PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: interleukin-4 signaling pathway
Accession: PW:0000912
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Definition: Interleukin-4 is a member of the interleukin 2 family of cytokines whose signaling is important for the differentiation of naive T helper cells.
Synonyms: exact_synonym: Il-4 signaling pathway
related_synonym: interleukin-4-mediated signaling pathway
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Akt1
AKT serine/threonine kinase 1
ISO
PID
PID:200022
NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
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Alox15
arachidonate 15-lipoxygenase
ISO
PID
PID:200022
NCBI chrNW_004955467:10,032,792...10,039,789
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Arg1
arginase 1
ISO
PID
PID:200022
NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972
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Bcl6
BCL6 transcription repressor
ISO
PID
PID:200022
NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259
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Cbl
Cbl proto-oncogene
ISO
PID
PID:200022
NCBI chrNW_004955412:20,307,011...20,388,539
Ensembl chrNW_004955412:20,307,011...20,388,539
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Ccl17
C-C motif chemokine ligand 17
ISO
PID
PID:200022
NCBI chrNW_004955433:15,052,616...15,054,732
Ensembl chrNW_004955433:15,053,061...15,054,572
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Ccl26
C-C motif chemokine ligand 26
ISO
PID
PID:200022
NCBI chrNW_004955456:14,554,583...14,558,967
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Cd40lg
CD40 ligand
ISO
PID
PID:200022
NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
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Cebpb
CCAAT enhancer binding protein beta
ISO
PID
PID:200022
NCBI chrNW_004955445:8,060,432...8,061,289
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Col1a1
collagen type I alpha 1 chain
ISO
PID
PID:200022
NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
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Col1a2
collagen type I alpha 2 chain
ISO
PID
PID:200022
NCBI chrNW_004955432:11,127,961...11,164,145
Ensembl chrNW_004955432:11,128,112...11,163,302
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Dok2
docking protein 2
ISO
PID
PID:200022
NCBI chrNW_004955403:45,410,689...45,421,366
Ensembl chrNW_004955403:45,410,279...45,415,067
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Egr2
early growth response 2
ISO
PID
PID:200022
NCBI chrNW_004955425:16,055,748...16,068,429
Ensembl chrNW_004955425:16,055,748...16,060,048
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Ets1
ETS proto-oncogene 1, transcription factor
ISO
PID
PID:200022
NCBI chrNW_004955412:29,433,730...29,602,389
Ensembl chrNW_004955412:29,432,482...29,545,580
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Fcer2
Fc fragment of IgE receptor II
ISO
PID
PID:200022
NCBI chrNW_004955563:1,587,471...1,596,707
Ensembl chrNW_004955563:1,587,396...1,596,063
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Fes
FES proto-oncogene, tyrosine kinase
ISO
PID
PID:200022
NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005
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Grb2
growth factor receptor bound protein 2
ISO
PID
PID:200022
NCBI chrNW_004955553:2,186,590...2,258,964
Ensembl chrNW_004955553:2,186,590...2,259,456
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Gtf3a
general transcription factor IIIA
ISO
PID
PID:200022
NCBI chrNW_004955497:6,836,568...6,852,177
Ensembl chrNW_004955497:6,842,960...6,851,835
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Hmga1
high mobility group AT-hook 1
ISO
PID
PID:200022
NCBI chrNW_004955437:2,478,414...2,486,809
Ensembl chrNW_004955437:2,478,414...2,486,809
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Il10
interleukin 10
ISO
PID
PID:200022
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
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Il13ra1
interleukin 13 receptor subunit alpha 1
ISO
PID
PID:200022
NCBI chrNW_004955534:1,157,758...1,205,158
Ensembl chrNW_004955534:1,160,340...1,204,911
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Il13ra2
interleukin 13 receptor subunit alpha 2
ISO
PID
PID:200022
NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272
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Il2rg
interleukin 2 receptor subunit gamma
ISO
PID
PID:200022
NCBI chrNW_004955475:10,676,592...10,680,565
Ensembl chrNW_004955475:10,676,870...10,680,517
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Il4
interleukin 4
ISO
PID
PID:200022
NCBI chrNW_004955408:4,058,052...4,065,999
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Il4r
interleukin 4 receptor
ISO
PID
PID:200022
NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
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Il5
interleukin 5
ISO
PID
PID:200022
NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
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Inpp5d
inositol polyphosphate-5-phosphatase D
ISO
PID
PID:200022
NCBI chrNW_004955453:2,938,659...3,037,211
Ensembl chrNW_004955453:2,938,659...3,037,211
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Irf4
interferon regulatory factor 4
ISO
PID
PID:200022
NCBI chrNW_004955465:12,497,534...12,512,529
