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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:calcium/calcium-mediated signaling pathway
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Accession:PW:0001140 term browser browse the term
Definition:Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: KEGG:04020
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calcium/calcium-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955493:6,559,995...6,578,461
Ensembl chrNW_004955493:6,559,995...6,578,461 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955467:12,911,679...12,941,322
Ensembl chrNW_004955467:12,911,679...12,941,924 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955405:26,872,379...26,932,270
Ensembl chrNW_004955405:26,872,379...26,932,703 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955561:1,727,935...1,851,907
Ensembl chrNW_004955561:1,727,935...1,851,907 		JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955580:286,092...332,657
Ensembl chrNW_004955580:269,100...333,471 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955406:39,552,034...39,645,694
Ensembl chrNW_004955406:39,552,019...39,645,694 		JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955501:7,382,657...7,519,789
Ensembl chrNW_004955501:7,383,150...7,519,988 		JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chrNW_004955541:47,803...95,074
Ensembl chrNW_004955541:47,768...94,878 		JBrowse link
G Cabp1 calcium binding protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955455:11,000,763...11,068,922 JBrowse link
G Cabp2 calcium binding protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955422:17,967,313...17,972,468
Ensembl chrNW_004955422:17,967,313...17,972,468 		JBrowse link
G Cabp4 calcium binding protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955422:18,023,639...18,028,845
Ensembl chrNW_004955422:18,023,639...18,028,845 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955415:32,182,536...32,457,511
Ensembl chrNW_004955415:32,183,442...32,400,595 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955513:5,654,915...5,823,094
Ensembl chrNW_004955513:5,654,238...5,824,386 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955454:4,573,647...5,199,046
Ensembl chrNW_004955454:4,490,923...5,198,506 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955430:3,450,151...3,796,983
Ensembl chrNW_004955430:3,268,953...3,794,592 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955406:20,356,564...20,824,679
Ensembl chrNW_004955406:20,510,954...20,816,678 		JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955543:692,035...717,364
Ensembl chrNW_004955543:692,035...717,364 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955451:11,136,885...11,194,321
Ensembl chrNW_004955451:11,137,214...11,194,036 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955442:16,047,965...16,108,862
Ensembl chrNW_004955442:16,045,895...16,108,862 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955413:25,440,533...25,538,367
Ensembl chrNW_004955413:25,453,703...25,535,530 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955406:37,201,180...37,263,328
Ensembl chrNW_004955406:37,201,180...37,263,371 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955451:14,041,848...14,059,740
Ensembl chrNW_004955451:14,038,668...14,059,848 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955429:9,642,725...9,966,175
Ensembl chrNW_004955429:9,644,053...9,966,175 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955500:7,676,331...7,685,174
Ensembl chrNW_004955500:7,672,828...7,687,420 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:21746798 RGD:7204688 NCBI chrNW_004955440:17,364,996...17,497,446
Ensembl chrNW_004955440:17,371,321...17,497,616 		JBrowse link
G Calb1 calbindin 1 ISO RGD PMID:20943758 RGD:7204685 NCBI chrNW_004955417:6,944,300...6,969,341
Ensembl chrNW_004955417:6,942,900...6,969,502 		JBrowse link
G Calb2 calbindin 2 ISO RGD PMID:20943758 RGD:7204685 NCBI chrNW_004955484:4,075,103...4,103,509
Ensembl chrNW_004955484:4,075,067...4,103,559 		JBrowse link
G Calm1 calmodulin 1 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chrNW_004955438:12,842,437...12,854,028
Ensembl chrNW_004955438:12,842,437...12,854,028 		JBrowse link
G Calm2 calmodulin 2 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chrNW_004955441:13,973,147...13,988,665 JBrowse link
G Calm3 calmodulin 3 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chrNW_004955574:672,441...680,924
Ensembl chrNW_004955574:672,300...680,924 		JBrowse link
