angiotensin (1-7) signaling pathway - Ontology Report - Rat Genome Database

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PATHWAY ONTOLOGY - ANNOTATIONS	{{ watchLinkText }}
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:	angiotensin (1-7) signaling pathway	go back to main search page
Accession:	PW:0000529	browse the term
Definition:	Angiotensin (1-7) is derived from angiotensin II through the action of angiotensin converting enzyme 2 (ACE2) or from angiotensin I through the action of neutral endopeptidase (NEP). Angiotensin (1-7) signaling appears to have a vasodilatory effect but the exact action of this peptide in humans remains to be established.

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Genes (4)

angiotensin (1-7) signaling pathway

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin converting enzyme 2

NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702

G

angiotensinogen

NCBI chrNW_004936484:19,713,299...19,721,144
Ensembl chrNW_004936484:19,716,165...19,721,261

G

angiotensin-converting enzyme

PMID:10642323 PMID:15283675

RGD:1581953 RGD:1598433

NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177

G

membrane metalloendopeptidase

PMID:10642323 PMID:15638741 PMID:16520407

RGD:1581742 RGD:1581931 RGD:1581953

NCBI chrNW_004936519:2,513,896...2,595,896
Ensembl chrNW_004936519:2,513,704...2,595,971

Term paths to the root

Path 1
Term	Annotations
pathway	3947
signaling pathway	1893
hormone signaling pathway	368
peptide and protein hormone signaling pathway	263
angiotensin signaling pathway	37
angiotensin (1-7) signaling pathway	4
Path 2
Term	Annotations
pathway	3947
regulatory pathway	2449
homeostasis pathway	1274
cardiovascular system homeostasis pathway	256
renin-angiotensin cascade pathway	41
angiotensin signaling pathway	37
angiotensin (1-7) signaling pathway	4

paths to the root