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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:parathyroid hormone signaling pathway
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Accession:PW:0001135 term browser browse the term
Definition:Parathyroid hormone (PTH) signaling is important for calcium and phosphate homeostasis in bone and kidney. It acts to increase the concentration of calcium in the blood, has both anabolic and catabolic effects in the bone and regulates calcium and phosphate reabsorption in the kidney. It also plays important roles in vitamin D metabolism.
Synonyms:related_synonym: PTH signaling pathway
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parathyroid hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb1 arrestin beta 1 ISO RGD PMID:20703892 RGD:7207469 NCBI chrNW_004955414:16,478,843...16,568,050
Ensembl chrNW_004955414:16,478,843...16,562,135 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:20703892 RGD:7207469 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Ezr ezrin ISO RGD PMID:21777186 RGD:7207465 NCBI chrNW_004955439:3,701,722...3,740,345
Ensembl chrNW_004955439:3,703,013...3,740,345 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:19395963 RGD:7207470 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 ISO RGD PMID:21777186 RGD:7207465 NCBI chrNW_004955553:1,639,267...1,656,850
Ensembl chrNW_004955553:1,639,267...1,656,850 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 ISO RGD PMID:21777186 RGD:7207465 NCBI chrNW_004955442:15,224,214...15,235,372
Ensembl chrNW_004955442:15,224,214...15,235,379 		JBrowse link
G Pth parathyroid hormone ISO RGD PMID:9054374 PMID:19395963 PMID:21777186 RGD:7207455 RGD:7207465 RGD:7207470 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117 		JBrowse link
G Pth1r parathyroid hormone 1 receptor ISO RGD PMID:9054374 PMID:19395963 PMID:20703892 PMID:21777186 RGD:7207455 RGD:7207465 RGD:7207469 RGD:7207470 NCBI chrNW_004955420:25,274,269...25,291,984
Ensembl chrNW_004955420:25,273,431...25,296,471 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3930
    signaling pathway 1892
      hormone signaling pathway 368
        peptide and protein hormone signaling pathway 262
          parathyroid hormone family signaling pathway 8
            parathyroid hormone signaling pathway 8
Path 2
Term Annotations click to browse term
  pathway 3930
    regulatory pathway 2444
      homeostasis pathway 1271
        inorganic chemical homeostasis pathway 289
          metal homeostasis pathway 197
            calcium homeostasis pathway 136
              parathyroid hormone signaling pathway 8
paths to the root