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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:calcium/calcium-mediated signaling pathway
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Accession:PW:0001140 term browser browse the term
Definition:Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: KEGG:04020

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calcium/calcium-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 Ensembl chr16:29,265,516...29,290,807
Ensembl chr16:29,265,516...29,290,807
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr17:3,992,088...4,013,998
Ensembl chr17:3,965,925...3,998,382
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr12:87,107,900...87,229,514
Ensembl chr12:90,427,560...90,495,320
JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 3:10,260,556...10,643,346
Ensembl chr 3:10,611,619...10,738,006
JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 ISO RGD PMID:19789383 RGD:7204695 NCBI chr  X:143,068,171...143,133,479
Ensembl chr  X:152,955,109...153,019,445
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 1:179,231,712...179,348,759
Ensembl chr 1:183,580,773...183,639,882
JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 ISO RGD PMID:19789383 RGD:7204695 NCBI chr 3:127,937,272...128,101,060
Ensembl chr 3:135,260,796...135,423,700
JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 ISO RGD PMID:19789383 RGD:7204695 NCBI chr16:65,033,470...65,127,403
Ensembl chr16:84,375,658...84,468,671
JBrowse link
G CABP1 calcium binding protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr12:118,224,046...118,250,696 JBrowse link
G CABP2 calcium binding protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr11:62,877,978...62,882,653 JBrowse link
G CABP4 calcium binding protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr11:62,813,477...62,820,425
Ensembl chr11:66,121,992...66,128,758
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO RGD PMID:21746798 RGD:7204688 NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:21746798 RGD:7204688 NCBI chr 9:108,989,621...109,256,841 JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:21746798 RGD:7204688 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:21746798 RGD:7204688 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO RGD PMID:21746798 RGD:7204688 NCBI chr 1:156,796,855...157,296,987
Ensembl chr 1:160,628,089...160,949,270
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F ISO RGD PMID:21746798 RGD:7204688 NCBI chr  X:41,504,804...41,533,501
Ensembl chr  X:49,356,994...49,385,678
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO RGD PMID:21746798 RGD:7204688 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:21746798 RGD:7204688 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:21746798 RGD:7204688 NCBI chr22:20,463,511...20,595,253
Ensembl chr22:38,296,436...38,414,963
JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S ISO RGD PMID:21746798 RGD:7204688 NCBI chr 1:176,639,189...176,712,171
Ensembl chr 1:180,941,836...181,014,823
JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO RGD PMID:21746798 RGD:7204688 NCBI chr17:18,073,818...18,098,400
Ensembl chr17:18,349,146...18,373,338
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:21746798 RGD:7204688 NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:21746798 RGD:7204688 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:21746798 RGD:7204688 NCBI chr2B:39,137,777...39,399,007
Ensembl chr2B:156,379,469...156,639,328
JBrowse link
G CALB1 calbindin 1 ISO RGD PMID:20943758 RGD:7204685 NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814
JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:20943758 RGD:7204685 NCBI chr16:53,620,317...53,653,372
Ensembl chr16:71,195,770...71,227,937
JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697
JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:10884684 PMID:18083096 RGD:7204676 RGD:7204677 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALR calreticulin ISO RGD PMID:20356453 RGD:7204686 NCBI chr19:12,501,013...12,506,909
Ensembl chr19:13,242,900...13,249,416
JBrowse link
G CASQ1 calsequestrin 1 ISO RGD PMID:20356453 RGD:7204686 NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969
JBrowse link
G CASQ2 calsequestrin 2 ISO RGD PMID:20356453 RGD:7204686 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311
JBrowse link
G CIMIP3 ciliary microtubule inner protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 6:41,743,396...41,751,883
Ensembl chr 6:43,045,307...43,053,377
JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 4:74,196,877...74,213,563
Ensembl chr 4:84,910,653...84,945,248
JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 ISO RGD PMID:22435804 RGD:7204690 NCBI chr  X:141,315,052...141,324,754
