NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:99,324,749...99,454,089 		JBrowse link
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 IEA KEGG rno:04010 NCBI chr 2:24,848,699...25,096,773
Ensembl chr 2:24,848,699...25,147,558 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA KEGG rno:04010 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434 		JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 IEA KEGG rno:04010 NCBI chr 1:213,135,034...213,152,246
Ensembl chr 1:213,136,015...213,151,884 		JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 IEA KEGG rno:04010 NCBI chr 6:25,647,386...25,745,952
Ensembl chr 6:25,647,386...25,710,591 		JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IEA KEGG rno:04010 NCBI chr 1:93,560,513...93,580,321
Ensembl chr 1:93,560,513...93,580,323 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEA KEGG rno:04010 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G RGD1565588 similar to calcium binding protein P22 IEA KEGG rno:04010
G Rps6ka1 ribosomal protein S6 kinase A1 IEA KEGG rno:04010 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 IEA KEGG rno:04010 NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 IEA KEGG rno:04010 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 IEA KEGG rno:04010 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 IEA KEGG rno:04010 NCBI chr  X:80,537,723...80,638,910
Ensembl chr  X:80,537,723...80,692,148 		JBrowse link
G Rras RAS related IEA KEGG rno:04010 NCBI chr 1:104,637,061...104,640,841
Ensembl chr 1:104,634,951...104,640,841 		JBrowse link
G Rras2 RAS related 2 IEA KEGG rno:04010 NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551 		JBrowse link
G Shc1 SHC adaptor protein 1 IDA RGD PMID:12837289 RGD:1304398 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA KEGG rno:04010 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:93,778,971...93,892,811 		JBrowse link
G Srf serum response factor IEA KEGG rno:04010 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:21,924,076...21,933,337 		JBrowse link
G Stk3 serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:67,938,378...68,208,508 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA KEGG rno:04010 NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:173,165,083...173,247,134 		JBrowse link
G Stmn1 stathmin 1 IEA KEGG rno:04010 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Taok1 TAO kinase 1 IEA KEGG rno:04010 NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595 		JBrowse link
G Taok2 TAO kinase 2 IEA KEGG rno:04010 NCBI chr 1:190,906,236...190,925,359
Ensembl chr 1:190,906,239...190,925,140 		JBrowse link
G Taok3 TAO kinase 3 IEA KEGG rno:04010 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:44,973,180...45,134,439 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:04010 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:04010 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:04010 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEA KEGG rno:04010 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEA KEGG rno:04010 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:04010 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEA KEGG rno:04010 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tp53 tumor protein p53 IEA KEGG rno:04010 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 IEA KEGG rno:04010 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
G Traf6 TNF receptor associated factor 6 IEA KEGG rno:04010 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600 		JBrowse link
Non-Stat, Jak dependent pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak1 Janus kinase 1 ISS RGD PMID:12884916 RGD:1357942 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Tyk2 tyrosine kinase 2 ISO RGD PMID:12884916 RGD:1357942 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278 		JBrowse link
p38 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IMP RGD PMID:16157033 RGD:1625329 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Atm ATM serine/threonine kinase ISO PID PID:200018 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Bnip2 BCL2 interacting protein 2 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:79,521,375...79,539,148
Ensembl chr 8:79,521,363...79,547,368 		JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200018 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200018 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200018 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO PID PID:200018 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Ccm2 CCM2 scaffold protein ISO PID
RGD		 PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr14:85,632,338...85,678,016
