cytokine and chemokine mediated signaling pathway - Ontology Report

rno:04062

NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969

Adcy2

adenylate cyclase 2

rno:04062

NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236

Adcy3

adenylate cyclase 3

rno:04062

NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686

Adcy4

adenylate cyclase 4

rno:04062

NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108

Adcy5

adenylate cyclase 5

rno:04062

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

Adcy6

adenylate cyclase 6

rno:04062

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

Adcy7

adenylate cyclase 7

rno:04062

NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311

Adcy8

adenylate cyclase 8

rno:04062

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

Adcy9

adenylate cyclase 9

rno:04062

NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066

Akt1

AKT serine/threonine kinase 1

rno:04062

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Akt2

AKT serine/threonine kinase 2

rno:04062

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

Akt3

AKT serine/threonine kinase 3

rno:04062

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Arrb1

arrestin, beta 1

rno:04062

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

Arrb2

arrestin, beta 2

rno:04062

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Bcar1

BCAR1 scaffold protein, Cas family member

rno:04062

NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907

Braf

B-Raf proto-oncogene, serine/threonine kinase

rno:04062

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

Ccl1

C-C motif chemokine ligand 1

rno:04062

NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159

Ccl11

C-C motif chemokine ligand 11

rno:04062

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

Ccl12

C-C motif chemokine ligand 12

rno:04062

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

Ccl17

C-C motif chemokine ligand 17

rno:04062

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

Ccl19

C-C motif chemokine ligand 19

rno:04062

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

Ccl2

C-C motif chemokine ligand 2

rno:04062

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

Ccl20

C-C motif chemokine ligand 20

rno:04062

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

Ccl22

C-C motif chemokine ligand 22

rno:04062

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

Ccl24

C-C motif chemokine ligand 24

rno:04062

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

Ccl25

C-C motif chemokine ligand 25

rno:04062

NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554

Ccl26

C-C motif chemokine ligand 26

rno:04062

NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335

Ccl27

C-C motif chemokine ligand 27

rno:04062

NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506

Ccl28

C-C motif chemokine ligand 28

rno:04062

NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997

Ccl3

C-C motif chemokine ligand 3

rno:04062

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl4

C-C motif chemokine ligand 4

rno:04062

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

Ccl5

C-C motif chemokine ligand 5

rno:04062

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Ccl6

C-C motif chemokine ligand 6

rno:04062

NCBI chr10:68,380,185...68,385,859
Ensembl chr10:68,380,188...68,384,001

Ccl7

C-C motif chemokine ligand 7

rno:04062

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

Ccl9

C-C motif chemokine ligand 9

rno:04062

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

Ccr1

C-C motif chemokine receptor 1

rno:04062

NCBI chr 8:123,556,286...123,561,841

Ccr10

C-C motif chemokine receptor 10

rno:04062

NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988

Ccr1l1

chemokine (C-C motif) receptor 1-like 1

rno:04062

NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687

Ccr2

C-C motif chemokine receptor 2

rno:04062

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

Ccr3

C-C motif chemokine receptor 3

rno:04062

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

Ccr4

C-C motif chemokine receptor 4

rno:04062

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

Ccr5

C-C motif chemokine receptor 5

rno:04062

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

Ccr6

C-C motif chemokine receptor 6

rno:04062

NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603

Ccr7

C-C motif chemokine receptor 7

rno:04062

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

Ccr8

C-C motif chemokine receptor 8

rno:04062

NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629

Ccr9

C-C motif chemokine receptor 9

rno:04062

NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969

Cdc42

cell division cycle 42

rno:04062

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

Chuk

component of inhibitor of nuclear factor kappa B kinase complex

rno:04062

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Crk

CRK proto-oncogene, adaptor protein

rno:04062

NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406

Crkl

CRK like proto-oncogene, adaptor protein

rno:04062

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

Csk

C-terminal Src kinase

rno:04062

NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292

Cx3cl1

C-X3-C motif chemokine ligand 1

rno:04062

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

Cx3cr1

C-X3-C motif chemokine receptor 1

rno:04062

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

Cxcl1

C-X-C motif chemokine ligand 1

rno:04062

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Cxcl10

C-X-C motif chemokine ligand 10

rno:04062

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Cxcl11

C-X-C motif chemokine ligand 11

rno:04062

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

Cxcl12

C-X-C motif chemokine ligand 12

rno:04062

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

Cxcl13

C-X-C motif chemokine ligand 13

rno:04062

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

Cxcl14

C-X-C motif chemokine ligand 14

rno:04062

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

Cxcl16

C-X-C motif chemokine ligand 16

rno:04062

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

Cxcl2

C-X-C motif chemokine ligand 2

rno:04062

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

Cxcl9

C-X-C motif chemokine ligand 9

rno:04062

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

Cxcr3

C-X-C motif chemokine receptor 3

rno:04062

NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969

Cxcr4

C-X-C motif chemokine receptor 4

rno:04062

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

Cxcr5

C-X-C motif chemokine receptor 5

rno:04062

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

Cxcr6

C-X-C motif chemokine receptor 6

rno:04062

NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526

Dock2

dedicator of cytokinesis 2

rno:04062

NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808

Elmo1

engulfment and cell motility 1

rno:04062

NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788

Fgr

FGR proto-oncogene, Src family tyrosine kinase

rno:04062

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

Foxo3

forkhead box O3

rno:04062

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

Gnai1

G protein subunit alpha i1

rno:04062

NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417

Gnai2

G protein subunit alpha i2

rno:04062

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

Gnai3

G protein subunit alpha i3

rno:04062

NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742

Gnb1

G protein subunit beta 1

rno:04062

NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124

Gnb2

G protein subunit beta 2

rno:04062

NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019

Gnb3

G protein subunit beta 3

rno:04062

NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173

Gnb4

G protein subunit beta 4

rno:04062

NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579

Gnb5

G protein subunit beta 5

rno:04062

NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069

Gng10

G protein subunit gamma 10

rno:04062

NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012
Ensembl chr 5:73,856,164...73,863,012