Ensembl chr  X:151,275,800...151,281,909
JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr2A:100,911,053...100,962,278
Ensembl chr2A:99,259,808...99,308,517
JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 ISO RGD PMID:22435804 RGD:7204690 NCBI chr11:6,368,768...6,378,976
Ensembl chr11:6,051,091...6,061,550
JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 ISO RGD PMID:22435804 RGD:7204690 NCBI chr16:38,160,056...38,249,474
Ensembl chr16:57,292,093...57,375,460
JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 ISO RGD PMID:22435804 RGD:7204690 NCBI chr 8:83,269,589...83,439,999
Ensembl chr 8:85,238,043...85,407,059
JBrowse link
G GUCA1B guanylate cyclase activator 1B ISO RGD PMID:20668007 RGD:7204681 NCBI chr 6:41,771,537...41,783,364
Ensembl chr 6:43,072,469...43,083,838
JBrowse link
G GUCA2B guanylate cyclase activator 2B ISO RGD PMID:20668007 RGD:7204681 NCBI chr 1:41,452,722...41,455,192
Ensembl chr 1:42,832,196...42,835,425
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:19133301 RGD:7204693 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811
JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:19133301 RGD:7204693 NCBI chr12:59,478,206...59,984,572
Ensembl chr12:62,092,241...62,596,018
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 ISO RGD PMID:19133301 RGD:7204693 NCBI chr 6:33,194,531...33,269,788
Ensembl chr 6:34,303,454...34,378,215
JBrowse link
G KCNIP1 potassium voltage-gated channel interacting protein 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 5:165,711,110...166,095,049
Ensembl chr 5:172,622,331...172,853,992
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO RGD PMID:20668007 RGD:7204681 NCBI chr10:98,428,619...98,446,581
Ensembl chr10:101,899,898...101,918,691
JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 ISO RGD PMID:20668007 RGD:7204681 NCBI chr2A:104,018,539...104,111,126
Ensembl chr2A:96,200,412...96,291,374
JBrowse link
G KCNIP4 potassium voltage-gated channel interacting protein 4 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 4:15,131,693...16,354,827
Ensembl chr 4:20,422,728...21,645,866
JBrowse link
G KCNN1 potassium calcium-activated channel subfamily N member 1 ISO RGD PMID:21942705 RGD:7204683 NCBI chr19:17,430,795...17,478,981
Ensembl chr19:18,422,231...18,458,630
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 5:109,722,916...109,862,747
Ensembl chr 5:115,522,443...115,661,079
JBrowse link
G KCNN3 potassium calcium-activated channel subfamily N member 3 ISO RGD PMID:21942705 RGD:7204683 NCBI chr 1:130,052,903...130,218,977
Ensembl chr 1:133,666,876...133,828,366
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:21942705 RGD:7204683 NCBI chr19:40,715,621...40,735,025
Ensembl chr19:49,321,403...49,335,900
JBrowse link
G LOC100987781 calcium release-activated calcium channel protein 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr12:119,229,069...119,243,435 JBrowse link
G LOC100990398 transient receptor potential cation channel subfamily V member 6 ISO RGD PMID:20716668 RGD:7204689 NCBI chr 7:134,862,223...134,877,051
Ensembl chr 7:147,353,684...147,368,475
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 ISO RGD PMID:20716668 RGD:7204689 NCBI chr19:6,813,498...6,825,153
Ensembl chr19:7,671,704...7,683,093
JBrowse link
G MCU mitochondrial calcium uniporter ISO RGD PMID:22850819 RGD:7204696 NCBI chr10:69,243,282...69,435,193
Ensembl chr10:71,845,335...71,898,545
JBrowse link
G NCS1 neuronal calcium sensor 1 ISO RGD PMID:20668007 RGD:7204681 NCBI chr 9:101,299,724...101,364,897
Ensembl chr 9:129,950,921...130,016,257
JBrowse link
G OCM oncomodulin ISO RGD PMID:20943758 RGD:7204685 NCBI chr 7:6,066,257...6,126,400 JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 7:94,573,923...94,592,028 JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 ISO RGD PMID:22914293 RGD:7204692 NCBI chr16:24,014,018...24,019,889
Ensembl chr16:31,314,922...31,323,320
JBrowse link
G PVALB parvalbumin ISO RGD PMID:20943758 RGD:7204685 NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316
JBrowse link
G RCVRN recoverin ISO RGD PMID:20668007 RGD:7204681 NCBI chr17:41,747,255...41,759,074
Ensembl chr17:46,490,605...46,502,962
JBrowse link
G RYR1 ryanodine receptor 1 ISO RGD PMID:20961976 RGD:7204694 NCBI chr19:35,527,466...35,685,446
Ensembl chr19:44,106,036...44,256,327
JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:20961976 RGD:7204694 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
G RYR3 ryanodine receptor 3 ISO RGD PMID:20961976 RGD:7204694 NCBI chr15:11,816,430...12,379,101
Ensembl chr15:30,817,428...31,214,494
JBrowse link
G S100A1 S100 calcium binding protein A1 ISO RGD PMID:16129693 PMID:17964289 RGD:1579960 RGD:7204682 NCBI chr 1:128,984,296...128,987,979 JBrowse link
