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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:drug pathway
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Accession:PW:0000754 term browser browse the term
Definition:The pharmacokinetics and the pharmacodynamics pathway elicited by the administration of specific drugs. The systems involved in drug processing and responses are also those handling exogenous, xenobiotic compounds in the cellular detoxification pathway. The distinction between a random encounter with a foreign compound and the processing of a substance administered for treatment along with the importance of genetic variation for the individual responses to particular drugs warrant their separate consideration.

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abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr16:62,001,082...62,019,470
Ensembl chr16:62,001,352...62,019,289 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
acebutolol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00296 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00296 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00296 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00296 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00296 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00296 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00296 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00296 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00296 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00296 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00296 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00296
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00296 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00296 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00296 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00296 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00296 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00296 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00296 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00296 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00296 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00296 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00296 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00296 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00296 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00296 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00296 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00296 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00296 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00296 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00296 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00296 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00296 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00296 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00296 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00296 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00296 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00296 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00296 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00296 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00296 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00296 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00296 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00296 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00296 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00296 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00296 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00296 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00296 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00296 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00296 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00296 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00296 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00296 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00296 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00296 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00269 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00269 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00083 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00083 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00083 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00083 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00083 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00083 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
adefovir pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK1 adenylate kinase 1 ISO SMPDB SMP:00629 NCBI chr12:10,251,793...10,261,635
Ensembl chr12:10,256,054...10,261,465 		JBrowse link
G AK2 adenylate kinase 2 ISO SMPDB SMP:00629 NCBI chr20:99,834,286...99,863,071
Ensembl chr20:99,834,334...99,858,781 		JBrowse link
G LOC103242911 nucleoside diphosphate kinase B ISO SMPDB SMP:00629 NCBI chr16:42,176,690...42,182,041
Ensembl chr16:42,176,524...42,182,019 		JBrowse link
G LOC103242912 nucleoside diphosphate kinase A ISO SMPDB SMP:00629 NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616 		JBrowse link
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00296 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00296 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD
SMPDB		 PMID:19127141 RGD:4140443 SMP:00296 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:18426615 PMID:19127141 RGD:4140443 RGD:4140444 NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00296 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00296 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00296 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00296 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00296 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00296 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00296 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00296 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00296
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00296 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00296 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00296 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00296 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00296 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00296 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00296 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00296 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00296 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00296 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00296 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00296 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00296 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00296 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00296 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00296 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00296 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00296 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00296 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00296 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00296 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00296 