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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:vasopressin signaling pathway
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Accession:PW:0000491 term browser browse the term
Definition:The hormone vasopressin plays central roles in cardiovascular and water homeostasis by signaling via two receptor types, G-protein coupled receptors coupling to particular G alpha subunits of heterotrimeric G proteins.
Synonyms:related_synonym: Avp signaling pathway;   arginine-vasopressin signaling pathway

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vasopressin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 ISO RGD PMID:15579502, PMID:18431594, PMID:18971210 RGD:2312654, RGD:2312656, RGD:2313211 NCBI chrNW_004955500:7,635,946...7,655,579
Ensembl chrNW_004955500:7,637,089...7,651,162
JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO RGD PMID:15037626, PMID:18431594 RGD:1303982, RGD:2312656 NCBI chrNW_004955436:11,883,840...12,002,668
Ensembl chrNW_004955436:11,884,433...12,004,013
JBrowse link
G Aqp2 aquaporin 2 ISO RGD PMID:15037626, PMID:15579502, PMID:18431594, PMID:18971210 RGD:1303982, RGD:2312654, RGD:2312656, RGD:2313211 NCBI chrNW_004955547:547,770...555,764
Ensembl chrNW_004955547:547,064...555,958
JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:12942143, PMID:14624682 RGD:1358326, RGD:1579891 NCBI chrNW_004955458:10,245,325...10,253,209
Ensembl chrNW_004955458:10,245,111...10,253,209
JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:7624319, PMID:14624682, PMID:19047484 RGD:1579891, RGD:2312649, RGD:61542 NCBI chrNW_004955406:41,706,088...41,716,173
Ensembl chrNW_004955406:41,705,305...41,716,173
JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO RGD PMID:11882591, PMID:14624682, PMID:18431594, PMID:18971210 RGD:1579891, RGD:2312654, RGD:2312656, RGD:628560 NCBI chrNW_004955580:583,827...586,739
Ensembl chrNW_004955580:583,480...586,456
JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955495:5,286,891...5,302,631
Ensembl chrNW_004955495:5,285,380...5,302,631
JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955512:1,381,159...1,658,409 JBrowse link
G Myo5b myosin VB ISO RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chrNW_004955402:34,892,652...35,247,431 JBrowse link
G Pde4d phosphodiesterase 4D ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653
JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chrNW_004955450:9,638,761...9,656,291
Ensembl chrNW_004955450:9,638,761...9,656,603
JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chrNW_004955431:22,637,605...22,674,107
Ensembl chrNW_004955431:22,634,103...22,674,107
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955422:19,615,440...19,627,195
Ensembl chrNW_004955422:19,615,440...19,627,088
JBrowse link
G Snap23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955416:9,191,123...9,225,103
Ensembl chrNW_004955416:9,190,623...9,225,103
JBrowse link
G Vamp2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955467:8,793,296...8,796,771 JBrowse link
vasopressin signaling pathway via receptor type 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955458:10,245,325...10,253,209
Ensembl chrNW_004955458:10,245,111...10,253,209
JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955406:41,706,088...41,716,173
Ensembl chrNW_004955406:41,705,305...41,716,173
JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955495:5,286,891...5,302,631
Ensembl chrNW_004955495:5,285,380...5,302,631
JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004955512:1,381,159...1,658,409 JBrowse link
vasopressin signaling pathway via receptor type 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00322 NCBI chrNW_004955504:4,990,634...5,376,990
Ensembl chrNW_004955504:5,004,903...5,376,328
JBrowse link
G Adcy6 adenylate cyclase 6 ISO RGD PMID:15579502, PMID:18431594, PMID:18971210 RGD:2312654, RGD:2312656, RGD:2313211 NCBI chrNW_004955500:7,635,946...7,655,579
Ensembl chrNW_004955500:7,637,089...7,651,162
JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO RGD PMID:15037626, PMID:18431594 RGD:1303982, RGD:2312656 NCBI chrNW_004955436:11,883,840...12,002,668
Ensembl chrNW_004955436:11,884,433...12,004,013
JBrowse link
G Aqp2 aquaporin 2 ISO RGD PMID:15037626, PMID:15579502, PMID:18431594, PMID:18971210 RGD:1303982, RGD:2312654, RGD:2312656, RGD:2313211 NCBI chrNW_004955547:547,770...555,764
Ensembl chrNW_004955547:547,064...555,958
JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO SMPDB
RGD
PMID:14624682, PMID:18431594, PMID:18971210 RGD:1579891, RGD:2312654, RGD:2312656, SMP:00322 NCBI chrNW_004955580:583,827...586,739
Ensembl chrNW_004955580:583,480...586,456
JBrowse link
G Fshr follicle stimulating hormone receptor ISO SMPDB SMP:00322 NCBI chrNW_004955441:15,422,190...15,585,446
Ensembl chrNW_004955441:15,422,190...15,585,537
JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00322 NCBI chrNW_004955486:9,165,850...9,192,306
Ensembl chrNW_004955486:9,165,850...9,193,066
JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00322 NCBI chrNW_004955423:23,576,515...23,644,600
Ensembl chrNW_004955423:23,634,402...23,644,600
JBrowse link
G Myo5b myosin VB ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955402:34,892,652...35,247,431 JBrowse link
G Pde4d phosphodiesterase 4D ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00322 NCBI chrNW_004955423:9,630,308...9,747,820
Ensembl chrNW_004955423:9,629,378...9,747,820
JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955450:9,638,761...9,656,291
Ensembl chrNW_004955450:9,638,761...9,656,603
JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955431:22,637,605...22,674,107
Ensembl chrNW_004955431:22,634,103...22,674,107
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955422:19,615,440...19,627,195
Ensembl chrNW_004955422:19,615,440...19,627,088
JBrowse link
G Snap23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955416:9,191,123...9,225,103
Ensembl chrNW_004955416:9,190,623...9,225,103
JBrowse link
G Vamp2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004955467:8,793,296...8,796,771 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3928
    regulatory pathway 2441
      homeostasis pathway 1269
        cardiovascular system homeostasis pathway 258
          vasopressin signaling pathway 20
            altered vasopressin signaling pathway + 0
            vasopressin signaling pathway via receptor type 1 + 4
            vasopressin signaling pathway via receptor type 2 + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.