Gng11

G protein subunit gamma 11

rno:04062

NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442

Gng12

G protein subunit gamma 12

rno:04062

NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712

Gng13

G protein subunit gamma 13

rno:04062

NCBI chr10:14,741,179...14,743,083
Ensembl chr10:14,741,239...14,743,083

Gng2

G protein subunit gamma 2

rno:04062

NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183

Gng3

G protein subunit gamma 3

rno:04062

NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603

Gng4

G protein subunit gamma 4

rno:04062

NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254

Gng5

G protein subunit gamma 5

rno:04062

NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513

Gng7

G protein subunit gamma 7

rno:04062

NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240

Gng8

G protein subunit gamma 8

rno:04062

NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371

Gngt1

G protein subunit gamma transducin 1

rno:04062

NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252

Gngt2

G protein subunit gamma transducin 2

rno:04062

NCBI chr10:80,776,003...80,784,235

growth factor receptor bound protein 2

rno:04062

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Grk1

G protein-coupled receptor kinase 1

rno:04062

NCBI chr16:76,122,501...76,135,792
Ensembl chr16:76,123,842...76,135,792

Grk2

G protein-coupled receptor kinase 2

rno:04062

NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582

Grk3

G protein-coupled receptor kinase 3

rno:04062

NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262

Grk4

G protein-coupled receptor kinase 4

rno:04062

NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693

Grk5

G protein-coupled receptor kinase 5

rno:04062

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

Grk6

G protein-coupled receptor kinase 6

rno:04062

NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644

Gsk3a

glycogen synthase kinase 3 alpha

rno:04062

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

Gsk3b

glycogen synthase kinase 3 beta

rno:04062

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Hck

HCK proto-oncogene, Src family tyrosine kinase

rno:04062

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

HRas proto-oncogene, GTPase

rno:04062

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04062

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Ikbkg

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04062

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Itk

IL2-inducible T-cell kinase

rno:04062

NCBI chr10:30,753,344...30,814,685
Ensembl chr10:30,753,344...30,814,685

Janus kinase 2

rno:04062

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Jak3

Janus kinase 3

rno:04062

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

Kras

KRAS proto-oncogene, GTPase

rno:04062

NCBI chr 4:178,185,418...178,218,484

LYN proto-oncogene, Src family tyrosine kinase

rno:04062

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Map2k1

mitogen activated protein kinase kinase 1

rno:04062

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

Mapk1

mitogen activated protein kinase 1

rno:04062

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mapk3

mitogen activated protein kinase 3

rno:04062

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

Ncf1

neutrophil cytosolic factor 1

rno:04062

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

nuclear factor kappa B subunit 1

rno:04062

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nfkbia

NFKB inhibitor alpha

rno:04062

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

Nfkbib

NFKB inhibitor beta

rno:04062

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

Nras

NRAS proto-oncogene, GTPase

rno:04062

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

Pak1

p21 (RAC1) activated kinase 1

rno:04062

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

Pard3

par-3 family cell polarity regulator

rno:04062

NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778

Pf4

platelet factor 4

rno:04062

NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

rno:04062

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

Pik3cb

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

rno:04062

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

Pik3cd

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

rno:04062

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

rno:04062

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Pik3r2

phosphoinositide-3-kinase regulatory subunit 2

rno:04062

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

Pik3r3

phosphoinositide-3-kinase regulatory subunit 3

rno:04062

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

Pik3r5

phosphoinositide-3-kinase, regulatory subunit 5

rno:04062

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Plcb1

phospholipase C beta 1

rno:04062

NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869

Plcb2

phospholipase C, beta 2

rno:04062

NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302

Plcb3

phospholipase C beta 3

rno:04062

NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228

Plcb4

phospholipase C, beta 4

rno:04062

NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392

Ppbp

pro-platelet basic protein

rno:04062

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

Prex1

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

rno:04062

NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688

Prkaca

protein kinase cAMP-activated catalytic subunit alpha

rno:04062

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

Prkacb

protein kinase cAMP-activated catalytic subunit beta

rno:04062

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

Prkcb

protein kinase C, beta

rno:04062

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Prkcd

protein kinase C, delta

rno:04062

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

Prkcz

protein kinase C, zeta

rno:04062

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Prkx

protein kinase cAMP-dependent X-linked catalytic subunit

rno:04062

NCBI chr X:41,823,349...41,866,844
Ensembl chr X:41,823,355...41,866,669

Ptk2

protein tyrosine kinase 2

rno:04062

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

Ptk2b

protein tyrosine kinase 2 beta

rno:04062

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

Pxn

paxillin

rno:04062

NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931

Rac1

Rac family small GTPase 1

rno:04062

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Rac2

Rac family small GTPase 2

rno:04062

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

Raf1

Raf-1 proto-oncogene, serine/threonine kinase

rno:04062

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rap1a

RAP1A, member of RAS oncogene family

rno:04062

NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501

Rap1b

RAP1B, member of RAS oncogene family

rno:04062

NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370

Rasgrp2

RAS guanyl releasing protein 2

rno:04062

NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993

RELA proto-oncogene, NF-kB subunit

rno:04062

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Rhoa

ras homolog family member A

rno:04062

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

Rock1

Rho-associated coiled-coil containing protein kinase 1

rno:04062

NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571

Rock2

Rho-associated coiled-coil containing protein kinase 2

rno:04062

NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031

RSA-14-44

RSA-14-44 protein

rno:04062

NCBI chr 4:95,251,657...95,253,029
Ensembl chr 4:95,251,610...95,253,088

SHC adaptor protein 1

rno:04062

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

Shc2

SHC adaptor protein 2

rno:04062

NCBI chr 7:10,066,705...10,088,926
Ensembl chr 7:10,066,705...10,088,926

Shc3

SHC adaptor protein 3

rno:04062

NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710

Shc4

SHC adaptor protein 4

rno:04062

NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366

SOS Ras/Rac guanine nucleotide exchange factor 1

rno:04062

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

Sos2

SOS Ras/Rho guanine nucleotide exchange factor 2

rno:04062

NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692

signal transducer and activator of transcription 1

rno:04062

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Stat2

signal transducer and activator of transcription 2

rno:04062

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

signal transducer and activator of transcription 3

rno:04062

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

signal transducer and activator of transcription 5B

rno:04062

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Tiam1

TIAM Rac1 associated GEF 1

rno:04062

NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901

Vav1

vav guanine nucleotide exchange factor 1

rno:04062

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

Vav2

vav guanine nucleotide exchange factor 2

rno:04062

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

Vav3

vav guanine nucleotide exchange factor 3

rno:04062

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

Was

WASP actin nucleation promoting factor

rno:04062

NCBI chr X:14,405,105...14,413,850
Ensembl chr X:14,405,124...14,413,849

Wasl

WASP like actin nucleation promoting factor

rno:04062

NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022

Xcl1

X-C motif chemokine ligand 1

rno:04062

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

Xcr1

X-C motif chemokine receptor 1

rno:04062

NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226

cytokine mediated signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ackr3

atypical chemokine receptor 3

rno:04060

NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237

Acvr1

activin A receptor type 1

rno:04060

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

Acvr1b

activin A receptor type 1B

rno:04060

NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673

Acvr2a

activin A receptor type 2A

rno:04060

NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968

Acvr2b

activin A receptor type 2B

rno:04060

NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458

Amh

anti-Mullerian hormone

rno:04060

NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282

Amhr2

anti-Mullerian hormone receptor type 2

rno:04060

NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258

