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The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:angiotensin (1-7) signaling pathway
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Accession:PW:0000529 term browser browse the term
Definition:Angiotensin (1-7) is derived from angiotensin II through the action of angiotensin converting enzyme 2 (ACE2) or from angiotensin I through the action of neutral endopeptidase (NEP). Angiotensin (1-7) signaling appears to have a vasodilatory effect but the exact action of this peptide in humans remains to be established.

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angiotensin (1-7) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:10642323 PMID:15283675 RGD:1581953 RGD:1598433 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO RGD PMID:15638741 RGD:1581742 NCBI chr  X:11,798,839...11,839,591
Ensembl chr  X:11,798,839...11,900,594
JBrowse link
G AGT angiotensinogen ISO RGD PMID:15951342 RGD:1581938 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:15951342 PMID:16520407 RGD:1581931 RGD:1581938 NCBI chr 1:49,090,041...49,105,244
Ensembl chr 1:49,090,041...49,105,244
JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:10642323 PMID:15638741 PMID:16520407 RGD:1581742 RGD:1581931 RGD:1581953 NCBI chr23:48,966,222...49,059,919
Ensembl chr23:48,971,066...49,059,919
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    signaling pathway 1936
      hormone signaling pathway 379
        peptide and protein hormone signaling pathway 273
          angiotensin signaling pathway 40
            angiotensin (1-7) signaling pathway 5
Path 2
Term Annotations click to browse term
  pathway 4047
    regulatory pathway 2507
      homeostasis pathway 1304
        cardiovascular system homeostasis pathway 263
          renin-angiotensin cascade pathway 44
            angiotensin signaling pathway 40
              angiotensin (1-7) signaling pathway 5
paths to the root