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ONTOLOGY REPORT - ANNOTATIONS


Term:linoleic acid metabolic pathway
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Accession:PW:0000523 term browser browse the term
Definition:Those enzymatic reactions involved in the synthesis, utilization or degradation of linoleic acid - an unsaturated omega-6 fatty acid. Linoleic acid is an essential fatty acid that humans and other animals cannot synthesize and must obtain from diet.
Synonyms:related_synonym: KEGG:00591;   SMP:00018


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linoleic acid metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1B10 aldo-keto reductase family 1 member B10 JBrowse link 7 134,527,567 134,541,412 RGD:6907045
G ALOX15 arachidonate 15-lipoxygenase JBrowse link 17 4,630,919 4,641,678 RGD:6907045
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6907045
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 JBrowse link 10 94,683,729 94,736,190 RGD:6907045
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 JBrowse link 10 94,762,681 94,855,547 RGD:6907045
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 JBrowse link 10 95,036,772 95,069,497 RGD:6907045
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6907045
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6907045
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 JBrowse link 1 59,893,308 59,926,798 RGD:6907045
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6907045
G CYP3A43 cytochrome P450 family 3 subfamily A member 43 JBrowse link 7 99,827,626 99,867,138 RGD:6907045
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 JBrowse link 7 99,648,194 99,679,996 RGD:6907045
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 JBrowse link 7 99,705,036 99,735,196 RGD:6907045
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 JBrowse link 1 47,137,425 47,149,738 RGD:9068941
G ELOVL4 ELOVL fatty acid elongase 4 JBrowse link 6 79,914,814 79,947,553 RGD:10402751
G ELOVL5 ELOVL fatty acid elongase 5 JBrowse link 6 53,267,398 53,349,179 RGD:10402751
G FADS1 fatty acid desaturase 1 JBrowse link 11 61,799,627 61,817,003 RGD:10402751
G FADS2 fatty acid desaturase 2 JBrowse link 11 61,816,203 61,867,354 RGD:10402751
G JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough JBrowse link 15 41,828,085 41,848,148 RGD:6907045
G PLA2G10 phospholipase A2 group X JBrowse link 16 14,672,548 14,694,662 RGD:6907045
G PLA2G12A phospholipase A2 group XIIA JBrowse link 4 109,709,989 109,730,070 RGD:6907045
G PLA2G12B phospholipase A2 group XIIB JBrowse link 10 72,934,762 72,955,044 RGD:6907045
G PLA2G1B phospholipase A2 group IB JBrowse link 12 120,322,115 120,327,779 RGD:6907045
G PLA2G2A phospholipase A2 group IIA JBrowse link 1 19,975,431 19,980,434 RGD:6907045
G PLA2G2C phospholipase A2 group IIC JBrowse link 1
1
20,163,055
20,184,242
20,186,518
20,186,486
RGD:6907045
G PLA2G2D phospholipase A2 group IID JBrowse link 1 20,111,939 20,119,566 RGD:6907045
G PLA2G2E phospholipase A2 group IIE JBrowse link 1 19,920,009 19,923,617 RGD:6907045
G PLA2G2F phospholipase A2 group IIF JBrowse link 1 20,139,323 20,150,386 RGD:6907045
G PLA2G3 phospholipase A2 group III JBrowse link 22 31,134,807 31,140,508 RGD:6907045
G PLA2G4A phospholipase A2 group IVA JBrowse link 1 186,828,949 186,988,981 RGD:6907045
G PLA2G4B phospholipase A2 group IVB JBrowse link 15 41,838,813 41,848,148 RGD:6907045
RGD:10402751
G PLA2G4E phospholipase A2 group IVE JBrowse link 15 41,981,582 42,050,703 RGD:6907045
G PLA2G5 phospholipase A2 group V JBrowse link 1 20,028,349 20,091,911 RGD:6907045
G PLA2G6 phospholipase A2 group VI JBrowse link 22 38,111,495 38,181,830 RGD:6907045
G PLB1 phospholipase B1 JBrowse link 2 28,488,578 28,644,142 RGD:6907045

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5951
    classic metabolic pathway 1802
      lipid metabolic pathway 431
        fatty acid metabolic pathway 143
          linoleic acid metabolic pathway 35
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.