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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:calcium/calcium-mediated signaling pathway
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Accession:PW:0001140 term browser browse the term
Definition:Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: KEGG:04020
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show annotations for term's descendants           Sort by:
calcium/calcium-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 6:18,384,981...18,400,038
Ensembl chr 6:18,385,007...18,400,036 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr26:8,148,181...8,209,392
Ensembl chr26:8,148,236...8,209,388 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 9:47,694,494...47,727,017
Ensembl chr 9:47,695,809...47,727,778 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr15:30,547,009...30,674,094
Ensembl chr15:30,547,015...30,616,429 		JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr20:7,665,468...8,037,407
Ensembl chr20:7,749,807...8,034,474 		JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr  X:121,355,217...121,405,245
Ensembl chr  X:121,361,239...121,403,609 		JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 ISO RGD PMID:19789383 RGD:7204695 NCBI chr38:321,246...420,262
Ensembl chr38:366,656...416,952 		JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr23:28,097,831...28,233,675
Ensembl chr23:28,066,639...28,235,215 		JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 5:67,986,120...68,046,391
Ensembl chr 5:67,986,355...68,046,272 		JBrowse link
G CABP1 calcium binding protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr26:16,492,484...16,523,265 JBrowse link
G CABP2 calcium binding protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr18:49,960,656...49,963,889
Ensembl chr18:49,959,544...49,964,268 		JBrowse link
G CABP4 calcium binding protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr18:50,014,698...50,017,854
Ensembl chr18:50,014,698...50,017,854 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO RGD PMID:21746798 RGD:7204688 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:21746798 RGD:7204688 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:21746798 RGD:7204688 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:21746798 RGD:7204688 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO RGD PMID:21746798 RGD:7204688 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F ISO RGD PMID:21746798 RGD:7204688 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO RGD PMID:21746798 RGD:7204688 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:21746798 RGD:7204688 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:21746798 RGD:7204688 NCBI chr10:25,381,446...25,493,680
Ensembl chr10:25,380,943...25,482,852 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S ISO RGD PMID:21746798 RGD:7204688 NCBI chr 7:2,108,716...2,172,246
Ensembl chr 7:2,108,455...2,303,220 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO RGD PMID:21746798 RGD:7204688 NCBI chr 9:23,182,407...23,197,035
Ensembl chr 9:23,180,554...23,195,673 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:21746798 RGD:7204688 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:21746798 RGD:7204688 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:21746798 RGD:7204688 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
G CALB1 calbindin 1 ISO RGD PMID:20943758 RGD:7204685 NCBI chr29:35,551,836...35,572,985
Ensembl chr29:35,552,436...35,572,925 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:20943758 RGD:7204685 NCBI chr 5:77,178,158...77,205,663
Ensembl chr 5:77,177,951...77,205,671 		JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr 8:61,398,231...61,408,874
Ensembl chr 8:61,398,244...61,406,195 		JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457 		JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391 		JBrowse link
G CALR calreticulin ISO RGD PMID:20356453 RGD:7204686 NCBI chr20:49,251,390...49,255,291
Ensembl chr20:49,251,777...49,255,245 		JBrowse link
G CASQ1 calsequestrin 1 ISO RGD PMID:20356453 RGD:7204686 NCBI chr38:22,012,060...22,020,430
Ensembl chr38:22,011,060...22,020,383 		JBrowse link
G CASQ2 calsequestrin 2 ISO RGD PMID:20356453 RGD:7204686 NCBI chr17:53,233,966...53,299,093
Ensembl chr17:53,224,438...53,299,708 		JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr13:43,831,159...43,864,276
Ensembl chr13:43,831,163...43,864,276 		JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 ISO RGD PMID:22435804 RGD:7204690 NCBI chr  X:119,695,898...119,702,791
