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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:calcium/calcium-mediated signaling pathway
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Accession:PW:0001140 term browser browse the term
Definition:Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: KEGG:04020

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calcium/calcium-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 5:26,165,370...26,196,517
Ensembl chr 5:26,164,205...26,193,172
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr16:3,405,871...3,443,339
Ensembl chr16:3,405,820...3,443,275
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr11:84,985,957...85,053,923
Ensembl chr11:84,989,169...85,103,957
JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr22:46,360,306...46,742,446
Ensembl chr22:46,368,243...46,662,220
JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr  X:127,966,366...128,013,900
Ensembl chr  X:127,966,492...128,013,901
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 ISO RGD PMID:19789383 RGD:7204695 NCBI chr25:25,602,857...25,716,385
Ensembl chr25:25,602,715...25,661,553
JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr15:59,189,075...59,348,684
Ensembl chr15:59,188,225...59,311,709
JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 5:69,771,909...69,861,030
Ensembl chr 5:69,801,818...69,860,576
JBrowse link
G CABP1 calcium binding protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr11:115,934,747...116,021,645 JBrowse link
G CABP2 calcium binding protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 1:6,741,202...6,744,931 JBrowse link
G CABP4 calcium binding protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 1:6,804,761...6,810,277
Ensembl chr 1:6,805,193...6,808,456
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO RGD PMID:21746798 RGD:7204688 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:21746798 RGD:7204688 NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:21746798 RGD:7204688 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:21746798 RGD:7204688 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO RGD PMID:21746798 RGD:7204688 NCBI chr25:47,589,859...47,924,081
Ensembl chr25:47,597,808...47,922,969
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F ISO RGD PMID:21746798 RGD:7204688 NCBI chr  X:46,304,831...46,330,562 JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO RGD PMID:21746798 RGD:7204688 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:21746798 RGD:7204688 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:21746798 RGD:7204688 NCBI chr19:22,129,795...22,264,485
Ensembl chr19:22,143,980...22,261,098
JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S ISO RGD PMID:21746798 RGD:7204688 NCBI chr25:28,288,483...28,363,231
Ensembl chr25:28,289,342...28,363,327
JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO RGD PMID:21746798 RGD:7204688 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:21746798 RGD:7204688 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:21746798 RGD:7204688 NCBI chr11:45,056,116...45,071,076
Ensembl chr11:45,061,046...45,071,544
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:21746798 RGD:7204688 NCBI chr10:37,240,749...37,518,174
Ensembl chr10:37,246,991...37,388,059
JBrowse link
G CALB1 calbindin 1 ISO RGD PMID:20943758 RGD:7204685 NCBI chr 8:85,135,956...85,160,806
Ensembl chr 8:85,137,528...85,160,855
JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:20943758 RGD:7204685 NCBI chr 5:54,503,635...54,538,304
Ensembl chr 5:54,504,082...54,538,441
JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180
JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951
JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr 6:39,957,012...39,966,562
Ensembl chr 6:39,957,320...39,966,581
Ensembl chr24:39,957,320...39,966,581
Ensembl chr14:39,957,320...39,966,581
JBrowse link
G CALR calreticulin ISO RGD PMID:20356453 RGD:7204686 NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792
JBrowse link
G CASQ1 calsequestrin 1 ISO RGD PMID:20356453 RGD:7204686 NCBI chr20:3,744,921...3,759,220
Ensembl chr20:3,744,780...3,756,435
JBrowse link
G CASQ2 calsequestrin 2 ISO RGD PMID:20356453 RGD:7204686 NCBI chr20:17,937,089...18,008,433
Ensembl chr20:17,937,524...18,008,786
JBrowse link
G CIMIP3 ciliary microtubule inner protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chr17:29,987,083...29,995,791 JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 ISO RGD PMID:22435804 RGD:7204690 NCBI chr  X:126,277,931...126,302,167
Ensembl chr  X:126,295,236...126,301,141
JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr14:2,039,281...2,124,527
