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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:leukotriene metabolic pathway
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Accession:PW:0000464 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of leukotrienes - a class of eicosanoids whose effects include vasoconstriction and bronchoconstriction.
Synonyms:related_synonym: leukotriene metabolic process


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leukotriene metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO
IMP		 RGD PMID:17517102 PMID:7665580 RGD:2313910, RGD:39128168 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO
IDA		 RGD PMID:18945963 PMID:2300173 RGD:2313900, RGD:69749 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO RGD PMID:17517102 RGD:2313910 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO RGD PMID:17517102 RGD:2313910 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        eicosanoid metabolic pathway 18
          leukotriene metabolic pathway 4
            leukotriene biosynthetic pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          arachidonic acid metabolic pathway 83
            lipoxygenase mediated pathway of arachidonic acid metabolism 9
              leukotriene metabolic pathway 4
                leukotriene biosynthetic pathway 0
paths to the root