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ONTOLOGY REPORT - ANNOTATIONS


Term:translation initiation pathway
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Accession:PW:0000580 term browser browse the term
Definition:Translation initiation is the first, the rate-limiting and the most regulated step of translation. It involves the formation of a scanning competent small subunit. Upon finding the initiation codon, scanning is stopped, the large 60S subunit joins and an elongation competent 80S ribosome is formed.


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translation initiation pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhx29 DExH-box helicase 29 JBrowse link 2 44,787,066 44,837,834 RGD:10044021
G Eif1 eukaryotic translation initiation factor 1 JBrowse link 10 88,227,455 88,229,546 RGD:10002776
G Eif1a eukaryotic translation initiation factor 1A JBrowse link 18 40,586,315 40,598,661 RGD:10002776
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link 12 37,444,136 37,452,391 RGD:10044017
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 6 109,044,830 109,051,254 RGD:10044017
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link 5 135,882,946 135,949,276 RGD:10044017
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 6 26,546,917 26,552,474 RGD:10044017
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:10044017
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:10002776
RGD:10044017
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta JBrowse link 3 150,391,455 150,412,179 RGD:10002776
RGD:10044017
G Eif3a eukaryotic translation initiation factor 3, subunit A JBrowse link 1 282,139,809 282,170,017 RGD:10002776
G Eif3b eukaryotic translation initiation factor 3, subunit B JBrowse link 12 16,285,730 16,310,190 RGD:10002776
G Eif3c eukaryotic translation initiation factor 3, subunit C JBrowse link 1 197,964,406 197,982,917 RGD:10002776
G Eif3d eukaryotic translation initiation factor 3, subunit D JBrowse link 7 119,188,189 119,200,578 RGD:10002776
G Eif3el1 eukaryotic translation initiation factor 3, subunit E-like 1 JBrowse link 13 100,129,757 100,162,596 RGD:10002776
G Eif3f eukaryotic translation initiation factor 3, subunit F JBrowse link 1 173,532,826 173,541,806 RGD:10002776
G Eif3g eukaryotic translation initiation factor 3, subunit G JBrowse link 8 21,911,632 21,915,664 RGD:10002776
G Eif3h eukaryotic translation initiation factor 3, subunit H JBrowse link 6 10,151,732 10,236,677 RGD:10002776
G Eif3i eukaryotic translation initiation factor 3, subunit I JBrowse link 5 147,796,580 147,803,853 RGD:10002776
G Eif3j eukaryotic translation initiation factor 3, subunit J JBrowse link 3 113,976,687 113,998,925 RGD:10002776
G Eif3k eukaryotic translation initiation factor 3, subunit K JBrowse link 1 87,927,142 87,937,033 RGD:10002776
G Eif3l eukaryotic translation initiation factor 3, subunit L JBrowse link 7 120,320,547 120,331,596 RGD:10002776
G Eif3m eukaryotic translation initiation factor 3, subunit M JBrowse link 3 94,990,086 95,007,690 RGD:10002776
G Eif4a1 eukaryotic translation initiation factor 4A1 JBrowse link 10 56,271,257 56,276,764 RGD:10044020
RGD:10044021
G Eif4a2 eukaryotic translation initiation factor 4A2 JBrowse link 11 81,373,047 81,379,680 RGD:10044020
RGD:10044021
G Eif4b eukaryotic translation initiation factor 4B JBrowse link 7 143,679,656 143,701,452 RGD:10044021
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 2 243,819,616 243,853,987 RGD:10002776
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 JBrowse link 1 175,883,362 175,895,510 RGD:10002776
RGD:10044017
G Eif4h eukaryotic translation initiation factor 4H JBrowse link 12 25,093,119 25,109,805 RGD:10044021
G Eif5 eukaryotic translation initiation factor 5 JBrowse link 6 136,002,983 136,011,409 RGD:728212
G Eif5b eukaryotic translation initiation factor 5B JBrowse link 9 44,658,724 44,713,518 RGD:10002776
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 7 75,409,581 75,421,874 RGD:10002776
RGD:10044017

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Term Annotations click to browse term
  pathway 6016
    regulatory pathway 3823
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1709
        translation pathway 252
          translation initiation pathway 32
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.