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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:calcium/calcium-mediated signaling pathway
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Accession:PW:0001140 term browser browse the term
Definition:Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: KEGG:04020

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calcium/calcium-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 TAS RGD PMID:19789383 RGD:7204695 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007
JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 TAS RGD PMID:19789383 RGD:7204695 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712
JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr16:84,368,538...84,464,187
Ensembl chr16:84,368,527...84,464,187
JBrowse link
G CABP1 calcium binding protein 1 TAS RGD PMID:20668007 RGD:7204681 NCBI chr12:120,640,626...120,680,866
Ensembl chr12:120,640,626...120,667,324
JBrowse link
G CABP2 calcium binding protein 2 TAS RGD PMID:20668007 RGD:7204681 NCBI chr11:67,518,912...67,523,446
Ensembl chr11:67,518,912...67,524,517
JBrowse link
G CABP4 calcium binding protein 4 TAS RGD PMID:20668007 RGD:7204681 NCBI chr11:67,452,403...67,461,752
Ensembl chr11:67,452,406...67,461,752
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A TAS RGD PMID:21746798 RGD:7204688 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B TAS RGD PMID:21746798 RGD:7204688 NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C TAS RGD PMID:21746798 RGD:7204688 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D TAS RGD PMID:21746798 RGD:7204688 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E TAS RGD PMID:21746798 RGD:7204688 NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F TAS RGD PMID:21746798 RGD:7204688 NCBI chr  X:49,205,063...49,233,340
Ensembl chr  X:49,205,063...49,233,371
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G TAS RGD PMID:21746798 RGD:7204688 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H TAS RGD PMID:21746798 RGD:7204688 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I TAS RGD PMID:21746798 RGD:7204688 NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735
JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S TAS RGD PMID:21746798 RGD:7204688 NCBI chr 1:201,039,512...201,112,426
Ensembl chr 1:201,039,512...201,112,451
JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 TAS RGD PMID:21746798 RGD:7204688 NCBI chr17:39,173,453...39,197,669
Ensembl chr17:39,173,453...39,197,702
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 TAS RGD PMID:21746798 RGD:7204688 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 TAS RGD PMID:21746798 RGD:7204688 NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 TAS RGD PMID:21746798 RGD:7204688 NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167
JBrowse link
G CALB1 calbindin 1 TAS RGD PMID:20943758 RGD:7204685 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
G CALB2 calbindin 2 TAS RGD PMID:20943758 RGD:7204685 NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436
JBrowse link
G CALM1 calmodulin 1 TAS RGD PMID:10884684 PMID:18083096 RGD:7204676, RGD:7204677 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 TAS RGD PMID:10884684 PMID:18083096 RGD:7204676, RGD:7204677 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921
JBrowse link
G CALM3 calmodulin 3 TAS RGD PMID:10884684 PMID:18083096 RGD:7204676, RGD:7204677 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CALR calreticulin TAS RGD PMID:20356453 RGD:7204686 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CASQ1 calsequestrin 1 TAS RGD PMID:20356453 RGD:7204686 NCBI chr 1:160,190,575...160,201,886
Ensembl chr 1:160,190,575...160,201,886
JBrowse link
G CASQ2 calsequestrin 2 TAS RGD PMID:20356453 RGD:7204686 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,698,038...115,793,195
JBrowse link
G CIMIP3 ciliary microtubule inner protein 3 TAS RGD PMID:20668007 RGD:7204681 NCBI chr 6:42,155,406...42,163,418
Ensembl chr 6:42,155,406...42,163,418
JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 TAS RGD PMID:22435804 RGD:7204690 NCBI chr 4:47,935,977...48,016,681
Ensembl chr 4:47,935,977...48,016,681
JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 TAS RGD PMID:22435804 RGD:7204690 NCBI chr  X:151,734,746...151,745,564
Ensembl chr  X:151,734,746...151,745,564
JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 TAS RGD PMID:22435804 RGD:7204690 NCBI chr 2:98,346,456...98,398,601
Ensembl chr 2:98,346,188...98,398,601
JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 TAS RGD PMID:22435804 RGD:7204690 NCBI chr11:6,234,793...6,244,976
Ensembl chr11:6,234,765...6,244,479
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 TAS RGD PMID:22435804 RGD:7204690 NCBI chr16:57,882,340...57,971,128