G S100A4 S100 calcium binding protein A4 ISO RGD PMID:17964289 RGD:7204682 NCBI chr 1:128,898,765...128,901,042
Ensembl chr 1:132,527,846...132,530,122
JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:17964289 RGD:7204682 NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953
JBrowse link
G S100G S100 calcium binding protein G ISO RGD PMID:20943758 RGD:7204685 NCBI chr  X:9,272,311...9,276,147
Ensembl chr  X:16,642,211...16,645,760
JBrowse link
G SLC24A1 solute carrier family 24 member 1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr15:44,552,886...44,597,640
Ensembl chr15:62,831,987...62,882,431
JBrowse link
G SLC24A2 solute carrier family 24 member 2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr 9:19,317,132...19,593,503
Ensembl chr 9:19,814,244...20,249,225
JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr20:19,168,820...19,680,706
Ensembl chr20:19,137,938...19,646,475
JBrowse link
G SLC24A4 solute carrier family 24 member 4 ISO RGD PMID:17716241 RGD:7204698 NCBI chr14:72,956,230...73,128,851
Ensembl chr14:92,299,507...92,468,939
JBrowse link
G SLC24A5 solute carrier family 24 member 5 ISO RGD PMID:17716241 RGD:7204698 NCBI chr15:27,069,937...27,091,619
Ensembl chr15:45,394,090...45,415,823
JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO RGD PMID:17716241 RGD:7204698 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038
JBrowse link
G SLC8A2 solute carrier family 8 member A2 ISO RGD PMID:17716241 RGD:7204698 NCBI chr19:44,420,146...44,464,242
Ensembl chr19:53,077,857...53,113,830
JBrowse link
G SLC8A3 solute carrier family 8 member A3 ISO RGD PMID:17716241 RGD:7204698 NCBI chr14:50,634,091...50,779,712 JBrowse link
G SLC8B1 solute carrier family 8 member B1 ISO RGD PMID:22850819 RGD:7204696 NCBI chr12:110,903,215...110,936,908
Ensembl chr12:114,286,624...114,319,683
JBrowse link
G STIM1 stromal interaction molecule 1 ISO RGD PMID:22914293 RGD:7204692 NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224
JBrowse link
G STIM2 stromal interaction molecule 2 ISO RGD PMID:22914293 RGD:7204692 NCBI chr 4:21,262,272...21,424,944
Ensembl chr 4:26,537,703...26,694,416
JBrowse link
G SYT1 synaptotagmin 1 ISO RGD PMID:11751925 PMID:15534041 RGD:2311146 RGD:7204679 NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923
JBrowse link
G SYT7 synaptotagmin 7 ISO RGD PMID:15534041 PMID:18713958 RGD:2311148 RGD:7204679 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375
JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:11751925 PMID:18713958 RGD:2311146 RGD:2311148 NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187
JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO RGD PMID:17964289 RGD:7204682 NCBI chr 3:52,393,106...52,396,076
Ensembl chr 3:53,621,749...53,624,726
JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO RGD PMID:17964289 RGD:7204682 NCBI chr20:42,162,502...42,172,829
Ensembl chr20:43,249,725...43,254,134
JBrowse link
G TPCN1 two pore segment channel 1 ISO RGD PMID:20018950 RGD:7204697 NCBI chr12:110,812,587...110,903,033
Ensembl chr12:114,209,638...114,286,443
JBrowse link
G TPCN2 two pore segment channel 2 ISO RGD PMID:20018950 RGD:7204697 NCBI chr11:64,139,512...64,227,913
Ensembl chr11:67,438,635...67,478,106
JBrowse link
calcineurin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFATC2 nuclear factor of activated T cells 2 ISO RGD PMID:15336966 RGD:1579951 NCBI chr20:47,734,054...47,910,435
Ensembl chr20:48,858,238...49,034,007
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 ISO RGD PMID:15336966 RGD:1579951 NCBI chr16:48,456,144...48,603,306
Ensembl chr16:67,888,806...67,996,274
JBrowse link
G NFATC4 nuclear factor of activated T cells 4 ISO RGD PMID:15336966 RGD:1579951 NCBI chr14:5,141,699...5,156,021
Ensembl chr14:23,266,702...23,279,249
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752
JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma ISO RGD PMID:15336966 RGD:1579951 NCBI chr 8:21,690,598...21,791,335
Ensembl chr 8:18,629,261...18,729,995
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:15336966 RGD:1579951 NCBI chr2A:68,227,282...68,300,482 JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:15336966 RGD:1579951 NCBI chr 9:72,796,099...72,799,499 JBrowse link
G RCAN1 regulator of calcineurin 1 ISO RGD PMID:16415348 RGD:1581652 NCBI chr21:20,889,123...20,987,964
Ensembl chr21:34,258,355...34,267,025
JBrowse link
calcium signaling pathway via the calcium-sensing receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:12239094 PMID:15637145 PMID:22192592 RGD:7207059 RGD:7207060 RGD:7207227 NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268
JBrowse link
