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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:facilitative sugar transporter mediated glucose transport pathway
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Accession:PW:0000560 term browser browse the term
Definition:The GLUT family contains 14 members in mammals which can be grouped into 3 classes based on sequence similarities. The members of group I (best characterized) and of group III transporters facilitate glucose transport.
Synonyms:related_synonym: GLUT mediated glucose transport pathway


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facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 ISO RGD PMID:15449578 PMID:2211693 PMID:15466941 RGD:1626159, RGD:2303167, RGD:1625539 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 ISO RGD PMID:15449578 RGD:1626159 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 ISO RGD PMID:15449578 PMID:15466941 RGD:1626159, RGD:1625539 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 ISO RGD PMID:15449578 PMID:15466941 RGD:1626159, RGD:1625539 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
altered insulin responsive facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 thymoma viral proto-oncogene 2 ISO RGD PMID:21979934 RGD:7248543 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO RGD PMID:19470471 RGD:7248544 NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627 		JBrowse link
insulin responsive facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti ISO PID PID:200196 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932 		JBrowse link
G Actr2 actin related protein 2 ISO RGD PMID:20739464 RGD:10054052 NCBI chr11:20,012,304...20,062,951
Ensembl chr11:20,012,304...20,062,913 		JBrowse link
G Actr3 ARP3 actin-related protein 3 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 1:125,320,642...125,363,464
Ensembl chr 1:125,320,642...125,363,464 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 ISO PID
RGD		 PMID:11311245 PID:200196, RGD:2306432 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 ISO PID
RGD		 PMID:17629673 PMID:18570632 PMID:11311245 PID:200196, RGD:2302395, RGD:2302397, RGD:2306432 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO RGD PMID:20739464 RGD:10054052 NCBI chr 5:145,020,679...145,045,566
Ensembl chr 5:145,020,640...145,045,571 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B ISO RGD PMID:20739464 RGD:10054052 NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 1:74,275,656...74,307,368
Ensembl chr 1:74,275,243...74,307,368 		JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 5:122,529,941...122,544,244
Ensembl chr 5:122,529,941...122,552,247 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 1:152,642,293...152,651,331
Ensembl chr 1:152,642,293...152,651,348 		JBrowse link
G Baiap2 brain-specific angiogenesis inhibitor 1-associated protein 2 ISO RGD PMID:24613967 RGD:10053654 NCBI chr11:119,833,762...119,897,608
Ensembl chr11:119,833,589...119,897,608 		JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200196 NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073 		JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200196 NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363 		JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200196 NCBI chr 7:16,649,304...16,657,957
Ensembl chr 7:16,649,304...16,658,039 		JBrowse link
G Cbl Casitas B-lineage lymphoma ISO RGD PMID:24613967 RGD:10053654 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346 		JBrowse link
G Cfl1 cofilin 1, non-muscle ISO RGD PMID:20739464 RGD:10054052 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229 		JBrowse link
G Crk v-crk avian sarcoma virus CT10 oncogene homolog ISO RGD PMID:24613967 RGD:10053654 NCBI chr11:75,570,020...75,599,254
Ensembl chr11:75,570,085...75,597,734 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 7:55,491,556...55,582,381
Ensembl chr 7:55,491,493...55,582,350 		JBrowse link
G Dennd1c DENN domain containing 1C ISO RGD PMID:24598362 RGD:10053653 NCBI chr17:57,373,051...57,385,518
Ensembl chr17:57,372,905...57,385,514 		JBrowse link
G Dennd4a DENN domain containing 4A ISO RGD PMID:24598362 RGD:10053653 NCBI chr 9:64,713,408...64,826,949