Ensembl chr  X:119,695,898...119,702,446 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr10:44,232,716...44,278,555
Ensembl chr10:44,234,004...44,260,746 		JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 ISO RGD PMID:22435804 RGD:7204690 NCBI chr21:29,575,140...29,581,721
Ensembl chr21:29,575,578...29,580,616 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 2:58,574,552...58,641,631
Ensembl chr 2:58,574,552...58,640,812 		JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr29:32,744,946...32,992,715
Ensembl chr29:32,749,389...32,893,077 		JBrowse link
G GUCA1A guanylate cyclase activator 1A ISO RGD PMID:20668007 RGD:7204681 NCBI chr12:10,786,284...10,795,974
Ensembl chr12:10,788,424...10,795,442 		JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20668007 RGD:7204681 NCBI chr12:10,796,961...10,806,796
Ensembl chr12:10,797,921...10,834,237 		JBrowse link
G GUCA2B guanylate cyclase activator 2B ISO RGD PMID:20668007 RGD:7204681 NCBI chr15:1,094,283...1,096,605
Ensembl chr15:1,094,276...1,096,688 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:19133301 RGD:7204693 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:19133301 RGD:7204693 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 ISO RGD PMID:19133301 RGD:7204693 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
G KCNIP1 potassium voltage-gated channel interacting protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 4:41,220,128...41,566,841
Ensembl chr 4:41,223,369...41,431,510 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr28:14,409,526...14,425,641
Ensembl chr28:14,409,526...14,425,641 		JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chr17:34,725,433...34,808,429 JBrowse link
G KCNIP4 potassium voltage-gated channel interacting protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 3:88,013,222...88,896,093
Ensembl chr 3:87,771,875...88,894,884 		JBrowse link
G KCNN1 potassium calcium-activated channel subfamily N member 1 ISO RGD PMID:21942705 RGD:7204683 NCBI chr20:44,939,619...44,971,923
Ensembl chr20:44,939,603...44,969,020 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO RGD PMID:21942705 RGD:7204683 NCBI chr11:4,279,362...4,423,080
Ensembl chr11:4,154,746...4,423,078 		JBrowse link
G KCNN3 potassium calcium-activated channel subfamily N member 3 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 7:42,562,500...42,704,862
Ensembl chr 7:42,572,432...42,698,047 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 ISO RGD PMID:20716668 RGD:7204689 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MCU mitochondrial calcium uniporter ISO RGD PMID:22850819 RGD:7204696 NCBI chr 4:23,309,376...23,508,480
Ensembl chr 4:23,309,391...23,506,586 		JBrowse link
G NCS1 neuronal calcium sensor 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 9:53,661,361...53,676,925
Ensembl chr 9:53,672,910...53,676,910 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr26:7,584,276...7,599,667
Ensembl chr26:7,584,880...7,599,401 		JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 6:7,725,901...7,738,477
Ensembl chr 6:7,728,505...7,737,962 		JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 6:17,248,900...17,253,935
Ensembl chr 6:17,248,884...17,274,850 		JBrowse link
G PVALB parvalbumin ISO RGD PMID:20943758 RGD:7204685 NCBI chr10:27,655,896...27,674,309
Ensembl chr10:27,655,905...27,707,332 		JBrowse link
G RCVRN recoverin ISO RGD PMID:20668007 RGD:7204681 NCBI chr 5:34,323,580...34,330,667
Ensembl chr 5:34,323,576...34,330,667 		JBrowse link
G RYR1 ryanodine receptor 1 ISO RGD PMID:20961976 RGD:7204694 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:20961976 RGD:7204694 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 ISO RGD PMID:20961976 RGD:7204694 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
G S100A1 S100 calcium binding protein A1 ISO RGD PMID:16129693 PMID:17964289 RGD:1579960 RGD:7204682 NCBI chr 7:43,428,819...43,432,637
Ensembl chr 7:43,428,820...43,433,459 		JBrowse link
G S100A4 S100 calcium binding protein A4 ISO RGD PMID:17964289 RGD:7204682 NCBI chr 7:43,494,007...43,496,021 JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:17964289 RGD:7204682 NCBI chr31:39,783,990...39,788,289
Ensembl chr31:39,784,506...39,788,183 		JBrowse link
G S100G S100 calcium binding protein G ISO RGD PMID:20943758 RGD:7204685 NCBI chr  X:12,808,234...12,813,696
Ensembl chr  X:12,808,718...12,812,972 		JBrowse link
G SLC24A1 solute carrier family 24 member 1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr30:29,967,762...29,996,762
