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ONTOLOGY REPORT - ANNOTATIONS


Term:spliceosome pathway
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Accession:PW:0001073 term browser browse the term
Definition:The spliceosome is a multimegadalton ribonucleoprotein complex that removes the exons to produce the mature mRNA, including several mature mRNAs from a single RNA transcript via alternative splicing. A complex assembly/disassembly pathway mediates the two chemical steps of a splicing event. lncRNAs are also frequently spliced.
Synonyms:related_synonym: KEGG:03040

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spliceosome pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aar2 AAR2 splicing factor JBrowse link 3 152,626,738 152,648,365 RGD:9686090
G Acin1 apoptotic chromatin condensation inducer 1 JBrowse link 15 33,288,369 33,333,256 RGD:6907045
G Alyref Aly/REF export factor JBrowse link 10 109,768,593 109,774,639 RGD:6907045
G Aqr aquarius intron-binding spliceosomal factor JBrowse link 3 105,570,399 105,640,431 RGD:6907045
RGD:9686094
G Bcas2 BCAS2, pre-mRNA processing factor JBrowse link 2 205,662,633 205,670,514 RGD:6907045
RGD:9686094
G Bud31 BUD31 homolog JBrowse link 12 11,232,963 11,240,449 RGD:6907045
RGD:9686094
G Ccdc12 coiled-coil domain containing 12 JBrowse link 8 118,925,682 118,977,038 RGD:6907045
RGD:9686094
G Cdc40 cell division cycle 40 JBrowse link 20 48,503,973 48,574,546 RGD:6907045
G Cdc5l cell division cycle 5-like JBrowse link 9 17,949,764 17,988,514 RGD:6907045
RGD:9686094
G Cherp calcium homeostasis endoplasmic reticulum protein JBrowse link 16 19,068,783 19,081,837 RGD:6907045
G Crnkl1 crooked neck pre-mRNA splicing factor 1 JBrowse link 6 18,349,226 18,351,540 RGD:6907045
RGD:9686094
G Ctnnbl1 catenin, beta like 1 JBrowse link 3 154,212,245 154,373,170 RGD:6907045
RGD:9686094
G Cwc15 CWC15 spliceosome-associated protein JBrowse link 8 12,994,131 13,004,958 RGD:6907045
RGD:9686094
G Ddx23 DEAD-box helicase 23 JBrowse link 7 140,325,453 140,342,730 RGD:6907045
RGD:9686089
RGD:9686093
G Ddx39b DExD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:9686093
G Ddx42 DEAD-box helicase 42 JBrowse link 10 94,407,094 94,439,052 RGD:6907045
RGD:9686091
G Ddx46 DEAD-box helicase 46 JBrowse link 17 9,475,275 9,519,545 RGD:6907045
RGD:9686093
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:6907045
G Dhx15 DEAH-box helicase 15 JBrowse link 14 61,136,740 61,174,880 RGD:6907045
G Dhx16 DEAH-box helicase 16 JBrowse link 20 3,368,971 3,386,087 RGD:6907045
RGD:9686093
G Dhx38 DEAH-box helicase 38 JBrowse link 19 42,110,291 42,127,540 RGD:6907045
RGD:9686093
G Dhx8 DEAH-box helicase 8 JBrowse link 10 89,645,979 89,683,839 RGD:6907045
RGD:9686093
G Eftud2 elongation factor Tu GTP binding domain containing 2 JBrowse link 10 90,932,071 90,983,971 RGD:6907045
RGD:9686093
RGD:9686090
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:6907045
RGD:9686404
G Hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 RGD:9686091
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:6907045
RGD:9686091
RGD:9686089
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:9686091
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 JBrowse link 3 62,481,222 62,491,356 RGD:6907045
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B JBrowse link 10 34,955,713 34,961,662 RGD:9686091
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:6907045
RGD:9686091
RGD:9686089
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:9686091
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 JBrowse link 10 35,872,619 35,879,911 RGD:9686091
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:6907045
RGD:9686091
RGD:9686089
G Hnrnpl heterogeneous nuclear ribonucleoprotein L JBrowse link 1 86,994,090 87,006,776 RGD:9686091
G Hnrnpm heterogeneous nuclear ribonucleoprotein M JBrowse link 7 18,516,253 18,554,536 RGD:9686089
RGD:9686091
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 5 154,668,194 154,699,967 RGD:9686091