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00296 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00296 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00296 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00296 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00296 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00296 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00296 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00296 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00296 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00296 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00296 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00296 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00296 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00296 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00296 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00296 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00296 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00296 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00296 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00296 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00296 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00296 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00296 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
alendronate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 ISO SMPDB SMP:00095 NCBI chr13:87,363,527...87,378,002 JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO SMPDB SMP:00095 NCBI chr21:56,865,498...56,888,196
Ensembl chr21:56,865,312...56,886,698 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase ISO SMPDB SMP:00095 NCBI chr20:78,052,565...78,088,918
Ensembl chr20:78,052,607...78,086,303 		JBrowse link
G EBP EBP cholestenol delta-isomerase ISO SMPDB SMP:00095 NCBI chr  X:45,652,398...45,660,551
Ensembl chr  X:45,653,356...45,660,291 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 ISO SMPDB SMP:00095 NCBI chr 8:7,272,580...7,306,859
Ensembl chr 8:7,271,509...7,306,760 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO SMPDB SMP:00095 NCBI chr20:8,514,311...8,526,363 JBrowse link
G GGPS1 geranylgeranyl diphosphate synthase 1 ISO SMPDB SMP:00095 NCBI chr25:72,502,333...72,517,349 JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO SMPDB SMP:00095 NCBI chr 4:69,664,784...69,690,343
Ensembl chr 4:69,665,417...69,688,686 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO SMPDB SMP:00095 NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 ISO SMPDB SMP:00095 NCBI chr20:1,271,259...1,289,232
Ensembl chr20:1,273,052...1,288,930 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 ISO SMPDB SMP:00095 NCBI chr 9:995,608...1,011,226
Ensembl chr 9:996,909...1,003,963 		JBrowse link
G LIPA lipase A, lysosomal acid type ISO SMPDB SMP:00095 NCBI chr 9:82,639,220...82,677,479
Ensembl chr 9:82,638,621...82,677,488 		JBrowse link
G LSS lanosterol synthase ISO SMPDB SMP:00095 NCBI chr 2:89,809,065...89,846,295
Ensembl chr 2:89,811,698...89,846,242 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 ISO SMPDB SMP:00095 NCBI chr 7:111,688,591...111,704,765
Ensembl chr 7:111,688,604...111,704,849 		JBrowse link
G MVD mevalonate diphosphate decarboxylase ISO SMPDB SMP:00095 NCBI chr 5:74,031,470...74,049,066
Ensembl chr 5:74,031,316...74,049,011 		JBrowse link
G MVK mevalonate kinase ISO SMPDB SMP:00095 NCBI chr11:104,812,882...104,837,089
Ensembl chr11:104,813,846...104,835,517 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like ISO SMPDB SMP:00095 NCBI chr  X:127,342,788...127,389,117
Ensembl chr  X:127,342,850...127,390,536 		JBrowse link
G PMVK phosphomevalonate kinase ISO SMPDB SMP:00095 NCBI chr20:8,893,297...8,906,882
Ensembl chr20:8,894,786...8,906,873 		JBrowse link
G SC5D sterol-C5-desaturase ISO SMPDB SMP:00095 NCBI chr 1:112,706,511...112,720,860
Ensembl chr 1:112,706,545...112,719,722 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 ISO SMPDB SMP:00095 NCBI chr25:49,998,197...50,061,433
Ensembl chr25:50,001,910...50,061,173 		JBrowse link
G SQLE squalene epoxidase ISO SMPDB SMP:00095 NCBI chr 8:119,586,639...119,610,980
Ensembl chr 8:119,586,659...119,611,142 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 ISO SMPDB SMP:00095 NCBI chr 1:9,112,528...9,117,201
Ensembl chr 1:9,112,710...9,116,898 		JBrowse link
alfentanil pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00413 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00413 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00413 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00413 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00413 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00413 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00413 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00413 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00413
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00413 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00413 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00413 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00413 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00413 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00413 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00413 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00413 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00413 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00413 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00413 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00413 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00413 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00413 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00413 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00413 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00413 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00413 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00413 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00413 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00413 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00280 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00280 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
amiloride pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) ISO SMPDB SMP:00133 NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728 		JBrowse link
G AQP2 aquaporin 2 ISO SMPDB SMP:00133 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) ISO SMPDB SMP:00133 NCBI chr12:46,817,790...46,825,154 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00133 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00133 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00133 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00133 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00133 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00133 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00133 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00133
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00133 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 ISO SMPDB SMP:00133 NCBI chr 7:94,574,010...94,935,348 JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO SMPDB SMP:00133 NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta ISO SMPDB SMP:00133 NCBI chr 5:21,021,181...21,107,746