Ensembl chr16:57,882,340...57,971,128
JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 TAS RGD PMID:22435804 RGD:7204690 NCBI chr 8:86,574,179...86,743,634
Ensembl chr 8:86,553,977...86,743,675
JBrowse link
G GUCA1B guanylate cyclase activator 1B TAS RGD PMID:20668007 RGD:7204681 NCBI chr 6:42,183,284...42,194,956
Ensembl chr 6:42,183,284...42,194,956
JBrowse link
G GUCA2B guanylate cyclase activator 2B TAS RGD PMID:20668007 RGD:7204681 NCBI chr 1:42,153,410...42,155,820
Ensembl chr 1:42,153,410...42,155,820
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 TAS RGD PMID:19133301 RGD:7204693 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 TAS RGD PMID:19133301 RGD:7204693 NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 TAS RGD PMID:19133301 RGD:7204693 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
JBrowse link
G KCNIP1 potassium voltage-gated channel interacting protein 1 TAS RGD PMID:20668007 RGD:7204681 NCBI chr 5:170,353,487...170,736,632
Ensembl chr 5:170,353,487...170,736,632
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 TAS RGD PMID:20668007 RGD:7204681 NCBI chr10:101,825,974...101,843,800
Ensembl chr10:101,825,974...101,843,920
JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 TAS RGD PMID:20668007 RGD:7204681 NCBI chr 2:95,297,347...95,386,077
Ensembl chr 2:95,297,327...95,386,077
JBrowse link
G KCNIP4 potassium voltage-gated channel interacting protein 4 TAS RGD PMID:20668007 RGD:7204681 NCBI chr 4:20,728,606...21,948,772
Ensembl chr 4:20,728,606...21,948,772
JBrowse link
G KCNN1 potassium calcium-activated channel subfamily N member 1 TAS RGD PMID:21942705 RGD:7204683 NCBI chr19:17,951,290...18,000,085
Ensembl chr19:17,951,293...18,000,085
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 TAS RGD PMID:21942705 RGD:7204683 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KCNN3 potassium calcium-activated channel subfamily N member 3 TAS RGD PMID:21942705 RGD:7204683 NCBI chr 1:154,697,455...154,870,281
Ensembl chr 1:154,697,455...154,870,281
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 TAS RGD PMID:21942705 RGD:7204683 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 TAS RGD PMID:20716668 RGD:7204689 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
JBrowse link
G MCU mitochondrial calcium uniporter TAS RGD PMID:22850819 RGD:7204696 NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694
JBrowse link
G NCS1 neuronal calcium sensor 1 TAS RGD PMID:20668007 RGD:7204681 NCBI chr 9:130,172,404...130,237,303
Ensembl chr 9:130,172,404...130,237,303
JBrowse link
G OCM oncomodulin TAS RGD PMID:20943758 RGD:7204685 NCBI chr 7:5,859,718...5,886,363
Ensembl chr 7:5,879,827...5,886,363
JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 TAS RGD PMID:22914293 RGD:7204692 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218
JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 TAS RGD PMID:22914293 RGD:7204692 NCBI chr 7:102,433,575...102,456,825
Ensembl chr 7:102,433,106...102,456,825
JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 TAS RGD PMID:22914293 RGD:7204692 NCBI chr16:30,949,068...30,954,938
Ensembl chr16:30,949,068...30,956,461
JBrowse link
G PVALB parvalbumin TAS RGD PMID:20943758 RGD:7204685 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479
JBrowse link
G RCVRN recoverin TAS RGD PMID:20668007 RGD:7204681 NCBI chr17:9,896,320...9,905,271
Ensembl chr17:9,896,320...9,905,271
JBrowse link
G RYR1 ryanodine receptor 1 TAS RGD PMID:20961976 RGD:7204694 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
JBrowse link
G RYR2 ryanodine receptor 2 TAS RGD PMID:20961976 RGD:7204694 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G RYR3 ryanodine receptor 3 TAS RGD PMID:20961976 RGD:7204694 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121
JBrowse link
G S100A1 S100 calcium binding protein A1 IMP
ISO
TAS
RGD PMID:16129693 PMID:17964289 PMID:17964289 RGD:1579960, RGD:7204682, RGD:7204682 NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,039
JBrowse link
G S100A4 S100 calcium binding protein A4 TAS
ISO
RGD PMID:17964289 PMID:17964289 RGD:7204682, RGD:7204682 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136
JBrowse link
G S100B S100 calcium binding protein B TAS
ISO
RGD PMID:17964289 PMID:17964289 RGD:7204682, RGD:7204682 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208
JBrowse link
G S100G S100 calcium binding protein G TAS RGD PMID:20943758 RGD:7204685 NCBI chr  X:16,650,158...16,654,670
Ensembl chr  X:16,650,158...16,654,670
JBrowse link
G SLC24A1 solute carrier family 24 member 1 TAS RGD PMID:17716241 RGD:7204698 NCBI chr15:65,611,350...65,661,002
Ensembl chr15:65,611,366...65,660,995
JBrowse link
G SLC24A2 solute carrier family 24 member 2 TAS RGD PMID:17716241 RGD:7204698 NCBI chr 9:19,507,455...20,307,892
Ensembl chr 9:19,507,452...19,789,037
JBrowse link