Ensembl chr14:85,632,001...85,678,028 		JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:42,032,921...42,119,451
Ensembl chr 8:42,033,042...42,119,345 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:20626350 RGD:7240533 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508 		JBrowse link
G Dusp9 dual specificity phosphatase 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr  X:156,503,237...156,507,162
Ensembl chr  X:156,503,190...156,507,161 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO PID PID:200018 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta ISO PID PID:200018 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma ISO PID PID:200018 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO
IDA 		PID
RGD		 PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO
IDA 		PID
RGD		 PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200018 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO PID PID:200018 NCBI chr 1:92,083,376...92,101,676
Ensembl chr 1:92,083,376...92,101,676 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO PID
RGD		 PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 ISO PID PID:200018 NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO
IDA 		PID
RGD		 PMID:17481747 PMID:20626350 PMID:16183734 PID:200018, RGD:2293891, RGD:7240533, RGD:2298758 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO RGD PMID:20626350 RGD:7240533 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO PID
RGD		 PMID:17481747 PID:200018, RGD:2293891 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 ISO RGD PMID:17481747 RGD:2293891 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 ISO RGD PMID:17481747 RGD:2293891 NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA
ISO 		PID
RGD		 PMID:16407200 PMID:17481747 PID:200018, RGD:1580544, RGD:2293891 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO
IMP 		RGD PMID:17481747 PMID:12024021 RGD:2293891, RGD:2302280 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:134,554,943...134,594,393 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID
RGD		 PMID:17481747 PID:200018, RGD:2293891 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:213,451,026...213,461,982
Ensembl chr 1:213,451,027...213,461,982 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Spag9 sperm associated antigen 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:79,440,311...79,574,709
Ensembl chr10:79,440,377...79,575,258 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO PID PID:200018 NCBI chr 7:113,556,157...113,587,351
Ensembl chr 7:113,555,819...113,587,351 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO PID PID:200018 NCBI chr 1:4,195,400...4,245,485
Ensembl chr 1:4,195,400...4,245,485 		JBrowse link
G Taok1 TAO kinase 1 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595 		JBrowse link
G Taok2 TAO kinase 2 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:190,906,236...190,925,359
Ensembl chr 1:190,906,239...190,925,140 		JBrowse link
G Taok3 TAO kinase 3 ISO PID PID:200018 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:44,973,180...45,134,439 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO PID
RGD		 PMID:12215209 PID:200018, RGD:2296020 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
G Traf6 TNF receptor associated factor 6 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Txn1 thioredoxin 1 ISO PID PID:200018 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
phosphatidylinositol 3-kinase-Akt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IDA
ISO
IMP 		PID
RGD		 PMID:12089343 PMID:37951850 PMID:27188433 PMID:17272396 PMID:12084817 More... PID:200197, RGD:632179, RGD:408345229, RGD:152995510, RGD:152177689, RGD:625444, RGD:2290458 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO PID
RGD		 PMID:17641274 PID:200197, RGD:2290458 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO PID
RGD		 PMID:17641274 PID:200197, RGD:2290458 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO PID PID:200197 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Casp9 caspase 9 ISO PID PID:200197 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO PID PID:200197 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO PID PID:200197 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO PID PID:200197 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Ckb creatine kinase B IMP RGD PMID:17272396 RGD:152177689 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478 		JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:17272396 RGD:152177689 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Foxo1 forkhead box O1 ISO PID PID:200197 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Foxo3 forkhead box O3 ISO PID PID:200197 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Foxo4 forkhead box O4 ISO PID PID:200197 NCBI chr  X:70,425,218...70,432,120
