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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:chemical compound signaling pathway
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Accession:PW:0001162 term browser browse the term
Definition:The signaling pathway initiated by a chemical entity. It could be an organic or inorganic molecule.

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acetylcholine signaling pathway via muscarinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chrNW_004936543:856,678...862,080
Ensembl chrNW_004936543:856,676...862,109 		JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:653,654...702,433
Ensembl chrNW_004936728:654,638...700,213 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19478075 RGD:8549592 NCBI chrNW_004936486:8,720,036...8,830,472
Ensembl chrNW_004936486:8,720,036...8,831,075 		JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004936638:1,065,866...1,068,649
Ensembl chrNW_004936638:1,065,832...1,069,247 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004937238:101,948...109,513
Ensembl chrNW_004937238:102,061...109,474 		JBrowse link
G Rgs6 regulator of G protein signaling 6 ISO RGD PMID:22685433 RGD:8549594 NCBI chrNW_004936488:1,336,075...1,924,635
Ensembl chrNW_004936488:1,361,310...1,921,353 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:703,688...706,317
Ensembl chrNW_004936728:704,290...705,885 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936729:1,511,648...1,534,042
Ensembl chrNW_004936729:1,511,836...1,536,200 		JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm2 cholinergic receptor muscarinic 2 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936592:1,396,939...1,525,255
Ensembl chrNW_004936592:1,521,547...1,522,947 		JBrowse link
G Chrm4 cholinergic receptor muscarinic 4 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936562:2,685,209...2,687,751
Ensembl chrNW_004936562:2,493,774...2,689,731 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936810:353,405...435,087
Ensembl chrNW_004936810:353,067...438,337 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936529:1,779,582...1,801,251
Ensembl chrNW_004936529:1,779,571...1,801,255 		JBrowse link
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor muscarinic 1 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936581:387,939...400,740
Ensembl chrNW_004936581:387,705...400,740 		JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936484:13,953,141...14,373,174
Ensembl chrNW_004936484:13,954,887...13,956,659 		JBrowse link
G Chrm5 cholinergic receptor muscarinic 5 ISO RGD PMID:23841840 RGD:8549585 NCBI chrNW_004936673:2,607,906...2,610,885
Ensembl chrNW_004936673:2,608,003...2,609,624 		JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936588:1,770,777...1,789,143
Ensembl chrNW_004936588:1,770,771...1,789,170 		JBrowse link
G LOC101971412 guanine nucleotide-binding protein subunit alpha-14 ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936503:12,860,296...13,056,880
Ensembl chrNW_004936503:12,859,715...13,056,244 		JBrowse link
G LOC101971998 guanine nucleotide-binding protein G(q) subunit alpha ISO RGD PMID:23759942 RGD:8549590 NCBI chrNW_004936503:13,098,517...13,276,106
Ensembl chrNW_004936503:13,099,558...13,276,152 		JBrowse link
acetylcholine signaling pathway via nicotinic acetylcholine receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) ISO RGD PMID:17786266 RGD:8549506 NCBI chrNW_004936543:856,678...862,080
Ensembl chrNW_004936543:856,676...862,109 		JBrowse link
G Agrn agrin ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936737:2,010,647...2,041,401
Ensembl chrNW_004936737:2,011,724...2,039,796 		JBrowse link
G Chat choline O-acetyltransferase ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:653,654...702,433
Ensembl chrNW_004936728:654,638...700,213 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit ISO RGD PMID:19126755 PMID:23032192 RGD:8549508 RGD:8549510 NCBI chrNW_004936509:4,452,382...4,470,658
Ensembl chrNW_004936509:4,452,616...4,470,658 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936498:1,224,123...1,230,640
Ensembl chrNW_004936498:1,225,636...1,230,884 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936675:327,501...334,493
Ensembl chrNW_004936675:327,501...334,581 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,427,598...36,447,903
Ensembl chrNW_004936471:36,427,495...36,457,758 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936514:10,680,893...10,695,859
Ensembl chrNW_004936514:10,680,859...10,695,865 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936785:17,588...28,565
Ensembl chrNW_004936785:18,147...27,409 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004937351:32,324...46,871
Ensembl chrNW_004937351:34,921...47,246 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936482:7,792,292...7,801,152
