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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:aldosterone biosynthetic pathway
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Accession:PW:0000773 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of aldosterone, a C21 mineralocorticoid produced in the outer zone, the zona glomerulosa, of the adrenal cortex from cholesterol as the precursor. It plays important roles in the regulation of water and salt balance.
Synonyms:related_synonym: aldosterone biosynthetic process
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aldosterone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:17926129 RGD:4892309 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP21A1 cytochrome P450 family 21 subfamily A member 1 ISO RGD PMID:15583024 RGD:4889549 NCBI chr 7:24,086,138...24,089,364
Ensembl chr 7:24,086,218...24,089,370 		JBrowse link
G FDX1 ferredoxin 1 ISO RGD PMID:18821018 RGD:2325883 NCBI chr 9:38,376,147...38,399,026
Ensembl chr 9:38,375,984...38,404,832 		JBrowse link
G FDXR ferredoxin reductase ISO RGD PMID:18821018 RGD:2325883 NCBI chr12:6,372,224...6,382,769
Ensembl chr12:6,372,009...6,382,769 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:17926129 RGD:4892309 NCBI chr 3:10,212,734...10,272,184
Ensembl chr 3:10,212,735...10,281,823 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:18821018 RGD:2325883 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    classic metabolic pathway 1013
      lipid metabolic pathway 257
        isoprenoid metabolic pathway 60
          isoprenoid biosynthetic pathway 45
            steroid biosynthetic pathway 45
              steroid hormone biosynthetic pathway 21
                C21-steroid hormone biosynthetic pathway 9
                  mineralocorticoid biosynthetic pathway 6
                    aldosterone biosynthetic pathway 6
paths to the root