G Calr calreticulin ISO RGD PMID:20356453 RGD:7204686 NCBI chrNW_004955415:31,985,147...31,989,372
Ensembl chrNW_004955415:31,985,147...31,989,372 		JBrowse link
G Casq1 calsequestrin 1 ISO RGD PMID:20356453 RGD:7204686 NCBI chrNW_004955468:11,967,678...11,978,836
Ensembl chrNW_004955468:11,967,678...11,978,836 		JBrowse link
G Casq2 calsequestrin 2 ISO RGD PMID:20356453 RGD:7204686 NCBI chrNW_004955435:18,941,975...18,996,027
Ensembl chrNW_004955435:18,941,936...18,996,200 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955443:615,061...649,693
Ensembl chrNW_004955443:639,096...649,606 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955498:7,250,514...7,257,701
Ensembl chrNW_004955498:7,250,514...7,257,701 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955470:4,884,054...4,907,151
Ensembl chrNW_004955470:4,884,309...4,906,902 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955414:21,977,996...21,986,349
Ensembl chrNW_004955414:21,977,996...21,986,441 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955433:15,467,042...15,556,471 JBrowse link
G Cngb3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chrNW_004955417:4,164,328...4,288,516
Ensembl chrNW_004955417:4,168,766...4,300,437 		JBrowse link
G Guca1b guanylate cyclase activator 1B ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955437:8,384,692...8,390,946
Ensembl chrNW_004955437:8,382,299...8,390,946 		JBrowse link
G Guca2b guanylate cyclase activator 2B ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955537:1,798,249...1,801,673
Ensembl chrNW_004955537:1,798,249...1,801,673 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:19133301 RGD:7204693 NCBI chrNW_004955413:21,289,673...21,719,610
Ensembl chrNW_004955413:21,291,110...21,719,303 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor type 3 ISO RGD PMID:19133301 RGD:7204693 NCBI chrNW_004955437:2,055,782...2,106,709
Ensembl chrNW_004955437:2,055,805...2,106,076 		JBrowse link
G Kcnip1 potassium voltage-gated channel interacting protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955408:23,299,192...23,662,395
Ensembl chrNW_004955408:23,437,358...23,662,533 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955485:8,468,117...8,472,220
Ensembl chrNW_004955485:8,467,207...8,470,950 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955470:3,545,434...3,613,288
Ensembl chrNW_004955470:3,545,172...3,613,296 		JBrowse link
G Kcnip4 potassium voltage-gated channel interacting protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955480:2,803,374...3,911,081
Ensembl chrNW_004955480:2,803,482...3,909,709 		JBrowse link
G Kcnn1 potassium calcium-activated channel subfamily N member 1 ISO RGD PMID:21942705 RGD:7204683 NCBI chrNW_004955524:3,323,188...3,344,321
Ensembl chrNW_004955524:3,322,551...3,344,346 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 ISO RGD PMID:21942705 RGD:7204683 NCBI chrNW_004955408:34,223,523...34,366,191
Ensembl chrNW_004955408:34,109,334...34,368,114 		JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 ISO RGD PMID:21942705 RGD:7204683 NCBI chrNW_004955545:1,212,240...1,374,189
Ensembl chrNW_004955545:1,216,650...1,374,270 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:21942705 RGD:7204683 NCBI chrNW_004955555:1,493,600...1,509,113
Ensembl chrNW_004955555:1,490,052...1,509,113 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 ISO RGD PMID:20716668 RGD:7204689 NCBI chrNW_004955563:1,703,408...1,712,908
Ensembl chrNW_004955563:1,703,416...1,745,996 		JBrowse link
G Mcu mitochondrial calcium uniporter ISO RGD PMID:22850819 RGD:7204696 NCBI chrNW_004955437:18,750,779...18,800,149
Ensembl chrNW_004955437:18,752,584...18,936,507 		JBrowse link
G Ncs1 neuronal calcium sensor 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955513:268,979...289,385 JBrowse link
G Ocm oncomodulin ISO RGD PMID:20943758 RGD:7204685 NCBI chrNW_004955460:13,876,279...13,880,643 JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chrNW_004955482:6,731,949...6,746,095
Ensembl chrNW_004955482:6,731,949...6,775,545 		JBrowse link
G Orai2 ORAI calcium release-activated calcium modulator 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chrNW_004955456:15,170,424...15,180,763
Ensembl chrNW_004955456:15,170,424...15,180,763 		JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 ISO RGD PMID:22914293 RGD:7204692 NCBI chrNW_004955493:7,799,738...7,806,590
Ensembl chrNW_004955493:7,799,738...7,806,590 		JBrowse link
G Pvalb parvalbumin ISO RGD PMID:20943758 RGD:7204685 NCBI chrNW_004955413:23,329,467...23,345,487