Ensembl chr14:2,096,232...2,123,231
JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 1:58,581,702...58,592,733
Ensembl chr 1:58,582,175...58,588,376
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 5:43,814,500...43,903,323 JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 8:81,757,567...81,911,256
Ensembl chr 8:81,759,642...81,909,760
JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20668007 RGD:7204681 NCBI chr17:29,957,206...29,969,294
Ensembl chr17:29,957,508...29,967,922
JBrowse link
G GUCA2B guanylate cyclase activator 2B ISO RGD PMID:20668007 RGD:7204681 NCBI chr20:90,767,183...90,770,403
Ensembl chr20:90,767,609...90,770,198
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:19133301 RGD:7204693 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842
JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:19133301 RGD:7204693 NCBI chr11:26,089,480...26,574,621
Ensembl chr11:26,089,484...26,574,950
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 ISO RGD PMID:19133301 RGD:7204693 NCBI chr17:38,381,862...38,456,505
Ensembl chr17:38,381,743...38,456,499
JBrowse link
G KCNIP1 potassium voltage-gated channel interacting protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr23:72,555,329...72,934,425
Ensembl chr23:72,910,263...72,934,422
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312
JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chr14:329,142...420,937
Ensembl chr14:412,055...418,908
JBrowse link
G KCNIP4 potassium voltage-gated channel interacting protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr27:28,350,918...29,539,229
Ensembl chr27:29,420,010...29,541,783
JBrowse link
G KCNN1 potassium calcium-activated channel subfamily N member 1 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 6:16,440,908...16,470,613
Ensembl chr 6:16,448,038...16,472,319
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO RGD PMID:21942705 RGD:7204683 NCBI chr23:17,595,661...17,735,675
Ensembl chr23:17,598,177...17,735,669
JBrowse link
G KCNN3 potassium calcium-activated channel subfamily N member 3 ISO RGD PMID:21942705 RGD:7204683 NCBI chr20:8,961,833...9,124,728
Ensembl chr20:8,962,302...9,124,166
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 6:37,289,088...37,316,850 JBrowse link
G LOC103246137 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr27:2,273,540...2,313,083
Ensembl chr27:2,293,765...2,312,761
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 ISO RGD PMID:20716668 RGD:7204689 NCBI chr 6:7,019,132...7,030,675
Ensembl chr 6:7,019,277...7,030,474
JBrowse link
G MCU mitochondrial calcium uniporter ISO RGD PMID:22850819 RGD:7204696 NCBI chr 9:58,383,650...58,594,542
Ensembl chr 9:58,383,235...58,571,480
JBrowse link
G NCS1 neuronal calcium sensor 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr12:7,910,495...7,975,650 JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr11:116,997,375...117,012,115
Ensembl chr11:116,997,636...117,011,737
JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr28:10,775,456...10,788,670
Ensembl chr28:10,775,474...10,788,634
JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 5:27,637,919...27,644,585
Ensembl chr 5:27,638,731...27,644,829
JBrowse link
G PVALB parvalbumin ISO RGD PMID:20943758 RGD:7204685 NCBI chr19:19,501,100...19,520,031
Ensembl chr19:19,501,293...19,517,340
JBrowse link
G RCVRN recoverin ISO RGD PMID:20668007 RGD:7204681 NCBI chr16:9,236,647...9,246,994
Ensembl chr16:9,237,001...9,246,490
JBrowse link
G RYR1 ryanodine receptor 1 ISO RGD PMID:20961976 RGD:7204694 NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788
JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:20961976 RGD:7204694 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
G S100A1 S100 calcium binding protein A1 ISO RGD PMID:16129693 PMID:17964289 RGD:1579960 RGD:7204682 NCBI chr20:10,172,916...10,176,905 JBrowse link
G S100A4 S100 calcium binding protein A4 ISO RGD PMID:17964289 RGD:7204682 NCBI chr20:10,258,142...10,260,390
Ensembl chr20:10,258,070...10,260,871
JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:17964289 RGD:7204682 NCBI chr 2:90,188,820...90,194,986
Ensembl chr 2:90,188,639...90,195,023
JBrowse link
G S100G S100 calcium binding protein G ISO RGD PMID:20943758 RGD:7204685 NCBI chr  X:15,082,230...15,087,327
Ensembl chr  X:15,083,524...15,087,004
JBrowse link
G SLC24A1 solute carrier family 24 member 1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr26:17,924,872...17,969,413
Ensembl chr26:17,923,872...17,956,668
JBrowse link
G SLC24A2 solute carrier family 24 member 2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr12:59,962,744...60,229,539
