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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:angiotensin III signaling pathway via AT1 receptor
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Accession:PW:0000530 term browser browse the term
Definition:Angiotensin III, like angiotensin II, binds to the type 1 and 2 receptors and triggers downstream signaling pathways. In rats, angiotensin III signaling through the receptor type 1 (AT1) can modulate noradrenergic transmission via phospholipase C activation.



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angiotensin III signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11100981 RGD:1582152 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    signaling pathway 1939
      hormone signaling pathway 379
        peptide and protein hormone signaling pathway 273
          angiotensin signaling pathway 40
            angiotensin III signaling pathway 4
              angiotensin III signaling pathway via AT1 receptor 2
Path 2
Term Annotations click to browse term
  pathway 4052
    regulatory pathway 2511
      homeostasis pathway 1305
        cardiovascular system homeostasis pathway 264
          renin-angiotensin cascade pathway 44
            angiotensin signaling pathway 40
              angiotensin III signaling pathway 4
                angiotensin III signaling pathway via AT1 receptor 2
paths to the root