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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:atherosclerosis pathway
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Accession:PW:0000518 term browser browse the term
Definition:A pathway leading to the thickening of medium and large arteries. While lipoprotein related pathways are of interest, monogenic conditions such as those linked to mutations in the laminin gene may also provide clues regarding atherosclerosis pathways.


show annotations for term's descendants           Sort by:
atherosclerosis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:18206890 RGD:5509610 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:12969990 RGD:1581826 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G LMNA lamin A/C ISO RGD PMID:15205220 RGD:1580530 NCBI chr 1:131,456,819...131,482,275
Ensembl chr 1:135,253,700...135,311,539 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:15662225 RGD:1582524 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4069
    disease pathway 714
      cardiovascular system disease pathway 23
        arterial occlusive disease pathway 4
          atherosclerosis pathway 4
paths to the root