G SLC24A3 solute carrier family 24 member 3 TAS RGD PMID:17716241 RGD:7204698 NCBI chr20:19,212,642...19,722,926
Ensembl chr20:19,212,642...19,722,926
JBrowse link
G SLC24A4 solute carrier family 24 member 4 TAS RGD PMID:17716241 RGD:7204698 NCBI chr14:92,322,581...92,501,481
Ensembl chr14:92,322,581...92,501,481
JBrowse link
G SLC24A5 solute carrier family 24 member 5 TAS RGD PMID:17716241 RGD:7204698 NCBI chr15:48,120,990...48,142,672
Ensembl chr15:48,120,990...48,142,672
JBrowse link
G SLC8A1 solute carrier family 8 member A1 TAS RGD PMID:17716241 RGD:7204698 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G SLC8A2 solute carrier family 8 member A2 TAS RGD PMID:17716241 RGD:7204698 NCBI chr19:47,428,017...47,471,893
Ensembl chr19:47,428,017...47,471,893
JBrowse link
G SLC8A3 solute carrier family 8 member A3 TAS RGD PMID:17716241 RGD:7204698 NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
JBrowse link
G SLC8B1 solute carrier family 8 member B1 TAS RGD PMID:22850819 RGD:7204696 NCBI chr12:113,298,771...113,335,109
Ensembl chr12:113,298,759...113,359,493
JBrowse link
G STIM1 stromal interaction molecule 1 TAS RGD PMID:22914293 RGD:7204692 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
JBrowse link
G STIM2 stromal interaction molecule 2 TAS RGD PMID:22914293 RGD:7204692 NCBI chr 4:26,860,841...27,025,381
Ensembl chr 4:26,857,601...27,025,381
JBrowse link
G SYT1 synaptotagmin 1 TAS
ISO
RGD PMID:15534041 PMID:11751925 RGD:7204679, RGD:2311146 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
JBrowse link
G SYT7 synaptotagmin 7 TAS RGD PMID:15534041 PMID:18713958 RGD:7204679, RGD:2311148 NCBI chr11:61,513,714...61,588,387
Ensembl chr11:61,513,714...61,581,148
JBrowse link
G SYT9 synaptotagmin 9 TAS
ISO
RGD PMID:18713958 PMID:11751925 RGD:2311148, RGD:2311146 NCBI chr11:7,238,778...7,469,043
Ensembl chr11:7,238,778...7,469,043
JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type TAS RGD PMID:17964289 RGD:7204682 NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041
JBrowse link
G TNNC2 troponin C2, fast skeletal type TAS
ISO
RGD PMID:17964289 PMID:17964289 RGD:7204682, RGD:7204682 NCBI chr20:45,823,214...45,833,306
Ensembl chr20:45,823,214...45,833,745
JBrowse link
G TPCN1 two pore segment channel 1 TAS RGD PMID:20018950 RGD:7204697 NCBI chr12:113,221,464...113,298,585
Ensembl chr12:113,221,050...113,298,585
JBrowse link
G TPCN2 two pore segment channel 2 TAS RGD PMID:20018950 RGD:7204697 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 TAS RGD PMID:20716668 RGD:7204689 NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 TAS RGD PMID:20716668 RGD:7204689 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
JBrowse link
calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFATC2 nuclear factor of activated T cells 2 TAS RGD PMID:15336966 RGD:1579951 NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 TAS RGD PMID:15336966 RGD:1579951 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259
JBrowse link
G NFATC4 nuclear factor of activated T cells 4 TAS RGD PMID:15336966 RGD:1579951 NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha TAS RGD PMID:15336966 RGD:1579951 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta TAS RGD PMID:15336966 RGD:1579951 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024
JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma TAS RGD PMID:15336966 RGD:1579951 NCBI chr 8:22,441,078...22,541,125
Ensembl chr 8:22,440,819...22,541,142
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha TAS RGD PMID:15336966 RGD:1579951 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta TAS RGD PMID:15336966 RGD:1579951 NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021
JBrowse link
G RCAN1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113
JBrowse link
calcium signaling pathway via the calcium-sensing receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 IDA
ISO
RGD PMID:15637145 PMID:22192592 RGD:7207060, RGD:7207059 NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705
JBrowse link
G ARRB2 arrestin beta 2 IDA
ISO
RGD PMID:15637145 PMID:22192592 RGD:7207060, RGD:7207059 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:22192592 PMID:12239094 PMID:15637145 RGD:7207059, RGD:7207227, RGD:7207060 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G FLNA filamin A IMP RGD PMID:12239094 RGD:7207227 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 IDA RGD PMID:15637145 RGD:7207060 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 IDA RGD PMID:15637145 RGD:7207060 NCBI chr22:25,564,675...25,729,294
Ensembl chr22:25,564,675...25,729,294
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 IDA RGD PMID:15637145 RGD:7207060 NCBI chr 4:2,963,571...3,040,760
Ensembl chr 4:2,963,571...3,040,760
JBrowse link
G RGS12 regulator of G protein signaling 12 TAS RGD PMID:12239094 RGD:7207227 NCBI chr 4:3,285,891...3,439,913