Ensembl chrNW_004936482:7,792,292...7,801,152 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit ISO RGD PMID:19126755 PMID:23032192 RGD:8549508 RGD:8549510 NCBI chrNW_004936595:727,907...735,783
Ensembl chrNW_004936595:727,980...735,783 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936580:4,165,255...4,179,285
Ensembl chrNW_004936580:4,166,619...4,186,443 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936785:46,076...72,529
Ensembl chrNW_004936785:46,796...72,640 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:19126755 RGD:8549510 NCBI chrNW_004936471:36,408,471...36,425,571
Ensembl chrNW_004936471:36,408,447...36,426,021 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit ISO RGD PMID:19126755 PMID:23032192 RGD:8549508 RGD:8549510 NCBI chrNW_004936525:4,560,293...4,568,431
Ensembl chrNW_004936525:4,561,507...4,568,409 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit ISO RGD PMID:19126755 PMID:23032192 RGD:8549508 RGD:8549510 NCBI chrNW_004936677:2,809,057...2,813,838
Ensembl chrNW_004936677:2,808,799...2,813,290 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO RGD PMID:19126755 PMID:23032192 RGD:8549508 RGD:8549510 NCBI chrNW_004936525:4,550,987...4,556,574
Ensembl chrNW_004936525:4,550,987...4,556,576 		JBrowse link
G Lrp4 LDL receptor related protein 4 ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936562:2,211,519...2,262,899
Ensembl chrNW_004936562:2,211,514...2,263,937 		JBrowse link
G Musk muscle associated receptor tyrosine kinase ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936559:2,387,019...2,486,685
Ensembl chrNW_004936559:2,387,027...2,486,552 		JBrowse link
G Rapsn receptor associated protein of the synapse ISO RGD PMID:23032192 RGD:8549508 NCBI chrNW_004936562:1,796,087...1,804,153
Ensembl chrNW_004936562:1,795,905...1,804,181 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936728:703,688...706,317
Ensembl chrNW_004936728:704,290...705,885 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO RGD PMID:23677775 RGD:8549504 NCBI chrNW_004936729:1,511,648...1,534,042
Ensembl chrNW_004936729:1,511,836...1,536,200 		JBrowse link
dopamine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin dependent kinase 5 ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936527:6,478,934...6,483,848
Ensembl chrNW_004936527:6,478,982...6,483,866 		JBrowse link
G Csnk1a1 casein kinase 1 alpha 1 ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936504:5,351,354...5,394,856
Ensembl chrNW_004936504:5,351,029...5,396,034 		JBrowse link
G Drd1 dopamine receptor D1 ISO heterodimer coupled to Galphaq RGD PMID:17314300 PMID:25671228 RGD:11041142 RGD:1625010 NCBI chrNW_004936609:790,647...795,187
Ensembl chrNW_004936609:792,276...793,613 		JBrowse link
G Drd2 dopamine receptor D2 ISO heterodimer coupled to Galphaq RGD PMID:12121979 PMID:16490190 PMID:17314300 PMID:25671228 RGD:11041142 RGD:1581445 RGD:1625010 RGD:1625068 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:16490190 RGD:1625068 NCBI chrNW_004936536:1,580,732...1,616,726
Ensembl chrNW_004936536:1,580,732...1,616,725 		JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:17314300 RGD:1625010 NCBI chrNW_004936888:468,334...471,254
Ensembl chrNW_004936888:468,403...471,205 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:25671228 RGD:11041142 NCBI chrNW_004936477:16,860,222...16,863,505
Ensembl chrNW_004936477:16,861,773...16,863,215 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936599:2,345,982...2,348,494
Ensembl chrNW_004936599:2,344,552...2,348,494 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936493:3,981,364...4,002,083
Ensembl chrNW_004936493:3,981,370...4,002,667 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936558:3,631,794...3,651,754
Ensembl chrNW_004936558:3,630,561...3,651,786 		JBrowse link
G Ppp1r1b protein phosphatase 1 regulatory inhibitor subunit 1B ISO RGD PMID:21303898 PMID:21927600 RGD:11041134 RGD:11041163 NCBI chrNW_004936490:14,822,246...14,831,337
Ensembl chrNW_004936490:14,822,213...14,831,349 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936647:1,031,118...1,055,961
Ensembl chrNW_004936647:1,031,119...1,055,149 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936792:622,105...633,800 JBrowse link
G Ppp2r3a protein phosphatase 2 regulatory subunit B''alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936529:8,885,803...9,034,217
Ensembl chrNW_004936529:8,920,243...9,033,865 		JBrowse link
G Ppp2r5d protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936476:16,922,204...16,945,400
Ensembl chrNW_004936476:16,923,254...16,941,430 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936521:5,576,705...5,614,738
Ensembl chrNW_004936521:5,575,996...5,615,370 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936555:6,216,202...6,283,012
