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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:syndecan signaling pathway
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Accession:PW:0000659 term browser browse the term
Definition:Syndecan family of proteoglycans appears to be involved in cell-adhesion, particularly cell-extracellular matrix (ECM) signaling and to integrate with the integrin pathway. They also appear to integrate directional cues important for neuronal migration, axon guidance and synapse formation.
Synonyms:related_synonym: PID:200134;   PID:200156;   PID:200192;   PID:200198

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syndecan signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 ISO PID PID:200134 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555 		JBrowse link
G Adam12 ADAM metallopeptidase domain 12 ISO PID PID:200134 NCBI chr 1:205,951,840...206,286,294
Ensembl chr 1:205,956,342...206,282,575 		JBrowse link
G Agrp agouti related neuropeptide ISO PID PID:200198 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit ISO PID PID:200198 NCBI chr 2:198,006,247...198,009,837
Ensembl chr 2:198,006,316...198,009,830 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO PID PID:200198 NCBI chr 8:72,508,008...72,598,921
Ensembl chr 8:72,476,425...72,629,265 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO PID PID:200192 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bsg basigin (Ok blood group) ISO PID PID:200156 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase ISO PID PID:200156 PID:200192 PID:200198 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155 		JBrowse link
G Casp3 caspase 3 ISO PID PID:200192 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cav2 caveolin 2 ISO PID PID:200192 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO PID PID:200134 PID:200156 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 ISO PID PID:200134 NCBI chr 9:66,059,765...66,153,729
Ensembl chr 9:66,058,047...66,148,087 		JBrowse link
G Col10a1 collagen type X alpha 1 chain ISO PID PID:200156 NCBI chr20:41,180,295...41,190,664
Ensembl chr20:41,184,287...41,189,633 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain ISO PID PID:200156 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain ISO PID PID:200156 NCBI chr20:3,829,324...3,859,022
Ensembl chr20:3,830,164...3,859,018 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain ISO PID PID:200156 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368 		JBrowse link
G Col13a1 collagen type XIII alpha 1 chain ISO PID PID:200156 NCBI chr20:31,456,502...31,598,360
Ensembl chr20:31,456,852...31,598,118 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain ISO PID PID:200156 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain ISO PID PID:200156 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Col16a1 collagen type XVI alpha 1 chain ISO PID PID:200156 NCBI chr 5:148,257,030...148,311,645
Ensembl chr 5:148,257,642...148,311,645 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain ISO PID PID:200156 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO PID PID:200156 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO PID PID:200156 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151 		JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO PID PID:200156 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO PID PID:200156 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO PID PID:200156 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain ISO PID PID:200156 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain ISO PID PID:200156 NCBI chr 9:88,314,763...88,357,183
Ensembl chr 9:88,232,455...88,357,182 		JBrowse link
G Col4a5 collagen type IV alpha 5 chain ISO PID PID:200156 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685 		JBrowse link
G Col4a6 collagen type IV alpha 6 chain ISO PID PID:200156 NCBI chr  X:112,405,647...112,768,337
Ensembl chr  X:112,405,647...112,473,822 		JBrowse link
G Col5a1 collagen type V alpha 1 chain ISO PID PID:200156 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882 		JBrowse link
G Col5a2 collagen type V alpha 2 chain ISO PID PID:200156 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain ISO PID PID:200156 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain ISO PID PID:200156 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain ISO PID PID:200156 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain ISO PID PID:200156 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain ISO PID PID:200156 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891 		JBrowse link
G Col8a2 collagen type VIII alpha 2 chain ISO PID PID:200156 NCBI chr 5:144,308,527...144,335,142
Ensembl chr 5:144,308,611...144,335,172 		JBrowse link
G Col9a1 collagen type IX alpha 1 chain ISO PID PID:200156 NCBI chr 9:30,419,001...30,502,307
Ensembl chr 9:30,419,001...30,502,298 		JBrowse link
G Col9a2 collagen type IX alpha 2 chain ISO PID PID:200156 NCBI chr 5:139,962,684...139,979,865
Ensembl chr 5:139,963,002...139,979,864 		JBrowse link
G Col9a3 collagen type IX alpha 3 chain ISO PID PID:200156 NCBI chr 3:176,102,287...176,124,839
Ensembl chr 3:176,102,351...176,124,306 		JBrowse link
G Csf2 colony stimulating factor 2 ISO PID PID:200192 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Cttn cortactin ISO PID PID:200198 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO PID PID:200134 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO PID PID:200134 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Dnm2 dynamin 2 ISO PID PID:200134 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524 		JBrowse link
G Egfr epidermal growth factor receptor ISO PID PID:200198 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 ISO PID PID:200192 NCBI chr 5:150,081,727...150,243,186
Ensembl chr 5:150,084,611...150,167,077 		JBrowse link
G Ephb2 Eph receptor B2 ISO PID PID:200192 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456 		JBrowse link