Ensembl chr30:29,967,762...29,995,005 		JBrowse link
G SLC24A2 solute carrier family 24 member 2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr11:39,273,285...39,521,223
Ensembl chr11:39,278,370...39,519,222 		JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr24:3,593,562...4,014,366
Ensembl chr24:3,593,513...3,784,467 		JBrowse link
G SLC24A4 solute carrier family 24 member 4 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 8:1,570,833...1,685,135
Ensembl chr 8:1,517,560...1,680,208 		JBrowse link
G SLC24A5 solute carrier family 24 member 5 ISO RGD PMID:17716241 RGD:7204698 NCBI chr30:14,372,019...14,400,262
Ensembl chr30:14,371,778...14,400,152 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700 		JBrowse link
G SLC8A2 solute carrier family 8 member A2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 1:108,544,825...108,575,894
Ensembl chr 1:108,544,509...108,575,891 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 8:43,780,363...43,926,142
Ensembl chr 8:43,781,120...43,926,343 		JBrowse link
G SLC8B1 solute carrier family 8 member B1 ISO RGD PMID:22850819 RGD:7204696 NCBI chr26:10,662,491...10,688,182
Ensembl chr26:10,662,208...10,687,629 		JBrowse link
G STIM1 stromal interaction molecule 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr21:26,394,592...26,594,764
Ensembl chr21:26,394,811...26,593,375 		JBrowse link
G STIM2 stromal interaction molecule 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 3:83,560,690...83,703,978
Ensembl chr 3:83,564,108...83,724,520 		JBrowse link
G SYT1 synaptotagmin 1 ISO RGD PMID:11751925 PMID:15534041 RGD:2311146 RGD:7204679 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732 		JBrowse link
G SYT7 synaptotagmin 7 ISO RGD PMID:15534041 PMID:18713958 RGD:2311148 RGD:7204679 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367 		JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:11751925 PMID:18713958 RGD:2311146 RGD:2311148 NCBI chr21:30,985,059...31,123,986
Ensembl chr21:30,986,521...31,162,414 		JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO RGD PMID:17964289 RGD:7204682 NCBI chr20:37,313,983...37,317,288
Ensembl chr20:37,311,966...37,317,321 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO RGD PMID:17964289 RGD:7204682 NCBI chr24:33,136,644...33,139,289
Ensembl chr24:33,128,290...33,163,050 		JBrowse link
G TPCN1 two pore segment channel 1 ISO RGD PMID:20018950 RGD:7204697 NCBI chr26:10,599,898...10,662,269
Ensembl chr26:10,599,780...10,660,767 		JBrowse link
G TPCN2 two pore segment channel 2 ISO RGD PMID:20018950 RGD:7204697 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 ISO RGD PMID:20716668 RGD:7204689 NCBI chr16:6,647,070...6,678,080
Ensembl chr16:6,650,574...6,676,963 		JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 ISO RGD PMID:20716668 RGD:7204689 NCBI chr16:6,691,521...6,706,205
Ensembl chr16:6,691,254...6,706,207 		JBrowse link
calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFATC2 nuclear factor of activated T cells 2 ISO RGD PMID:15336966 RGD:1579951 NCBI chr24:37,606,977...37,734,813
Ensembl chr24:37,609,561...37,771,132 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 ISO RGD PMID:15336966 RGD:1579951 NCBI chr 5:81,294,656...81,434,256
Ensembl chr 5:81,296,214...81,434,250 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 ISO RGD PMID:15336966 RGD:1579951 NCBI chr 8:4,337,098...4,346,409
Ensembl chr 8:4,336,450...4,346,100 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr 4:23,976,023...24,028,139
Ensembl chr 4:23,977,317...24,028,153 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:15336966 RGD:1579951 NCBI chr25:34,732,268...34,839,743
Ensembl chr25:34,725,226...34,838,994 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr10:67,242,552...67,308,469
Ensembl chr10:67,244,329...67,275,487 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr11:58,295,237...58,295,942 JBrowse link
G RCAN1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chr31:29,908,046...30,002,412
Ensembl chr31:29,909,388...30,002,418 		JBrowse link
calcium signaling pathway via the calcium-sensing receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:12239094 PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 RGD:7207227 NCBI chr33:25,340,822...25,432,814
Ensembl chr33:25,405,846...25,432,559 		JBrowse link
G FLNA filamin A ISO RGD PMID:12239094 RGD:7207227 NCBI chr  X:122,058,303...122,083,467
