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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:Toll-like receptor signaling pathway
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Accession:PW:0000814 term browser browse the term
Definition:Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators.
Synonyms:related_synonym: TLR signaling pathway;   Toll-Like Receptors Cascades
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show annotations for term's descendants           Sort by:
Toll-like receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 IEA KEGG mmu:04620 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 IEA KEGG mmu:04620 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Akt3 thymoma viral proto-oncogene 3 IEA KEGG mmu:04620 NCBI chr 1:176,847,642...177,091,688
Ensembl chr 1:176,847,639...177,085,769 		JBrowse link
G Casp8 caspase 8 IEA KEGG mmu:04620 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 IEA KEGG mmu:04620 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IEA KEGG mmu:04620 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEA KEGG mmu:04620 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cd14 CD14 antigen IEA
ISO		 KEGG
RGD		 PMID:22119168 mmu:04620, RGD:7247704 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen IEA KEGG mmu:04620 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd80 CD80 antigen IEA KEGG mmu:04620 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697 		JBrowse link
G Cd86 CD86 antigen IEA KEGG mmu:04620 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IEA KEGG mmu:04620 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919 		JBrowse link
G Ctsk cathepsin K IEA KEGG mmu:04620 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEA KEGG mmu:04620 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 IEA KEGG mmu:04620 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 IEA KEGG mmu:04620 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Fadd Fas associated via death domain IEA KEGG mmu:04620 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Fos FBJ osteosarcoma oncogene IEA KEGG mmu:04620 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Ifna1 interferon alpha 1 IEA KEGG mmu:04620 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Ifna11 interferon alpha 11 IEA KEGG mmu:04620 NCBI chr 4:88,738,156...88,738,802
Ensembl chr 4:88,738,196...88,738,768 		JBrowse link
G Ifna12 interferon alpha 12 IEA KEGG mmu:04620 NCBI chr 4:88,520,817...88,521,613
Ensembl chr 4:88,520,817...88,521,613 		JBrowse link
G Ifna13 interferon alpha 13 IEA KEGG mmu:04620 NCBI chr 4:88,561,878...88,562,696
Ensembl chr 4:88,561,878...88,562,696 		JBrowse link
G Ifna14 interferon alpha 14 IEA KEGG mmu:04620 NCBI chr 4:88,489,466...88,490,035
Ensembl chr 4:88,489,466...88,490,035 		JBrowse link
G Ifna15 interferon alpha 15 IEA KEGG mmu:04620 NCBI chr 4:88,475,910...88,476,482
Ensembl chr 4:88,475,910...88,476,482 		JBrowse link
G Ifna2 interferon alpha 2 IEA KEGG mmu:04620 NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149 		JBrowse link
G Ifna4 interferon alpha 4 IEA KEGG mmu:04620 NCBI chr 4:88,760,032...88,761,009
Ensembl chr 4:88,760,098...88,760,658 		JBrowse link
G Ifna5 interferon alpha 5 IEA KEGG mmu:04620 NCBI chr 4:88,753,762...88,754,331
Ensembl chr 4:88,753,762...88,754,331 		JBrowse link
G Ifna6 interferon alpha 6 IEA KEGG mmu:04620 NCBI chr 4:88,745,627...88,746,269
Ensembl chr 4:88,745,653...88,746,222 		JBrowse link
G Ifna7 interferon alpha 7 IEA KEGG mmu:04620 NCBI chr 4:88,734,462...88,735,037
Ensembl chr 4:88,734,465...88,735,037 		JBrowse link
G Ifna9 interferon alpha 9 IEA KEGG mmu:04620 NCBI chr 4:88,510,050...88,510,622
Ensembl chr 4:88,510,050...88,510,622 		JBrowse link
G Ifnab interferon alpha B IEA KEGG mmu:04620 NCBI chr 4:88,608,836...88,609,505
Ensembl chr 4:88,608,539...88,609,596 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IEA KEGG mmu:04620 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Ifnar2 interferon (alpha and beta) receptor 2 IEA KEGG mmu:04620 NCBI chr16:91,166,517...91,202,477
Ensembl chr16:91,169,671...91,202,477 		JBrowse link
G Ifnb1 interferon beta 1, fibroblast IEA KEGG mmu:04620 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IEA KEGG mmu:04620 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon IEA KEGG mmu:04620 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma IEA KEGG mmu:04620 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Il12a interleukin 12a IEA KEGG mmu:04620 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Il12b interleukin 12b IEA KEGG mmu:04620 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il1b interleukin 1 beta IEA KEGG mmu:04620 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 IEA KEGG mmu:04620 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 ISO RGD PMID:21235323 RGD:5685014 NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 IMP RGD PMID:28954388 RGD:34888230 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696 		JBrowse link