Ensembl chrNW_004955413:23,329,467...23,345,487 		JBrowse link
G Rcvrn recoverin ISO RGD PMID:20668007 RGD:7204681 NCBI chrNW_004955467:7,220,237...7,236,450
Ensembl chrNW_004955467:7,220,237...7,236,450 		JBrowse link
G Ryr1 ryanodine receptor 1 ISO RGD PMID:20961976 RGD:7204694 NCBI chrNW_004955468:879,807...1,000,118
Ensembl chrNW_004955468:879,951...1,000,036 		JBrowse link
G Ryr2 ryanodine receptor 2 ISO RGD PMID:20961976 RGD:7204694 NCBI chrNW_004955492:2,647,597...3,275,512
Ensembl chrNW_004955492:2,648,956...3,076,509 		JBrowse link
G Ryr3 ryanodine receptor 3 ISO RGD PMID:20961976 RGD:7204694 NCBI chrNW_004955416:712,506...1,260,111
Ensembl chrNW_004955416:713,373...1,259,885 		JBrowse link
G S100a1 S100 calcium binding protein A1 ISO RGD PMID:16129693 PMID:17964289 RGD:1579960 RGD:7204682 NCBI chrNW_004955545:276,868...281,015
Ensembl chrNW_004955545:276,868...281,015 		JBrowse link
G S100a4 S100 calcium binding protein A4 ISO RGD PMID:17964289 RGD:7204682 NCBI chrNW_004955545:192,236...194,468
Ensembl chrNW_004955545:192,116...195,394 		JBrowse link
G S100b S100 calcium binding protein B ISO RGD PMID:17964289 RGD:7204682 NCBI chrNW_004955407:42,972,584...42,980,510
Ensembl chrNW_004955407:42,972,584...42,980,510 		JBrowse link
G S100g S100 calcium binding protein G ISO RGD PMID:20943758 RGD:7204685 NCBI chrNW_004955519:1,623,695...1,625,164
Ensembl chrNW_004955519:1,622,522...1,625,164 		JBrowse link
G Slc24a1 solute carrier family 24 member 1 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955450:9,850,170...9,881,172
Ensembl chrNW_004955450:9,856,718...9,881,172 		JBrowse link
G Slc24a2 solute carrier family 24 member 2 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955434:21,871,319...22,091,125
Ensembl chrNW_004955434:21,873,091...22,091,177 		JBrowse link
G Slc24a3 solute carrier family 24 member 3 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955415:27,477,801...27,930,108
Ensembl chrNW_004955415:27,477,819...27,928,383 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955438:14,609,779...14,765,516
Ensembl chrNW_004955438:14,609,424...14,759,673 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955409:5,747,624...5,768,122
Ensembl chrNW_004955409:5,747,624...5,768,122 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955441:7,653,107...8,037,784
Ensembl chrNW_004955441:7,656,031...7,957,640 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955574:1,290,907...1,315,399
Ensembl chrNW_004955574:1,288,952...1,315,401 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 ISO RGD PMID:17716241 RGD:7204698 NCBI chrNW_004955466:220,346...359,627
Ensembl chrNW_004955466:220,099...360,851 		JBrowse link
G Slc8b1 solute carrier family 8 member B1 ISO RGD PMID:22850819 RGD:7204696 NCBI chrNW_004955482:9,594,872...9,617,136
Ensembl chrNW_004955482:9,595,604...9,605,271 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chrNW_004955414:19,652,990...19,849,353
Ensembl chrNW_004955414:19,652,990...19,847,964 		JBrowse link
G Stim2 stromal interaction molecule 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chrNW_004955443:18,281,245...18,424,750
Ensembl chrNW_004955443:18,278,464...18,366,522 		JBrowse link
G Syt1 synaptotagmin 1 ISO RGD PMID:11751925 PMID:15534041 RGD:2311146 RGD:7204679 NCBI chrNW_004955405:17,840,012...18,372,156
Ensembl chrNW_004955405:17,839,884...18,372,566 		JBrowse link
G Syt7 synaptotagmin 7 ISO RGD PMID:15534041 PMID:18713958 RGD:2311148 RGD:7204679 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651 		JBrowse link
G Syt9 synaptotagmin 9 ISO RGD PMID:11751925 PMID:18713958 RGD:2311146 RGD:2311148 NCBI chrNW_004955414:23,061,163...23,221,986
Ensembl chrNW_004955414:23,061,163...23,221,962 		JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type ISO RGD PMID:17964289 RGD:7204682 NCBI chrNW_004955430:2,438,644...2,441,596
Ensembl chrNW_004955430:2,434,874...2,441,596 		JBrowse link
G Tnnc2 troponin C2, fast skeletal type ISO RGD PMID:17964289 RGD:7204682 NCBI chrNW_004955445:11,466,579...11,469,123
Ensembl chrNW_004955445:11,466,579...11,469,123 		JBrowse link
G Tpcn1 two pore segment channel 1 ISO RGD PMID:20018950 RGD:7204697 NCBI chrNW_004955482:9,538,572...9,594,739
Ensembl chrNW_004955482:9,542,079...9,592,972 		JBrowse link
G Tpcn2 two pore segment channel 2 ISO RGD PMID:20018950 RGD:7204697 NCBI chrNW_004955422:16,899,730...16,923,962
Ensembl chrNW_004955422:16,900,239...16,923,978 		JBrowse link