Ensembl chrNW_004936555:6,236,464...6,283,012 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:21927600 RGD:11041163 NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636 		JBrowse link
G Ptpn5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936528:523,884...586,306
Ensembl chrNW_004936528:525,769...586,327 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483 		JBrowse link
dopamine signaling pathway via D1 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00308 NCBI chrNW_004936643:47,830...338,891
Ensembl chrNW_004936643:47,837...339,007 		JBrowse link
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chrNW_004936725:1,751,272...1,897,937
Ensembl chrNW_004936725:1,751,266...1,897,946 		JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936498:4,089,621...4,172,749
Ensembl chrNW_004936498:4,094,893...4,172,755 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520 		JBrowse link
G Drd1 dopamine receptor D1 ISO SMPDB
RGD		 PMID:21303898 RGD:11041134 SMP:00308 NCBI chrNW_004936609:790,647...795,187
Ensembl chrNW_004936609:792,276...793,613 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936477:16,860,222...16,863,505
Ensembl chrNW_004936477:16,861,773...16,863,215 		JBrowse link
G Gnal G protein subunit alpha L ISO RGD PMID:24144882 RGD:11041135 NCBI chrNW_004936626:372,893...460,884
Ensembl chrNW_004936626:373,433...460,788 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00308 NCBI chrNW_004936737:1,518,855...1,554,926
Ensembl chrNW_004936737:1,524,325...1,555,102 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00308 NCBI chrNW_004936591:3,860,668...3,983,305
Ensembl chrNW_004936591:3,977,507...3,980,065 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936657:425,902...522,331
Ensembl chrNW_004936657:426,787...521,198 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936486:8,720,036...8,830,472
Ensembl chrNW_004936486:8,720,036...8,831,075 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936597:1,706,671...1,722,370
Ensembl chrNW_004936597:1,706,665...1,722,370 		JBrowse link
G LOC101971027 neuroendocrine secretory protein 55 ISO SMPDB SMP:00308 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00308 NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636 		JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936638:1,065,866...1,068,649
Ensembl chrNW_004936638:1,065,832...1,069,247 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004937238:101,948...109,513
Ensembl chrNW_004937238:102,061...109,474 		JBrowse link
G Rgs7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936526:9,087,820...9,552,482
Ensembl chrNW_004936526:9,088,350...9,551,899 		JBrowse link
G Rgs7bp regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936480:4,466,355...4,565,322
Ensembl chrNW_004936480:4,470,819...4,565,069 		JBrowse link
G Rgs9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936541:7,472,195...7,525,220
Ensembl chrNW_004936541:7,458,539...7,525,220 		JBrowse link
dopamine signaling pathway via D2 family of receptors term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 ISO RGD PMID:26468202 RGD:11041137 NCBI chrNW_004936725:1,751,272...1,897,937
Ensembl chrNW_004936725:1,751,266...1,897,946 		JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936498:4,089,621...4,172,749
Ensembl chrNW_004936498:4,094,893...4,172,755 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936536:1,580,732...1,616,726
Ensembl chrNW_004936536:1,580,732...1,616,725 		JBrowse link
G Drd4 dopamine receptor D4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936888:468,334...471,254
Ensembl chrNW_004936888:468,403...471,205 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:24831693 RGD:11041136 NCBI chrNW_004936529:1,779,582...1,801,251
Ensembl chrNW_004936529:1,779,571...1,801,255 		JBrowse link
G Gnao1 G protein subunit alpha o1 ISO RGD PMID:24831693 RGD:11041136 NCBI chrNW_004936475:8,610,123...8,681,606
Ensembl chrNW_004936475:8,565,889...8,690,673 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:21303898 PMID:23940634 RGD:11041134 RGD:13792715 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936657:425,902...522,331
Ensembl chrNW_004936657:426,787...521,198 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936486:8,720,036...8,830,472
Ensembl chrNW_004936486:8,720,036...8,831,075 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936597:1,706,671...1,722,370
Ensembl chrNW_004936597:1,706,665...1,722,370 		JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936638:1,065,866...1,068,649
Ensembl chrNW_004936638:1,065,832...1,069,247 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004937238:101,948...109,513
Ensembl chrNW_004937238:102,061...109,474 		JBrowse link
G Rgs7 regulator of G protein signaling 7 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936526:9,087,820...9,552,482