Ensembl chr 5:21,022,133...21,107,824 		JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta ISO SMPDB SMP:00133 NCBI chr20:130,158,282...130,169,479 JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma ISO SMPDB SMP:00133 NCBI chr 5:20,860,062...20,924,628
Ensembl chr 5:20,891,416...20,924,819 		JBrowse link
G SLC12A1 solute carrier family 12 member 1 ISO SMPDB SMP:00133 NCBI chr26:34,974,947...35,077,241
Ensembl chr26:34,976,126...35,075,186 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 ISO SMPDB SMP:00133 NCBI chr 5:42,808,773...42,877,714
Ensembl chr 5:42,811,597...42,862,002 		JBrowse link
G SLC12A6 solute carrier family 12 member 6 ISO SMPDB SMP:00133 NCBI chr26:48,570,399...48,673,935
Ensembl chr26:48,589,770...48,674,486 		JBrowse link
G SLC14A2 solute carrier family 14 member 2 ISO SMPDB SMP:00133 NCBI chr18:35,209,672...35,684,142
Ensembl chr18:35,209,267...35,404,626 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 ISO SMPDB SMP:00133 NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO SMPDB SMP:00133 NCBI chr13:87,835,077...87,881,410
Ensembl chr13:87,833,430...87,881,081 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO SMPDB SMP:00133 NCBI chr 1:10,918,081...10,926,790
Ensembl chr 1:10,918,770...10,925,983 		JBrowse link
G SLC38A4 solute carrier family 38 member 4 ISO SMPDB SMP:00133 NCBI chr11:42,965,744...43,035,055
Ensembl chr11:42,963,599...43,005,300 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 ISO SMPDB SMP:00133 NCBI chr14:62,924,906...62,971,268
Ensembl chr14:62,925,443...62,971,252 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 ISO SMPDB SMP:00133 NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298 		JBrowse link
G SLC6A20 solute carrier family 6 member 20 ISO SMPDB SMP:00133 NCBI chr22:7,228,039...7,265,441
Ensembl chr22:7,228,517...7,265,031 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO SMPDB SMP:00133 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SLC7A6 solute carrier family 7 member 6 ISO SMPDB SMP:00133 NCBI chr 5:59,118,131...59,164,659
Ensembl chr 5:59,119,827...59,143,982 		JBrowse link
G SLC7A7 solute carrier family 7 member 7 ISO SMPDB SMP:00133 NCBI chr29:23,135,583...23,183,472
Ensembl chr29:23,139,267...23,180,966 		JBrowse link
G SLC7A8 solute carrier family 7 member 8 ISO SMPDB SMP:00133 NCBI chr29:23,493,987...23,556,834
Ensembl chr29:23,493,715...23,556,857 		JBrowse link
G SLC7A9 solute carrier family 7 member 9 ISO SMPDB SMP:00133 NCBI chr 6:27,877,089...27,919,268
Ensembl chr 6:27,876,364...27,908,098 		JBrowse link
aminocaproic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00286 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00286 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00286 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00286 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00286 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00286 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00286 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00286 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00286 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00286 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00286 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00286 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00286 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00286 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00286 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00286 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00286 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00286 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00286 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
amiodarone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00665 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00665 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00665 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00665 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00665 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00665 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00665 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00665 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00665 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00665 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00665 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00665
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00665 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00665 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00665 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00665 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00665 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00665 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00665 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00665 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00665 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00665 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00665 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00665 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00665 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00665 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00665 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00665 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00665 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00665 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00665 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00665 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00665 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00665 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00665 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00665 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00665 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00665 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00665 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00665 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00665 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00665 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00665 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00665 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00665 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00665 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00665 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00665 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00665 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00665 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00665 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00665 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00665 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00665 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00665 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00665 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00665 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00665 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00665 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
amlodipine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00376 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00376 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00376 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00376 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00376 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00376 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00376 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00376 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00376 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00376 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00376 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00376