G Ezr ezrin ISO PID PID:200192 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G F2 coagulation factor II ISO PID PID:200134 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO PID PID:200134 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgf6 fibroblast growth factor 6 ISO PID PID:200134 NCBI chr 4:159,563,798...159,572,333
Ensembl chr 4:159,563,798...159,572,333 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO PID PID:200134 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Fn1 fibronectin 1 ISO PID PID:200134 PID:200192 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200198 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Fzd7 frizzled class receptor 7 ISO PID PID:200134 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 ISO PID PID:200134 NCBI chr19:24,786,604...24,798,231
Ensembl chr19:24,786,628...24,798,233 		JBrowse link
G Hgf hepatocyte growth factor ISO PID PID:200156 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hpse heparanase ISO PID PID:200156 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO PID PID:200192 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686 		JBrowse link
G Itga2 integrin subunit alpha 2 ISO PID PID:200192 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961 		JBrowse link
G Itga5 integrin subunit alpha 5 ISO PID PID:200134 PID:200192 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652 		JBrowse link
G Itgb1 integrin subunit beta 1 ISO PID PID:200134 PID:200192 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Kng2 kininogen 2 ISO PID PID:200192 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lama1 laminin subunit alpha 1 ISO PID PID:200134 PID:200192 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123 		JBrowse link
G Lama3 laminin subunit alpha 3 ISO PID PID:200134 PID:200192 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838 		JBrowse link
G Lama5 laminin subunit alpha 5 ISO PID PID:200156 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO PID PID:200156 PID:200192 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO PID PID:200156 PID:200192 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO PID PID:200192 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mc4r melanocortin 4 receptor ISO PID PID:200198 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725 		JBrowse link
G Mdk midkine ISO PID PID:200134 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO PID PID:200156 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO PID PID:200156 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO PID PID:200192 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO PID PID:200156 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO PID PID:200134 PID:200156 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Ncan neurocan ISO PID PID:200198 NCBI chr16:21,050,243...21,076,707
Ensembl chr16:21,050,243...21,076,707 		JBrowse link
G Ncstn nicastrin ISO PID PID:200198 NCBI chr13:90,451,046...90,467,256
Ensembl chr13:90,451,044...90,467,256 		JBrowse link
G Nf1 neurofibromin 1 ISO PID PID:200192 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903 		JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 ISO PID PID:200134 NCBI chr10:10,829,866...10,831,782
Ensembl chr10:10,829,867...10,831,782 		JBrowse link
G Plg plasminogen ISO PID PID:200134 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776 		JBrowse link
G Pomc proopiomelanocortin ISO PID PID:200198 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967 		JBrowse link
G Ppib peptidylprolyl isomerase B ISO PID PID:200156 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO PID PID:200156 PID:200192 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860 		JBrowse link
G Prkca protein kinase C, alpha ISO PID PID:200134 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Prkcd protein kinase C, delta ISO PID PID:200134 PID:200192 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Psen1 presenilin 1 ISO PID PID:200198 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit ISO PID PID:200198 NCBI chr 1:89,016,093...89,017,449
Ensembl chr 1:89,016,096...89,017,290 		JBrowse link
G Ptn pleiotrophin ISO PID PID:200198 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID PID:200134 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Rack1 receptor for activated C kinase 1 ISO PID PID:200192 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198 		JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO PID PID:200192 NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426 		JBrowse link
G Rhoa ras homolog family member A ISO PID PID:200134 PID:200192 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Sdc1 syndecan 1 ISO PID PID:200156 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016 		JBrowse link
G Sdc2 syndecan 2 ISO PID PID:200192 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044 		JBrowse link
G Sdc3 syndecan 3 ISO PID PID:200198 NCBI chr 5:148,923,098...148,956,404
Ensembl chr 5:148,923,098...148,956,404 		JBrowse link
G Sdc4 syndecan 4 ISO PID PID:200134 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190 		JBrowse link
G Sdcbp syndecan binding protein ISO PID PID:200134 PID:200156 PID:200192 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200192 PID:200198 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO PID PID:200134 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO PID PID:200156 PID:200192 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Thbs1 thrombospondin 1 ISO PID PID:200134 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Tnc tenascin C ISO PID PID:200134 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B ISO PID PID:200134 PID:200192 NCBI chr10:47,399,834...47,422,907
Ensembl chr10:47,412,582...47,420,951 		JBrowse link
G Trappc4 trafficking protein particle complex subunit 4 ISO PID PID:200192 NCBI chr 8:48,723,755...48,727,182
Ensembl chr 8:48,723,191...48,727,154 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6106
    signaling pathway 2647
      glycoconjugated protein signaling pathway 415
        proteoglycan signaling pathway 136
          syndecan signaling pathway 107
paths to the root