Ensembl chr  X:70,425,563...70,432,120 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO PID PID:200197 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:89,943,669...89,953,593 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200197 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:17272396 RGD:152177689 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200197 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO RGD PMID:17371235 RGD:2302068 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 ISO RGD PMID:17371235 RGD:2302068 NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:165,595,063...165,609,503 		JBrowse link
G Insr insulin receptor IEP RGD PMID:29896241 PMID:25352008 RGD:14700925, RGD:14700927 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Kpna1 karyopherin subunit alpha 1 ISO PID PID:200197 NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID PID:200197 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Mapkap1 MAPK associated protein 1 ISO PID PID:200197 NCBI chr 3:38,113,268...38,315,913
Ensembl chr 3:38,113,323...38,315,913 		JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog ISO PID PID:200197 NCBI chr10:14,002,927...14,008,678
Ensembl chr10:14,002,938...14,008,678 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO PID PID:200197 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO PID
RGD		 PMID:17641274 PID:200197, RGD:2290458 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Pgr progesterone receptor IMP RGD PMID:17272396 RGD:152177689 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 ISO RGD PMID:24794538 RGD:11535053 NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619 		JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 ISO RGD PMID:24794538 RGD:11535053 NCBI chr19:54,744,581...54,811,258
Ensembl chr19:54,744,581...54,812,259 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO RGD PMID:17641274 PMID:27188433 RGD:2290458, RGD:152995510 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta ISO RGD PMID:17641274 RGD:2290458 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta ISO RGD PMID:17641274 PMID:26311905 PMID:29893841 RGD:2290458, RGD:40890274, RGD:40890270 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO
IMP 		RGD PMID:29666415 PMID:29323718 PMID:21665152 RGD:38599151, RGD:38599216, RGD:38599159 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:17641274 RGD:2290458 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO RGD PMID:17641274 RGD:2290458 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 ISO RGD PMID:17641274 RGD:2290458 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr10:36,856,534...36,878,789 JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta ISO RGD PMID:23454242 RGD:11535052 NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta ISO RGD PMID:23454242 RGD:11535052 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:60,081,553...60,125,795 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha ISO RGD PMID:23454242 RGD:11535052 NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO PID PID:200197 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO PID PID:200197 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108 		JBrowse link
G Pten phosphatase and tensin homolog ISO RGD PMID:17641274 PMID:27188433 RGD:2290458, RGD:152995510 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200197 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO PID PID:200197 NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:57,539,311...57,631,288 		JBrowse link
G Sfn stratifin ISO PID PID:200197 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO PID PID:200197 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Sp1 Sp1 transcription factor IMP RGD PMID:17272396 RGD:152177689 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200197 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO PID PID:200197 NCBI chr15:84,670,756...84,848,876
Ensembl chr15:84,670,756...84,848,693 		JBrowse link
G Vegfa vascular endothelial growth factor A IMP RGD PMID:17272396 RGD:152177689 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta ISO PID PID:200197 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO PID PID:200197 NCBI chr10:61,082,934...61,120,618
Ensembl chr10:61,106,716...61,114,291 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma ISO PID PID:200197 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO PID PID:200197 NCBI chr14:81,920,819...81,930,202
