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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:rheumatoid arthritis pathway
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Accession:PW:0001019 term browser browse the term
Definition:Rheumatoid arthritis is an autoimmune condition characterized by persistent inflammation. Several pro-inflammatory cytokines and chemokines are over-activated.
Synonyms:exact_synonym: atrophic arthritis pathway;   rheumatic arthritis pathway;   rheumatic polyarthritis pathway;   rheumatoid arthritis disease pathway
 related_synonym: KEGG:05323


show annotations for term's descendants           Sort by:
rheumatoid arthritis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant IEA KEGG rno:05323 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929 		JBrowse link
G Angpt1 angiopoietin 1 IEA KEGG rno:05323 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 IEA KEGG rno:05323 NCBI chr  X:157,231,243...157,238,323
Ensembl chr  X:157,225,327...157,238,323 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 IEA KEGG rno:05323 NCBI chr10:86,436,089...86,490,185
Ensembl chr10:86,436,141...86,490,181 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 IEA KEGG rno:05323 NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 IEA KEGG rno:05323 NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B IEA KEGG rno:05323 NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C IEA KEGG rno:05323 NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 IEA KEGG rno:05323 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 IEA KEGG rno:05323 NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 IEA KEGG rno:05323 NCBI chr10:16,984,084...17,007,156
Ensembl chr10:16,984,084...17,028,858 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 IEA KEGG rno:05323 NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A IEA KEGG rno:05323 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 IEA KEGG rno:05323 NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:117,781,444...117,800,103 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 IEA KEGG rno:05323 NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 IEA KEGG rno:05323 NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:71,719,404...71,757,184 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 IEA KEGG rno:05323 NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D IEA KEGG rno:05323 NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 IEA KEGG rno:05323 NCBI chr 4:155,694,534...155,716,660
Ensembl chr 4:155,694,534...155,716,678 		JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 IEA KEGG rno:05323 NCBI chr 6:13,417,046...13,425,628
Ensembl chr 6:13,404,848...13,456,037 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F IEA KEGG rno:05323 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 IEA KEGG rno:05323 NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 IEA KEGG rno:05323 NCBI chr20:3,592,374...3,595,986
Ensembl chr20:3,592,364...3,595,475 		JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 IEA KEGG rno:05323 NCBI chr13:52,351,787...52,376,784
Ensembl chr13:52,351,801...52,375,594 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H IEA KEGG rno:05323 NCBI chr 5:19,176,849...19,282,516
Ensembl chr 5:19,176,849...19,282,516 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 IEA KEGG rno:05323 NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEA KEGG rno:05323 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 IEA KEGG rno:05323 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEA KEGG rno:05323 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Cd28 Cd28 molecule IEA KEGG rno:05323 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Cd80 Cd80 molecule IEA KEGG rno:05323 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd86 CD86 molecule IEA KEGG rno:05323 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Csf1 colony stimulating factor 1 IEA KEGG rno:05323 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468 		JBrowse link
G Csf2 colony stimulating factor 2 IEA KEGG rno:05323 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA KEGG rno:05323 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973 		JBrowse link
G Ctsk cathepsin K IEA KEGG rno:05323 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Ctsl cathepsin L IEA KEGG rno:05323 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEA KEGG rno:05323 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEA KEGG rno:05323 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:05323 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEA KEGG rno:05323 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifng interferon gamma IEA KEGG rno:05323 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il11 interleukin 11 IEA KEGG rno:05323 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915 		JBrowse link
G Il15 interleukin 15 IEA KEGG rno:05323 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il18 interleukin 18 IEA KEGG rno:05323 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:05323 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:05323 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il23a interleukin 23 subunit alpha IEA KEGG rno:05323 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il6 interleukin 6 IEA KEGG rno:05323 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgal integrin subunit alpha L IEA KEGG rno:05323 NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225 		JBrowse link
G Itgb2 integrin subunit beta 2 IEA KEGG rno:05323 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:05323 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Ltb lymphotoxin beta IEA KEGG rno:05323 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054 		JBrowse link
G Mmp1 matrix metallopeptidase 1 IEA KEGG rno:05323 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEA KEGG rno:05323 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Pgf placental growth factor IEA KEGG rno:05323 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G RT1-Ba RT1 class II, locus Ba IEA KEGG rno:05323 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-Bb RT1 class II, locus Bb IEA KEGG rno:05323 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118 		JBrowse link
G RT1-Da RT1 class II, locus Da IEA KEGG rno:05323 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 IEA KEGG rno:05323 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G RT1-DMa RT1 class II, locus DMa IEA KEGG rno:05323 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335 		JBrowse link
G RT1-DMb RT1 class II, locus DMb IEA KEGG rno:05323 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246 		JBrowse link
G RT1-DOa RT1 class II, locus DOa IEA KEGG rno:05323 NCBI chr20:4,755,287...4,758,491
Ensembl chr20:4,755,499...4,758,478 		JBrowse link
G RT1-DOb RT1 class II, locus DOb IEA KEGG rno:05323 NCBI chr20:4,621,336...4,627,537
Ensembl chr20:4,619,694...4,627,523 		JBrowse link
G RT1-Ha RT1 class II, locus Ha IEA KEGG rno:05323 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 IEA KEGG rno:05323 NCBI chr 1:210,556,270...210,568,021
Ensembl chr 1:210,556,270...210,568,033 		JBrowse link
G Tek TEK receptor tyrosine kinase IEA KEGG rno:05323 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:05323 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:05323 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:05323 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Tlr2 toll-like receptor 2 IEA KEGG rno:05323 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 IEA KEGG rno:05323 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:05323 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A IEA KEGG rno:05323 NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257 		JBrowse link
G Tnfsf11 TNF superfamily member 11 IEA KEGG rno:05323 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf13 TNF superfamily member 13 IEA KEGG rno:05323 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815 		JBrowse link
G Tnfsf13b TNF superfamily member 13b IEA KEGG rno:05323 NCBI chr16:86,164,377...86,195,072
Ensembl chr16:86,164,377...86,194,499 		JBrowse link
G Vegfa vascular endothelial growth factor A IEA KEGG rno:05323 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfb vascular endothelial growth factor B IEA KEGG rno:05323 NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:213,600,966...213,607,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    disease pathway 1954
      musculoskeletal disease pathway 171
        arthritis pathway 116
          rheumatoid arthritis pathway 79
paths to the root