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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:gluconeogenesis pathway
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Accession:PW:0000641 term browser browse the term
Definition:The gluconeogenic pathway involves the synthesis of glucose from noncarbohydrate precursors. They include the glycolysis products pyruvate and lactate, citric acid cycle intermediates and the carbon skeletons of many amino acids.
Synonyms:related_synonym: Gluconeogenesis
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show annotations for term's descendants           Sort by:
gluconeogenesis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 IEA KEGG rno:00010 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 IEA KEGG rno:00010 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IEA KEGG rno:00010 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IEA KEGG rno:00010 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) IEA KEGG rno:00010 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IEA KEGG rno:00010 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Adpgk ADP-dependent glucokinase IEA KEGG rno:00010 NCBI chr 8:59,699,400...59,727,352
Ensembl chr 8:59,699,388...59,727,351 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 IEA KEGG rno:00010 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA KEGG rno:00010 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEA KEGG rno:00010 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 IEA KEGG rno:00010 NCBI chr 1:218,201,443...218,241,410 JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IEA KEGG rno:00010 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEA KEGG rno:00010 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 IEA KEGG rno:00010 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 IEA KEGG rno:00010 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 IEA KEGG rno:00010 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA KEGG rno:00010 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IEA KEGG rno:00010 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO
IEA		 KEGG
SMPDB
RGD		 PMID:5251864 SMP:00128 rno:00010, RGD:2302796 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 ISO SMPDB
RGD		 PMID:5251864 RGD:2302796 SMP:00128 NCBI chr 6:72,939,821...72,941,511
Ensembl chr 6:72,939,788...72,941,709 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO
IEA		 KEGG
RGD		 PMID:5251864 rno:00010, RGD:2302796 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C IEA KEGG rno:00010 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Bpgm bisphosphoglycerate mutase IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase IEA KEGG rno:00010 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase IEA KEGG rno:00010 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Eno1 enolase 1 IMP
IEA
ISO		 KEGG
SMPDB
RGD		 PMID:2966075 SMP:00128 rno:00010, RGD:2302802 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Eno2 enolase 2 IDA
IEA		 KEGG
RGD		 PMID:15720133 rno:00010, RGD:2302795 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eno3 enolase 3 IEA KEGG rno:00010 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 IDA
IEA
ISO		 KEGG
SMPDB
RGD		 PMID:4353083 PMID:11440903 SMP:00128 rno:00010, RGD:2302851, RGD:2302970 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 IDA
IEA		 KEGG
RGD		 PMID:4353083 PMID:11440903 rno:00010, RGD:2302851, RGD:2302970 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 IDA
IEA
ISO		 KEGG
SMPDB
RGD		 PMID:4303362 PMID:4353083 PMID:11440903 SMP:00128 rno:00010, RGD:2302850, RGD:2302851, RGD:2302970 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 IDA RGD PMID:4303362 PMID:4353083 PMID:11440903 RGD:2302850, RGD:2302851, RGD:2302970 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221 		JBrowse link
G Galm galactose mutarotase IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IDA
IEA
ISO		 KEGG
SMPDB
RGD		 PMID:15720133 SMP:00128 rno:00010, RGD:2302795 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gapdh-ps118 Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 118 IEA KEGG rno:00010 NCBI chr18:61,626,988...61,628,224
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gapdhl10 glyceraldehyde-3-phosphate dehydrogenase like 10 IEA KEGG rno:00010 NCBI chr16:15,370,290...15,371,300
Ensembl chr16:15,370,293...15,371,300 		JBrowse link
G Gapdhl3 glyceraldehyde-3-phosphate dehydrogenase like 3 IEA KEGG rno:00010 NCBI chr15:77,324,675...77,471,131 JBrowse link
