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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:reverse cholesterol transport pathway
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Accession:PW:0000498 term browser browse the term
Definition:Reverse cholesterol transport (RCT) is the pathway by which cholesterol from extrahepatic cells/tissue is transported to the liver for excretion. The pathway may prevent the development of atherosclerosis by reducing the accumulation of cholesterol in the walls of arteries.
Synonyms:related_synonym: RCT pathway;   reverse cholesterol transport;   selective cholesterol uptake pathway


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reverse cholesterol transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO
TAS 		RGD PMID:16258026 PMID:16227687 RGD:1600654, RGD:1600659 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Apoa1 apolipoprotein A1 ISO
TAS 		RGD PMID:16258026 PMID:16227687 RGD:1600654, RGD:1600659 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Cav1 caveolin 1 ISO
TAS 		RGD PMID:16258026 PMID:16227687 RGD:1600654, RGD:1600659 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav2 caveolin 2 ISO RGD PMID:16258026 RGD:1600654 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 ISO RGD PMID:16258026 RGD:1600654 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Lcat lecithin cholesterol acyltransferase ISO
TAS 		RGD PMID:16258026 PMID:16227687 RGD:1600654, RGD:1600659 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lipc lipase C, hepatic type ISO
TAS 		RGD PMID:16258026 PMID:16227687 RGD:1600654, RGD:1600659 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Pltp phospholipid transfer protein ISO RGD PMID:16258026 RGD:1600654 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 TAS
ISO 		RGD PMID:14592533 PMID:16258026 PMID:16227687 RGD:1580028, RGD:1600654, RGD:1600659 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
altered reverse cholesterol transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD PMID:11086027 RGD:1600951 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3866
      transport pathway 469
        cholesterol transport pathway 9
          reverse cholesterol transport pathway 9
            altered reverse cholesterol transport pathway 1
paths to the root