Ensembl chr12:59,964,749...60,224,816
JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 2:48,238,872...48,736,517 JBrowse link
G SLC24A4 solute carrier family 24 member 4 ISO RGD PMID:17716241 RGD:7204698 NCBI chr24:70,068,924...70,242,148
Ensembl chr24:70,179,850...70,239,517
JBrowse link
G SLC24A5 solute carrier family 24 member 5 ISO RGD PMID:17716241 RGD:7204698 NCBI chr26:35,143,004...35,164,134
Ensembl chr26:35,143,097...35,163,718
JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SLC8A2 solute carrier family 8 member A2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 6:40,758,106...40,803,277
Ensembl chr 6:40,757,440...40,797,126
JBrowse link
G SLC8A3 solute carrier family 8 member A3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr24:47,287,487...47,428,608
Ensembl chr24:47,288,256...47,427,776
JBrowse link
G SLC8B1 solute carrier family 8 member B1 ISO RGD PMID:22850819 RGD:7204696 NCBI chr11:108,553,545...108,590,017
Ensembl chr11:108,553,794...108,589,533
JBrowse link
G STIM1 stromal interaction molecule 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 1:62,651,472...62,865,992
Ensembl chr 1:62,651,290...62,865,986
JBrowse link
G STIM2 stromal interaction molecule 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr27:23,330,382...23,498,965
Ensembl chr27:23,332,789...23,498,829
JBrowse link
G SYT1 synaptotagmin 1 ISO RGD PMID:11751925 PMID:15534041 RGD:2311146 RGD:7204679 NCBI chr11:74,442,890...75,032,756
Ensembl chr11:74,795,207...75,032,915
JBrowse link
G SYT7 synaptotagmin 7 ISO RGD PMID:15534041 PMID:18713958 RGD:2311148 RGD:7204679 NCBI chr 1:12,267,591...12,333,181
Ensembl chr 1:12,267,685...12,333,185
JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:11751925 PMID:18713958 RGD:2311146 RGD:2311148 NCBI chr 1:57,375,933...57,587,370
Ensembl chr 1:57,376,232...57,587,368
JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO RGD PMID:17964289 RGD:7204682 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518
JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO RGD PMID:17964289 RGD:7204682 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971
JBrowse link
G TPCN1 two pore segment channel 1 ISO RGD PMID:20018950 RGD:7204697 NCBI chr11:108,459,754...108,549,933
Ensembl chr11:108,475,380...108,552,374
JBrowse link
G TPCN2 two pore segment channel 2 ISO RGD PMID:20018950 RGD:7204697 NCBI chr 1:5,491,476...5,529,015
Ensembl chr 1:5,490,910...5,528,718
JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 ISO RGD PMID:20716668 RGD:7204689 NCBI chr21:111,787,214...111,816,893
Ensembl chr21:111,787,694...111,811,847
JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 ISO RGD PMID:20716668 RGD:7204689 NCBI chr21:111,750,821...111,766,274
Ensembl chr21:111,750,945...111,765,450
JBrowse link
calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFATC2 nuclear factor of activated T cells 2 ISO RGD PMID:15336966 RGD:1579951 NCBI chr 2:12,412,935...12,585,275
Ensembl chr 2:12,430,744...12,540,131
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 ISO RGD PMID:15336966 RGD:1579951 NCBI chr 5:59,193,139...59,346,361 JBrowse link
G NFATC4 nuclear factor of activated T cells 4 ISO RGD PMID:15336966 RGD:1579951 NCBI chr24:1,352,173...1,362,150
Ensembl chr24:1,352,291...1,362,680
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr 7:49,149,044...49,478,796
Ensembl chr 7:49,148,933...49,321,013
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr 9:57,782,256...57,841,307
Ensembl chr 9:57,782,304...57,844,573
JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:15336966 RGD:1579951 NCBI chr 8:20,522,829...20,621,445 JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr14:38,832,976...38,907,425
Ensembl chr14:38,832,809...38,905,321
JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr12:37,838,156...37,841,477 JBrowse link
G RCAN1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chr 2:78,561,212...78,658,023
Ensembl chr 2:78,562,795...78,571,498
JBrowse link
calcium signaling pathway via the calcium-sensing receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385
JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:12239094 PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 RGD:7207227 NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756
JBrowse link
G FLNA filamin A ISO RGD PMID:12239094 RGD:7207227 NCBI chr  X:128,657,580...128,683,812
Ensembl chr  X:128,657,393...128,680,531
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:15637145 RGD:7207060 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:15637145 RGD:7207060 NCBI chr19:8,438,543...8,601,652
Ensembl chr19:8,438,380...8,600,359
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15637145 RGD:7207060 NCBI chr27:45,691,936...45,765,334 JBrowse link