G Gapdhl9 glyceraldehyde-3-phosphate dehydrogenase like 9 IEA KEGG rno:00010 NCBI chr 2:210,784,633...210,785,652 JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic IEA KEGG rno:00010 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Gck glucokinase IEA KEGG rno:00010 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:2966075 RGD:2302802 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IMP RGD PMID:2966075 RGD:2302802 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpi glucose-6-phosphate isomerase IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Hk1 hexokinase 1 IEA KEGG rno:00010 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hk3 hexokinase 3 IEA KEGG rno:00010 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Ldha lactate dehydrogenase A IEA KEGG rno:00010 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Ldhal1 lactate dehydrogenase A like 1 IEA KEGG rno:00010 NCBI chr 8:30,363,220...30,364,836 JBrowse link
G Ldhal6b lactate dehydrogenase A-like 6B IEA KEGG rno:00010 NCBI chr 1:45,997,845...45,999,268
Ensembl chr 1:45,991,991...45,999,272 		JBrowse link
G Ldhb lactate dehydrogenase B IEA KEGG rno:00010 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Ldhc lactate dehydrogenase C IEA KEGG rno:00010 NCBI chr 1:97,385,984...97,403,382
Ensembl chr 1:97,382,379...97,403,378 		JBrowse link
G Mdh2 malate dehydrogenase 2 ISO SMPDB SMP:00128 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 ISO SMPDB SMP:00128 NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Pank1 pantothenate kinase 1 ISO SMPDB SMP:00128 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829 		JBrowse link
G Pc pyruvate carboxylase ISO
IDA		 SMPDB
RGD		 PMID:18613815 PMID:4353083 PMID:6049928 PMID:5773282 SMP:00128, RGD:2302809, RGD:2302851, RGD:2302971, RGD:2302972 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IMP
ISO
IDA
IEA		 KEGG
SMPDB
RGD		 PMID:2966075 PMID:18613815 PMID:4303362 PMID:4353083 PMID:11440903 More... SMP:00128 rno:00010, RGD:2302802, RGD:2302809, RGD:2302850, RGD:2302851, RGD:2302970, RGD:2302971 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IMP
ISO
IDA
IEA		 KEGG
RGD		 PMID:2966075 PMID:18613815 PMID:4353083 PMID:11440903 PMID:6049928 rno:00010, RGD:2302802, RGD:2302809, RGD:2302851, RGD:2302970, RGD:2302971 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 IEA KEGG rno:00010 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 IEA KEGG rno:00010 NCBI chr 2:229,872,300...229,873,848 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta IEA KEGG rno:00010 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 TAS RGD PMID:15170386 RGD:2302793 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182 		JBrowse link
G Pfkl phosphofructokinase, liver type IEA KEGG rno:00010 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Pfkm phosphofructokinase, muscle IEA KEGG rno:00010 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192 		JBrowse link
G Pfkp phosphofructokinase, platelet IEA KEGG rno:00010 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 ISO
IDA
IEA		 KEGG
SMPDB
RGD		 PMID:18092946 PMID:15720133 SMP:00128 rno:00010, RGD:2302794, RGD:2302795 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 IDA
IMP
IEA		 KEGG
RGD		 PMID:15720133 PMID:3091090 rno:00010, RGD:2302795, RGD:2302860 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 IEA KEGG rno:00010 NCBI chr 2:42,754,605...42,755,929
Ensembl chr 2:42,754,639...42,755,856 		JBrowse link
G Pgk2 phosphoglycerate kinase 2 IEA KEGG rno:00010 NCBI chr 9:20,480,367...20,481,933
Ensembl chr 9:20,480,203...20,571,481 		JBrowse link
G Pgm1 phosphoglucomutase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pklr pyruvate kinase L/R IEA KEGG rno:00010 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 ISO SMPDB SMP:00128 NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO SMPDB SMP:00128 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc37a4 solute carrier family 37 member 4 ISO SMPDB SMP:00128 NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301 		JBrowse link
G Tpi1 triosephosphate isomerase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00128 rno:00010 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpi1l2 triosephosphate isomerase 1 like 2 IEA KEGG rno:00010 NCBI chr17:27,101,431...27,102,823
Ensembl chr17:27,101,431...27,102,809 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      carbohydrate metabolic pathway 526
        glucose metabolic pathway 153
          glycolysis/gluconeogenesis pathway 81
            gluconeogenesis pathway 76
paths to the root