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ONTOLOGY REPORT - ANNOTATIONS


Term:translation initiation pathway
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Accession:PW:0000580 term browser browse the term
Definition:Translation initiation is the first, the rate-limiting and the most regulated step of translation. It involves the formation of a scanning competent small subunit. Upon finding the initiation codon, scanning is stopped, the large 60S subunit joins and an elongation competent 80S ribosome is formed.


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translation initiation pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhx29 DExH-box helicase 29 JBrowse link NW_004955446 12,362,324 12,412,814 RGD:9068941
G Eif1 eukaryotic translation initiation factor 1 JBrowse link NW_004955451 15,978,571 15,980,352 RGD:9068941
G Eif1ax eukaryotic translation initiation factor 1A X-linked JBrowse link NW_004955509 577,975 594,028 RGD:9068941
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link NW_004955482 5,380,121 5,388,588 RGD:9068941
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link NW_004955523 553,356 559,376 RGD:9068941
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link NW_004955464 13,254,228 13,378,832 RGD:9068941
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link NW_004955469 9,328,900 9,334,463 RGD:9068941
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link NW_004955420 23,313,405 23,322,748 RGD:9068941
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link NW_004955466 2,838,785 2,855,443 RGD:9068941
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta JBrowse link NW_004955422 27,245,381 27,263,342 RGD:9068941
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma JBrowse link NW_004955509 4,437,044 4,457,819 RGD:9068941
G Eif3a eukaryotic translation initiation factor 3 subunit A JBrowse link NW_004955431 23,542,842 23,578,892 RGD:9068941
G Eif3b eukaryotic translation initiation factor 3 subunit B JBrowse link NW_004955460 12,918,349 12,941,150 RGD:9068941
G Eif3d eukaryotic translation initiation factor 3 subunit D JBrowse link NW_004955413 23,096,440 23,110,312 RGD:9068941
G Eif3e eukaryotic translation initiation factor 3 subunit E JBrowse link NW_004955417 30,823,555 30,858,975 RGD:9068941
G Eif3f eukaryotic translation initiation factor 3 subunit F JBrowse link NW_004955414 23,805,406 23,812,776 RGD:9068941
G Eif3g eukaryotic translation initiation factor 3 subunit G JBrowse link NW_004955495 1,452,806 1,456,834 RGD:9068941
G Eif3h eukaryotic translation initiation factor 3 subunit H JBrowse link NW_004955417 22,757,781 22,846,349 RGD:9068941
G Eif3i eukaryotic translation initiation factor 3 subunit I JBrowse link NW_004955452 10,588,929 10,595,869 RGD:9068941
G Eif3j eukaryotic translation initiation factor 3 subunit J JBrowse link NW_004955416 11,066,030 11,085,054 RGD:9068941
G Eif3k eukaryotic translation initiation factor 3 subunit K JBrowse link NW_004955468 849,149 858,239 RGD:9068941
G Eif3l eukaryotic translation initiation factor 3 subunit L JBrowse link NW_004955413 24,220,188 24,250,786 RGD:9068941
G Eif3m eukaryotic translation initiation factor 3 subunit M JBrowse link NW_004955476 10,594,670 10,612,448 RGD:9068941
G Eif4a1 eukaryotic translation initiation factor 4A1 JBrowse link NW_004955467 9,344,629 9,351,028 RGD:9068941
G Eif4a2 eukaryotic translation initiation factor 4A2 JBrowse link NW_004955420 20,967,848 20,974,093 RGD:9068941
G Eif4b eukaryotic translation initiation factor 4B JBrowse link NW_004955458 296,242 325,451 RGD:9068941
G Eif4e eukaryotic translation initiation factor 4E JBrowse link NW_004955405 9,122,960 9,159,095 RGD:9068941
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 JBrowse link NW_004955420 23,161,541 23,179,788 RGD:9068941
G Eif4g2 eukaryotic translation initiation factor 4 gamma 2 JBrowse link NW_004955414 26,389,125 26,399,916 RGD:9068941
G Eif4h eukaryotic translation initiation factor 4H JBrowse link NW_004955456 13,699,012 13,710,065 RGD:9068941
G Eif5 eukaryotic translation initiation factor 5 JBrowse link NW_004955538 2,226,493 2,233,275 RGD:9068941
G Eif5b eukaryotic translation initiation factor 5B JBrowse link NW_004955470 5,622,128 5,676,533 RGD:9068941
G Pabpc1 poly(A) binding protein cytoplasmic 1 JBrowse link NW_004955417 15,872,906 15,885,246 RGD:9068941

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  pathway 5435
    regulatory pathway 3344
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1594
        translation pathway 218
          translation initiation pathway 33
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.