G FLNA filamin A ISO RGD PMID:12239094 RGD:7207227 NCBI chr  X:143,799,088...143,825,282 JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:15637145 RGD:7207060 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:15637145 RGD:7207060 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15637145 RGD:7207060 NCBI chr 4:3,106,064...3,181,270
Ensembl chr 4:3,008,126...3,083,094
JBrowse link
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:12239094 RGD:7207227 NCBI chr 4:3,439,030...3,589,026
Ensembl chr 4:3,444,570...3,573,712
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:12239094 RGD:7207227 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:12239094 RGD:7207227 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225
JBrowse link
G RGS5 regulator of G protein signaling 5 ISO RGD PMID:21393447 RGD:7207228 NCBI chr 1:138,561,940...138,622,698
Ensembl chr 1:142,362,663...142,387,291
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:12239094 RGD:7207227 NCBI chr 3:49,282,009...49,339,887 JBrowse link
calcium/calmodulin dependent kinase 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:23091085 RGD:7240708 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr10:18,459,528...18,862,495
Ensembl chr10:18,795,832...19,195,226
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:22334212 RGD:7240704 NCBI chr22:17,475,693...17,618,299
Ensembl chr22:35,317,121...35,454,850
JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697
JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr 5:145,644,164...145,714,143
Ensembl chr 5:151,649,062...151,719,373
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:22717267 PMID:23091085 RGD:7240705 RGD:7240708 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma ISO RGD PMID:22717267 RGD:7240705 NCBI chr10:70,335,474...70,397,617
Ensembl chr10:73,008,103...73,068,737
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600
JBrowse link
G CAMK2N2 calcium/calmodulin dependent protein kinase II inhibitor 2 ISO RGD PMID:21070840 PMID:21301225 RGD:7240706 RGD:7240707 NCBI chr 3:181,293,755...181,296,088 JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO RGD PMID:22334212 RGD:7240704 NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:22717267 RGD:7240705 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:22334212 PMID:22717267 RGD:7240704 RGD:7240705 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799
JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:21255680 RGD:7241019 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G HDAC5 histone deacetylase 5 ISO RGD PMID:21255680 RGD:7241019 NCBI chr17:13,273,052...13,319,695
Ensembl chr17:13,446,836...13,479,140
JBrowse link
G LRRC7 leucine rich repeat containing 7 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 1:68,802,557...69,359,159
Ensembl chr 1:70,794,254...71,343,917
JBrowse link
G PLN phospholamban ISO RGD PMID:23091085 RGD:7240708 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668
JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E ISO RGD PMID:18454172 RGD:7241020 NCBI chr17:52,832,291...53,057,157
Ensembl chr17:57,874,629...57,903,205
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F ISO RGD PMID:18454172 RGD:7241020 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO RGD PMID:18454172 RGD:7241020 NCBI chr12:108,288,158...108,311,128
Ensembl chr12:111,681,611...111,705,658
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18454172 RGD:7241020 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:23091085 RGD:7240708 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 ISO RGD PMID:22717267 RGD:7240705 NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490
JBrowse link
calcium/calmodulin dependent kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDNRB endothelin receptor type B ISO RGD PMID:15245872 RGD:1581866 NCBI chr13:59,112,349...59,136,615
Ensembl chr13:78,153,020...78,177,286
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4063
    signaling pathway 1929
      calcium/calcium-mediated signaling pathway 133
        altered calcium/calcium-mediated signaling pathway + 0
        calcium signaling pathway via the calcium-sensing receptor + 12
        calcium/calmodulin dependent signaling pathway + 38
        muscle contraction pathway + 0
Path 2
Term Annotations click to browse term
  pathway 4063
    regulatory pathway 2507
      homeostasis pathway 1306
        inorganic chemical homeostasis pathway 292
          metal homeostasis pathway 200
            calcium homeostasis pathway 138
              calcium/calcium-mediated signaling pathway 133
                altered calcium/calcium-mediated signaling pathway + 0
                calcium signaling pathway via the calcium-sensing receptor + 12
                calcium/calmodulin dependent signaling pathway + 38
                muscle contraction pathway + 0
paths to the root