Ensembl chr 9:64,718,622...64,826,949 		JBrowse link
G Dennd4b DENN domain containing 4B ISO RGD PMID:24598362 RGD:10053653 NCBI chr 3:90,172,281...90,187,972
Ensembl chr 3:90,172,492...90,187,976 		JBrowse link
G Dennd4c DENN domain containing 4C ISO RGD PMID:24598362 RGD:10053653 NCBI chr 4:86,666,761...86,768,841
Ensembl chr 4:86,666,792...86,768,840 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200196 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gys1 glycogen synthase 1, muscle ISO PID PID:200196 NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043 		JBrowse link
G Ins2 insulin II ISO PID PID:200196 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Insr insulin receptor ISO PID PID:200196 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722 		JBrowse link
G Kif3a kinesin family member 3A ISO RGD PMID:24613967 RGD:10053654 NCBI chr11:53,456,531...53,495,075
Ensembl chr11:53,458,206...53,492,794 		JBrowse link
G Kif5b kinesin family member 5B ISO RGD PMID:24613967 RGD:10053654 NCBI chr18:6,201,005...6,241,524
Ensembl chr18:6,201,002...6,242,174 		JBrowse link
G Limk1 LIM domain kinase 1 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 5:134,684,893...134,718,713
Ensembl chr 5:134,684,893...134,717,452 		JBrowse link
G Lnpep leucyl/cystinyl aminopeptidase ISO PID
RGD		 PMID:17717074 PMID:16967782 PID:200196, RGD:2302393, RGD:2306436 NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312 		JBrowse link
G Myo1c myosin IC ISO RGD PMID:24613967 RGD:10053654 NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736 		JBrowse link
G Myo5a myosin VA ISO RGD PMID:18570632 PMID:24613967 RGD:2302397, RGD:10053654 NCBI chr 9:74,975,183...75,130,970
Ensembl chr 9:74,978,297...75,130,970 		JBrowse link
G Myo5b myosin VB ISO RGD PMID:24613967 RGD:10053654 NCBI chr18:74,575,435...74,905,769
Ensembl chr18:74,574,007...74,904,564 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588 		JBrowse link
G Plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 8:106,096,272...106,109,492
Ensembl chr 8:106,099,906...106,109,494 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO PID PID:200196 NCBI chr 5:122,296,338...122,313,336
Ensembl chr 5:122,296,341...122,313,336 		JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A ISO PID PID:200196 NCBI chr 6:14,713,821...14,755,273
Ensembl chr 6:14,713,976...14,755,273 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 2:166,408,265...166,555,752
Ensembl chr 2:166,408,262...166,555,752 		JBrowse link
G Prkci protein kinase C, iota ISO PID PID:200196 NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108 		JBrowse link
G Prkcz protein kinase C, zeta ISO PID PID:200196 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818 		JBrowse link
G Rab10 RAB10, member RAS oncogene family ISO
TAS		 RGD PMID:17717074 PMID:24598362 PMID:18570632 PMID:17629673 RGD:2302393, RGD:10053653, RGD:2302397, RGD:2302395 NCBI chr12:3,297,428...3,359,969
Ensembl chr12:3,297,428...3,359,969 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:17629673 PMID:18570632 RGD:2302395, RGD:2302397 NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040 		JBrowse link
G Rab13 RAB13, member RAS oncogene family ISO RGD PMID:24598362 RGD:10053653 NCBI chr 3:90,121,022...90,133,694
Ensembl chr 3:90,121,002...90,133,692 		JBrowse link
G Rab14 RAB14, member RAS oncogene family ISO RGD PMID:17717074 PMID:18701652 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2306295, RGD:2302397, RGD:2302395 NCBI chr 2:35,070,217...35,091,132
Ensembl chr 2:35,070,217...35,091,132 		JBrowse link
G Rab2a RAB2A, member RAS oncogene family ISO RGD PMID:17717074 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2302397, RGD:2302395 NCBI chr 4:8,535,661...8,607,708
Ensembl chr 4:8,535,644...8,607,778 		JBrowse link
G Rab3ip RAB3A interacting protein ISO RGD PMID:24598362 RGD:10053653 NCBI chr10:116,741,685...116,786,361
Ensembl chr10:116,741,689...116,786,674 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family ISO RGD PMID:17629673 PMID:8013658 PMID:18570632 RGD:2302395, RGD:2306268, RGD:2302397 NCBI chr 8:124,532,748...124,562,030