Ensembl chrNW_004955465:12,497,462...12,513,106
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Irs1
insulin receptor substrate 1
ISO
PID
PID:200022
NCBI chrNW_004955453:7,685,715...7,742,262
Ensembl chrNW_004955453:7,685,715...7,742,262
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Irs2
insulin receptor substrate 2
ISO
PID
PID:200022
NCBI chrNW_004955404:2,531,484...2,555,383
Ensembl chrNW_004955404:2,531,484...2,555,689
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Itgb3
integrin subunit beta 3
ISO
PID
PID:200022
NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746
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Jak1
Janus kinase 1
ISO
PID
PID:200022
NCBI chrNW_004955423:25,501,989...25,581,826
Ensembl chrNW_004955423:25,524,075...25,580,604
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Jak2
Janus kinase 2
ISO
PID
PID:200022
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
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Jak3
Janus kinase 3
ISO
PID
PID:200022
NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643
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Lta
lymphotoxin alpha
ISO
PID
PID:200022
NCBI chrNW_004955437:114,216...116,003
Ensembl chrNW_004955437:114,640...115,529
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Mapk14
mitogen-activated protein kinase 14
ISO
PID
PID:200022
NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083
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Mtor
mechanistic target of rapamycin kinase
ISO
PID
PID:200022
NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
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Myb
MYB proto-oncogene, transcription factor
ISO
PID
PID:200022
NCBI chrNW_004955439:1,523,516...1,560,185
Ensembl chrNW_004955439:1,521,292...1,560,220
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Mybl1
MYB proto-oncogene like 1
ISO
PID
PID:200022
NCBI chrNW_004955444:12,589,464...12,620,602
Ensembl chrNW_004955444:12,589,464...12,620,663
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Oprm1
opioid receptor mu 1
ISO
PID
PID:200022
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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Parp14
poly(ADP-ribose) polymerase family member 14
ISO
PID
PID:200022
NCBI chrNW_004955427:21,878,980...21,929,097
Ensembl chrNW_004955427:21,879,740...21,927,883
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Pigr
polymeric immunoglobulin receptor
ISO
PID
PID:200022
NCBI chrNW_004955406:42,456,450...42,474,489
Ensembl chrNW_004955406:42,453,080...42,474,694
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Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
ISO
PID
PID:200022
NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
ISO
PID
PID:200022
NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820
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Ptpn6
protein tyrosine phosphatase non-receptor type 6
ISO
PID
PID:200022
NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177
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Rps6kb1
ribosomal protein S6 kinase B1
ISO
PID
PID:200022
NCBI chrNW_004955451:3,181,085...3,225,610
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Selp
selectin P
ISO
PID
PID:200022
NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
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Shc1
SHC adaptor protein 1
ISO
PID
PID:200022
NCBI chrNW_004955545:1,468,391...1,479,209
Ensembl chrNW_004955545:1,468,391...1,476,814
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Socs1
suppressor of cytokine signaling 1
ISO
PID
PID:200022
NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109
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Socs3
suppressor of cytokine signaling 3
ISO
PID
PID:200022
NCBI chrNW_004955506:4,222,455...4,225,563
Ensembl chrNW_004955506:4,222,455...4,225,563
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Socs5
suppressor of cytokine signaling 5
ISO
PID
PID:200022
NCBI chrNW_004955441:13,593,342...13,657,389
Ensembl chrNW_004955441:13,593,342...13,657,389
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Sp1
Sp1 transcription factor
ISO
PID
PID:200022
NCBI chrNW_004955458:644,435...677,360
Ensembl chrNW_004955458:644,378...677,441
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Spi1
Spi-1 proto-oncogene
ISO
PID
PID:200022
NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560
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Stat5a
signal transducer and activator of transcription 5A
ISO
PID
PID:200022
NCBI chrNW_004955451:16,305,363...16,319,219
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Stat5b
signal transducer and activator of transcription 5B
ISO
PID
PID:200022
NCBI chrNW_004955451:16,253,645...16,295,337
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Stat6
signal transducer and activator of transcription 6
ISO
PID
PID:200022
NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273
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Tff3
trefoil factor 3
ISO
PID
PID:200022
NCBI chrNW_004955407:39,398,534...39,401,085
Ensembl chrNW_004955407:39,398,074...39,401,248
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Thy1
Thy-1 cell surface antigen
ISO
PID
PID:200022
NCBI chrNW_004955412:20,480,284...20,484,958
Ensembl chrNW_004955412:20,480,284...20,484,958
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