Ensembl chrNW_004936526:9,088,350...9,551,899 		JBrowse link
G Rgs7bp regulator of G protein signaling 7 binding protein ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936480:4,466,355...4,565,322
Ensembl chrNW_004936480:4,470,819...4,565,069 		JBrowse link
G Rgs9 regulator of G protein signaling 9 ISO RGD PMID:21303898 RGD:11041134 NCBI chrNW_004936541:7,472,195...7,525,220
Ensembl chrNW_004936541:7,458,539...7,525,220 		JBrowse link
epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936486:4,400,467...4,401,588
Ensembl chrNW_004936486:4,399,915...4,403,149 		JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210 		JBrowse link
G Arrb1 arrestin beta 1 ISO RGD PMID:18268361 PMID:19229505 RGD:4140419 RGD:5135529 NCBI chrNW_004936498:4,089,621...4,172,749
Ensembl chrNW_004936498:4,094,893...4,172,755 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:18268361 PMID:19229505 RGD:4140419 RGD:5135529 NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391 RGD:5135529 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391 RGD:5135529 NCBI chrNW_004936486:8,720,036...8,830,472
Ensembl chrNW_004936486:8,720,036...8,831,075 		JBrowse link
G LOC101971027 neuroendocrine secretory protein 55 ISO RGD PMID:19110970 RGD:4140391 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Snx13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chrNW_004936546:4,127,333...4,270,107
Ensembl chrNW_004936546:4,127,227...4,270,473 		JBrowse link
histamine signaling pathway, immunological term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00335 NCBI chrNW_004936643:47,830...338,891
Ensembl chrNW_004936643:47,837...339,007 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00335 NCBI chrNW_004936631:3,721,307...3,785,346
Ensembl chrNW_004936631:3,721,313...3,780,892 		JBrowse link
G Esr1 estrogen receptor 1 ISO SMPDB SMP:00335 NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00335 NCBI chrNW_004936737:1,518,855...1,554,926
Ensembl chrNW_004936737:1,524,325...1,555,102 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00335 NCBI chrNW_004936591:3,860,668...3,983,305
Ensembl chrNW_004936591:3,977,507...3,980,065 		JBrowse link
G Hrh2 histamine receptor H2 ISO SMPDB SMP:00335 NCBI chrNW_004936609:624,446...664,049
Ensembl chrNW_004936609:622,311...664,084 		JBrowse link
G LOC101971027 neuroendocrine secretory protein 55 ISO SMPDB SMP:00335 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00335 NCBI chrNW_004936599:2,345,982...2,348,494
Ensembl chrNW_004936599:2,344,552...2,348,494 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00335 NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636 		JBrowse link
serotonin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 ISO RGD PMID:19095043 RGD:39939084 NCBI chrNW_004936754:1,288,891...1,293,555
Ensembl chrNW_004936754:1,288,912...1,293,427 		JBrowse link
serotonin signaling pathway via receptors engaging G alphas protein family term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936643:47,830...338,891
Ensembl chrNW_004936643:47,837...339,007 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936631:3,721,307...3,785,346
Ensembl chrNW_004936631:3,721,313...3,780,892 		JBrowse link
G Esr1 estrogen receptor 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936737:1,518,855...1,554,926
Ensembl chrNW_004936737:1,524,325...1,555,102 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936591:3,860,668...3,983,305
Ensembl chrNW_004936591:3,977,507...3,980,065 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO SMPDB SMP:00309 NCBI chrNW_004936504:6,146,974...6,306,000
Ensembl chrNW_004936504:6,146,974...6,265,631 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO SMPDB SMP:00312 NCBI chrNW_004936474:5,848,719...5,858,520
Ensembl chrNW_004936474:5,848,707...5,859,749 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO SMPDB SMP:00311 NCBI chrNW_004936601:3,569,626...3,626,782
Ensembl chrNW_004936601:3,569,544...3,626,797 		JBrowse link
G LOC101971027 neuroendocrine secretory protein 55 ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936599:2,345,982...2,348,494
Ensembl chrNW_004936599:2,344,552...2,348,494 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00309 SMP:00311 SMP:00312 NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3951
    signaling pathway 1895
      chemical compound signaling pathway 85
        acetylcholine signaling pathway + 39
        cannabinoid signaling pathway + 0
        dopamine signaling pathway + 41
        epinephrine signaling pathway + 8
        gasotransmitter mediated signaling pathway + 0
        histamine signaling pathway + 9
        melatonin signaling pathway 0
        norepinephrine signaling pathway + 0
        radical mediated signaling pathway + 0
        serotonin signaling pathway + 12
paths to the root