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The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:lipoic acid metabolic pathway
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Accession:PW:0001063 term browser browse the term
Definition:The metabolic reactions involving lipoic acid, a compound derived from octanoic acid that contains two sulfur centers. Lipoic acid is a co-factor for the pyruvate dehydrogenase complex responsible for the irreversible decarboxylation of pyruvate to acetyl-CoA.
Synonyms:related_synonym: lipoate metabolic process

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lipoic acid metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lias lipoic acid synthetase IEA KEGG rno:00785 NCBI chr14:42,876,699...42,893,824
Ensembl chr14:42,876,699...42,893,783
JBrowse link
G Lipt1 lipoyltransferase 1 IEA KEGG rno:00785 NCBI chr 9:40,107,938...40,118,268
Ensembl chr 9:40,098,615...40,113,565
JBrowse link
G Lipt2 lipoyl(octanoyl) transferase 2 IEA KEGG rno:00785 NCBI chr 1:154,504,563...154,506,890
Ensembl chr 1:154,504,563...154,506,890
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6097
    classic metabolic pathway 1854
      metabolic pathway of cofactors, vitamins, nutrients 367
        lipoic acid metabolic pathway 3
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