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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA decay pathway
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Accession:PW:0000546 term browser browse the term
Definition:The pathways of mRNA quality control thereby erroneous mRNA is degraded in the nucleus or cytoplasm, or normal mRNA accumulated in the nucleus is degraded.
Synonyms:exact_synonym: mRNA quality control pathway;   mRNA surveillance pathway
 related_synonym: KEGG:03015


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mRNA decay pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acin1 apoptotic chromatin condensation inducer 1 JBrowse link 15 33,288,369 33,333,256 RGD:6907045
G Alyref Aly/REF export factor JBrowse link 10 109,768,593 109,774,639 RGD:6907045
G Casc3 CASC3 exon junction complex subunit JBrowse link 10 86,724,534 86,744,485 RGD:6907045
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 JBrowse link 3 72,125,269 72,137,122 RGD:6907045
G Cpsf1 cleavage and polyadenylation specific factor 1 JBrowse link 7 117,661,779 117,672,373 RGD:6907045
G Cpsf2 cleavage and polyadenylation specific factor 2 JBrowse link 6 125,870,372 125,898,039 RGD:6907045
G Cpsf3 cleavage and polyadenylation specific factor 3 JBrowse link 6 43,363,792 43,391,712 RGD:6907045
G Cpsf4 cleavage and polyadenylation specific factor 4 JBrowse link 12 11,199,893 11,215,690 RGD:6907045
G Cpsf6 cleavage and polyadenylation specific factor 6 JBrowse link 7 60,385,688 60,417,661 RGD:6907045
G Cpsf7 cleavage and polyadenylation specific factor 7 JBrowse link 1 226,572,399 226,596,185 RGD:6907045
G Cstf1 cleavage stimulation factor subunit 1 JBrowse link 3 170,380,413 170,392,162 RGD:6907045
G Cstf2 cleavage stimulation factor subunit 2 JBrowse link X 104,882,726 104,909,746 RGD:6907045
G Cstf2t cleavage stimulation factor subunit 2, tau variant JBrowse link 1 249,574,954 249,578,520 RGD:6907045
G Cstf3 cleavage stimulation factor subunit 3 JBrowse link 3 94,530,586 94,603,378 RGD:6907045
G Dazap1 DAZ associated protein 1 JBrowse link 7 12,289,895 12,315,897 RGD:6907045
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:6907045
G Etf1 eukaryotic translation termination factor 1 JBrowse link 18 27,698,693 27,725,694 RGD:6907045
G Fip1l1 factor interacting with PAPOLA and CPSF1 JBrowse link 14 36,150,381 36,208,395 RGD:6907045
G Gspt1 G1 to S phase transition 1 JBrowse link 10 4,313,100 4,347,661 RGD:6907045
G Gspt2 G1 to S phase transition 2 JBrowse link X 63,959,131 63,961,652 RGD:6907045
G Hbs1l HBS1-like translational GTPase JBrowse link 1 16,819,170 16,896,234 RGD:6907045
G Magoh mago homolog, exon junction complex subunit JBrowse link 5 127,480,465 127,487,617 RGD:6907045
G Magohb mago homolog B, exon junction complex subunit JBrowse link 4 165,514,584 165,522,366 RGD:6907045
G Msi1 musashi RNA-binding protein 1 JBrowse link 12 46,899,835 46,935,335 RGD:6907045
G Msi2 musashi RNA-binding protein 2 JBrowse link 10 75,673,840 76,040,106 RGD:6907045
G Ncbp1 nuclear cap binding protein subunit 1 JBrowse link 5 61,734,118 61,767,098 RGD:6907045
G Nudt21 nudix hydrolase 21 JBrowse link 19 11,451,366 11,470,637 RGD:6907045
G Nxf1 nuclear RNA export factor 1 JBrowse link 1 224,957,535 224,970,728 RGD:6907045
G Nxf3 nuclear RNA export factor 3 JBrowse link X 106,562,957 106,587,487 RGD:6907045
G Nxf7 nuclear RNA export factor 7 JBrowse link X 106,049,075 106,066,334 RGD:6907045
G Nxt1 nuclear transport factor 2-like export factor 1 JBrowse link 3 142,993,658 142,996,580 RGD:6907045
G Nxt2 nuclear transport factor 2-like export factor 2 JBrowse link X 113,509,841 113,517,112 RGD:6907045
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 7 75,409,581 75,421,874 RGD:6907045
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like JBrowse link 3 160,410,733 160,447,073 RGD:6907045
G Pabpc1l2a poly(A) binding protein, cytoplasmic 1-like 2A JBrowse link X 73,894,603 73,895,742 RGD:6907045
G Pabpc2 poly(A) binding protein, cytoplasmic 2 JBrowse link 18 32,964,763 32,967,031 RGD:6907045
G Pabpc4 poly(A) binding protein, cytoplasmic 4 JBrowse link 5 140,978,893 140,994,732 RGD:6907045
G Pabpc4l poly(A) binding protein, cytoplasmic 4-like JBrowse link 2 130,656,212 130,658,202 RGD:6907045
G Pabpc5 poly A binding protein, cytoplasmic 5 JBrowse link X 92,130,292 92,133,756 RGD:6907045