Ensembl chr 8:124,532,724...124,562,026 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family ISO RGD PMID:17629673 RGD:2302395 NCBI chr17:53,786,262...53,814,706
Ensembl chr17:53,786,262...53,814,708 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family ISO RGD PMID:17717074 PMID:18701652 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2306295, RGD:2302397, RGD:2302395 NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748 		JBrowse link
G Rab8b RAB8B, member RAS oncogene family ISO RGD PMID:18570632 RGD:2302397 NCBI chr 9:66,750,891...66,826,987
Ensembl chr 9:66,750,946...66,826,969 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 2:29,509,732...29,630,376
Ensembl chr 2:29,509,732...29,630,990 		JBrowse link
G Rhoq ras homolog family member Q ISO PID
RGD		 PMID:24613967 PID:200196, RGD:10053654 NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497 		JBrowse link
G Sfn stratifin ISO PID PID:200196 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 ISO PID
RGD		 PMID:17717074 PMID:8013658 PMID:2211693 PMID:18570632 PMID:17629673 PID:200196, RGD:2302393, RGD:2306268, RGD:2303167, RGD:2302397, RGD:2302395 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Snap23 synaptosomal-associated protein 23 ISO RGD PMID:17717074 PMID:18570632 RGD:2302393, RGD:2302397 NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr19:40,280,484...40,502,399
Ensembl chr19:40,283,197...40,502,223 		JBrowse link
G Ssh1 slingshot protein phosphatase 1 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 5:114,075,155...114,131,864
Ensembl chr 5:114,075,155...114,131,955 		JBrowse link
G Stx4a syntaxin 4A (placental) ISO PID
RGD		 PMID:17717074 PMID:18570632 PID:200196, RGD:2302393, RGD:2302397 NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191 		JBrowse link
G Stxbp3 syntaxin binding protein 3 ISO RGD PMID:17717074 PMID:18570632 RGD:2302393, RGD:2302397 NCBI chr 3:108,700,496...108,747,818
Ensembl chr 3:108,700,492...108,747,842 		JBrowse link
G Stxbp4 syntaxin binding protein 4 ISO PID
RGD		 PMID:17629673 PID:200196, RGD:2302395 NCBI chr11:90,367,318...90,528,962
Ensembl chr11:90,367,318...90,528,910 		JBrowse link
G Tbc1d1 TBC1 domain family, member 1 ISO RGD PMID:24598362 RGD:10053653 NCBI chr 5:64,313,648...64,508,829
Ensembl chr 5:64,313,648...64,508,829 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO PID
RGD		 PMID:17717074 PMID:18570632 PID:200196, RGD:2302393, RGD:2302397 NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627 		JBrowse link
G Tiam1 T cell lymphoma invasion and metastasis 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr16:89,583,999...89,942,488
Ensembl chr16:89,583,999...89,940,657 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 ISO PID PID:200196 NCBI chr17:57,540,227...57,570,712
Ensembl chr17:57,556,455...57,570,665 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO PID
RGD		 PMID:17717074 PMID:18570632 PID:200196, RGD:2302393, RGD:2302397 NCBI chr11:68,979,354...68,983,207
Ensembl chr11:68,979,316...68,983,210 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide ISO PID PID:200196 NCBI chr 2:163,837,082...163,860,508
Ensembl chr 2:163,836,880...163,860,508 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide ISO PID PID:200196 NCBI chr11:75,620,121...75,656,667
Ensembl chr11:75,623,695...75,656,671 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide ISO PID PID:200196 NCBI chr 5:135,937,233...135,963,495
Ensembl chr 5:135,937,263...135,963,470 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide ISO PID PID:200196 NCBI chr 5:33,176,160...33,185,310
Ensembl chr 5:33,176,160...33,185,310 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta ISO PID PID:200196 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide ISO PID PID:200196 NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6072
    regulatory pathway 3689
      transport pathway 357
        sugar transport pathway 79
          glucose transport pathway 79
            facilitative sugar transporter mediated glucose transport pathway 77
              altered facilitative sugar transporter mediated glucose transport pathway + 2
              insulin responsive facilitative sugar transporter mediated glucose transport pathway + 74
paths to the root