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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:altered androgen signaling pathway
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Accession:PW:0000784 term browser browse the term
Definition:An androgen signaling pathway that deviates from what its normal course should be. Altered androgen signaling, due to upregulation of the androgen receptor, has been implicated in prostate cancer.
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altered androgen signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO RGD PMID:18008377 PMID:23759327 RGD:2326139, RGD:8693397 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ISO RGD PMID:23759327 RGD:8693397 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO RGD PMID:23759327 RGD:8693397 NCBI chr12:37,127,736...37,289,612
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      transcription factor mediated signaling pathway 445
        altered transcription factor mediated signaling pathway 17
          altered androgen signaling pathway 3
Path 2
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      hormone signaling pathway 624
        lipid hormone signaling pathway 224
          steroid hormone signaling pathway 92
            sex steroids signaling pathway 34
              androgen signaling pathway 17
                altered androgen signaling pathway 3
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