Ensembl chr14:81,920,590...81,947,930 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta ISO PID PID:200197 NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta ISO PID PID:200197 NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:69,826,404...69,849,007 		JBrowse link
protein kinase A (PKA) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 ISO RGD PMID:18948702 RGD:2312469 NCBI chr14:86,125,119...86,234,459
Ensembl chr14:86,124,850...86,261,075 		JBrowse link
G Adcy10 adenylate cyclase 10 ISO RGD PMID:18948702 RGD:2312469 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926 		JBrowse link
G Adcy2 adenylate cyclase 2 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645 		JBrowse link
G Adcy3 adenylate cyclase 3 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173 		JBrowse link
G Adcy4 adenylate cyclase 4 ISO RGD PMID:18948702 RGD:2312469 NCBI chr15:33,236,201...33,252,070
Ensembl chr15:33,236,208...33,252,026 		JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:18948702 RGD:2312469 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343 		JBrowse link
G Adcy6 adenylate cyclase 6 ISO
IDA 		RGD PMID:18948702 PMID:15579502 RGD:2312469, RGD:2313211 NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770 		JBrowse link
G Adcy7 adenylate cyclase 7 ISO RGD PMID:18948702 RGD:2312469 NCBI chr19:34,913,154...34,972,366
Ensembl chr19:34,914,322...34,936,743 		JBrowse link
G Adcy8 adenylate cyclase 8 ISO RGD PMID:18948702 RGD:2312469 NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:98,306,464...98,555,038 		JBrowse link
G Adcy9 adenylate cyclase 9 ISO RGD PMID:18948702 RGD:2312469 NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792 		JBrowse link
G Akap1 A-kinase anchoring protein 1 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190 		JBrowse link
G Akap10 A-kinase anchoring protein 10 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr10:47,044,819...47,108,153
Ensembl chr10:47,044,819...47,108,203 		JBrowse link
G Akap11 A-kinase anchoring protein 11 ISO
IMP 		RGD PMID:14715913 PMID:19319965 PMID:18385542 RGD:2312475, RGD:2312477, RGD:2312637 NCBI chr15:60,320,839...60,365,480
Ensembl chr15:60,320,839...60,365,335 		JBrowse link
G Akap12 A-kinase anchoring protein 12 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557 		JBrowse link
G Akap13 A-kinase anchoring protein 13 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401 		JBrowse link
G Akap14 A-kinase anchoring protein 14 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr  X:121,261,195...121,276,376
Ensembl chr  X:121,259,899...121,276,376 		JBrowse link
G Akap3 A-kinase anchoring protein 3 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 4:161,374,198...161,400,062
Ensembl chr 4:161,374,407...161,400,230 		JBrowse link
G Akap4 A-kinase anchoring protein 4 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr  X:18,107,256...18,117,549
Ensembl chr  X:18,107,275...18,117,549 		JBrowse link
G Akap5 A-kinase anchoring protein 5 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620 		JBrowse link
G Akap6 A-kinase anchoring protein 6 ISO
IMP 		RGD PMID:14715913 PMID:11296225 PMID:19319965 RGD:2312475, RGD:68716, RGD:2312477 NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:75,919,513...76,355,036 		JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO
IMP 		RGD PMID:14715913 PMID:17901878 PMID:19319965 RGD:2312475, RGD:2312630, RGD:2312477 NCBI chr 1:21,906,503...22,168,663
Ensembl chr 1:21,906,676...22,037,090 		JBrowse link
G Akap8 A-kinase anchoring protein 8 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900 		JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:15911134 RGD:5131271 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:85,554,268...85,596,318 		JBrowse link
G Ezr ezrin ISO RGD PMID:14715913 RGD:2312475 NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor IMP RGD PMID:10446905 RGD:1598448 NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,973,352...9,011,654 		JBrowse link
G Pakap paralemmin A kinase anchor protein ISO RGD PMID:14715913 PMID:19319965 RGD:2312475, RGD:2312477 NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656 		JBrowse link
G Pde10a phosphodiesterase 10A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:54,313,343...54,765,668
Ensembl chr 1:54,317,732...54,764,051 		JBrowse link
G Pde11a phosphodiesterase 11A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 3:81,320,822...81,704,397
Ensembl chr 3:81,320,822...81,680,612 		JBrowse link
G Pde1a phosphodiesterase 1A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212 		JBrowse link
G Pde1b phosphodiesterase 1B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 7:136,505,834...136,533,034