Bmpr1a

bone morphogenetic protein receptor type 1A

rno:04060

NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616

Bmpr1b

bone morphogenetic protein receptor type 1B

rno:04060

NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368

Bmpr2

bone morphogenetic protein receptor type 2

rno:04060

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

Ccl12

C-C motif chemokine ligand 12

rno:04060

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

Ccl20

C-C motif chemokine ligand 20

rno:04060

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

Ccl22

C-C motif chemokine ligand 22

rno:04060

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

Ccl25

C-C motif chemokine ligand 25

rno:04060

NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554

Ccl28

C-C motif chemokine ligand 28

rno:04060

NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997

Ccl3

C-C motif chemokine ligand 3

rno:04060

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl4

C-C motif chemokine ligand 4

rno:04060

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

Ccl5

C-C motif chemokine ligand 5

rno:04060

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Ccr1

C-C motif chemokine receptor 1

rno:04060

NCBI chr 8:123,556,286...123,561,841

Ccr10

C-C motif chemokine receptor 10

rno:04060

NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988

Ccr1l1

chemokine (C-C motif) receptor 1-like 1

rno:04060

NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687

Ccr2

C-C motif chemokine receptor 2

rno:04060

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

Ccr3

C-C motif chemokine receptor 3

rno:04060

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

Ccr4

C-C motif chemokine receptor 4

rno:04060

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

Ccr5

C-C motif chemokine receptor 5

rno:04060

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

Ccr6

C-C motif chemokine receptor 6

rno:04060

NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603

Ccr7

C-C motif chemokine receptor 7

rno:04060

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

Ccr8

C-C motif chemokine receptor 8

rno:04060

NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629

Ccr9

C-C motif chemokine receptor 9

rno:04060

NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969

Cd27

CD27 molecule

rno:04060

NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592

Cd40

CD40 molecule

rno:04060

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

Cd40lg

CD40 ligand

rno:04060

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

Cd70

Cd70 molecule

rno:04060

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

Clcf1

cardiotrophin-like cytokine factor 1

rno:04060

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

Cntf

ciliary neurotrophic factor

rno:04060

NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877

Cntfr

ciliary neurotrophic factor receptor

rno:04060

NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392

Crlf2

cytokine receptor-like factor 2

rno:04060

NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642

Csf1

colony stimulating factor 1

rno:04060

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

Csf1r

colony stimulating factor 1 receptor

rno:04060

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

Csf2

colony stimulating factor 2

rno:04060

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

Csf2ra

colony stimulating factor 2 receptor subunit alpha

rno:04060

NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128

colony stimulating factor 2 receptor subunit beta

rno:04060

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

Csf3

colony stimulating factor 3

rno:04060

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

Csf3r

colony stimulating factor 3 receptor

rno:04060

NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881

Ctf1

cardiotrophin 1

rno:04060

NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335

Cx3cl1

C-X3-C motif chemokine ligand 1

rno:04060

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

Cx3cr1

C-X3-C motif chemokine receptor 1

rno:04060

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

Cxcl10

C-X-C motif chemokine ligand 10

rno:04060

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Cxcl11

C-X-C motif chemokine ligand 11

rno:04060

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

Cxcl12

C-X-C motif chemokine ligand 12

rno:04060

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

Cxcl13

C-X-C motif chemokine ligand 13

rno:04060

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

Cxcl14

C-X-C motif chemokine ligand 14

rno:04060

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

Cxcl16

C-X-C motif chemokine ligand 16

rno:04060

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

Cxcl2

C-X-C motif chemokine ligand 2

rno:04060

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

Cxcl9

C-X-C motif chemokine ligand 9

rno:04060

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

Cxcr3

C-X-C motif chemokine receptor 3

rno:04060

NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969

Cxcr4

C-X-C motif chemokine receptor 4

rno:04060

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

Cxcr5

C-X-C motif chemokine receptor 5

rno:04060

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

Cxcr6

C-X-C motif chemokine receptor 6

rno:04060

NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526

Eda

ectodysplasin-A

rno:04060

NCBI chr X:65,078,454...65,480,172
Ensembl chr X:65,078,673...65,480,172

Eda2r

ectodysplasin A2 receptor

rno:04060

NCBI chr X:62,224,763...62,269,333
Ensembl chr X:62,228,229...62,269,268

Edar

ectodysplasin-A receptor

rno:04060

NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494

Egf

epidermal growth factor

rno:04060

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

Egfr

epidermal growth factor receptor

rno:04060

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

Epo

erythropoietin

rno:04060

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

Epor

erythropoietin receptor

rno:04060

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

Fas

Fas cell surface death receptor

rno:04060

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

Faslg

Fas ligand

rno:04060

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

Flt1

Fms related receptor tyrosine kinase 1

rno:04060

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

Flt3

Fms related receptor tyrosine kinase 3

rno:04060

NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474

Flt4

Fms related receptor tyrosine kinase 4

rno:04060

NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770

Ghr

growth hormone receptor

rno:04060

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

Hgf

hepatocyte growth factor

rno:04060

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

Ifna1

interferon, alpha 1

rno:04060

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

Ifna2

interferon alpha 2

rno:04060

NCBI chr 5:103,258,617...103,259,195

Ifna4

interferon, alpha 4

rno:04060

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

Ifna4l1

interferon, alpha 4 like 1

rno:04060

NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302

Ifna5

interferon, alpha 5

rno:04060

NCBI chr 5:103,187,852...103,188,430

Ifnar1

interferon alpha and beta receptor subunit 1

rno:04060

NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979

Ifnb1

interferon beta 1

rno:04060

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

interferon gamma

rno:04060

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Ifngr1

interferon gamma receptor 1

rno:04060

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

Ifngr2

interferon gamma receptor 2

rno:04060

NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005

Ifnk

interferon kappa

rno:04060

NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281

Ifnlr1

interferon, lambda receptor 1

rno:04060

NCBI chr 5:147,919,547...147,942,328
Ensembl chr 5:147,919,908...147,942,332

Il10

interleukin 10

rno:04060

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il10ra

interleukin 10 receptor subunit alpha

rno:04060

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

Il10rb

interleukin 10 receptor subunit beta

rno:04060

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

Il11

interleukin 11

rno:04060

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

Il11ra1

interleukin 11 receptor subunit alpha 1

rno:04060

NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408

Il12a

interleukin 12A

rno:04060

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

interleukin 12B

rno:04060

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

interleukin 12 receptor subunit beta 1

rno:04060

NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769

Il12rb2

interleukin 12 receptor subunit beta 2

rno:04060

NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289

Il13

interleukin 13

rno:04060

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

Il13ra1

interleukin 13 receptor subunit alpha 1

rno:04060

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

Il15

interleukin 15

rno:04060

NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820

Il17b

interleukin 17B

rno:04060

NCBI chr18:55,141,194...55,145,565
Ensembl chr18:55,141,194...55,145,565

Il17ra

interleukin 17 receptor A

rno:04060

NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174

Il17rb

interleukin 17 receptor B

rno:04060

NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125

interleukin 18

rno:04060

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il18r1

interleukin 18 receptor 1

rno:04060

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

Il1a

interleukin 1 alpha

rno:04060

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

interleukin 1 beta

rno:04060

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1r1

interleukin 1 receptor type 1

rno:04060

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

Il1r2

interleukin 1 receptor type 2

rno:04060

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

Il1rap

interleukin 1 receptor accessory protein

rno:04060

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

interleukin 2

rno:04060

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il20ra

interleukin 20 receptor subunit alpha

rno:04060

NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602

Il20rb

interleukin 20 receptor subunit beta

rno:04060

NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942

Il21

interleukin 21

rno:04060

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

Il21r

interleukin 21 receptor

rno:04060

NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522

Il22

interleukin 22

rno:04060

NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186

Il22ra1

interleukin 22 receptor subunit alpha 1

rno:04060

NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296

Il22ra2

interleukin 22 receptor subunit alpha 2

rno:04060

NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844

Il23a

interleukin 23 subunit alpha

rno:04060

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Il23r

interleukin 23 receptor

rno:04060

NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021

Il25

interleukin 25

rno:04060

NCBI chr15:28,408,766...28,412,157
Ensembl chr15:28,408,842...28,411,893

Il2ra

interleukin 2 receptor subunit alpha

rno:04060

NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697

Il2rb

interleukin 2 receptor subunit beta

rno:04060

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

interleukin 2 receptor subunit gamma

rno:04060

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

Il3

interleukin 3

rno:04060

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

Il3ra

interleukin 3 receptor subunit alpha

rno:04060

NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484

Il4

interleukin 4

rno:04060

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il4r

interleukin 4 receptor

rno:04060

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

Il5

interleukin 5

rno:04060

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

Il5ra

interleukin 5 receptor subunit alpha

rno:04060

NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544

Il6

interleukin 6

rno:04060

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Il6r

interleukin 6 receptor

rno:04060

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

Il6st

interleukin 6 cytokine family signal transducer

rno:04060

NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936

Il7

interleukin 7

rno:04060

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

Il7r

interleukin 7 receptor

rno:04060

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

Il9

interleukin 9

rno:04060

NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895

Il9r

interleukin 9 receptor

rno:04060

NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990

Kdr

kinase insert domain receptor

rno:04060

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

Kit

KIT proto-oncogene receptor tyrosine kinase

rno:04060

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

Kitlg

KIT ligand

rno:04060

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

Lep

leptin

rno:04060

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Lepr

leptin receptor

rno:04060

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

Lif

LIF, interleukin 6 family cytokine

rno:04060

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

Lifr

LIF receptor subunit alpha

rno:04060

NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699

Lta

lymphotoxin alpha

rno:04060

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

Ltb

lymphotoxin beta

rno:04060

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

Ltbr

lymphotoxin beta receptor

rno:04060

NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539

Met

MET proto-oncogene, receptor tyrosine kinase

rno:04060

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Mpl

MPL proto-oncogene, thrombopoietin receptor

rno:04060

NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797

Ngfr

nerve growth factor receptor

rno:04060

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

Osm

oncostatin M

rno:04060

NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313

Osmr

oncostatin M receptor

rno:04060

NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262

Pdgfa

platelet derived growth factor subunit A

rno:04060

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

Pdgfra

platelet derived growth factor receptor alpha

rno:04060

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Pdgfrb

platelet derived growth factor receptor beta

rno:04060

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

Pf4

platelet factor 4

rno:04060

NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365

Ppbp

pro-platelet basic protein

rno:04060

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

Prl

prolactin

rno:04060

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

Prlr

prolactin receptor

rno:04060

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

Relt

RELT, TNF receptor

rno:04060

NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196

Tgfb1

transforming growth factor, beta 1

rno:04060

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tgfb2

transforming growth factor, beta 2

rno:04060

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tgfb3

transforming growth factor, beta 3

rno:04060

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

Tgfbr1

transforming growth factor, beta receptor 1

rno:04060

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

Tgfbr2

transforming growth factor, beta receptor 2

rno:04060

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

Tnf

tumor necrosis factor

rno:04060

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tnfrsf11a

TNF receptor superfamily member 11A

rno:04060

NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695

Tnfrsf11b

TNF receptor superfamily member 11B

rno:04060

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

Tnfrsf12a

TNF receptor superfamily member 12A

rno:04060

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

Tnfrsf13b

TNF receptor superfamily member 13B

rno:04060

NCBI chr10:45,801,860...45,824,932
Ensembl chr10:45,801,860...45,822,987

Tnfrsf13c

TNF receptor superfamily member 13C

rno:04060

NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517

Tnfrsf14

TNF receptor superfamily member 14

rno:04060

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

Tnfrsf17

TNF receptor superfamily member 17

rno:04060

NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788

Tnfrsf18

TNF receptor superfamily member 18

rno:04060

NCBI chr 5:166,618,461...166,622,353
Ensembl chr 5:166,618,969...166,622,353

Tnfrsf19

TNF receptor superfamily member 19

rno:04060

NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795

Tnfrsf1a

TNF receptor superfamily member 1A

rno:04060

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

Tnfrsf1b

TNF receptor superfamily member 1B

rno:04060

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

Tnfrsf21

TNF receptor superfamily member 21

rno:04060

NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085

Tnfrsf25

TNF receptor superfamily member 25

rno:04060

NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341

Tnfrsf4

TNF receptor superfamily member 4

rno:04060

NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599

Tnfrsf8

TNF receptor superfamily member 8

rno:04060

NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421

Tnfrsf9

TNF receptor superfamily member 9

rno:04060

NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000

Tnfsf10

TNF superfamily member 10

rno:04060

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

Tnfsf11

TNF superfamily member 11

rno:04060

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

Tnfsf12

TNF superfamily member 12

rno:04060

NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213

Tnfsf13

TNF superfamily member 13

rno:04060

NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042

Tnfsf13b

TNF superfamily member 13b

rno:04060

NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693

Tnfsf14

TNF superfamily member 14

rno:04060

NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216

Tnfsf15

TNF superfamily member 15

rno:04060

NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228

Tnfsf18

TNF superfamily member 18

rno:04060

NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169

Tnfsf4

TNF superfamily member 4

rno:04060

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

Tnfsf8

TNF superfamily member 8

rno:04060

NCBI chr 5:77,250,942...77,277,364
Ensembl chr 5:77,251,373...77,277,421

Tnfsf9

TNF superfamily member 9

rno:04060

NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345

Tpo

thyroid peroxidase

rno:04060

NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199

Tslp

thymic stromal lymphopoietin

rno:04060

NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548

Vegfc

vascular endothelial growth factor C

rno:04060

NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848

Vegfd

vascular endothelial growth factor D

rno:04060

NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295

Xcr1

X-C motif chemokine receptor 1

rno:04060

NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226

erythropoietin signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcl2

BCL2, apoptosis regulator

PID:200183

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

Bcl2l1

Bcl2-like 1

PID:200183

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

Btk

Bruton tyrosine kinase

PID:200183

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Cbl

Cbl proto-oncogene

PID:200183

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

Crkl

CRK like proto-oncogene, adaptor protein

PID:200183

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

Epo

erythropoietin

PID:200183

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

Epor

erythropoietin receptor

PID:200183

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

Gab1

GRB2-associated binding protein 1

PID:200183

NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236

growth factor receptor bound protein 2

PID:200183

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

HRas proto-oncogene, GTPase

PID:200183

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

inositol polyphosphate-5-phosphatase D

PID:200183

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Irs2

insulin receptor substrate 2

PID:200183

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

Janus kinase 2

PID:200183

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

LYN proto-oncogene, Src family tyrosine kinase

PID:200183

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

mitogen activated protein kinase 14

PID:200183

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen-activated protein kinase 8