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:6907045
RGD:9686091
RGD:9686089
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6907045
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:6907045
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:6907045
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:6907045
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6907045
RGD:9686094
G Isy1 ISY1 splicing factor homolog JBrowse link 4 119,721,659 119,742,349 RGD:9686094
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 20 4,966,817 4,970,567 RGD:6907045
RGD:9686091
RGD:9686089
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 4 123,162,086 123,168,330 RGD:6907045
RGD:9686091
RGD:9686089
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 16 20,506,399 20,511,818 RGD:6907045
RGD:9686091
RGD:9686089
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 4 87,016,003 87,019,219 RGD:6907045
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 19 32,770,640 32,785,215 RGD:6907045
RGD:9686091
RGD:9686089
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 7 11,724,932 11,732,020 RGD:6907045
RGD:9686091
RGD:9686089
G Lsm8 LSM8 homolog, U6 small nuclear RNA associated JBrowse link 4 45,555,077 45,560,943 RGD:9686089
RGD:9686091
G Magoh mago homolog, exon junction complex subunit JBrowse link 5 127,480,465 127,487,617 RGD:6907045
G Magohb mago homolog B, exon junction complex subunit JBrowse link 4 165,514,584 165,522,366 RGD:6907045
RGD:9686404
G Mbnl1 muscleblind-like splicing regulator 1 JBrowse link 2 150,698,248 150,867,791 RGD:9686382
G Ncbp1 nuclear cap binding protein subunit 1 JBrowse link 5 61,734,118 61,767,098 RGD:6907045
G Pcbp1 poly(rC) binding protein 1 JBrowse link 4 118,327,185 118,329,223 RGD:6907045
G Phf5a PHD finger protein 5A JBrowse link 7 123,095,286 123,101,851 RGD:6907045
G Pigz phosphatidylinositol glycan anchor biosynthesis, class Z JBrowse link 11 72,930,040 72,936,002 RGD:6907045
G Plrg1 pleiotropic regulator 1 JBrowse link 2 182,040,338 182,056,669 RGD:6907045
RGD:9686094
G Pnn pinin, desmosome associated protein JBrowse link 6 80,159,364 80,167,677 RGD:9686404
G Ppie peptidylprolyl isomerase E JBrowse link 5 140,822,141 140,835,244 RGD:6907045
RGD:9686376
RGD:9686094
G Ppig peptidylprolyl isomerase G JBrowse link 3 55,959,756 55,990,040 RGD:9686376
G Ppih peptidylprolyl isomerase H JBrowse link 5 138,343,934 138,361,743 RGD:6907045
RGD:9686376
G Ppil1 peptidylprolyl isomerase like 1 JBrowse link 20 6,515,638 6,864,571 RGD:6907045
RGD:9686376
RGD:9686094
G Ppil2 peptidylprolyl isomerase like 2 JBrowse link 11 88,147,342 88,169,968 RGD:9686376
G Ppil3 peptidylprolyl isomerase like 3 JBrowse link 9 65,315,407 65,329,145 RGD:9686376
G Pqbp1 polyglutamine binding protein 1 JBrowse link X 15,448,570 15,453,130 RGD:6907045
G Prpf18 pre-mRNA processing factor 18 JBrowse link 17 77,601,914 77,632,507 RGD:6907045
RGD:9686092
G Prpf19 pre-mRNA processing factor 19 JBrowse link 1 226,947,065 226,958,147 RGD:6907045
RGD:9686094
G Prpf3 pre-mRNA processing factor 3 JBrowse link 2 197,947,010 197,971,464 RGD:6907045
RGD:9686089
G Prpf31 pre-mRNA processing factor 31 JBrowse link 1 64,150,786 64,162,461 RGD:6907045
RGD:9686089
G Prpf38a pre-mRNA processing factor 38A JBrowse link 5 128,174,835 128,186,532 RGD:6907045
G Prpf38b pre-mRNA processing factor 38B JBrowse link 2 211,706,245 211,715,271 RGD:6907045
G Prpf4 pre-mRNA processing factor 4 JBrowse link 5 78,267,248 78,281,172 RGD:6907045
RGD:9686089
G Prpf40a pre-mRNA processing factor 40 homolog A JBrowse link 3 38,680,583 38,741,570 RGD:6907045
G Prpf6 pre-mRNA processing factor 6 JBrowse link 3 177,098,137 177,162,937 RGD:6907045
RGD:9686089
G Prpf8 pre-mRNA processing factor 8 JBrowse link 10 63,635,239 63,658,360 RGD:6907045
RGD:9686090
G Ptbp1 polypyrimidine tract binding protein 1 JBrowse link 7 12,663,965 12,673,723 RGD:9686381