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00376 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00376 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00376 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00376 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00376 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00376 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00376 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00376 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00376 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00376 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00376 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00376 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00376 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00376 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00376 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00376 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00376 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00376 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00376 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00376 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00376 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00376 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00376 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00376 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00376 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00376 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00376 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00376 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00376 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00376 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00376 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00376 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00376 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00376 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00376 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00376 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00376 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00376 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00376 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00376 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00376 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00376 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00376 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00376 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00376 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00376 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00376 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00281 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00281 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
antipyrine drug pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00692 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00692 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00692 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00692 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00692 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00692 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00692 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00692 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00692 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00692 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00692 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00692 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00692 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00692
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00692 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00692 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00692 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00692 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00692 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00692 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00692 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00692 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00692 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00692 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00692 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00692 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
aprotinin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00288 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00288 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00288 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00288 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00288 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00288 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00288 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00288 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00288 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00288 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00288 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00288 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00288 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00288 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00288 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00288 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00288 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00288 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00288 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00276 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
aromatase inhibitor pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:18695261 RGD:5130880 NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277 		JBrowse link
artemether pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO SMPDB SMP:00651 NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00651 NCBI chr28:13,297,566...13,330,023 JBrowse link
atenolol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00298 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00298 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00298 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00298 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00298 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00298 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00298 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00298 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00298 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00298 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00298 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00298