PID:200183

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

nuclear factor kappa B subunit 1

PID:200183

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

phosphoinositide-3-kinase regulatory subunit 1

PID:200183

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Plcg1

phospholipase C, gamma 1

PID:200183

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

Plcg2

phospholipase C, gamma 2

PID:200183

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

protein tyrosine phosphatase, non-receptor type 11

PID:200183

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

PID:200183

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Rap1a

RAP1A, member of RAS oncogene family

PID:200183

NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501

Rapgef1

Rap guanine nucleotide exchange factor 1

PID:200183

NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984

Sh2b3

SH2B adaptor protein 3

PID:200183

NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616

SHC adaptor protein 1

PID:200183

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

suppressor of cytokine signaling 3

PID:200183

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

SOS Ras/Rac guanine nucleotide exchange factor 1

PID:200183

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

signal transducer and activator of transcription 1

PID:200183

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 5A

PID:200183

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

signal transducer and activator of transcription 5B

PID:200183

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Tec

tec protein tyrosine kinase

PID:200183

NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557

Trpc6

transient receptor potential cation channel, subfamily C, member 6

PID:200183

NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092

Vav2

vav guanine nucleotide exchange factor 2

PID:200183

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

FasL mediated signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akt1

AKT serine/threonine kinase 1

PMID:18090083 PMID:19239902

PID:200080

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Bid

BH3 interacting domain death agonist

IEP
ISO

PID
RGD

PID:200080, RGD:2314002, RGD:4143196

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

Birc2

baculoviral IAP repeat-containing 2

PID:200080

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

Birc3

baculoviral IAP repeat-containing 3

PID:200080

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

Btk

Bruton tyrosine kinase

PID:200080

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Casp3

caspase 3

PMID:18090083 PMID:19239902

PID
RGD

PMID:19239902

PID:200080, RGD:4143196

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

caspase 7

RGD

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

Casp8

caspase 8

IMP
ISO

PID
RGD

PID:200080, RGD:2314002, RGD:4143196

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

Cflar

CASP8 and FADD-like apoptosis regulator

ISO
IEP

PID
RGD

PMID:19239902 PMID:19107989

PID:200080, RGD:4143196, RGD:8662854

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

Chuk

component of inhibitor of nuclear factor kappa B kinase complex

PID:200080

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Cltc

clathrin heavy chain

PID:200080

NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737

Ezr

ezrin

PID:200080

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

Fadd

Fas associated via death domain

PID
RGD

PMID:19239902

PID:200080, RGD:4143196

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Faim2

Fas apoptotic inhibitory molecule 2

PMID:18090083 PMID:19107989 PMID:19239902

PID:200080

NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168

Fas

Fas cell surface death receptor

IEP
ISO

PID
RGD

PID:200080, RGD:2314002, RGD:8662854, RGD:4143196

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

Faslg

Fas ligand

IEP
ISO

PID
RGD

PMID:18090083 PMID:19239902

PID:200080, RGD:2314002, RGD:4143196

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

inhibitor of nuclear factor kappa B kinase subunit beta

PID:200080

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Ikbkg

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

PID:200080

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Map2k6

mitogen-activated protein kinase kinase 6

PID:200080

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

Map2k7

mitogen activated protein kinase kinase 7

PID:200080

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

Map3k1

mitogen-activated protein kinase kinase kinase 1

PID:200080

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

Mapk10

mitogen activated protein kinase 10

PID:200080

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

Mapk11

mitogen-activated protein kinase 11

PID:200080

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen activated protein kinase 14

PID:200080

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen-activated protein kinase 8

PID:200080

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

Mapk9

mitogen-activated protein kinase 9

PID:200080

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Pdpk1

3-phosphoinositide dependent protein kinase-1

PID:200080

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200080

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

Pik3cb

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

PID:200080

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

Pik3cd

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

PID:200080

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

PID:200080

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Pik3r2

phosphoinositide-3-kinase regulatory subunit 2

PID:200080

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

Pik3r3

phosphoinositide-3-kinase regulatory subunit 3

PID:200080

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

Rfc1

replication factor C subunit 1

PID:200080

NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370

Ripk1

receptor interacting serine/threonine kinase 1

PID:200080

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

Smpd1

sphingomyelin phosphodiesterase 1

PID:200080

NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794

Src

SRC proto-oncogene, non-receptor tyrosine kinase

PID:200080

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

Syk

spleen associated tyrosine kinase

PID:200080

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

granulocyte-macrophage colony-stimulating factor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccl2

C-C motif chemokine ligand 2

PID:200019

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

cytokine inducible SH2-containing protein

PID:200019

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

Csf2

colony stimulating factor 2

PID:200019

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

Csf2ra

colony stimulating factor 2 receptor subunit alpha

PID:200019

NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128

colony stimulating factor 2 receptor subunit beta

PID:200019

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

Fos

Fos proto-oncogene, AP-1 transcription factor subunit

PID:200019

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Gab2

GRB2-associated binding protein 2

PID:200019

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

growth factor receptor bound protein 2

PID:200019

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

HRas proto-oncogene, GTPase

PID:200019

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

inhibitor of nuclear factor kappa B kinase subunit beta

PID:200019

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

inositol polyphosphate-5-phosphatase D

PID:200019

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Irf8

interferon regulatory factor 8

PID:200019

NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829

Janus kinase 2

PID:200019

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

LYN proto-oncogene, Src family tyrosine kinase

PID:200019

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Map2k1

mitogen activated protein kinase kinase 1

PID:200019

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

Map2k2

mitogen activated protein kinase kinase 2

PID:200019

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

Mapk1

mitogen activated protein kinase 1

PID:200019

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mapk3

mitogen activated protein kinase 3

PID:200019

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

Nras

NRAS proto-oncogene, GTPase

PID:200019

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

Osm

oncostatin M

PID:200019

NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200019

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200019

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Pim1

Pim-1 proto-oncogene, serine/threonine kinase

PID:200019

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

Prkaca

protein kinase cAMP-activated catalytic subunit alpha

PID:200019

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

Prkacb

protein kinase cAMP-activated catalytic subunit beta

PID:200019

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

protein tyrosine phosphatase, non-receptor type 11

PID:200019

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Raf1

Raf-1 proto-oncogene, serine/threonine kinase

PID:200019

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

SHC adaptor protein 1

PID:200019

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

SOS Ras/Rac guanine nucleotide exchange factor 1

PID:200019

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

signal transducer and activator of transcription 1

PID:200019

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 3

PID:200019

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

signal transducer and activator of transcription 5A

PID:200019

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

signal transducer and activator of transcription 5B

PID:200019

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Syk

spleen associated tyrosine kinase

PID:200019

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Ywhaz

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

PID:200019

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

interleukin-1 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

absent in melanoma 2

RGD

NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975

Casp1

caspase 1

PMID:19302047 PMID:20303873

PID
RGD

PID:200089, RGD:5490210, RGD:5490211

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

Chuk

component of inhibitor of nuclear factor kappa B kinase complex

PID:200089

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Erc1

ELKS/RAB6-interacting/CAST family member 1

PID:200089

NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639

inhibitor of nuclear factor kappa B kinase subunit beta

PID:200089

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Ikbkg

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

PID:200089

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il1a

interleukin 1 alpha

PID
RGD

PID:200089, RGD:5490209

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

interleukin 1 beta

PID
RGD

PID:200089, RGD:5490209

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1r1

interleukin 1 receptor type 1

PMID:20081871 PMID:20967881

PID
RGD

PID:200089, RGD:5490209, RGD:5130945

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

Il1r2

interleukin 1 receptor type 2

PID
RGD

PID:200089, RGD:5490209

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

Il1rap

interleukin 1 receptor accessory protein

RGD

RGD:5490209

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

Il1rn

interleukin 1 receptor antagonist

PID
RGD

PID:200089, RGD:5490209

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

Irak1

interleukin-1 receptor-associated kinase 1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