Ensembl chr  X:122,061,455...122,083,203 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:15637145 RGD:7207060 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:15637145 RGD:7207060 NCBI chr26:19,385,059...19,512,528
Ensembl chr26:19,385,058...19,516,077 		JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15637145 RGD:7207060 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290 		JBrowse link
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:12239094 RGD:7207227 NCBI chr 3:60,917,033...61,011,812
Ensembl chr 3:60,917,072...61,009,131 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:12239094 RGD:7207227 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:12239094 RGD:7207227 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190 		JBrowse link
G RGS5 regulator of G protein signaling 5 ISO RGD PMID:21393447 RGD:7207228 NCBI chr38:19,683,396...19,730,514
Ensembl chr38:19,683,485...19,725,778 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:12239094 RGD:7207227 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:23091085 RGD:7240708 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:22334212 RGD:7240704 NCBI chr10:27,750,314...27,862,646
Ensembl chr10:27,750,935...27,862,885 		JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr 8:61,398,231...61,408,874
Ensembl chr 8:61,398,244...61,406,195 		JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457 		JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr 4:58,800,818...58,865,830
Ensembl chr 4:58,800,813...58,865,830 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr32:33,223,093...33,525,783
Ensembl chr32:33,224,716...33,525,371 		JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma ISO RGD PMID:22717267 RGD:7240705 NCBI chr 4:24,244,063...24,299,362
Ensembl chr 4:24,245,960...24,299,357 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707
G CAMK2N2 calcium/calmodulin dependent protein kinase II inhibitor 2 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chr34:17,149,064...17,151,371 JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547 		JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:22334212 RGD:7240704 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:22717267 RGD:7240705 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:21255680 RGD:7241019 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G HDAC5 histone deacetylase 5 ISO RGD PMID:21255680 RGD:7241019 NCBI chr 9:19,261,075...19,297,669
Ensembl chr 9:19,260,893...19,297,623 		JBrowse link
G LRRC7 leucine rich repeat containing 7 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 6:75,578,651...75,964,171
Ensembl chr 6:75,580,515...75,964,156 		JBrowse link
G PLN phospholamban ISO RGD PMID:23091085 RGD:7240708 NCBI chr 1:58,579,095...58,590,541
Ensembl chr 1:58,579,145...58,590,535 		JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E ISO RGD PMID:18454172 RGD:7241020 NCBI chr 9:33,350,379...33,560,523
Ensembl chr 9:33,350,614...33,560,272 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F ISO RGD PMID:18454172 RGD:7241020 NCBI chr26:31,162,810...31,193,586
Ensembl chr26:31,166,593...31,193,587 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:18454172 RGD:7241020 NCBI chr26:8,497,350...8,518,467
Ensembl chr26:8,495,067...8,518,675 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18454172 RGD:7241020 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:23091085 RGD:7240708 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr12:2,829,274...2,862,888
Ensembl chr12:2,829,306...2,851,432 		JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDNRB endothelin receptor type B ISO RGD PMID:15245872 RGD:1581866 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4046
    signaling pathway 1926
      calcium/calcium-mediated signaling pathway 133
        altered calcium/calcium-mediated signaling pathway + 0
        calcium signaling pathway via the calcium-sensing receptor + 12
        calcium/calmodulin dependent signaling pathway + 38
        muscle contraction pathway + 0
Path 2
Term Annotations click to browse term
  pathway 4046
    regulatory pathway 2499
      homeostasis pathway 1305
        inorganic chemical homeostasis pathway 291
          metal homeostasis pathway 199
            calcium homeostasis pathway 138
              calcium/calcium-mediated signaling pathway 133
                altered calcium/calcium-mediated signaling pathway + 0
                calcium signaling pathway via the calcium-sensing receptor + 12
                calcium/calmodulin dependent signaling pathway + 38
                muscle contraction pathway + 0
paths to the root