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00298 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00298 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00298 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00298 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00298 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00298 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00298 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00298 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00298 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00298 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00298 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00298 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00298 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00298 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00298 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00298 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00298 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00298 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00298 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00298 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00298 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00298 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00298 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00298 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00298 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00298 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00298 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00298 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00298 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00298 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00298 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00298 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00298 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00298 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00298 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00298 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00298 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00298 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00298 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00298 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00298 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00298 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00298 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00298 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00298 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00298 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00298 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
axitinib pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 ISO RGD PMID:22170007 RGD:6907361 NCBI chr23:82,328,257...82,373,785
Ensembl chr23:82,328,258...82,357,044 		JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:22170007 RGD:6907361 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
axitinib pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:22170007 RGD:6907361 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:22170007 RGD:6907361 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO RGD PMID:22170007 RGD:6907361 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 ISO RGD PMID:22170007 RGD:6907361 NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO RGD PMID:22170007 RGD:6907361 NCBI chr28:13,297,566...13,330,023 JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 ISO RGD PMID:22170007 RGD:6907361 NCBI chr11:20,992,353...21,091,761
Ensembl chr11:21,001,655...21,093,278 		JBrowse link
azathioprine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) ISO SMPDB SMP:00427 NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 ISO SMPDB SMP:00427 NCBI chr15:5,409,921...5,505,334
Ensembl chr15:5,409,861...5,505,315 		JBrowse link
G ADA adenosine deaminase ISO SMPDB SMP:00427 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADCY10 adenylate cyclase 10 ISO SMPDB SMP:00427 NCBI chr25:61,129,837...61,228,180
Ensembl chr25:61,140,293...61,230,117 		JBrowse link
G ADK adenosine kinase ISO SMPDB SMP:00427 NCBI chr 9:56,659,284...57,222,279
Ensembl chr 9:56,660,129...57,222,147 		JBrowse link
G ADSL adenylosuccinate lyase ISO SMPDB SMP:00427 NCBI chr19:22,920,971...22,940,468 JBrowse link
G ADSS2 adenylosuccinate synthase 2 ISO SMPDB SMP:00427 NCBI chr25:81,441,792...81,485,344
Ensembl chr25:81,442,787...81,485,292 		JBrowse link
G AK1 adenylate kinase 1 ISO SMPDB SMP:00427 NCBI chr12:10,251,793...10,261,635
Ensembl chr12:10,256,054...10,261,465 		JBrowse link
G AMPD1 adenosine monophosphate deaminase 1 ISO SMPDB SMP:00427 NCBI chr20:18,973,547...18,996,082
Ensembl chr20:18,974,204...18,996,293 		JBrowse link
G APRT adenine phosphoribosyltransferase ISO SMPDB SMP:00427 NCBI chr 5:74,196,858...74,199,789
Ensembl chr 5:74,194,013...74,199,891 		JBrowse link
G ATAD1 ATPase family AAA domain containing 1 ISO SMPDB SMP:00427 NCBI chr 9:81,197,332...81,285,279 JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO SMPDB SMP:00427 NCBI chr10:101,128,583...101,166,668 JBrowse link
G DGUOK deoxyguanosine kinase ISO SMPDB SMP:00427 NCBI chr14:33,320,957...33,356,088
Ensembl chr14:33,320,969...33,356,093 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) ISO SMPDB SMP:00427 NCBI chr24:51,176,137...51,234,575
Ensembl chr24:51,181,859...51,231,078 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 ISO SMPDB SMP:00427 NCBI chr12:752,258...758,148
Ensembl chr12:752,774...757,614 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO SMPDB SMP:00427 NCBI chr 2:58,641,566...58,682,014
Ensembl chr 2:58,643,877...58,683,023 		JBrowse link
G GDA guanine deaminase ISO SMPDB SMP:00427 NCBI chr12:83,195,746...83,305,181
Ensembl chr12:83,195,994...83,306,792 		JBrowse link
G GMPR guanosine monophosphate reductase ISO SMPDB SMP:00427 NCBI chr17:55,843,576...55,893,334
Ensembl chr17:55,840,978...55,893,361 		JBrowse link
G GMPS guanine monophosphate synthase ISO SMPDB SMP:00427 NCBI chr15:34,817,603...34,885,363
Ensembl chr15:34,815,066...34,885,228 		JBrowse link
G GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 ISO SMPDB SMP:00427 NCBI chr 1:98,108,081...98,439,453 JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 ISO SMPDB SMP:00427 NCBI chr 7:102,332,711...102,381,250
Ensembl chr 7:102,332,719...102,381,251 		JBrowse link
G GUK1 guanylate kinase 1 ISO SMPDB SMP:00427 NCBI chr25:1,579,382...1,587,623
Ensembl chr25:1,579,610...1,587,419 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO SMPDB SMP:00427 NCBI chr  X:109,629,674...109,671,409 JBrowse link
G IMPDH1 inosine monophosphate dehydrogenase 1 ISO SMPDB SMP:00427 NCBI chr21:97,188,835...97,231,871
Ensembl chr21:97,189,481...97,206,726 		JBrowse link
G ITPA inosine triphosphatase ISO SMPDB SMP:00427 NCBI chr 2:33,873,231...33,893,329
Ensembl chr 2:33,873,339...33,893,556 		JBrowse link
G LOC103219273 bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] ISO SMPDB SMP:00427 NCBI chr12:46,260,652...46,274,678 JBrowse link
G LOC103221883 uncharacterized LOC103221883 ISO SMPDB SMP:00427 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
G NME6 NME/NM23 nucleoside diphosphate kinase 6 ISO SMPDB SMP:00427 NCBI chr22:9,685,583...9,692,993
Ensembl chr22:9,681,953...9,692,172 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II ISO SMPDB SMP:00427 NCBI chr 9:96,133,873...96,325,122
Ensembl chr 9:96,135,400...96,219,956 		JBrowse link
G NUDT5 nudix hydrolase 5 ISO SMPDB SMP:00427 NCBI chr 9:12,218,466...12,247,129 JBrowse link
G PDE10A phosphodiesterase 10A ISO SMPDB SMP:00427 NCBI chr13:93,012,027...93,684,349
Ensembl chr13:93,020,696...93,344,369 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO SMPDB SMP:00427 NCBI chr16:7,618,952...7,639,700
Ensembl chr16:7,623,817...7,638,594 		JBrowse link
G PNP purine nucleoside phosphorylase ISO SMPDB SMP:00427 NCBI chr29:20,992,892...21,001,400
