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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:interleukin-23 signaling pathway
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Accession:PW:0000915 term browser browse the term
Definition:Interleukin-23, an interleukin-12 family member, is a heterodimeric, inflammatory cytokine important in T helper cell effector cytokine secretion and proliferation; it also stimulates angiogenesis.
Synonyms:exact_synonym: Il-23 signaling pathway
 related_synonym: Interleukin-23 signaling;   interleukin-23-mediated signaling pathway


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interleukin-23 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO PID PID:200154 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO PID PID:200154 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex ISO PID PID:200154 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD4 CD4 molecule ISO PID PID:200154 NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771 		JBrowse link
G IFNG interferon gamma ISO PID PID:200154 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IL12B interleukin 12B ISO PID PID:200154 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 ISO PID PID:200154 NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538 		JBrowse link
G IL17A interleukin 17A ISO PID PID:200154 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IL17F interleukin 17F ISO PID PID:200154 NCBI chr12:19,904,283...19,908,497
Ensembl chr12:19,904,126...19,908,619 		JBrowse link
G IL18 interleukin 18 ISO PID PID:200154 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO PID PID:200154 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein ISO PID PID:200154 NCBI chr10:40,578,503...40,605,800
Ensembl chr10:40,581,096...40,605,766 		JBrowse link
G IL19 interleukin 19 ISO PID PID:200154 NCBI chr 7:6,000,994...6,006,959
Ensembl chr 7:6,000,907...6,006,870 		JBrowse link
G IL1B interleukin 1 beta ISO PID PID:200154 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL2 interleukin 2 ISO PID PID:200154 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO PID PID:200154 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359 		JBrowse link
G IL23R interleukin 23 receptor ISO PID PID:200154 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474 		JBrowse link
G IL24 interleukin 24 ISO PID PID:200154 NCBI chr 7:6,043,249...6,047,097
Ensembl chr 7:6,041,625...6,047,097 		JBrowse link
G IL6 interleukin 6 ISO PID PID:200154 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G ITGA3 integrin subunit alpha 3 ISO PID PID:200154 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422 		JBrowse link
G JAK2 Janus kinase 2 ISO PID PID:200154 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G MPO myeloperoxidase ISO PID PID:200154 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO PID PID:200154 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G NFKBIA NFKB inhibitor alpha ISO PID PID:200154 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO PID PID:200154 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200154 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200154 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO PID PID:200154 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO PID PID:200154 NCBI chr 9:2,859,267...2,859,944 JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200154 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO PID PID:200154 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO PID PID:200154 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISO PID PID:200154 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G TNF tumor necrosis factor ISO PID PID:200154 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TYK2 tyrosine kinase 2 ISO PID PID:200154 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    signaling pathway 1939
      signaling pathway pertinent to immunity 418
        cytokine mediated signaling pathway 334
          Interleukin mediated signaling pathway 247
            interleukin-12 family mediated signaling pathway 86
              interleukin-23 signaling pathway 35
paths to the root