G Ptbp2 polypyrimidine tract binding protein 2 JBrowse link 2 223,261,444 223,323,075 RGD:9686382
G Puf60 poly-U binding splicing factor 60 JBrowse link 7 117,129,237 117,140,234 RGD:6907045
G Qki QKI, KH domain containing, RNA binding JBrowse link 1 50,983,133 51,061,103 RGD:9686381
G Rbm17 RNA binding motif protein 17 JBrowse link 17 70,586,345 70,603,289 RGD:6907045
G Rbm22 RNA binding motif protein 22 JBrowse link 18 55,828,158 55,839,421 RGD:6907045
RGD:9686094
G Rbm25 RNA binding motif protein 25 JBrowse link 6 107,117,888 107,165,538 RGD:6907045
G Rbm25l1 RNA binding motif protein 25-like 1 JBrowse link 10 10,457,316 10,460,540 RGD:6907045
G Rbm8a RNA binding motif protein 8A JBrowse link 2 198,755,261 198,758,028 RGD:6907045
RGD:9686404
G Rbmx RNA binding motif protein, X-linked JBrowse link X 159,881,835 159,891,405 RGD:6907045
RGD:9686091
RGD:9686089
G Rbmxl1 RBMX like 1 JBrowse link 19 33,081,473 33,084,988 RGD:6907045
G RGD1566078 similar to NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (Sperm specific antigen 1) JBrowse link X 152,781,177 152,781,621 RGD:6907045
G Rnps1 RNA binding protein with serine rich domain 1 JBrowse link 10 13,786,339 13,796,720 RGD:9686404
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP JBrowse link 1 220,762,496 220,771,158 RGD:6907045
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein JBrowse link 12 48,628,198 48,656,096 RGD:9686090
G Sf1 splicing factor 1 JBrowse link 1 221,735,512 221,749,216 RGD:9686089
G Sf3a1 splicing factor 3a, subunit 1 JBrowse link 14 84,393,182 84,413,931 RGD:6907045
RGD:9686091
G Sf3a2 splicing factor 3a, subunit 2 JBrowse link 7 11,777,826 11,784,373 RGD:6907045
RGD:9686091
G Sf3a3 splicing factor 3a, subunit 3 JBrowse link 5 142,702,721 142,722,350 RGD:6907045
RGD:9686091
G Sf3b1 splicing factor 3b, subunit 1 JBrowse link 9 61,594,620 61,634,510 RGD:6907045
RGD:9686091
G Sf3b2 splicing factor 3b, subunit 2 JBrowse link 1 220,645,685 220,665,611 RGD:6907045
RGD:9686091
G Sf3b3 splicing factor 3b, subunit 3 JBrowse link 19 43,392,071 43,429,582 RGD:6907045
RGD:9686091
G Sf3b4 splicing factor 3b, subunit 4 JBrowse link 2 198,312,428 198,317,180 RGD:6907045
RGD:9686091
G Sf3b5 splicing factor 3b, subunit 5 JBrowse link 1 7,101,715 7,102,427 RGD:6907045
RGD:9686091
G Sf3b6 splicing factor 3B, subunit 6 JBrowse link 6 29,991,232 29,999,668 RGD:9686091
G Slu7 SLU7 homolog, splicing factor JBrowse link 10 29,029,556 29,044,919 RGD:6907045
RGD:9686092
G Smndc1 survival motor neuron domain containing 1 JBrowse link 1 274,096,068 274,107,138 RGD:6907045
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 JBrowse link 3 119,640,324 119,669,651 RGD:9686090
RGD:9686093
G Snrnp27 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 JBrowse link 4 118,478,075 118,487,633 RGD:6907045
G Snrnp40 small nuclear ribonucleoprotein U5 subunit 40 JBrowse link 5 148,577,498 148,610,658 RGD:6907045
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 JBrowse link 1 101,367,470 101,388,153 RGD:6907045
RGD:9686090
G Snrpa small nuclear ribonucleoprotein polypeptide A JBrowse link 1 83,999,670 84,008,429 RGD:6907045
RGD:9686090
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' JBrowse link 1 126,961,389 126,974,453 RGD:9686091
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 JBrowse link 3 122,696,125 122,703,734 RGD:6907045
RGD:9686091
RGD:9686089
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 JBrowse link 3 137,138,082 137,147,575 RGD:6907045
RGD:9686091
G Snrpc small nuclear ribonucleoprotein polypeptide C JBrowse link 20 7,409,401 7,427,581 RGD:6907045
RGD:9686090
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide JBrowse link 18 1,866,066 1,876,613 RGD:6907045
RGD:9686091
RGD:9686089
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide JBrowse link 1 80,057,140 80,059,990 RGD:6907045
RGD:9686091
RGD:9686089
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide JBrowse link 20 14,080,562 14,095,644 RGD:9686089
RGD:9686091