Ensembl chr29:20,993,280...21,001,606 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO SMPDB SMP:00427 NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488 		JBrowse link
G PRPS1L1 phosphoribosyl pyrophosphate synthetase 1 like 1 ISO SMPDB SMP:00427 NCBI chr21:40,120,251...40,121,975
Ensembl chr21:40,120,963...40,121,919 		JBrowse link
G RAC1 Rac family small GTPase 1 ISO SMPDB SMP:00427 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO SMPDB SMP:00427 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO SMPDB SMP:00427 NCBI chr14:97,512,690...97,519,734
Ensembl chr14:97,512,832...97,521,932 		JBrowse link
G SLC28A2 solute carrier family 28 member 2 ISO SMPDB SMP:00427 NCBI chr26:37,927,200...37,956,729 JBrowse link
G SLC28A3 solute carrier family 28 member 3 ISO SMPDB SMP:00427 NCBI chr12:95,088,902...95,179,201
Ensembl chr12:95,091,301...95,127,745 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) ISO SMPDB SMP:00427 NCBI chr17:27,934,537...27,949,120
Ensembl chr17:27,931,945...27,949,006 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 ISO SMPDB SMP:00427 NCBI chr 1:7,904,813...7,914,344
Ensembl chr 1:7,905,297...7,917,309 		JBrowse link
G TPMT thiopurine S-methyltransferase ISO SMPDB SMP:00427 NCBI chr17:53,987,561...54,012,647
Ensembl chr17:53,987,559...54,014,650 		JBrowse link
G TXN thioredoxin ISO SMPDB SMP:00427 NCBI chr12:29,296,166...29,308,979 JBrowse link
G XDH xanthine dehydrogenase ISO SMPDB SMP:00427 NCBI chr14:76,084,693...76,162,840
Ensembl chr14:76,085,368...76,163,936 		JBrowse link
benazepril pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO SMPDB SMP:00145 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00145 NCBI chr15:41,957,826...42,002,776 JBrowse link
G REN renin ISO SMPDB SMP:00145 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
bendroflumethiazide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) ISO SMPDB SMP:00090 NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728 		JBrowse link
G AQP2 aquaporin 2 ISO SMPDB SMP:00090 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) ISO SMPDB SMP:00090 NCBI chr12:46,817,790...46,825,154 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00090 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00090 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00090 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00090 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00090 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00090 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00090 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00090
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00090 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 ISO SMPDB SMP:00090 NCBI chr 7:94,574,010...94,935,348 JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO SMPDB SMP:00090 NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta ISO SMPDB SMP:00090 NCBI chr 5:21,021,181...21,107,746
Ensembl chr 5:21,022,133...21,107,824 		JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta ISO SMPDB SMP:00090 NCBI chr20:130,158,282...130,169,479 JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma ISO SMPDB SMP:00090 NCBI chr 5:20,860,062...20,924,628
Ensembl chr 5:20,891,416...20,924,819 		JBrowse link
G SLC12A1 solute carrier family 12 member 1 ISO SMPDB SMP:00090 NCBI chr26:34,974,947...35,077,241
Ensembl chr26:34,976,126...35,075,186 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 ISO SMPDB SMP:00090 NCBI chr 5:42,808,773...42,877,714
Ensembl chr 5:42,811,597...42,862,002 		JBrowse link
G SLC12A6 solute carrier family 12 member 6 ISO SMPDB SMP:00090 NCBI chr26:48,570,399...48,673,935
Ensembl chr26:48,589,770...48,674,486 		JBrowse link
G SLC14A2 solute carrier family 14 member 2 ISO SMPDB SMP:00090 NCBI chr18:35,209,672...35,684,142
Ensembl chr18:35,209,267...35,404,626 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 ISO SMPDB SMP:00090 NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO SMPDB SMP:00090 NCBI chr13:87,835,077...87,881,410
Ensembl chr13:87,833,430...87,881,081 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO SMPDB SMP:00090 NCBI chr 1:10,918,081...10,926,790
Ensembl chr 1:10,918,770...10,925,983 		JBrowse link
G SLC38A4 solute carrier family 38 member 4 ISO SMPDB SMP:00090 NCBI chr11:42,965,744...43,035,055
Ensembl chr11:42,963,599...43,005,300 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 ISO SMPDB SMP:00090 NCBI chr14:62,924,906...62,971,268
Ensembl chr14:62,925,443...62,971,252 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 ISO SMPDB SMP:00090 NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298 		JBrowse link
G SLC6A20 solute carrier family 6 member 20 ISO SMPDB SMP:00090 NCBI chr22:7,228,039...7,265,441
Ensembl chr22:7,228,517...7,265,031 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO SMPDB SMP:00090 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G SLC7A6 solute carrier family 7 member 6 ISO SMPDB SMP:00090 NCBI chr 5:59,118,131...59,164,659
Ensembl chr 5:59,119,827...59,143,982 		JBrowse link
G SLC7A7 solute carrier family 7 member 7 ISO SMPDB SMP:00090 NCBI chr29:23,135,583...23,183,472
Ensembl chr29:23,139,267...23,180,966 		JBrowse link
G SLC7A8 solute carrier family 7 member 8 ISO SMPDB SMP:00090 NCBI chr29:23,493,987...23,556,834
Ensembl chr29:23,493,715...23,556,857 		JBrowse link
G SLC7A9 solute carrier family 7 member 9 ISO SMPDB SMP:00090 NCBI chr 6:27,877,089...27,919,268
Ensembl chr 6:27,876,364...27,908,098 		JBrowse link
betaxolol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00299 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00299 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00299 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00299 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00299 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00299 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00299 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00299 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00299 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00299 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00299 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00299
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00299 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00299 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00299 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00299 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00299 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00299 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00299 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00299 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00299 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00299 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00299 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00299 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00299 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00299 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00299 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00299 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00299 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00299 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00299 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00299 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00299 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00299 