Ensembl chr 4:3,293,021...3,439,913
JBrowse link
G RGS2 regulator of G protein signaling 2 IEP RGD PMID:12239094 RGD:7207227 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275
JBrowse link
G RGS4 regulator of G protein signaling 4 IEP RGD PMID:12239094 RGD:7207227 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
JBrowse link
G RGS5 regulator of G protein signaling 5 IEP RGD PMID:21393447 RGD:7207228 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791
JBrowse link
G RHOA ras homolog family member A IMP RGD PMID:12239094 RGD:7207227 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C TAS RGD PMID:23091085 RGD:7240708 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 TAS RGD PMID:23091085 RGD:7240708 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 TAS RGD PMID:22334212 RGD:7240704 NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
JBrowse link
G CALM1 calmodulin 1 TAS RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 TAS RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921
JBrowse link
G CALM3 calmodulin 3 TAS RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha TAS RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta TAS RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta TAS RGD PMID:22717267 PMID:23091085 RGD:7240705, RGD:7240708 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma TAS RGD PMID:22717267 RGD:7240705 NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 TAS RGD PMID:21070840 PMID:21301225 RGD:7240706, RGD:7240707 NCBI chr 1:20,482,391...20,486,210
Ensembl chr 1:20,482,391...20,486,210
JBrowse link
G CAMK2N2 calcium/calmodulin dependent protein kinase II inhibitor 2 TAS RGD PMID:21070840 PMID:21301225 RGD:7240706, RGD:7240707 NCBI chr 3:184,259,213...184,261,553
Ensembl chr 3:184,259,213...184,261,553
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 TAS RGD PMID:22717267 RGD:7240705 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 TAS RGD PMID:22334212 RGD:7240704 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 TAS RGD PMID:22717267 RGD:7240705 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A TAS RGD PMID:22717267 RGD:7240705 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B TAS RGD PMID:22334212 PMID:22717267 RGD:7240704, RGD:7240705 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G HDAC4 histone deacetylase 4 TAS RGD PMID:21255680 RGD:7241019 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G HDAC5 histone deacetylase 5 TAS RGD PMID:21255680 RGD:7241019 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702
JBrowse link
G LRRC7 leucine rich repeat containing 7 TAS RGD PMID:22717267 RGD:7240705 NCBI chr 1:69,567,922...70,144,364
Ensembl chr 1:69,567,922...70,151,945
JBrowse link
G PLN phospholamban TAS RGD PMID:23091085 RGD:7240708 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E TAS RGD PMID:18454172 RGD:7241020 NCBI chr17:58,755,854...58,985,179
Ensembl chr17:58,755,854...58,985,179
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F TAS RGD PMID:18454172 RGD:7241020 NCBI chr22:21,919,425...21,952,848
Ensembl chr22:21,919,425...21,952,848
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma TAS RGD PMID:18454172 RGD:7241020 NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha TAS RGD PMID:18454172 RGD:7241020 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073
JBrowse link
G RYR2 ryanodine receptor 2 TAS RGD PMID:23091085 RGD:7240708 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 TAS RGD PMID:23091085 RGD:7240708 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,743
JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 TAS RGD PMID:22717267 RGD:7240705 NCBI chr 6:33,418,167...33,453,689
Ensembl chr 6:33,419,661...33,453,689
JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDNRB endothelin receptor type B ISO RGD PMID:15245872 RGD:1581866 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    signaling pathway 2493
      calcium/calcium-mediated signaling pathway 134
        altered calcium/calcium-mediated signaling pathway + 0
        calcium signaling pathway via the calcium-sensing receptor + 12
        calcium/calmodulin dependent signaling pathway + 38
        muscle contraction pathway + 0
Path 2
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3600
      homeostasis pathway 1667
        inorganic chemical homeostasis pathway 293
          metal homeostasis pathway 201
            calcium homeostasis pathway 139
              calcium/calcium-mediated signaling pathway 134
                altered calcium/calcium-mediated signaling pathway + 0
                calcium signaling pathway via the calcium-sensing receptor + 12
                calcium/calmodulin dependent signaling pathway + 38
                muscle contraction pathway + 0
paths to the root