G Trpv6 transient receptor potential cation channel subfamily V member 6 ISO RGD PMID:20716668 RGD:7204689 NCBI chrNW_004955494:820,801...835,931
Ensembl chrNW_004955494:818,643...836,126 		JBrowse link
calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfatc2 nuclear factor of activated T cells 2 ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955445:7,035,876...7,153,199
Ensembl chrNW_004955445:7,035,876...7,153,237 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955484:8,433,765...8,558,005
Ensembl chrNW_004955484:8,436,330...8,526,680 		JBrowse link
G Nfatc4 nuclear factor of activated T cells 4 ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955409:35,931,208...35,941,555
Ensembl chrNW_004955409:35,931,173...35,940,696 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955496:6,934,542...7,059,745
Ensembl chrNW_004955496:6,908,224...7,059,816 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955437:18,323,852...18,377,815
Ensembl chrNW_004955437:18,323,857...18,377,815 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955403:45,915,985...45,969,350
Ensembl chrNW_004955403:45,916,002...45,968,185 		JBrowse link
G Ppp3r1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955424:16,624,214...16,690,783
Ensembl chrNW_004955424:16,623,917...16,690,783 		JBrowse link
G Ppp3r2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:15336966 RGD:1579951 NCBI chrNW_004955419:24,252,772...24,253,730 JBrowse link
G Rcan1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chrNW_004955407:33,873,427...33,951,762
Ensembl chrNW_004955407:33,873,383...33,951,498 		JBrowse link
calcium signaling pathway via the calcium-sensing receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb1 arrestin beta 1 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chrNW_004955414:16,478,843...16,568,050
Ensembl chrNW_004955414:16,478,843...16,562,135 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Casr calcium sensing receptor ISO RGD PMID:12239094 PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 RGD:7207227 NCBI chrNW_004955427:21,486,608...21,574,017
Ensembl chrNW_004955427:21,486,427...21,575,210 		JBrowse link
G Flna filamin A ISO RGD PMID:12239094 RGD:7207227 NCBI chrNW_004955580:874,233...895,172
Ensembl chrNW_004955580:874,233...895,232 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:15637145 RGD:7207060 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO RGD PMID:15637145 RGD:7207060 NCBI chrNW_004955442:19,640,145...19,785,803
Ensembl chrNW_004955442:19,640,145...19,785,803 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO RGD PMID:15637145 RGD:7207060 NCBI chrNW_004955514:1,837,141...1,895,785
Ensembl chrNW_004955514:1,837,141...1,895,785 		JBrowse link
G Rgs12 regulator of G protein signaling 12 ISO RGD PMID:12239094 RGD:7207227 NCBI chrNW_004955514:2,081,575...2,154,414
Ensembl chrNW_004955514:2,088,354...2,154,191 		JBrowse link
G Rgs2 regulator of G protein signaling 2 ISO RGD PMID:12239094 RGD:7207227 NCBI chrNW_004955406:30,261,757...30,265,389
Ensembl chrNW_004955406:30,261,757...30,266,005 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:12239094 RGD:7207227 NCBI chrNW_004955462:13,340,812...13,347,598
Ensembl chrNW_004955462:13,338,960...13,347,610 		JBrowse link
G Rgs5 regulator of G protein signaling 5 ISO RGD PMID:21393447 RGD:7207228 NCBI chrNW_004955462:13,228,110...13,288,063
Ensembl chrNW_004955462:13,228,002...13,283,034 		JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:12239094 RGD:7207227 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:23091085 RGD:7240708 NCBI chrNW_004955454:4,573,647...5,199,046
Ensembl chrNW_004955454:4,490,923...5,198,506 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chrNW_004955429:9,642,725...9,966,175
Ensembl chrNW_004955429:9,644,053...9,966,175 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:22334212 RGD:7240704 NCBI chrNW_004955413:23,136,369...23,248,231
Ensembl chrNW_004955413:23,132,896...23,248,231 		JBrowse link
G Calm1 calmodulin 1 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chrNW_004955438:12,842,437...12,854,028
Ensembl chrNW_004955438:12,842,437...12,854,028 		JBrowse link
G Calm2 calmodulin 2 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chrNW_004955441:13,973,147...13,988,665 JBrowse link
G Calm3 calmodulin 3 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chrNW_004955574:672,441...680,924
Ensembl chrNW_004955574:672,300...680,924 		JBrowse link
G Camk2a calcium/calmodulin dependent protein kinase II alpha ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chrNW_004955415:4,247,307...4,307,402