G Pabpn1 poly(A) binding protein, nuclear 1 JBrowse link 15 33,555,640 33,560,251 RGD:6907045
G Pabpn1l poly(A)binding protein nuclear 1-like JBrowse link 19 55,430,808 55,434,252 RGD:6907045
G Papola poly (A) polymerase alpha JBrowse link 6 129,609,068 129,662,002 RGD:6907045
G Papolb poly(A) polymerase beta JBrowse link 12 14,112,426 14,114,772 RGD:6907045
G Papolg poly(A) polymerase gamma JBrowse link 14 108,624,359 108,658,371 RGD:6907045
G Pcf11 PCF11 cleavage and polyadenylation factor subunit JBrowse link 1 157,463,014 157,494,134 RGD:6907045
G Pelo pelota mRNA surveillance and ribosome rescue factor JBrowse link 2 47,266,758 47,268,526 RGD:6907045
G Pigz phosphatidylinositol glycan anchor biosynthesis, class Z JBrowse link 11 72,930,040 72,936,002 RGD:6907045
G Pnn pinin, desmosome associated protein JBrowse link 6 80,159,364 80,167,677 RGD:6907045
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:6907045
G Ppp2cb protein phosphatase 2 catalytic subunit beta JBrowse link 16 62,273,276 62,294,767 RGD:6907045
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:6907045
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta JBrowse link 8 55,279,278 55,311,768 RGD:6907045
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha JBrowse link 15 43,673,958 43,733,182 RGD:6907045
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta JBrowse link 18 36,985,709 37,421,383 RGD:6907045
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma JBrowse link 14 78,679,214 78,763,175 RGD:6907045
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta JBrowse link 1 211,205,903 211,240,216 RGD:6907045
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha JBrowse link 8 109,481,352 109,621,462 RGD:6907045
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma JBrowse link 6 76,056,585 76,079,755 RGD:6907045
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha JBrowse link 13 110,033,550 110,077,946 RGD:6907045
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta JBrowse link 1 221,597,294 221,605,467 RGD:6907045
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:6907045
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta JBrowse link 9 16,580,995 16,610,425 RGD:6907045
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon JBrowse link 6 98,417,974 98,567,016 RGD:6907045
G Pym1 PYM homolog 1, exon junction complex associated factor JBrowse link 7 3,172,798 3,193,994 RGD:6907045
G Rbm8a RNA binding motif protein 8A JBrowse link 2 198,755,261 198,758,028 RGD:6907045
G RGD1309489 similar to Est1p-like protein B JBrowse link 7 83,691,630 83,804,882 RGD:6907045
G RGD1561590 similar to SAP18 JBrowse link 10 89,635,651 89,636,271 RGD:6907045
G Rngtt RNA guanylyltransferase and 5'-phosphatase JBrowse link 5 48,561,325 48,779,214 RGD:6907045
G Rnmt RNA (guanine-7-) methyltransferase JBrowse link 18 64,084,746 64,108,246 RGD:6907045
G Rnps1 RNA binding protein with serine rich domain 1 JBrowse link 10 13,786,339 13,796,720 RGD:6907045
G Sap18 Sin3A associated protein 18 JBrowse link 15 38,069,320 38,073,625 RGD:6907045
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:6907045
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:6907045
G Smg7 SMG7 nonsense mediated mRNA decay factor JBrowse link 13 70,258,919 70,321,886 RGD:6907045
G Srrm1 serine and arginine repetitive matrix 1 JBrowse link 5 153,675,619 153,708,187 RGD:6907045
G Sympk symplekin JBrowse link 1 79,931,097 79,959,461 RGD:6907045
G Upf2 UPF2, regulator of nonsense mediated mRNA decay JBrowse link 17 76,176,379 76,287,246 RGD:6907045
G Upf3a UPF3A, regulator of nonsense mediated mRNA decay JBrowse link 16 81,521,084 81,532,512 RGD:6907045
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay JBrowse link X 123,713,327 123,731,431 RGD:6907045

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6064
    regulatory pathway 3843
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1723
        RNA processing pathway 289
          RNA degradation pathway 137
            mRNA decay pathway 79
              Staufen-mediated mRNA decay pathway 0
              altered mRNA decay pathway 0
              exosome mediated RNA decay pathway 0
              no-go mRNA decay pathway 0
              nonsense-mediated mRNA decay pathway 0
              nonstop mRNA decay pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.