G Snrpe small nuclear ribonucleoprotein polypeptide E JBrowse link 13 50,252,707 50,258,951 RGD:6907045
RGD:9686089
RGD:9686091
G Snrpf small nuclear ribonucleoprotein polypeptide F JBrowse link 7 34,478,331 34,485,034 RGD:6907045
RGD:9686091
RGD:9686089
G Snrpg small nuclear ribonucleoprotein polypeptide G JBrowse link 4 118,167,267 118,174,846 RGD:9686089
RGD:9686091
G Snu13 small nuclear ribonucleoprotein 13 JBrowse link 7 123,282,754 123,287,721 RGD:6907045
RGD:9686089
G Snw1 SNW domain containing 1 JBrowse link 6 111,483,698 111,507,782 RGD:6907045
RGD:9686094
G Srrm1 serine and arginine repetitive matrix 1 JBrowse link 5 153,675,619 153,708,187 RGD:9686091
RGD:9686404
G Srrm2 serine/arginine repetitive matrix 2 JBrowse link 10 13,128,820 13,162,956 RGD:9686091
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:9686089
RGD:9686091
G Srsf10 serine and arginine rich splicing factor 10 JBrowse link 5 154,205,358 154,219,550 RGD:9686089
RGD:9686091
G Srsf11 serine and arginine rich splicing factor 11 JBrowse link 2 264,837,463 264,864,296 RGD:9686091
G Srsf12 serine and arginine rich splicing factor 12 JBrowse link 5 48,456,777 48,484,017 RGD:9686091
G Srsf2 serine and arginine rich splicing factor 2 JBrowse link 10 105,792,779 105,795,986 RGD:9686091
G Srsf4 serine and arginine rich splicing factor 4 JBrowse link 5 150,032,999 150,060,769 RGD:9686089
RGD:9686091
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:9686089
RGD:9686091
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:9686089
RGD:9686091
G Srsf7 serine and arginine rich splicing factor 7 JBrowse link 6 2,879,312 2,886,505 RGD:9686089
RGD:9686091
G Srsf9 serine and arginine rich splicing factor 9 JBrowse link 12 47,039,714 47,046,022 RGD:9686089
RGD:9686091
G Syf2 SYF2 pre-mRNA-splicing factor JBrowse link 5 153,269,638 153,277,562 RGD:6907045
RGD:9686094
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein JBrowse link 8 96,100,692 96,266,342 RGD:9686091
G Tcerg1 transcription elongation regulator 1 JBrowse link 18 36,796,290 36,889,966 RGD:6907045
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:6907045
G Thoc2 THO complex 2 JBrowse link X 128,153,824 128,268,327 RGD:6907045
G Thoc3 THO complex 3 JBrowse link 17 10,676,943 10,686,134 RGD:6907045
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 JBrowse link 1 199,844,854 199,865,843 RGD:9686381
G Tra2a transformer 2 alpha homolog JBrowse link 4 78,905,380 78,924,203 RGD:6907045
G Tra2b transformer 2 beta homolog JBrowse link 11 82,373,828 82,392,208 RGD:6907045
G U2af1 U2 small nuclear RNA auxiliary factor 1 JBrowse link 20 10,396,652 10,407,564 RGD:9686089
G U2af2 U2 small nuclear RNA auxiliary factor 2 JBrowse link 1 72,312,260 72,329,828 RGD:6907045
RGD:9686089
G U2surp U2 snRNP-associated SURP domain containing JBrowse link 8 103,242,095 103,299,082 RGD:6907045
G Usp39 ubiquitin specific peptidase 39 JBrowse link 4 100,181,408 100,211,425 RGD:6907045
G Wbp11 WW domain binding protein 11 JBrowse link 4 170,772,166 170,785,613 RGD:6907045
G Xab2 XPA binding protein 2 JBrowse link 12 2,158,391 2,170,397 RGD:6907045
RGD:9686094
G Zmat2 zinc finger, matrin type 2 JBrowse link 18 29,639,991 29,644,626 RGD:6907045

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6015
    regulatory pathway 3818
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1692
        RNA processing pathway 289
          RNA maturation pathway 190
            mRNA maturation pathway 173
              spliceosome pathway 148
Path 2
Term Annotations click to browse term
  pathway 6015
    regulatory pathway 3818
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1692
        transcription pathway 1021
          RNA polymerase transcription pathway 375
            eukaryotic RNA polymerase transcription pathway 375
              RNA polymerase II transcription pathway 308
                lncRNA maturation pathway 148
                  spliceosome pathway 148
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.