RGD

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

Irak3

interleukin-1 receptor-associated kinase 3

PID:200089

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Irak4

interleukin-1 receptor-associated kinase 4

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837

Jun

Jun proto-oncogene, AP-1 transcription factor subunit

PID:200089

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Map2k6

mitogen-activated protein kinase kinase 6

PID:200089

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

Map3k3

mitogen activated protein kinase kinase kinase 3

PID:200089

NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848

Map3k7

mitogen activated protein kinase kinase kinase 7

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

mitogen-activated protein kinase 8

PID:200089

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

Myd88

MYD88, innate immune signal transduction adaptor

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

nuclear factor kappa B subunit 1

PID:200089

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nlrp1a

NLR family, pyrin domain containing 1A

RGD

PMID:20303873

RGD:5490211

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

Nlrp3

NLR family, pyrin domain containing 3

PMID:19302047 PMID:20303873

RGD

RGD:5490210, RGD:5490211

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Peli1

pellino E3 ubiquitin protein ligase 1

RGD

NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285

Peli2

pellino E3 ubiquitin protein ligase family member 2

RGD

NCBI chr15:21,393,262...21,537,737
Ensembl chr15:21,393,262...21,535,106

Peli3

pellino E3 ubiquitin protein ligase family member 3

RGD

NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200089

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200089

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Prkci

protein kinase C, iota

PID:200089

NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352

Prkcz

protein kinase C, zeta

PID:200089

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Pycard

PYD and CARD domain containing

PMID:19302047 PMID:20303873

RGD

RGD:5490210, RGD:5490211

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

RELA proto-oncogene, NF-kB subunit

PID:200089

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Sigirr

single Ig and TIR domain containing

RGD

RGD:5490209

NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269

Sqstm1

sequestosome 1

PID:200089

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

Tab1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

Tab2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756

Tab3

TGF-beta activated kinase 1 (MAP3K7) binding protein 3

RGD

PMID:18535784

RGD:5490218

NCBI chr X:49,972,414...50,044,658
Ensembl chr X:49,972,330...50,042,056

Ticam2

TIR domain containing adaptor molecule 2

PID:200089

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

Tollip

toll interacting protein

PID
RGD

PMID:18535784

PID:200089, RGD:5490218

NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625

Traf6

TNF receptor associated factor 6

PMID:20086235 PMID:20967881 PMID:18535784

PID
RGD

PID:200089, RGD:5490215, RGD:5130945, RGD:5490218

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Ube2n

ubiquitin-conjugating enzyme E2N

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355

Ube2v1

ubiquitin conjugating enzyme E2 V1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 3:156,317,339...156,340,198
Ensembl chr 3:156,316,781...156,340,273