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:12239094 RGD:7207227 NCBI chr27:45,302,193...45,444,012 JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:12239094 RGD:7207227 NCBI chr25:36,620,047...36,623,367
Ensembl chr25:36,619,140...36,623,308
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:12239094 RGD:7207227 NCBI chr25:65,729,344...65,735,278
Ensembl chr25:65,726,394...65,735,381
JBrowse link
G RGS5 regulator of G protein signaling 5 ISO RGD PMID:21393447 RGD:7207228 NCBI chr25:65,608,384...65,667,811
Ensembl chr25:65,608,303...65,662,772
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:12239094 RGD:7207227 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704
JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:23091085 RGD:7240708 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:22334212 RGD:7240704 NCBI chr19:19,263,950...19,406,952
Ensembl chr19:19,267,426...19,406,883
JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180
JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951
JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr 6:39,957,012...39,966,562
Ensembl chr 6:39,957,320...39,966,581
Ensembl chr24:39,957,320...39,966,581
Ensembl chr14:39,957,320...39,966,581
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr23:52,829,438...52,899,428
Ensembl chr23:52,829,350...52,899,375
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr21:14,342,751...14,451,274
Ensembl chr21:14,342,892...14,451,282
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr 7:61,240,584...61,552,562 JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma ISO RGD PMID:22717267 RGD:7240705 NCBI chr 9:57,498,384...57,559,724
Ensembl chr 9:57,498,429...57,559,811
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256
JBrowse link
G CAMK2N2 calcium/calmodulin dependent protein kinase II inhibitor 2 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chr15:5,163,379...5,165,676
Ensembl chr15:5,163,600...5,164,731
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:22334212 RGD:7240704 NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:22717267 RGD:7240705 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202
JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:21255680 RGD:7241019 NCBI chr10:125,098,375...125,450,524
Ensembl chr10:125,098,366...125,403,227
JBrowse link
G HDAC5 histone deacetylase 5 ISO RGD PMID:21255680 RGD:7241019 NCBI chr16:62,267,837...62,314,914
Ensembl chr16:62,274,041...62,315,094
JBrowse link
G LRRC7 leucine rich repeat containing 7 ISO RGD PMID:22717267 RGD:7240705 NCBI chr20:63,016,441...63,567,809
Ensembl chr20:63,018,105...63,565,817
JBrowse link
G PLN phospholamban ISO RGD PMID:23091085 RGD:7240708 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481
JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E ISO RGD PMID:18454172 RGD:7241020 NCBI chr16:34,433,918...34,647,076 JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F ISO RGD PMID:18454172 RGD:7241020 NCBI chr19:4,167,925...4,200,550
Ensembl chr19:4,167,908...4,200,953
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:18454172 RGD:7241020 NCBI chr11:105,962,182...105,986,114 JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18454172 RGD:7241020 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280
JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:23091085 RGD:7240708 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457
JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr17:38,612,777...38,646,382
Ensembl chr17:38,617,679...38,646,192
JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDNRB endothelin receptor type B ISO RGD PMID:15245872 RGD:1581866 NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    signaling pathway 1919
      calcium/calcium-mediated signaling pathway 132
        altered calcium/calcium-mediated signaling pathway + 0
        calcium signaling pathway via the calcium-sensing receptor + 12
        calcium/calmodulin dependent signaling pathway + 38
        muscle contraction pathway + 0
Path 2
Term Annotations click to browse term
  pathway 4028
    regulatory pathway 2488
      homeostasis pathway 1295
        inorganic chemical homeostasis pathway 287
          metal homeostasis pathway 197
            calcium homeostasis pathway 137
              calcium/calcium-mediated signaling pathway 132
                altered calcium/calcium-mediated signaling pathway + 0
                calcium signaling pathway via the calcium-sensing receptor + 12
                calcium/calmodulin dependent signaling pathway + 38
                muscle contraction pathway + 0
paths to the root