Ensembl chr 7:136,505,689...136,533,033 		JBrowse link
G Pde1c phosphodiesterase 1C ISO RGD PMID:17376027 RGD:2312479 NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:86,626,282...87,193,259 		JBrowse link
G Pde2a phosphodiesterase 2A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466 		JBrowse link
G Pde3a phosphodiesterase 3A ISO RGD PMID:17376027 PMID:17376027 RGD:2312479, RGD:2312479 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270 		JBrowse link
G Pde3b phosphodiesterase 3B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:178,041,207...178,204,503 		JBrowse link
G Pde4a phosphodiesterase 4A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:27,966,996...28,046,924 		JBrowse link
G Pde4b phosphodiesterase 4B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pde4c phosphodiesterase 4C ISO RGD PMID:17376027 RGD:2312479 NCBI chr16:18,724,703...18,745,528
Ensembl chr16:18,725,674...18,744,037 		JBrowse link
G Pde4d phosphodiesterase 4D ISO
IMP 		RGD PMID:17376027 PMID:11296225 RGD:2312479, RGD:68716 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569 		JBrowse link
G Pde7a phosphodiesterase 7A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890 		JBrowse link
G Pde7b phosphodiesterase 7B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456 		JBrowse link
G Pde8a phosphodiesterase 8A ISO RGD PMID:17376027 RGD:2312479 NCBI chr 1:144,575,203...144,698,216
Ensembl chr 1:144,575,428...144,698,215 		JBrowse link
G Pde8b phosphodiesterase 8B ISO RGD PMID:17376027 RGD:2312479 NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:28,011,359...28,244,327 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha ISO RGD PMID:14715913 RGD:2312475 NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta ISO RGD PMID:14715913 RGD:2312475 NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411 		JBrowse link
protein kinase C (PKC) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone ISO RGD PMID:19934406 RGD:5131489 NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931 		JBrowse link
G Copb1 COPI coat complex subunit beta 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr 1:177,838,751...177,876,688
Ensembl chr 1:177,838,752...177,872,840 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO RGD PMID:15380937 RGD:5131492 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:19934406 RGD:5131489 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:15380937 RGD:5131492 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267 		JBrowse link
G Ldb3 LIM domain binding 3 ISO RGD PMID:18491053 PMID:15380937 RGD:5131491, RGD:5131492 NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,862,161...9,926,985 		JBrowse link
G Pard3 par-3 family cell polarity regulator ISO RGD PMID:16525119 RGD:5132275 NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941 		JBrowse link
G Pard6a par-6 family cell polarity regulator alpha ISO RGD PMID:16525119 RGD:5132275 NCBI chr19:50,499,420...50,502,301
Ensembl chr19:50,499,442...50,502,674 		JBrowse link
G Pard6b par-6 family cell polarity regulator beta ISO RGD PMID:16525119 RGD:5132275 NCBI chr 3:177,209,429...177,230,509
Ensembl chr 3:177,209,258...177,230,510 		JBrowse link
G Pard6g par-6 family cell polarity regulator gamma ISO RGD PMID:16525119 RGD:5132275 NCBI chr18:75,772,992...75,840,041
Ensembl chr18:75,772,955...75,840,041 		JBrowse link
G Pcnt pericentrin ISO RGD PMID:15380937 RGD:5131492 NCBI chr20:12,189,767...12,278,179
Ensembl chr20:12,192,353...12,278,178 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO RGD PMID:19934406 RGD:5131489 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 IMP
ISO 		RGD PMID:20819118 PMID:18511290 RGD:8693633, RGD:5131497 NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619 		JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 ISO RGD PMID:18511290 RGD:5131497 NCBI chr19:54,744,581...54,811,258
Ensembl chr19:54,744,581...54,812,259 		JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr 7:112,676,890...112,697,275
Ensembl chr 7:112,677,322...112,697,257 		JBrowse link
G Plcb1 phospholipase C beta 1 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646 		JBrowse link
G Plcb2 phospholipase C, beta 2 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221 		JBrowse link
G Plcb3 phospholipase C beta 3 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583 		JBrowse link
G Plcb4 phospholipase C, beta 4 ISO RGD PMID:17524618 RGD:5131502 NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113 		JBrowse link