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00299 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00299 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00299 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00299 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00299 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00299 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00299 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00299 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00299 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00299 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00299 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00299 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00299 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00299 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00299 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00299 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00299 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00299 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00299 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00299 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00299 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00299 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00299 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00299 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00299 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
bevacizumab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 ISO SMPDB SMP:00420 NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967 		JBrowse link
G KDR kinase insert domain receptor ISO SMPDB SMP:00420 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO SMPDB SMP:00420 NCBI chr17:28,377,959...28,394,508 JBrowse link
bisoprolol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00300 NCBI chr 1:47,494,861...47,578,818
Ensembl chr 1:47,494,959...47,578,882 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00300 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00300 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00300 NCBI chr15:41,957,826...42,002,776 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00300 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00300 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00300 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00300 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00300 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00300 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00300 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00300
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00300 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00300 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00300 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00300 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00300 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00300 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00300 NCBI chr24:68,133,446...68,145,117
Ensembl chr24:68,133,428...68,145,180 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00300 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00300 NCBI chr15:89,937,900...90,214,976
Ensembl chr15:90,055,964...90,215,652 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00300 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00300 NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00300 NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00300 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00300 NCBI chr20:21,618,365...21,833,443
Ensembl chr20:21,625,147...21,833,186 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00300 NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00300 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00300 NCBI chr21:119,123,601...119,156,985
Ensembl chr21:119,124,007...119,156,794 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00300 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00300 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00300 NCBI chr16:51,448,821...51,461,801
Ensembl chr16:51,452,567...51,453,850 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00300 NCBI chr10:40,096,042...40,258,641
Ensembl chr10:40,096,527...40,255,646 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00300 NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00300 NCBI chr 1:120,025,238...120,098,006
Ensembl chr 1:120,025,300...120,057,023 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00300 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00300 NCBI chr25:70,820,089...70,873,654
Ensembl chr25:70,819,706...70,873,961 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00300 NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863 		JBrowse link
G LOC103235292 troponin I, cardiac muscle ISO SMPDB SMP:00300 NCBI chr 6:47,746,293...47,752,118
Ensembl chr 6:47,745,386...47,752,204 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00300 NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00300 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00300 NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00300 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00300 NCBI chr16:53,021,666...53,042,594
Ensembl chr16:53,023,963...53,042,493 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00300 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00300 NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00300 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SNTA1 syntrophin alpha 1 ISO SMPDB SMP:00300 NCBI chr 2:37,703,002...37,737,529
Ensembl chr 2:37,702,971...37,737,423 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00300 NCBI chr 8:115,117,224...115,391,475
Ensembl chr 8:115,117,756...115,391,537 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00300 NCBI chr 5:58,096,883...58,220,668 JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00300 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00300 NCBI chr 2:18,051,708...18,063,108
Ensembl chr 2:18,061,492...18,062,971 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00300 NCBI chr25:27,989,743...28,009,234
Ensembl chr25:27,997,709...28,002,646 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00300 NCBI chr 1:1,657,631...1,661,575 JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00300 NCBI chr 6:47,726,049...47,743,465
Ensembl chr 6:47,726,002...47,743,404 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00300 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00300 NCBI chr 1:1,718,729...1,738,271
Ensembl chr 1:1,718,523...1,738,477 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00300 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00300 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277 NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:129,090,140...129,315,343
Ensembl chr  X:129,088,611...129,312,909 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:114,618,397...114,650,827
Ensembl chr  X:114,618,639...114,651,365 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640 		JBrowse link
bumetanide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) ISO SMPDB SMP:00088 NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728 		JBrowse link
G AQP2 aquaporin 2 ISO SMPDB SMP:00088 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) ISO SMPDB SMP:00088 NCBI chr12:46,817,790...46,825,154 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00088 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054