Interleukin-10 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il10

interleukin 10

PMID:15032600 PMID:19428551 PMID:21115385

RGD

RGD:1580494, RGD:2311043, RGD:5688379

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il10ra

interleukin 10 receptor subunit alpha

PMID:21115385 PMID:19428551

RGD

RGD:5688379, RGD:2311043

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

Il10rb

interleukin 10 receptor subunit beta

RGD

PMID:21115385

RGD:5688379

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

Janus kinase 1

RGD

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

signal transducer and activator of transcription 1

RGD

PMID:21115385

RGD:5688379

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 3

PMID:21115385 PMID:19428551

RGD

RGD:5688379, RGD:2311043

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

tyrosine kinase 2

RGD

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

interleukin-12 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atf2

activating transcription factor 2

PID:200045

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

B2m

beta-2 microglobulin

PID:200045

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

Ccl3

C-C motif chemokine ligand 3

PID:200045

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl4

C-C motif chemokine ligand 4

PID:200045

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

Ccr5

C-C motif chemokine receptor 5

PID:200045

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

Cd247

Cd247 molecule

PID:200045

NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263

Cd3d

CD3 delta subunit of T-cell receptor complex

PID:200045

NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809

Cd3e

CD3 epsilon subunit of T-cell receptor complex

PID:200045

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

Cd3g

CD3 gamma subunit of T-cell receptor complex

PID:200045

NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147

Cd4

Cd4 molecule

PID:200045

NCBI chr 4:157,668,878...157,695,366

Cd8a

CD8 subunit alpha

PID:200045

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

Cd8b

CD8 subunit beta

PID:200045

NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553

Eomes

eomesodermin

PID:200045

NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316

Faslg

Fas ligand

PID:200045

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

Fos

Fos proto-oncogene, AP-1 transcription factor subunit

PID:200045

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Gadd45b

growth arrest and DNA-damage-inducible, beta

PID:200045

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

Gadd45g

growth arrest and DNA-damage-inducible, gamma

PID:200045

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

Gzma

granzyme A

PID:200045

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

Gzmb

granzyme B

PID:200045

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

Hlx

H2.0-like homeobox

PID:200045

NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750

interferon gamma

PID:200045

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Il12a

interleukin 12A

PID:200045

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

interleukin 12B

PID:200045

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

interleukin 12 receptor subunit beta 1

PID:200045

NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769

Il12rb2

interleukin 12 receptor subunit beta 2

PID:200045

NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289

interleukin 18

PID:200045

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il18r1

interleukin 18 receptor 1

PID:200045

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

Il18rap

interleukin 18 receptor accessory protein

PID:200045

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

interleukin 1 beta

PID:200045

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1r1

interleukin 1 receptor type 1

PID:200045

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

interleukin 2

PID:200045

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il2ra

interleukin 2 receptor subunit alpha

PID:200045

NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697

Il2rb

interleukin 2 receptor subunit beta

PID:200045

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

interleukin 2 receptor subunit gamma

PID:200045

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

Il4

interleukin 4

PID:200045

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Janus kinase 2

PID:200045

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Lck

LCK proto-oncogene, Src family tyrosine kinase

PID:200045

NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794

Map2k3

mitogen activated protein kinase kinase 3

PID:200045

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

Map2k6

mitogen-activated protein kinase kinase 6

PID:200045

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

mitogen activated protein kinase 14

PID:200045

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

Mtor

mechanistic target of rapamycin kinase

PID:200045

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

nuclear factor kappa B subunit 1

PID:200045

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nfkb2

nuclear factor kappa B subunit 2

PID:200045

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

Nos2

nitric oxide synthase 2

PID:200045

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

Ppp3ca

protein phosphatase 3 catalytic subunit alpha

PID:200045

NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974

Ppp3cb

protein phosphatase 3 catalytic subunit beta

PID:200045

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

Ppp3r1

protein phosphatase 3, regulatory subunit B, alpha

PID:200045

NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907

Rab7a

RAB7A, member RAS oncogene family

PID:200045

NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889

RELA proto-oncogene, NF-kB subunit

PID:200045

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Relb

RELB proto-oncogene, NF-kB subunit

PID:200045

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

Ripk2

receptor-interacting serine-threonine kinase 2

PID:200045

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

RT1-CE16

RT1 class I, locus CE16

PID:200045

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

RT1-Da

RT1 class II, locus Da

PID:200045

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

RT1-Db1

RT1 class II, locus Db1

PID:200045

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

Socs1

suppressor of cytokine signaling 1

PID:200045

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

Sphk2

sphingosine kinase 2

PID:200045

NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391

signal transducer and activator of transcription 1

PID:200045

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 3

PID:200045

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

Stat4

signal transducer and activator of transcription 4

PID:200045

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 5A

PID:200045

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat6

signal transducer and activator of transcription 6

PID:200045

NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495

Tbx21

T-box transcription factor 21

PID:200045

NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831

Tyk2

tyrosine kinase 2

PID:200045

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

interleukin-2 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcl2

BCL2, apoptosis regulator

PID:200098

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

Cdk2

cyclin dependent kinase 2

PID:200098

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

cytokine inducible SH2-containing protein

PID:200098

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

Dok2

docking protein 2

PID:200098

NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402

Fos

Fos proto-oncogene, AP-1 transcription factor subunit

PID:200098

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Fyn

FYN proto-oncogene, Src family tyrosine kinase

PID:200098

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

Gab2

GRB2-associated binding protein 2

PID:200098

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

growth factor receptor bound protein 2

PID:200098

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

HRas proto-oncogene, GTPase

PID:200098

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

interferon gamma

PID:200098

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Ikzf3

IKAROS family zinc finger 3

PID:200098

NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591

interleukin 2

PID:200098

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il2ra

interleukin 2 receptor subunit alpha

PID:200098

NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697

Il2rb

interleukin 2 receptor subunit beta

PID:200098

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

interleukin 2 receptor subunit gamma

PID:200098

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

Irs1

insulin receptor substrate 1

PID:200098

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

Irs2

insulin receptor substrate 2

PID:200098

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

Jak1

Janus kinase 1

PID:200098

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

Jak3

Janus kinase 3

PID:200098

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

Jun

Jun proto-oncogene, AP-1 transcription factor subunit

PID:200098

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Lck

LCK proto-oncogene, Src family tyrosine kinase

PID:200098

NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794

Map2k1

mitogen activated protein kinase kinase 1

PID:200098

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

Map2k2

mitogen activated protein kinase kinase 2

PID:200098

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

Mapk1

mitogen activated protein kinase 1

PID:200098

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mapk11

mitogen-activated protein kinase 11

PID:200098

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen activated protein kinase 14