G Prkca protein kinase C, alpha ISO RGD PMID:19934406 RGD:5131489 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcb protein kinase C, beta ISO RGD PMID:19934406 RGD:5131489 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Prkcd protein kinase C, delta ISO RGD PMID:19934406 RGD:5131489 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkce protein kinase C, epsilon ISO RGD PMID:19934406 RGD:5131489 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkcg protein kinase C, gamma ISO RGD PMID:19934406 RGD:5131489 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Prkch protein kinase C, eta ISO
IMP 		RGD PMID:19934406 PMID:9677361 RGD:5131489, RGD:5131657 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477 		JBrowse link
G Prkci protein kinase C, iota ISO RGD PMID:19934406 PMID:16525119 RGD:5131489, RGD:5132275 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784 		JBrowse link
G Prkcq protein kinase C, theta ISO RGD PMID:19934406 RGD:5131489 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508 		JBrowse link
G Prkcz protein kinase C, zeta ISO
IMP 		RGD PMID:19934406 PMID:16525119 PMID:20570724 RGD:5131489, RGD:5132275, RGD:5131661 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Rack1 receptor for activated C kinase 1 ISO RGD PMID:18491053 RGD:5131491 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IMP RGD PMID:7588705 RGD:10002727 NCBI chr 2:17,593,136...17,676,707
Ensembl chr 2:17,593,136...17,676,161 		JBrowse link
the extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:22177953 RGD:5686410 NCBI chr  X:3,780,932...3,845,919
Ensembl chr  X:3,780,932...3,792,611 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IMP
ISO 		RGD PMID:16508002 PMID:22177953 PMID:17310240 RGD:1580106, RGD:5686410, RGD:1626216 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:20445128 RGD:4892084 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IDA
ISO 		RGD PMID:12388314 PMID:22177953 RGD:628557, RGD:5686410 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Ksr1 kinase suppressor of ras 1 ISO RGD PMID:17726577 PMID:22177953 RGD:2293880, RGD:5686410 NCBI chr10:64,459,786...64,596,083
Ensembl chr10:64,459,786...64,596,082 		JBrowse link
G Ksr2 kinase suppressor of ras 2 ISO RGD PMID:22177953 RGD:5686410 NCBI chr12:44,462,579...44,848,555
Ensembl chr12:44,471,038...44,848,308 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 TAS
IMP 		RGD PMID:9779826 PMID:17310240 RGD:70317, RGD:1626216 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 NAS
IMP 		RGD PMID:8462694 PMID:17310240 RGD:729046, RGD:1626216 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISS
ISO 		RGD PMID:12835716 PMID:9305638 RGD:1357969, RGD:2293879 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 NAS RGD PMID:11359865 RGD:724475 NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA
IMP 		RGD PMID:12097495 PMID:16955078 PMID:17310240 RGD:628468, RGD:8553011, RGD:1626216 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA
ISO
IMP 		RGD PMID:12097495 PMID:20080775 PMID:16955078 PMID:17310240 RGD:628468, RGD:5508172, RGD:8553011, RGD:1626216 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO
IMP 		RGD PMID:16421520 PMID:16955078 RGD:2315047, RGD:8553011 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:134,554,943...134,594,393 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 TAS
IMP 		RGD PMID:17126425 PMID:10490027 RGD:2293882, RGD:2302807 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780 		JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:12790799 RGD:1642529 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15096502 RGD:1642630 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase TAS
ISO
IMP 		RGD PMID:9779826 PMID:22177953 PMID:17310240 PMID:16508002 RGD:70317, RGD:5686410, RGD:1626216, RGD:1580106 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:213,451,026...213,461,982
Ensembl chr 1:213,451,027...213,461,982 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:80,537,723...80,638,910
Ensembl chr  X:80,537,723...80,692,148 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IMP RGD PMID:14711826 RGD:1304283 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G Shc1 SHC adaptor protein 1 IEP RGD PMID:16699171 RGD:1643182 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Smad1 SMAD family member 1 IMP RGD PMID:16427075 RGD:1643230 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Tsc2 TSC complex subunit 2 ISO RGD PMID:15150271 RGD:1580097 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      kinase mediated signaling pathway 602
        altered kinase mediated signaling pathway + 13
        serine/threonine-specific kinase mediated signaling pathway + 476
        tyrosine-specific protein kinase mediated signaling pathway + 143
paths to the root