Ensembl chrNW_004955415:4,247,014...4,307,458 		JBrowse link
G Camk2b calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chrNW_004955456:7,711,583...7,760,506
Ensembl chrNW_004955456:7,713,552...7,760,207 		JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chrNW_004955428:25,583,501...25,880,395 JBrowse link
G Camk2g calcium/calmodulin dependent protein kinase II gamma ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955437:18,036,614...18,089,876
Ensembl chrNW_004955437:18,036,046...18,087,408 		JBrowse link
G Camk2n1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chrNW_004955452:1,044,696...1,046,657
Ensembl chrNW_004955452:1,043,459...1,046,669 		JBrowse link
G Camk2n2 calcium/calmodulin dependent protein kinase II inhibitor 2 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chrNW_004955420:23,226,270...23,227,403
Ensembl chrNW_004955420:23,226,264...23,227,409 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955420:13,068,289...13,273,805
Ensembl chrNW_004955420:13,068,289...13,273,805 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:22334212 RGD:7240704 NCBI chrNW_004955408:7,912,223...8,226,241
Ensembl chrNW_004955408:7,912,592...8,223,570 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955513:5,154,864...5,178,636
Ensembl chrNW_004955513:5,154,864...5,178,636 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955442:8,171,114...8,565,187
Ensembl chrNW_004955442:8,174,232...8,562,059 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chrNW_004955413:10,358,931...10,780,004
Ensembl chrNW_004955413:10,376,597...10,779,145 		JBrowse link
G Hdac4 histone deacetylase 4 ISO RGD PMID:21255680 RGD:7241019 NCBI chrNW_004955542:1,629,691...1,886,160
Ensembl chrNW_004955542:1,629,691...1,886,210 		JBrowse link
G Hdac5 histone deacetylase 5 ISO RGD PMID:21255680 RGD:7241019 NCBI chrNW_004955451:17,223,217...17,246,451
Ensembl chrNW_004955451:17,223,287...17,244,051 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955423:21,764,046...22,269,590
Ensembl chrNW_004955423:21,769,366...22,269,781 		JBrowse link
G Pln phospholamban ISO RGD PMID:23091085 RGD:7240708 NCBI chrNW_004955436:1,439,098...1,447,070
Ensembl chrNW_004955436:1,439,098...1,447,070 		JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent 1E ISO RGD PMID:18454172 RGD:7241020 NCBI chrNW_004955451:3,989,575...4,137,400
Ensembl chrNW_004955451:3,986,715...4,137,134 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent 1F ISO RGD PMID:18454172 RGD:7241020 NCBI chrNW_004955442:17,233,258...17,256,009
Ensembl chrNW_004955442:17,227,723...17,252,383 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:18454172 RGD:7241020 NCBI chrNW_004955482:7,582,605...7,605,340
Ensembl chrNW_004955482:7,578,782...7,606,132 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18454172 RGD:7241020 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361 		JBrowse link
G Ryr2 ryanodine receptor 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chrNW_004955492:2,647,597...3,275,512
Ensembl chrNW_004955492:2,648,956...3,076,509 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:23091085 RGD:7240708 NCBI chrNW_004955427:25,295,517...25,371,419
Ensembl chrNW_004955427:25,295,514...25,371,552 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chrNW_004955437:1,950,559...1,981,004
Ensembl chrNW_004955437:1,950,602...1,979,251 		JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednrb endothelin receptor type B ISO RGD PMID:15245872 RGD:1581866 NCBI chrNW_004955404:29,394,253...29,425,358
Ensembl chrNW_004955404:29,394,164...29,425,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3924
    signaling pathway 1879
      calcium/calcium-mediated signaling pathway 131
        altered calcium/calcium-mediated signaling pathway + 0
        calcium signaling pathway via the calcium-sensing receptor + 12
        calcium/calmodulin dependent signaling pathway + 38
        muscle contraction pathway + 0
Path 2
Term Annotations click to browse term
  pathway 3924
    regulatory pathway 2432
      homeostasis pathway 1271
        inorganic chemical homeostasis pathway 289
          metal homeostasis pathway 197
            calcium homeostasis pathway 136
              calcium/calcium-mediated signaling pathway 131
                altered calcium/calcium-mediated signaling pathway + 0
                calcium signaling pathway via the calcium-sensing receptor + 12
                calcium/calmodulin dependent signaling pathway + 38
                muscle contraction pathway + 0
paths to the root