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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:C-type natriuretic peptide signaling pathway
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Accession:PW:0000473 term browser browse the term
Definition:The role of the C-type signaling pathway is not well established. The receptor for the C-type natriuretic peptide, unlike the receptors for the other two types of peptides, is non-guanylyl cyclase receptor that appears to couple to adenylyl cyclase inhibition/phospholipase C activation via Gi family of G-protein.
Synonyms:related_synonym: C-type brain natriuretic peptide signaling pathway;   CNP signaling pathway


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C-type natriuretic peptide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppc natriuretic peptide C IMP
TAS		 RGD PMID:15337698 PMID:16537417 RGD:1580149, RGD:1601488 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Npr2 natriuretic peptide receptor 2 IMP RGD PMID:16537417 RGD:1601488 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:15044621 RGD:1581459 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
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Path 1
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  pathway 6092
    regulatory pathway 3867
      homeostasis pathway 1773
        cardiovascular system homeostasis pathway 423
          natriuretic peptide signaling pathway 7
            C-type natriuretic peptide signaling pathway 3
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