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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:adenosine signaling pathway
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Accession:PW:0000998 term browser browse the term
Definition:Adenosine signaling is involved in the regulation of several physiological processes. It uses four receptors of the GPCR family that activate the Gaphas or Galphai types of G proteins to increase or decrease the levels of cAMP. The adenosine receptors are a class of purinergic or purinoreceptors.
Synonyms:related_synonym: SMP:00320;   SMP:00321


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adenosine signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00320 SMP:00321 NCBI chr34:6,139,931...6,527,677
Ensembl chr34:6,140,276...6,527,677 		JBrowse link
G ADORA2A adenosine A2a receptor ISO SMPDB SMP:00320 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598 		JBrowse link
G ADORA2B adenosine A2b receptor ISO SMPDB SMP:00321 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 ISO SMPDB SMP:00320 SMP:00321 NCBI chr22:59,207,278...59,305,240
Ensembl chr22:59,206,868...59,303,049 		JBrowse link
G ATF2 activating transcription factor 2 ISO SMPDB SMP:00320 SMP:00321 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO SMPDB SMP:00320 SMP:00321 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO SMPDB SMP:00320 SMP:00321 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO SMPDB SMP:00320 SMP:00321 NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G ELK1 ETS transcription factor ELK1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr  X:41,256,205...41,270,656
Ensembl chr  X:41,257,482...41,270,776 		JBrowse link
G GNAS GNAS complex locus ISO SMPDB SMP:00320 SMP:00321 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657 		JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295 		JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 6:77,316,649...77,378,356
Ensembl chr 6:77,338,685...77,374,937 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO SMPDB SMP:00320 SMP:00321 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO SMPDB SMP:00320 SMP:00321 NCBI chr16:23,359,551...23,419,114
Ensembl chr16:23,359,813...23,419,075 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO SMPDB SMP:00320 SMP:00321 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G LOC403934 cell division cycle 42 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO SMPDB SMP:00320 SMP:00321 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 9:15,840,714...15,962,400
Ensembl chr 9:15,840,983...15,952,026 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO SMPDB SMP:00320 SMP:00321 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209 		JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 1:49,590,615...49,702,289
Ensembl chr 1:49,548,274...49,702,289 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 ISO SMPDB SMP:00320 SMP:00321 NCBI chr10:16,977,133...16,984,764 JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO SMPDB SMP:00320 SMP:00321 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 ISO SMPDB SMP:00320 SMP:00321 NCBI chr28:14,902,212...14,910,437
Ensembl chr28:14,902,706...14,910,395 		JBrowse link
G NFKBIA NFKB inhibitor alpha ISO SMPDB SMP:00320 SMP:00321 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PARD6A par-6 family cell polarity regulator alpha ISO SMPDB SMP:00320 SMP:00321 NCBI chr 5:81,787,424...81,789,833
Ensembl chr 5:81,787,553...81,790,324 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO SMPDB SMP:00320 SMP:00321 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00320 SMP:00321 NCBI chr 6:63,615,445...63,729,386
Ensembl chr 6:63,618,323...63,730,146 		JBrowse link
G PRKCZ protein kinase C zeta ISO SMPDB SMP:00320 SMP:00321 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO SMPDB SMP:00320 SMP:00321 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 ISO SMPDB SMP:00320 SMP:00321 NCBI chr15:56,133,094...56,353,609
Ensembl chr15:56,174,578...56,352,569 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO SMPDB SMP:00320 SMP:00321 NCBI chr27:6,993,452...7,030,372
Ensembl chr27:6,993,452...7,017,316 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 ISO SMPDB SMP:00320 SMP:00321 NCBI chr 2:73,497,128...73,533,853
Ensembl chr 2:73,497,473...73,534,378 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    signaling pathway 1939
      nucleoside and nucleotide mediated signaling pathway 39
        adenosine signaling pathway 39
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