G Irf3 interferon regulatory factor 3 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272 		JBrowse link
G Irf5 interferon regulatory factor 5 IEA KEGG mmu:04620 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Irf7 interferon regulatory factor 7 IEA KEGG mmu:04620 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394 		JBrowse link
G Jun jun proto-oncogene IEA KEGG mmu:04620 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Lbp lipopolysaccharide binding protein IEA
ISO		 KEGG
RGD		 PMID:22119168 mmu:04620, RGD:7247704 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Ly96 lymphocyte antigen 96 ISO
IEA		 KEGG
RGD		 PMID:21741580 PMID:22119168 mmu:04620, RGD:5685019, RGD:7247704 NCBI chr 1:16,758,680...16,779,829
Ensembl chr 1:16,758,275...16,779,835 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 IEA KEGG mmu:04620 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 IEA KEGG mmu:04620 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 IEA KEGG mmu:04620 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 IEA KEGG mmu:04620 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEA KEGG mmu:04620 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 IEA KEGG mmu:04620 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 IEA KEGG mmu:04620 NCBI chr18:4,331,325...4,352,978
Ensembl chr18:4,331,327...4,353,015 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 IEA KEGG mmu:04620 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk10 mitogen-activated protein kinase 10 IEA KEGG mmu:04620 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA KEGG mmu:04620 NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG mmu:04620 NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906 		JBrowse link
G Mapk13 mitogen-activated protein kinase 13 IEA KEGG mmu:04620 NCBI chr17:28,988,260...28,997,678
Ensembl chr17:28,988,271...28,999,207 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IEA KEGG mmu:04620 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 IEA KEGG mmu:04620 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA KEGG mmu:04620 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG mmu:04620 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA KEGG mmu:04620 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IEA KEGG mmu:04620 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IEA KEGG mmu:04620 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IEA KEGG mmu:04620 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA KEGG mmu:04620 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IEA KEGG mmu:04620 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG mmu:04620 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG mmu:04620 NCBI chr 8:71,220,820...71,229,356
Ensembl chr 8:71,220,820...71,229,357 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG mmu:04620 NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253
Ensembl chr 4:116,078,815...116,160,253 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 IEA KEGG mmu:04620 NCBI chr11:68,322,951...68,388,675
Ensembl chr11:68,322,947...68,388,675 		JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG mmu:04620 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) IEA KEGG mmu:04620 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130 		JBrowse link
G Spp1 secreted phosphoprotein 1 IEA KEGG mmu:04620 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA KEGG mmu:04620 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO
IEA		 KEGG
RGD		 PMID:20940366 mmu:04620, RGD:5685016 NCBI chr15:80,017,333...80,045,908
Ensembl chr15:80,017,328...80,045,908 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO
IEA		 KEGG
RGD		 PMID:20940366 mmu:04620, RGD:5685016 NCBI chr10:7,781,412...7,832,039
Ensembl chr10:7,781,417...7,831,994 		JBrowse link
G Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 ISO RGD PMID:20940366 RGD:5685016 NCBI chr  X:84,617,466...84,678,075
Ensembl chr  X:84,617,628...84,678,075 		JBrowse link
G Tbk1 TANK-binding kinase 1 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr18:46,691,298...46,707,600
Ensembl chr18:46,690,358...46,707,600 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr1 toll-like receptor 1 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:21235323 mmu:04620, RGD:1643119, RGD:5685014 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906 		JBrowse link
