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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:epinephrine signaling pathway via adrenergic receptor beta
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Accession:PW:0000794 term browser browse the term
Definition:Epinephrine acts as a hormone and a neurotransmitter. It promotes various actions by signaling via various adrenergic receptors, G-protein coupled receptor type. The beta receptors couple to the Galphas subunit. Beta 2 receptor may also couple to Galphai.

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epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,330...124,401,739
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:18268361 PMID:19229505 RGD:4140419 RGD:5135529 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,516,947...9,597,976
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:18268361 PMID:19229505 RGD:4140419 RGD:5135529 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,778...52,170,342
JBrowse link
G GNAS GNAS complex locus ISO RGD PMID:19110970 RGD:4140391 NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391 RGD:5135529 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,439...5,227,758
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391 RGD:5135529 NCBI chr14:129,113,933...129,351,135
Ensembl chr14:129,113,603...129,347,152
JBrowse link
G SNX13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chr 9:86,964,038...87,087,200
Ensembl chr 9:86,964,045...87,086,577
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    signaling pathway 1931
      chemical compound signaling pathway 85
        epinephrine signaling pathway 8
          epinephrine signaling pathway via adrenergic receptor beta 8
Path 2
Term Annotations click to browse term
  pathway 4047
    signaling pathway 1931
      signaling pathway pertinent to the brain and nervous system 230
        neuron-to-neuron signaling pathways 130
          neuron-to-neuron signaling pathway via the chemical synapse 128
            epinephrine signaling pathway 8
              epinephrine signaling pathway via adrenergic receptor beta 8
paths to the root