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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:calcium transport pathway
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Accession:PW:0001139 term browser browse the term
Definition:Calcium is pumped into organelles or out of the cell by pumps and exchangers to maintain the low calcium concentration necessary for cell viability. Many type of channels, some calcium-selective, others of lower selectivity or calcium-permeant, allow for the flow of calcium from external sources or internal stores into the cell to initiate many signaling events. The movement of calcium ions, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Synonyms:related_synonym: calcium ion transport
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calcium transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 TAS RGD PMID:19789383 RGD:7204695 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,868...3,964,464 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007 		JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 TAS RGD PMID:19789383 RGD:7204695 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939 		JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081 		JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 TAS RGD PMID:19789383 RGD:7204695 NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712 		JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 TAS RGD PMID:19789383 RGD:7204695 NCBI chr16:84,368,538...84,464,187
Ensembl chr16:84,368,527...84,464,187 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A TAS RGD PMID:21746798 RGD:7204688 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B TAS RGD PMID:21746798 RGD:7204688 NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C TAS RGD PMID:21746798 RGD:7204688 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D TAS RGD PMID:21746798 RGD:7204688 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E TAS RGD PMID:21746798 RGD:7204688 NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F TAS RGD PMID:21746798 RGD:7204688 NCBI chr  X:49,205,063...49,233,340
Ensembl chr  X:49,205,063...49,233,371 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G TAS RGD PMID:21746798 RGD:7204688 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H TAS RGD PMID:21746798 RGD:7204688 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I TAS RGD PMID:21746798 RGD:7204688 NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S TAS RGD PMID:21746798 RGD:7204688 NCBI chr 1:201,039,512...201,112,426
Ensembl chr 1:201,039,512...201,112,451 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 TAS RGD PMID:21746798 RGD:7204688 NCBI chr17:39,173,453...39,197,669
Ensembl chr17:39,173,453...39,197,702 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 TAS RGD PMID:21746798 RGD:7204688 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 TAS RGD PMID:21746798 RGD:7204688 NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 TAS RGD PMID:21746798 RGD:7204688 NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167 		JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 TAS RGD PMID:12087135 RGD:6893549 NCBI chr 4:47,935,977...48,016,681
Ensembl chr 4:47,935,977...48,016,681 		JBrowse link
G CNGA2 cyclic nucleotide gated channel subunit alpha 2 TAS RGD PMID:12087135 RGD:6893549 NCBI chr  X:151,734,746...151,745,564
Ensembl chr  X:151,734,746...151,745,564 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 TAS RGD PMID:12087135 RGD:6893549 NCBI chr 2:98,346,456...98,398,601
Ensembl chr 2:98,346,188...98,398,601 		JBrowse link
G CNGA4 cyclic nucleotide gated channel subunit alpha 4 TAS RGD PMID:12087135 RGD:6893549 NCBI chr11:6,234,793...6,244,976
Ensembl chr11:6,234,765...6,244,479 		JBrowse link
G CNGB1 cyclic nucleotide gated channel subunit beta 1 TAS RGD PMID:12087135 RGD:6893549 NCBI chr16:57,882,340...57,971,128
Ensembl chr16:57,882,340...57,971,128 		JBrowse link
G CNGB3 cyclic nucleotide gated channel subunit beta 3 TAS RGD PMID:12087135 RGD:6893549 NCBI chr 8:86,574,179...86,743,634
Ensembl chr 8:86,553,977...86,743,675 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 TAS RGD PMID:19133301 RGD:7204693 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 TAS RGD PMID:19133301 RGD:7204693 NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 TAS RGD PMID:19133301 RGD:7204693 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 TAS RGD PMID:20716668 RGD:7204689 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009 		JBrowse link
G MCU mitochondrial calcium uniporter TAS RGD PMID:22850819 RGD:7204696 NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 TAS RGD PMID:22914293 RGD:7204692 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218 		JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 TAS RGD PMID:22914293 RGD:7204692 NCBI chr 7:102,433,575...102,456,825
Ensembl chr 7:102,433,106...102,456,825 		JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 TAS RGD PMID:22914293 RGD:7204692 NCBI chr16:30,949,068...30,954,938
Ensembl chr16:30,949,068...30,956,461 		JBrowse link
G RYR1 ryanodine receptor 1 TAS RGD PMID:20961976 RGD:7204694 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G RYR2 ryanodine receptor 2 TAS RGD PMID:20961976 RGD:7204694 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G RYR3 ryanodine receptor 3 TAS RGD PMID:20961976 RGD:7204694 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121 		JBrowse link
G SLC24A1 solute carrier family 24 member 1 TAS RGD PMID:17716241 RGD:7204698 NCBI chr15:65,611,350...65,661,002
Ensembl chr15:65,611,366...65,660,995 		JBrowse link
G SLC24A2 solute carrier family 24 member 2 TAS RGD PMID:17716241 RGD:7204698 NCBI chr 9:19,507,455...20,307,892
Ensembl chr 9:19,507,452...19,789,037 		JBrowse link
G SLC24A3 solute carrier family 24 member 3 TAS RGD PMID:17716241 RGD:7204698 NCBI chr20:19,212,642...19,722,926
Ensembl chr20:19,212,642...19,722,926 		JBrowse link
G SLC24A4 solute carrier family 24 member 4 TAS RGD PMID:17716241 RGD:7204698 NCBI chr14:92,322,581...92,501,481
Ensembl chr14:92,322,581...92,501,481 		JBrowse link
G SLC24A5 solute carrier family 24 member 5 TAS RGD PMID:17716241 RGD:7204698 NCBI chr15:48,120,990...48,142,672
Ensembl chr15:48,120,990...48,142,672 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 TAS RGD PMID:17716241 RGD:7204698 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SLC8A2 solute carrier family 8 member A2 TAS RGD PMID:17716241 RGD:7204698 NCBI chr19:47,428,017...47,471,893
Ensembl chr19:47,428,017...47,471,893 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 TAS RGD PMID:17716241 RGD:7204698 NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480 		JBrowse link
G SLC8B1 solute carrier family 8 member B1 TAS RGD PMID:22850819 RGD:7204696 NCBI chr12:113,298,771...113,335,109
Ensembl chr12:113,298,759...113,359,493 		JBrowse link
G STIM1 stromal interaction molecule 1 TAS RGD PMID:22914293 RGD:7204692 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G STIM2 stromal interaction molecule 2 TAS RGD PMID:22914293 RGD:7204692 NCBI chr 4:26,860,841...27,025,381
Ensembl chr 4:26,857,601...27,025,381 		JBrowse link
G TPCN1 two pore segment channel 1 TAS RGD PMID:20018950 RGD:7204697 NCBI chr12:113,221,464...113,298,585
Ensembl chr12:113,221,050...113,298,585 		JBrowse link
G TPCN2 two pore segment channel 2 TAS RGD PMID:20018950 RGD:7204697 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316 		JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 TAS RGD PMID:20716668 RGD:7204689 NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746 		JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 TAS RGD PMID:20716668 RGD:7204689 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3600
      transport pathway 355
        ion transport pathway 69
          metal ion transport pathway 69
            calcium transport pathway 55
Path 2
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3600
      homeostasis pathway 1667
        inorganic chemical homeostasis pathway 293
          metal homeostasis pathway 201
            calcium homeostasis pathway 139
              calcium transport pathway 55
paths to the root