PID:200098

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

Mapk3

mitogen activated protein kinase 3

PID:200098

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

mitogen-activated protein kinase 8

PID:200098

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

Mapk9

mitogen-activated protein kinase 9

PID:200098

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Mapkapk2

MAPK activated protein kinase 2

PID:200098

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

Myc

MYC proto-oncogene, bHLH transcription factor

PID:200098

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

Nras

NRAS proto-oncogene, GTPase

PID:200098

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200098

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200098

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Ppp2r5d

protein phosphatase 2, regulatory subunit B', delta

PID:200098

NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400

Prkcb

protein kinase C, beta

PID:200098

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Prkce

protein kinase C, epsilon

PID:200098

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Ptk2b

protein tyrosine kinase 2 beta

PID:200098

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

protein tyrosine phosphatase, non-receptor type 11

PID:200098

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Raf1

Raf-1 proto-oncogene, serine/threonine kinase

PID:200098

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rasa1

RAS p21 protein activator 1

PID:200098

NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854

Rhoa

ras homolog family member A

PID:200098

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

SHC adaptor protein 1

PID:200098

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

Socs1

suppressor of cytokine signaling 1

PID:200098

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

Socs2

suppressor of cytokine signaling 2

PID:200098

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

suppressor of cytokine signaling 3

PID:200098

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

SOS Ras/Rac guanine nucleotide exchange factor 1

PID:200098

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

Stam

signal transducing adaptor molecule

PID:200098

NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467

Stam2

signal transducing adaptor molecule 2

PID:200098

NCBI chr 3:37,186,145...37,234,810
Ensembl chr 3:37,186,145...37,234,812

signal transducer and activator of transcription 1

PID:200098

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 3

PID:200098

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

signal transducer and activator of transcription 5A

PID:200098

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

signal transducer and activator of transcription 5B

PID:200098

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Syk

spleen associated tyrosine kinase

PID:200098

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

interleukin-23 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alox12b

arachidonate 12-lipoxygenase, 12R type

PID:200154

NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938

Ccl2

C-C motif chemokine ligand 2

PID:200154

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

Cd3e

CD3 epsilon subunit of T-cell receptor complex

PID:200154

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

Cd4

Cd4 molecule

PID:200154

NCBI chr 4:157,668,878...157,695,366

Cxcl1

C-X-C motif chemokine ligand 1

PID:200154

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Cxcl3

C-X-C motif chemokine ligand 3

PID:200154

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

Cxcl9

C-X-C motif chemokine ligand 9

PID:200154

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

interferon gamma

PID:200154

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

interleukin 12B

PID:200154

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

interleukin 12 receptor subunit beta 1

PID:200154

NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769

Il17a

interleukin 17A

PID:200154

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

Il17f

interleukin 17F

PID:200154

NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482

interleukin 18

PID:200154

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il18r1

interleukin 18 receptor 1

PID:200154

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

Il18rap

interleukin 18 receptor accessory protein

PID:200154

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

Il19

interleukin 19

PID:200154

NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473

interleukin 1 beta

PID:200154

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

interleukin 2

PID:200154

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il23a

interleukin 23 subunit alpha

PID:200154

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Il23r

interleukin 23 receptor

PID:200154

NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021

Il24

interleukin 24

PID:200154

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

Il6

interleukin 6

PID:200154

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Itga3

integrin subunit alpha 3

PID:200154

NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118

Janus kinase 2

PID:200154

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Mpo

myeloperoxidase

PID:200154

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

nuclear factor kappa B subunit 1

PID:200154

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nfkbia

NFKB inhibitor alpha

PID:200154

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

Nos2

nitric oxide synthase 2

PID:200154

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200154

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200154

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

RELA proto-oncogene, NF-kB subunit

PID:200154

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

suppressor of cytokine signaling 3

PID:200154

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

signal transducer and activator of transcription 1

PID:200154

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 3

PID:200154

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

Stat4

signal transducer and activator of transcription 4

PID:200154

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 5A

PID:200154

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Tnf

tumor necrosis factor

PID:200154

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tyk2

tyrosine kinase 2

PID:200154

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

interleukin-27 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ebi3

Epstein-Barr virus induced 3

PID:200028

NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544

Gata3

GATA binding protein 3

PID:200028

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

interferon gamma

PID:200028

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Il12a

interleukin 12A

PID:200028

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

interleukin 12B

PID:200028

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

interleukin 12 receptor subunit beta 1

PID:200028

NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769

Il12rb2

interleukin 12 receptor subunit beta 2

PID:200028

NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289

Il17a

interleukin 17A

PID:200028

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

interleukin 18

PID:200028

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

interleukin 1 beta

PID:200028

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

interleukin 2

PID:200028

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il27

interleukin 27

PID:200028

NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582

Il27ra

interleukin 27 receptor subunit alpha

PID:200028

NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938

Il6

interleukin 6

PID:200028

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Il6st

interleukin 6 cytokine family signal transducer

PID:200028

NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936

Jak1

Janus kinase 1

PID:200028

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

Janus kinase 2

PID:200028

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

signal transducer and activator of transcription 1

PID:200028

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Stat2

signal transducer and activator of transcription 2

PID:200028

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

signal transducer and activator of transcription 3

PID:200028

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

Stat4

signal transducer and activator of transcription 4

PID:200028

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

signal transducer and activator of transcription 5A

PID:200028

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Tbx21

T-box transcription factor 21

PID:200028

NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831

Tgfb1

transforming growth factor, beta 1

PID:200028

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tnf

tumor necrosis factor

PID:200028

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tyk2

tyrosine kinase 2

PID:200028

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

interleukin-3 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcl2l1

Bcl2-like 1

PID:200145

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

Cebpb

CCAAT/enhancer binding protein beta

PID:200145

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

cytokine inducible SH2-containing protein

PID:200145

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

Cnksr1

connector enhancer of kinase suppressor of Ras 1

PID:200145

NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212

colony stimulating factor 2 receptor subunit beta

PID:200145

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

Gab2

GRB2-associated binding protein 2

PID:200145

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

growth factor receptor bound protein 2

PID:200145

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Hdac1

histone deacetylase 1

PID:200145

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

Id1

inhibitor of DNA binding 1

PID:200145

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

Il3

interleukin 3

PID:200145

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

Il3ra

interleukin 3 receptor subunit alpha

PID:200145

NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484

inositol polyphosphate-5-phosphatase D

PID:200145

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Janus kinase 2

PID:200145

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Osm

oncostatin M

PID:200145

NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200145

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200145

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Pim1

Pim-1 proto-oncogene, serine/threonine kinase

PID:200145

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

Prkaca

protein kinase cAMP-activated catalytic subunit alpha

PID:200145

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

Prkacb

protein kinase cAMP-activated catalytic subunit beta

PID:200145

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

protein tyrosine phosphatase, non-receptor type 11

PID:200145

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

SHC adaptor protein 1

PID:200145

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

Srp9

signal recognition particle 9

PID:200145

NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720

signal transducer and activator of transcription 5A

PID:200145

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

signal transducer and activator of transcription 5B

PID:200145

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Ywhag

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

PID:200145

NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827

Ywhaz

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

PID:200145

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

interleukin-4 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aicda

activation-induced cytidine deaminase

PID:200022

NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972

Akt1

AKT serine/threonine kinase 1

PID:200022

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Alox15

arachidonate 15-lipoxygenase

PID:200022

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

Arg1

arginase 1

PID:200022

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Bcl6

BCL6, transcription repressor

PID:200022

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

Cbl

Cbl proto-oncogene

PID:200022

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

Ccl11

C-C motif chemokine ligand 11

PID:200022

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

Ccl17

C-C motif chemokine ligand 17

PID:200022

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

Ccl26

C-C motif chemokine ligand 26

PID:200022

NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335

Cd40lg

CD40 ligand

PID:200022

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

Cebpb

CCAAT/enhancer binding protein beta

PID:200022

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

Col1a1

collagen type I alpha 1 chain

PID:200022

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

Col1a2

collagen type I alpha 2 chain

PID:200022

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

Dok2

docking protein 2

PID:200022

NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402

Egr2

early growth response 2

PID:200022

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

Ets1

ETS proto-oncogene 1, transcription factor

PID:200022

NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010

Fcer2

Fc epsilon receptor II

PID:200022

NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476

Fes

FES proto-oncogene, tyrosine kinase

PID:200022

NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934

growth factor receptor bound protein 2

PID:200022

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Gtf3a

general transcription factor III A

PID:200022

NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690

Hmga1

high mobility group AT-hook 1

PID:200022

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

Ighe

immunoglobulin heavy constant epsilon

PID:200022

Ighg1

immunoglobulin heavy constant gamma 1

PID:200022

Ensembl chr 6:132,389,370...132,393,397

Il10

interleukin 10

PID:200022

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il13ra1

interleukin 13 receptor subunit alpha 1

PID:200022

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

Il13ra1-ps1

interleukin 13 receptor subunit alpha 1, pseudogene 1

PID:200022

NCBI chr11:71,255,035...71,258,723
Ensembl chr11:71,254,928...71,258,678

Il13ra2

interleukin 13 receptor subunit alpha 2

PID:200022

NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381

interleukin 2 receptor subunit gamma

PID:200022

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

Il4

interleukin 4

PID:200022

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il4r

interleukin 4 receptor

PID:200022

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

Il5

interleukin 5

PID:200022

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

inositol polyphosphate-5-phosphatase D

PID:200022

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Irf4

interferon regulatory factor 4

PID:200022

NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070

Irs1

insulin receptor substrate 1

PID:200022

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

Irs2

insulin receptor substrate 2

PID:200022

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

Itgb3

integrin subunit beta 3

PID:200022

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

Jak1

Janus kinase 1

PID:200022

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

Janus kinase 2

PID:200022

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Jak3

Janus kinase 3

PID:200022

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

Lta

lymphotoxin alpha

PID:200022

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

mitogen activated protein kinase 14

PID:200022

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

Mtor

mechanistic target of rapamycin kinase

PID:200022

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

Myb

MYB proto-oncogene, transcription factor

PID:200022

NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057

Mybl1

MYB proto-oncogene like 1

PID:200022

NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183

Oprm1

opioid receptor, mu 1

PID:200022

NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409

Parp14

poly (ADP-ribose) polymerase family, member 14

PID:200022

NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916

Pigr

polymeric immunoglobulin receptor

PID:200022

NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200022

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200022

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

PID:200022

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Retnlb

resistin like beta

PID:200022

NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368

Rps6kb1

ribosomal protein S6 kinase B1

PID:200022

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

Selp

selectin P

PID:200022

NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845

SHC adaptor protein 1

PID:200022

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

Socs1

suppressor of cytokine signaling 1

PID:200022

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

suppressor of cytokine signaling 3

PID:200022

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

Socs5

suppressor of cytokine signaling 5

PID:200022

NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834

Sp1

Sp1 transcription factor

PID:200022

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

Spi1

Spi-1 proto-oncogene

PID:200022

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

signal transducer and activator of transcription 5A

PID:200022

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

signal transducer and activator of transcription 5B

PID:200022

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Stat6

signal transducer and activator of transcription 6

PID:200022

NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495

Tff3

trefoil factor 3

PID:200022

NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054

Thy1

Thy-1 cell surface antigen

PID:200022

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

interleukin-5 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cytokine inducible SH2-containing protein

PID:200107

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

colony stimulating factor 2 receptor subunit beta

PID:200107

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

growth factor receptor bound protein 2

PID:200107

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Il5

interleukin 5

PID:200107

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

Il5ra

interleukin 5 receptor subunit alpha

PID:200107

NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544

Janus kinase 2

PID:200107

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

LYN proto-oncogene, Src family tyrosine kinase

PID:200107

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200107

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1