G Tlr2 toll-like receptor 2 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:18353287 PMID:21235323 mmu:04620, RGD:1643119, RGD:5684896, RGD:5685014 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr3 toll-like receptor 3 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:21235323 mmu:04620, RGD:1643119, RGD:5685014 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117 		JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:21235323 PMID:22119168 mmu:04620, RGD:1643119, RGD:5685014, RGD:7247704 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr5 toll-like receptor 5 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:21235323 mmu:04620, RGD:1643119, RGD:5685014 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
G Tlr6 toll-like receptor 6 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:18353287 PMID:21235323 mmu:04620, RGD:1643119, RGD:5684896, RGD:5685014 NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440 		JBrowse link
G Tlr7 toll-like receptor 7 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tlr8 toll-like receptor 8 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr  X:166,024,119...166,047,325
Ensembl chr  X:166,025,692...166,047,325 		JBrowse link
G Tlr9 toll-like receptor 9 ISO
IEA		 KEGG
RGD		 PMID:16973131 PMID:21235323 mmu:04620, RGD:1643119, RGD:5685014 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnf tumor necrosis factor IEA KEGG mmu:04620 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tollip toll interacting protein IEA KEGG mmu:04620 NCBI chr 7:141,435,317...141,456,198
Ensembl chr 7:141,428,550...141,472,244 		JBrowse link
G Tradd TNFRSF1A-associated via death domain ISO RGD PMID:21235323 RGD:5685014 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241 		JBrowse link
G Traf3 TNF receptor-associated factor 3 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr12:111,132,799...111,233,589
Ensembl chr12:111,132,804...111,233,587 		JBrowse link
G Traf6 TNF receptor-associated factor 6 ISO
IEA		 KEGG
RGD		 PMID:21235323 mmu:04620, RGD:5685014 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N ISO RGD PMID:21235323 RGD:5685014 NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519 		JBrowse link
G Ube2v1 ubiquitin-conjugating enzyme E2 variant 1 ISO RGD PMID:21235323 RGD:5685014 NCBI chr 2:167,449,559...167,473,933
Ensembl chr 2:167,449,558...167,474,015 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator ISO RGD PMID:21235323 RGD:5685014 NCBI chr19:3,985,222...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6072
    signaling pathway 2512
      signaling pathway pertinent to immunity 602
        signaling pathway in the innate immune response 167
          pattern recognition receptor mediated signaling pathway 166
            Toll-like receptor signaling pathway 108
              Toll-like receptor 1 signaling pathway 0
              Toll-like receptor 10 signaling pathway 0
              Toll-like receptor 2 signaling pathway 0
              Toll-like receptor 3 signaling pathway 0
              Toll-like receptor 4 signaling pathway 0
              Toll-like receptor 5 signaling pathway 0
              Toll-like receptor 6 signaling pathway 0
              Toll-like receptor 7 signaling pathway 0
              Toll-like receptor 8 signaling pathway 0
              Toll-like receptor 9 signaling pathway 0
              Toll-like receptor TLR1:TLR2 signaling pathway 0
              Toll-like receptor TLR6:TLR2 signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 6072
    regulatory pathway 3689
      immune response pathway 494
        innate immune response pathway 322
          inflammatory response pathway 248
            pattern recognition receptor mediated signaling pathway 166
              Toll-like receptor signaling pathway 108
                Toll-like receptor 1 signaling pathway 0
                Toll-like receptor 10 signaling pathway 0
                Toll-like receptor 2 signaling pathway 0
                Toll-like receptor 3 signaling pathway 0
                Toll-like receptor 4 signaling pathway 0
                Toll-like receptor 5 signaling pathway 0
                Toll-like receptor 6 signaling pathway 0
                Toll-like receptor 7 signaling pathway 0
                Toll-like receptor 8 signaling pathway 0
                Toll-like receptor 9 signaling pathway 0
                Toll-like receptor TLR1:TLR2 signaling pathway 0
                Toll-like receptor TLR6:TLR2 signaling pathway 0
paths to the root